I-Tasser Results Output Page Description In Details #3DStrucutre #ProteinModelling #HomologyModelling
Пікірлер: 267
@javeriaaltaf Жыл бұрын
Thank you for describing everything. Your way of lecture delivery is impressive.
@Prof.Dr.MuhammadNaveed Жыл бұрын
pleasures
@muhammadmukheed8594 Жыл бұрын
Sir Thank you for these informative lectures. Previously I think bioinformatics is very tough but after watching your lecture I find it very easy... Thank you.
@ayeshamalik46794 жыл бұрын
Sir your videos are informative for researchers and students also thankful to you
@Prof.Dr.MuhammadNaveed4 жыл бұрын
pleasures
@pawansharma80282 жыл бұрын
Very precise and accurate explanation. Well done.
@Prof.Dr.MuhammadNaveed2 жыл бұрын
pleasures
@tahiraaslam43652 жыл бұрын
Excellent 👍 Sir
@Prof.Dr.MuhammadNaveed2 жыл бұрын
So nice of you
@MayankSingh-uj6hi4 жыл бұрын
Sir aap really best ho thanks
@Prof.Dr.MuhammadNaveed4 жыл бұрын
Thankyou so much
@abubakarbashir79514 жыл бұрын
I can see that you are doing a marvelous job, only that us that cannot hear your language are missing a lot. How I wish you will find way so that you can also go along with us. We will really appreciate that. Thank you, Sir.
@Prof.Dr.MuhammadNaveed4 жыл бұрын
Thanks, dear for the compliment and in near future will deliver lecture in English
@abubakarbashir79514 жыл бұрын
@@Prof.Dr.MuhammadNaveed Thank you so much Dr for the positive response. I really appreciate that.
@tahiraghulam27334 жыл бұрын
Such a nice tutorial. full of knowledge.
@Prof.Dr.MuhammadNaveed4 жыл бұрын
pleasures
@user-bv7zd9xn2v7 ай бұрын
Thanks for describing. Respected Sir, the active site predicted by I Teaser can be used for focused docking?
@ahmedawan59094 жыл бұрын
Sir I understand if rampage shows different values for same protein model in different species is due to differences in secondary structure
@sarahnawaz69253 жыл бұрын
Thank you sir,best video!
@Prof.Dr.MuhammadNaveed3 жыл бұрын
welcome
@bloom.ss67 Жыл бұрын
Thankyou sir. I needed this so much.
@ahmedawan59094 жыл бұрын
Please response to these questions also thank you so much for providing information regarding I tasser
@ahmedawan59094 жыл бұрын
Can Secondary structure of protein contains favoured region allowed regions in Rampage?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes ofcourse
@ayeshamalik30304 жыл бұрын
when we click on Enxyme comission number than enzyme name is open what does it mean in I TASSER ?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
It actually describes the class family and other features of enzymes based on chemical reactions innvolved.
@ayeshamalik46794 жыл бұрын
Sir I have question the statistics used to compare results in I tasser are c score z score and TM score when both values are maximum protein is accurate and reliable ?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
normally we use C-Score for best predicted model identification. Yes, the good values mean good accuracy and reliability
@ayeshamalik30304 жыл бұрын
in I Tasser what is purpose of enzyme comission number?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
The enzyme commission number basically is a specific number allotted to each enzyme showing its class and family and other characteristics
@ahmedawan59094 жыл бұрын
We know that secondary structure folded to make tertiary structure then why in I tasser secondary structure dont show differences when folded to 3D protein model and same protein model in i tasser for different species? And in Rampage secondary structure is different in same 3D protein models of different species so values different why?
@ayeshamalik30304 жыл бұрын
Aik question tha what are characterstics of 3D protein models? Are the protein model different in different species? if difference than explain and if same then remove from the thesis? in this question i am asking that can i remove just figure of protein models according to question?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
you mention all protein models in text but in figure just put those have different 3 D models ok
@hassanmushtaq92343 жыл бұрын
Excellent sir❤
@Prof.Dr.MuhammadNaveed3 жыл бұрын
welcome
@ayeshamalik30304 жыл бұрын
If Protein models are same in different species through I TASSER then why RAMPAGE gives different values of favoured allowed and outlier region for same protein model in different species?
