Inflammation 4, Inflammatory Mediators

[@farahmansour326]

Thank you so much !! your lectures are more beneficial than 2 hours from setting in hall and understanding nothing .. God bless you !

[@jennyhancock3474]

I love the pace of the information delivery, makes it really easy to understand! Thank you!

[@teodoramolnar7146]

This was very helpful! I didn`t even realise how little I understood about inflamation until I saw this. Thank you very much!!

[@brodericksmith01]

You are a wonderful teacher! May God continue to bless you.

[@michaelkashina6864]

God really bless you. I've no words only have to thank God for this blessing over you.

[@tapanshah2900]

Absolutely brilliant.You are one in a million.Thank you for your videos.Much appreciated.

[@albertayohuno9929]

You are a wonderful teacher. Very patient and broke this down in simple terms. The illustration was helpful as well. Thank you!

[@EmilieRosanvallon]

Thank you SO MUCH. Such an excellent teacher. I've been looking everywhere to really understand inflammation and SIRS! Thank you!

[@meganrystad3341]

great videos on immunity.. They are helping me in my Pathophysiology class right now .. Thank you!

[@ShhhHhhhz]

i suffer from atopic dermatitis and i have to take immunosuppressant drug like ciclosporin to negate inflammation in order to stop the itch and scratch cycle. You made me understand the use of Prednisone for temporary relief. Thank you, i feel truly enlightened by your lessons

[@alemutegene1870]

A VERY INTERESTING LECTURE Dr JOHN C Live long

[@enochbrown8178]

Simply outstanding!!!

[@carolclark5776]

You r the best most rxcellent easiily followed teacher

[@kulejoseph8766]

Thank u from Uganda, we are using technology in resourceful way

[@JesusIvanGarcia]

Thank you! Very easy to understand lecture! You helped me out a lot

[@babitera1]

God bless you Dr. Your videos are really helpful!!!!!

[@vama-mental-health]

Thank you very much DR

[@maceywalker266]

Very helpful. I appreciate the repetitive nature of your lecture style. Wonderful to have material presented in a clear format. Unfortunately my current pathophysiology professor is all over the place...

[@joannakosinska4480]

they r very VERY helpfull!! for every medical student

[@abdulazizmohammed2050]

danke schön !!

[@Imhotep25296]

Thank you so much!

[@moniqueleroux5950]

Excellent!

[@anthonykaralekas6275]

You should incorporate some of the very recent studies on Bradykinin (ACE2 dysregulation) into your COVID videos!

[@arunam7669]

please detailed description about bradykinin

[@chetennorbu849]

great help sir!!

[@kabojaalex3649]

Dr. Thanks for such wonderful lectures please

[@kshamtaagrawal6352]

Tqq soo much doctor 😊😊😊😊

[@alial-dujaili8633]

Extremely helpful, thanks a'lot

[@Sali_Levi]

Very clear thank you :)

[@katadavid5231]

Thank you!

[@flynner1997]

this really helped thanks

[@ankitachoudhury3222]

AMAZING :)

[@thomasmbeba5690]

Dr JC any new lectures for 2017

[@OJASVIVYAS]

Please upload more ..Proffessor..do u teach Microbiology too!!!!

[@histolab1193]

Thank really you are wonderful prof excellent lecture im from Sudan

[@martinmcg6543]

love it.

[@jacobvandijk6525]

After 12:58: I don't agree with your view on the relationship between basophils and mastcells. In my opinion they have a different lineage. Yes, they are look-alikes, but they have different ''parents". Thanks for sharing your knowledge!

[@Campbellteaching]

What does Grey's Anatomy say on the topic? I usually use this to give definitive information.

[@jacobvandijk6525]

@@Campbellteaching First of all, thanks for your reaction. This is from "Gray's Anatomy International Edition: The Anatomical Basis of Clinical Practice": Despite these similarities, basophils and mast cells develop as separate lineages in the myeloid series, from haemopoetic stem cells in the bone marrow.

