Рет қаралды 15,903
GROUP NAME: Ammuno-therapy (group 25)
Group members:
- Gavin Huangfu
- Ella Scacchia
- Amy Stiklius
- Pauline Deng
We will use an animation to discuss immune editing, with emphasis on the role of the immune system in regulating tumour cells. We will be focusing on the three E’s - elimination, equilibrium and escape (and what can contribute to each of these stages). We will also highlight the type of immune cells that play a role in these processes and how they recognise tumour cells.
References:
Chung, D 2015., Immunology Cartoon Project. Available from: www.daisychung..... 1 October 2015.
Dunn, GP et al. 2002. Cancer immunoediting: from immunosurveillance to tumor escape. Nature Immunology. 3: 991-998.
Dunn, GP Old, LJ & Schreiber, RD. 2004. The three Es of cancer immunoediting. Annual Review of Immunology. 22: 329-360
Mapara, MY. 2004. Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. Journal of Clinical Oncology. 22: 1136-51.
Smyth, MJ et al. 2005. Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer. Journal of Experimental Medicine. 202:583-88
Smyth, MJ et al. 2001. A fresh look at tumor immunosurveillance and immunotherapy. Nature Immunology. 2: 293-299.