@ahmedawan59094 жыл бұрын
Can I tasser software be helpful to tell us differences in secondary structure of protein ?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes
@ahmedawan59094 жыл бұрын
Agar aik molecular marker sae protein structures construct krae by I tasser then protein models will be same for different species?
@ayeshamalik30304 жыл бұрын
Sir The Structure and Function of protein are characterstics of three D protein model?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
somehow, these are dependent on the structure
@ayeshamalik46794 жыл бұрын
It is necessary thar TM score and Z score are not mentioned in the statistics of I tasser
@ahmedawan59094 жыл бұрын
In I tasser secondary structure of protein is not changed and same 3D protein model for different species then suddenly in Rampage result how secondary structure of protein is changed for same 3D protein model in different species?
@ayeshamalik30303 жыл бұрын
in my data the C scores have less varaition and template homology PDB ID is same for different species and function is also same in different species Can i predict that protein models are structurally and functionally same in Different species?
@anisasehar22203 жыл бұрын
Can we use this scheme for mutated protein?? and can predict mutated protein function? of we need to make some changes.... one more thing is it possible to get the 3D structure of a specific protein DOmain???
@Prof.Dr.MuhammadNaveed3 жыл бұрын
yes can do
@decodingbio81144 жыл бұрын
Sir please improve sound quality in start and at end when you face the camera during demonstration it was good Well effort Sir
@Prof.Dr.MuhammadNaveed4 жыл бұрын
ok dear only in the last lecture faced this problem as mic off :) anyhow will check in next lecture.
@ayeshamalik30304 жыл бұрын
if protein models are same for different species in I TASSER? then why RAMPAGE gives different values of different species if protein models are same?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
RAMPAGE gives you the information about favored and unfavoured regions. That could be different in protein structures. There might be a difference in helix or turns or coils.
@ahmedawan59094 жыл бұрын
Why rampage gives different values for same protein model predicted by I tasser in different species?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
There might be difference in secondary structure
@ahmedawan59094 жыл бұрын
I tasser donot tell us differences in the secondary structure of protein and we assume protein model same due to no variation in C score and same template id but in rampage secondary structure of protein can be determined that contains favored allowed regions etc?
@ahmedawan59094 жыл бұрын
The ten different species have same protein models in I tasser then why same protein model for ten different species show different values in Rampage?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
There might be difference in secondary structure
@harisjan604711 ай бұрын
Sir my protein amino acid is very long and I taser is unable to run it , is there any alternative tool available to I taser which can generate structure?
@ayeshamalik30304 жыл бұрын
In RAMPAGE the values of favoured and nonfavoured regions were diffferent in same protein models for different species?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
could not understand your query. Pleaese elborate your query at aqibmirza67@gmail.com. Teaching assistant will reach you shortly
@fahimalamnobel47894 жыл бұрын
Sir in which format I-TASSER will give the result? Sir, will I get the result in educational mail or the institutional mail is a must for getting the result? Sir, I have another query. I want to use pymol for visualization may I use it in research purposes,i only found the edu pymol for free and it is not possible for use paid version, so can I use edu pymol for my research work or publication?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
dear result will be received in a web link in suggested email and when you click on it it will appear in web form. yes you can use pymol for research means
@fahimalamnobel47894 жыл бұрын
@@Prof.Dr.MuhammadNaveed but sir in pymol site there is a clear indication that edu pymol cannot be used for research and publication.It can only be used for learning? But i am confused what to do.Thats why i am asking this?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
@@fahimalamnobel4789 you can used
@fahimalamnobel47894 жыл бұрын
@@Prof.Dr.MuhammadNaveed Thank you very much, sir. Sir, I have another query that is when I use iedb for mhc1 binding,there I found the most probable allele for my selected epitopes. Further, I want to check the selected epitope and allele binding affinity(recheck or cross-check) by another online server, named EPISOPT(bio.med.ucm.es/episopt.html), recently I saw a paper, in there they recheck there epitope and allele binding affinity with that server. But the problem is I cannot enter into that link. Sir kindly help me I this regard or suggest me another server by which I can recheck my epitope and MHC 1(allele) binding affinity.
