IgG4 related disease a challenge in the diagnosis

Short description
This webinar focused on the challenges of diagnosing IgG4-related disease, including the epidemiological features that may help suspect IgG4-related disease, the most common clinical presentations, suggestive laboratory abnormalities, typical pathology, and imaging features.
Moreover, the webinar covered the disease phenotypes and recently published classification criteria. The final part of the webinar was devoted to updates on therapeutic approaches.
All resources and more info about IgG4-RDs can be found here: reconnet.ern-net.eu/disease-igg4/
Speakers
- Dr. Della Torre earned his Medical Degree, a Board Certification in Allergy and Clinical Immunology, and a PhD in Basic and Applied Immunology at Vita-Salute San Raffaele University in Milan (Italy). Dr. Della Torre worked for 3 years at the Rheumatology Unit of the Massachusetts General Hospital, at the Ragon Institute of MGH, at MIT, and at Harvard in Boston (US). In 2018, Dr. Della Torre returned to Italy and established his lab at San Raffale Hospital (Milan, Italy). Currentlly, Dr. Della Torre is Assistant Professor of Rheumatology at Vita-Salute San Raffaele University and Senior Rheumatology Consultant at San Raffaele Hospital. Dr. Della Torre authored more than 100 scientific publications and achieved prestigious awards such as the Career Research Grant Award from the Foundation for Research in Rheumatology (FOREUM). Dr. Della Torre contributed to the characterization of IgG4-related disease and is currently coordinating the IgG4-related disease Working Group for ERN-ReCONNET.
- Prof. Tobias Alexander, CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (Germany).

[@nanaprn7809]

Have you noticed any increase in IgG4 related disease associated with mRNA vaccines???

[@mikeg9367]

kzbin.info/www/bejne/l4PWmmeOeqySfKM Yes, and watch the above video, the guy explains data on how MRNA vaccines increase IGG4 by a lot.

[@markofday]

Yes

[@BernerVRshow]

Mer egonemics have a video about this yesterday.

[@ContessaThe3rd]

Dr. M. Raszek (Merogenomics) now has 9 very informative you tube (& other) videos where he summarizes recent peer-reviwed publications of IgG4 issues in folks who took mRNA (spike protein) vaccines. The effects are most marked in those who had not previously been infected with Sars Cov 2. Infection with Sars Cov 2 actually was somewhat protective - perhaps this can help elucidate the MOA of non-spike protein-mRNA-related IgG4 disease??? I beleive there will be aflurry of research activity now this is being reported widely.

[@gracewhite1601]

Its all over the internet now

[@bam4018]

I learned a lot about IGG4. Good research!

[@minicraftslearnplay3509]

Hi is your igg4 elevated?

[@myangelwings45]

The new research coming out from the CV vaccines are showing unusual increases in IGg4 with multiple vaccinations. There has also been an increase in “rare” cancers of the bile ducts and liver/pancreas. My sister just died from this. She was fully vaccinated and boosted 5 in total. Only lived 5 months. Was healthy until this diagnosis. I now know 5 people in my town in Canada who have or have died from this very rare and agressive form of cancer. Coincidences I don’t think so.

[@BernerVRshow]

Mer e go menics have a video about this yeasterday I think.

[@myangelwings45]

@@BernerVRshow yes I follow him. Very bright person. Knows his stuff.

[@BernerVRshow]

I am so sorry for your loss of your sister.

[@myangelwings45]

@@BernerVRshow thanks.

[@rossanajoubert4881]

Thank you for this information 🙏

[@Itsme-jv4cd]

Can IgG4 be associated with other fibrotic diseases like amyloidosis ,other than AA Amyloidosis?

[@ellenbruckermarshall4179]

Mine started after 10 years of untreated Lyme disease and co-infections.

[@rcbillg]

Did it go down after treatment?

[@user-sn6ph7je2h]

Can high dose of Vit. D3 can replace presnisone?

[@venomx4093]

No

[@marymagnuson5191]

Bu no one considers parasites. I had huge IgE for decades. Finally got a diagnosis of Strongyloids. Treated and cured. Miracle.

[@dreadedhalo]

Whats the details of your treatment? What medicine, Docis, length of time on and off and monitoring.

[@marymagnuson5191]

@@dreadedhaloIvermectin 12 mg once a day + albendazole 400 mg 2x/day for 30 days. Then same dose 2 days a month for 12 months. You will need to talk to a Dr. In Africa or India. US won’t talk to you.

[@manisharai8395]

I m suffering from IgG4 disease from 8 years 😢 how can it be treated for lifetime

[@minicraftslearnplay3509]

Hi . How big is your igg4? Any symptoms? Did you had steroids?

[@backalleygaming7096]

wouldn't it be better for patients to go straight to monoclonal antibodies first before going to steroids? considering how steroids isn't a long term treatment while patients relapse any ways. plus that steroids even in a few weeks of exposure can reduce cortisol levels permanently in many patients.

[@socrates8495]

All that funding of money and no cures - corruption

[@justinduffer9500]

They have to be able to make lots of money and damage your health during the process. I'm sure they working on a " cure " now that it's much, much more common thanks to the " vaccines ".

[@commenter4139]

Discovered 20 years ago or invented 20 years ago?

[@richardcooley9730]

From what I have read it appears more like a slow lightbulb moment of realisation, one that acknowledges previously identified conditions have this in common. It was first defined as such 20 years ago although it was first suggested about ten years before. To this day, in Europe at least you will be treated by the specialist relative to your presentation and, whilst this is a practical working solution it means nobody appears to be driving research. It is Japan and US where most work appears to be undertaken.

[@user-qt7ud1cl7b]

My father died 40 years ago when they said he died from cancer know he was a Eli Lilly laboratory researcher that worked in the medicine medical formulator department that actually tests Eli Lilly medicine on animals primates chimpanzees canine dogs the top two level departments in Eli Lily

[@joannrobinson8830]

These good Dr's are doing their best to help people with this disease. I get it. If people would obey God these diseases would not be chasing them down, says so in old testament.