[@Campbellteaching]

Interesting, so the mast cells do not derive from basophils, well spotted. You also correctly use the evidence from Grey's, we must always be evidence based. Given that this is the case, I wonder how they get into the tissues, they must travel as a form of leucocyte in the blood before migrating from the capillaries. May be this only happens in early life and they carry on dividing once the progenitor cells are in the tissues? @@jacobvandijk6525

[@jacobvandijk6525]

@@Campbellteaching I'm intrested in blood cells and the immune system because last month I was diagnosed with sarcoidosis in the lungs. Your videos made a lot of things very clear to me. Thanks! I think the immune system is a fascinating thing. Yes, you probably will say that the complete human body is fascinating ;-) I hope to answer your question soon.

[@jacobvandijk6525]

@@Campbellteaching The following link tells you more about the migration of mast cells. I would start with reading the conclusion. www.ncbi.nlm.nih.gov/pmc/articles/PMC1490026/

[@ahmedmohammad4637]

in arabic شكرااا جزيلا

[@cecilien9407]

Is it correct that the exact mechanism behind the anti-inflammatory effect of NSAIDS is unknown?

[@Campbellteaching]

No, its known, they inhibit cyclo-oxygenase so prevent the formation of pro-inflammatory prostaglandins.

[@cecilien9407]

@@Campbellteaching Thanks!! Is there any type of pain medication that in addition to relieving the pain also has an unknown anti-inflammatory effect? I keep thinking there is one, but I can´t remember where I read this. Thanks for your patience.

[@s.m.shahnewaz6880]

Thank you so much sir for your excellent lectures.I am Dr.Shahnewaz from Bangladesh.Sir is there any relation between inflamatory mediators and melanin?why PIH happens.Thank you. with Regards Shahnewaz

[@ankitaranisinhatheinnovato6980]

awesomse

[@jamesthomas1753]

thanks I learned a lot, but you don't need much imflamitation, I get better results by avoiding any imflamation,

[@jkludz]

If steroids inhibit phospholipase A, what happens when steroid treatment stops? Is there a buildup of lipid in the tissue that would result in an increased inflammatory response, or is there another degradation pathway that doesn't lead to inflammation?

[@mohsenahrari6953]

phospholipase A2 will only work on phospholipids let loose by the injured cells. if there is no injured cells or dead cells then there is no phospholipids or phospholipases to react. therefore no inflammation. hence corticosteroids are used when there is cell injury or death and inflammation.

[@avishlei]

Very helpful indeed, but the correct etymology of arachidonic derives from the latin word for peanuts - arachis!

[@aboazzam7988]

Mr, at 13:37, you said that mast cell is a basophil.. I have searched quickely and I read that it thought to be.. but the fact is each one develops from diffrent hematopoietic lineages.

[@Campbellteaching]

Are you sure - what does greys Anatomy say?

[@kulejoseph8766]

Actually most resources describe mast cells to be basophils in tissues, I wish u give us the source of information and we look at it

[@asharp2553]

Which nursing school in England Dr Campbell teach? Thank you.

[@skcham2178]

Please anyone about the general features of inflammation in children and senile age.

[@anjaeloise7600]

Too general, what about MIF, PAR-2, tryptase, SCF...?

[@govindamparamanandam1]

Love the content but had difficult time focussing due to the annoying sound of the sharpie on the board.

[@marysmith6229]

2021..

[@dr.ahzam_official]

the noise was irritating when you write or that sheet...otherwise lecture was quite worth...

[@saja4887]

Exactly 💔💔

[@QueenofCool]

Doctor, I just want to ask why you are angry? Jk. You teach stuff in a very simple manner yet so efficient. Thank you so much!

[@Campbellteaching]

Sorry, no anger intended.

[@kausarsahebzda6719]

These mark s very irritating

[@kausarsahebzda6719]

I mean markers