@ayeshamalik30304 жыл бұрын
different species C score template id same for all species A 0.91 B 0.90 C 0.93 D 0.96 E 0.91 F 0.93 G 0.94 H 0.89 I 0.94 J 0.92 This is i tasser results C score and template id same for different species . IS 3D Protein models same for different species according to values?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
send your query in detail at aqibmirza67@gmail.com. Teaching assistant to Dr. Muhammad Naveed will reach you shortly.
@ahmedawan59094 жыл бұрын
If C score has no more variation and template is same for all species then we predicted that protein models are structurally same for all species?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes
@ahmedawan59094 жыл бұрын
If protein models of different species have same function then we expect that protein models are same?
@ahmedawan59094 жыл бұрын
If protein models are same for different species in I Tasser then why in Rampage software protein models shows different values for different species?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
there might be difference in secondary structure of protein.
@ahmedawan59094 жыл бұрын
Can I tasser tells us about the differences in secondary structure of protein? How we can estimated the differences in secondary structure of protein in ITasser?
@ayeshamalik30304 жыл бұрын
Can RAMPAGE software that is used for validation of protein can be performed with Same protein model in different species?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes, can be
@ahmedawan59094 жыл бұрын
If protein models of different species have same function then protein model is same for different species ? Please explain this I am confused?
@ahmedawan59094 жыл бұрын
If protein model of different species have same function then we expect that protein models are same?
@Gautamkumar-om7im3 жыл бұрын
Can we use the predicted model by i tasser for docking purpose or we have further do something to the predicted model like, energy minimisation, Ramachandran plot prediction?sir please make a video on this topic.
@Prof.Dr.MuhammadNaveed3 жыл бұрын
sure and you can go with predicted model
@nidhijindal2210 ай бұрын
SIR WHY PART 2 IS NOT AVAILABLE?
@farihajavaid46532 жыл бұрын
Aoa sir...when im downloading model file does not open...kindly tell me which software is used to visualize these models or to read pdb files...
@Prof.Dr.MuhammadNaveed2 жыл бұрын
PyMol or discovery studio
@farazkhan87134 жыл бұрын
Sir, please make a video about molecular modelling of protein which lies in twilight zone using abintio method.
@Prof.Dr.MuhammadNaveed4 жыл бұрын
sure, but I-TASER cited mostly in articles and made video on it
@deepasreek5172 Жыл бұрын
Sir, the C-score value for my protein model1 was -4. Is it okay to use that model for further studies?
@ayeshamalik30304 жыл бұрын
if we construct protein structures with only one molecular marker by I TASSER then protein structures will be same in different species?
@ayeshamalik30304 жыл бұрын
if C score of different species are 0.91, 0.90, 0.93,0.96, 091,0.93, 0.94, 0.89, 0.94 and 0.92 and template id is same for all species then protein model will be same or different ? please explain this
@Prof.Dr.MuhammadNaveed4 жыл бұрын
it depends upon the secondary structure
@ahmedawan59094 жыл бұрын
Is it possible that I tasser developed same protein models for different species?
@ayeshamalik30304 жыл бұрын
Can I Tasser tells about the Characterstics of 3D protein model? which part of I TASSER describes the 3D protein model Characterstics?
@zainiiBee3 жыл бұрын
My ques is I used ITASSEr and TrRosetta both. Both showed diff models Should i go for ITASser ? The 1st predicted structure in ITASSEr needs to be validated through Ramachandrn plot? If so then my 1st predicted model gives allowed residues of 85%. What should i do?? Please guide . I need a complete guide as i am stuck
@Prof.Dr.MuhammadNaveed3 жыл бұрын
go with I-Taser and refine score by glaxyrefine
@zainiiBee3 жыл бұрын
@@Prof.Dr.MuhammadNaveed i did it. After refining when i chek again the quality was now down from 82% before refining to 69% after refining. Any suggestion please sir???
@ayeshamalik30304 жыл бұрын
Agar secondary structure of protein mae difference ho teo Rampage gives different values for same protein model in different species predicted by I TASSER?
@chiragsoni67704 жыл бұрын
Sir is everytime possible we will get top five models predicted by I-TASSER of query seq. ? Because I got only one model
@Prof.Dr.MuhammadNaveed4 жыл бұрын
most of time possible to have 5 models but when sequence is unique or have less homology then possible to have 1 or 2 but if score is ok then you may use this
@chiragsoni67704 жыл бұрын
@@Prof.Dr.MuhammadNaveed I got C-score value of my predicted final model is 0.61 and got TM-score value that is 0.949 and Coverage of alignment is 1.000 to related PDB structure. So is my structure good or bad ? Can I use it for further protein-ligand docking process ?
@ahmedawan59094 жыл бұрын
The difference in secondary structure of protein could be observed in Rampage only in the form of different values in favored allowed region and outlier region?
@simonparmar24584 жыл бұрын
Sir, can you plz make a video on molecular docking.?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
kzbin.info/www/bejne/rl7ZqoB_qKihiZI
@ayeshamalik30304 жыл бұрын
if proteins models are same for different species in I-TASSER then we can validate the protein model by RAMPAGE if protein models are same?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes u have to validate and refine
@ayeshamalik30304 жыл бұрын
So For same protein model in different species and different protein models in Different species the values of favoured and nonfavoured region is always different?
@ahmedawan59094 жыл бұрын
Agar rampage values different show ho rhae hae in different species it means protein model are different in I tasser?
@ahmedawan59094 жыл бұрын
If protein models are same in I tasser for different species then in Rampage the values of favored nonfavoured region will not show too much difference?
@ayeshamalik30304 жыл бұрын
Can we estimate that protein models are different or same in different species in I- TASSER with he help of C score and template homology ID? IF C score has no variation and template id is same then protein models are same for different species?
@ahmedawan59094 жыл бұрын
My question is that if we have same protein models for different species in I tasser then validation by rampage give same values of favoured allowed regions in different species?
@ayeshamalik46794 жыл бұрын
What statistics are used in the ramachandran plot analysis is allowed region outlier region and favoured region are statistical ratios?
@ayeshamalik30304 жыл бұрын
In my result the C score of ten diffferent species are 0.91,0.90, 0.93, 0.96,0.91,0.93,0.91,0.96,0.92,0.89 and template model is cryo -EM strcutre of stringent respnose factor REIA bound to ErmCL- Stallled ribosome complex in all ten species is protein model same for ten different species?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes
@hitkarshkushwaha24343 жыл бұрын
👌👌👌
@Prof.Dr.MuhammadNaveed3 жыл бұрын
Pleasures and welcome dear
@ayeshamalik46794 жыл бұрын
The value of Z score 3.63 is good value?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
depends upon the comparison with other values. If it is the highest, than it is.
@ayeshamalik30304 жыл бұрын
if the protein models have no difference in different species by I TASSER? then it is possible to be validated by RAMPAGE?
@ayeshamalik46794 жыл бұрын
If structure and function is Same and cellular component is different than 3D protein model will be same ?
@ayeshamalik30304 жыл бұрын
if protein models are same in different species through I- TASSSER can we validate the same protein models of different species through RAMPAGE?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes you can validate
@hassanmushtaq92343 жыл бұрын
Sir jo proteins bre hte hain more than 1500 ... uski prediction kese krain gy?
@Prof.Dr.MuhammadNaveed3 жыл бұрын
then need to use a manual method of modeling as by using MODELLER
@ayeshamalik30304 жыл бұрын
Sir agar protein models same ho for different species in I TASSER then after validation by RAMPAGE there is no much difference in the values of Favoured allowed region ?
@ahmedawan59093 жыл бұрын
Sir agar favoured region and allowed region and outlier region kae values mae itna difference nhe Ara ha it means protein model are same for different species? The favoured regions values are 88 87 85 84 83 81 and allowed region values are 7 8 9 10 11 and disallowed have 0 0 0 4 2 etc? Is protein models almost same in different species?
@Prof.Dr.MuhammadNaveed3 жыл бұрын
yes same
@ahmedawan59093 жыл бұрын
Sir these values also have no more difference?
@Prof.Dr.MuhammadNaveed3 жыл бұрын
@@ahmedawan5909 same
@ahmedawan59093 жыл бұрын
Sir merae data favoured allowed region mae values mae itna difference nhe hae na we considered that no variation ?
@ayeshamalik46794 жыл бұрын
I have also question and commented on the clustal W and phylogenetics lecture please reply to this question also
@ahmedawan59094 жыл бұрын
Secondary structure of protein kae andar jo differences aataee hae wo just rampage mae pta chalta hae KIA?
@ayeshamalik46794 жыл бұрын
Is it possible that tasser develop same model for different species ?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes possible if query sequence have less variations
@ayeshamalik30304 жыл бұрын
In Callicarpa and Tectona species i have noticed from the result that in Callicarpa the cellular component is cytosol while in Tectona the cellular component is chloroplast while rest biological and molecular function same so we can say that different model due to minute sequence variation?
@ahmedawan59094 жыл бұрын
Agar hum same protein models ko validate krae gaieee rampagae sae teo they always give same values of favoured allowed regions
@Prof.Dr.MuhammadNaveed4 жыл бұрын
you are telling something or asking?
@ahmedawan59094 жыл бұрын
Asking
@Prof.Dr.MuhammadNaveed4 жыл бұрын
@@ahmedawan5909 contct us through phone so we may guide you properly
@ahmedawan59094 жыл бұрын
Sir ap mujay email per bta daiaee my phone is not working properly
@ayeshamalik46794 жыл бұрын
Sir statistics of I tasser mae.Kia mention kr sakataee just C score?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
No each score in I-Tasser is statistics-based. Tm Score, Z-Score, C-Score
@ahmedawan59094 жыл бұрын
How we can estimated that protein model is same or different in I tasser for different species what's the reason?
@ahmedawan59094 жыл бұрын
How can be estimated that protein models for different species in I tasser are different or same in different species?
@ahmedawan59094 жыл бұрын
Can i tasser and Rampage software both can tell us differences in the Secondary structure of protein?
@ayeshamalik46794 жыл бұрын
I am confuse which statistics used in ramachandran plots by rampage?
@ahmedawan59094 жыл бұрын
If the template is same for all species in I tasser then protein model will be same?
@fahimalamnobel47894 жыл бұрын
Sir plz make a video on Ramachandran plot and analyze in RAMPAGE and Molecular dynamics after protein-ligand docking to analyze the binding quality in AMBER software, or another well-known software.
@Prof.Dr.MuhammadNaveed4 жыл бұрын
sure dear will do thanks
@fahimalamnobel47894 жыл бұрын
@@Prof.Dr.MuhammadNaveed Sir another problem i am facing in 3D modeling .Sir i have n't any educaional mail.What should i do then??
@Prof.Dr.MuhammadNaveed4 жыл бұрын
@@fahimalamnobel4789 dear use email ID any of your friend as only results link will be send on that email so ask any teacher or friend otherway use MODELLER offline tool
@fahimalamnobel47894 жыл бұрын
@@Prof.Dr.MuhammadNaveed Sir MODELLER tool can be download by free from online?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
Dear@@fahimalamnobel4789, Yes it can be.
@ayeshamalik46794 жыл бұрын
If the Z score is 2, 3, 4,8,9 for different species then we said that score is best?
@ayeshamalik30304 жыл бұрын
Can we validate the same protein models in different species through RAMPAGE?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes
@sonamgupta10622 жыл бұрын
sir agr 3D str. mai Z score less than 1 aa rha ho toh kya krna cahiye
@sarakhazeema66293 жыл бұрын
How to predict the disease causing mutation of a protein through I-TASSER sir? Please answer
@Prof.Dr.MuhammadNaveed3 жыл бұрын
not by I-Tasser but can compare structures
@syedaanam17323 жыл бұрын
Which tool/software to be used for the visualization of protein structure downloaded as pdb file?
@Prof.Dr.MuhammadNaveed3 жыл бұрын
Discovery studio or JMol
@ahmedawan59094 жыл бұрын
Is it possible that I tasser develops no difference in protein model for different species?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
Already replied many times
@ahmedawan59094 жыл бұрын
Agar rbcl protein sae all structures construct Krae by i tasser in different species then protein model will be different or same?
@ayeshamalik46794 жыл бұрын
The change in the cellular component of 3D protein model but function same then we predict protein model are different?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
might be
@fahimalamnobel47894 жыл бұрын
Sir, I have done all the things perfectly. Alhamdulillah. But sir I am now a little bit confused about the structure refinement and energy minimization. Is the two things do the same work? I am also confused that which work i performed first, energy minimization or refinement??
@Prof.Dr.MuhammadNaveed4 жыл бұрын
Both different as structure refinement relevant to structure validation and energy minimization is related to molecule interaction
@fahimalamnobel47894 жыл бұрын
@@Prof.Dr.MuhammadNaveed Sir when i modeled my protein structure i validate it through ramachandran plot,so i get 88% in favoured region but sir after i refined my structure by 3d refine server and then energy minimization is done . After that i again check it by ramachandran plot.But after refinement and energy minimization my proteins favoured region get decreased in 85%.What is the region of that. ?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
@@fahimalamnobel4789 so that means other 15 % is now in unfavoured region
@fahimalamnobel47894 жыл бұрын
@@Prof.Dr.MuhammadNaveed Sorry sir 83.1%,so the structure is valid in that percentage?? Another think is written in procheck server that is "You have no END tag. You must have 1" .I dont understand this sentence. The sentence shows after refinement and energy minimization of my structure. And in some structure this sentence is also written before and after the refinement and energy minimization of the protein.
@Prof.Dr.MuhammadNaveed4 жыл бұрын
@@fahimalamnobel4789 yes if it is the standard mentioned in the tool page
@ayeshamalik30304 жыл бұрын
Favored region Allowed region Outlier region 88 8 2 81 10 7 85 9 4 87 9 2 85 13 0 85 13 0 88 8 2 84 13 1 83 13 2 84 11 3 This is result of Rampage validation of same protein model for different species is values different in Rampage results when we estimate that protein models are same for different species?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
Your query is not clear. Please elaborate your query art aqibmirza67@gmail.com. Teaching assistant to Dr. Muhammad Naveed will reach you shortly.
@ahmedawan59093 жыл бұрын
Please answer to this question it is urgent question thanks
@zainabhasan10204 жыл бұрын
through which software can we download these models
@Prof.Dr.MuhammadNaveed4 жыл бұрын
you can generate these models using I-Tasser
@Prof.Dr.MuhammadNaveed4 жыл бұрын
install Discover studio or JMol or PyMol for downloading and visualization of Models
@ayeshamalik30304 жыл бұрын
SIr i want to ask that Callicarpa species has 0.91 C score and Tectona has 0.90 so is the different model is different for these two species? if we estimat e that Different C score leads to different 3D protein model
@Prof.Dr.MuhammadNaveed4 жыл бұрын
their score not much different so model might also same
@ayeshamalik30304 жыл бұрын
In my data active site is different in different species then model will be different?
@ahmedawan59094 жыл бұрын
Is it possible that same protein models for different species in I tasser gives different values of favoured allowed region in rampage what's the reason?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
Yes possible as might have difference in secondary structure
@ahmedawan59094 жыл бұрын
In I tasser if amino acid sequence not changed then structure of 3D protein models is also same?
@Prof.Dr.MuhammadNaveed4 жыл бұрын
yes
@ahmedawan59094 жыл бұрын
Agar aik hae protein sae models construct krae for different species then protein model will be same or different?
@ahmedawan59094 жыл бұрын
If template and function of protein models are same in different species then we predicted that protein models are same in different species?
@ahmedawan59094 жыл бұрын
If protein models are same for different species in I tasser then in Rampage we validate the protein model of all species?