InterPro | How To Know About Domain In Protein Structure & Their Function in 5 mins | Bioinformatics

[@bioinfoxpert]

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[@mehwishahsan2194]

You make things so much easier to learn. Thank you for the efforts.

[@bioinfoxpert]

You're very welcome!

[@shanzaakhtar5481]

Appreciated 👌

[@bioinfoxpert]

Happy to help

[@curiousways7827]

Tysm sir.. very helpful tutorial

[@bioinfoxpert]

So nice of you

[@shichengguo8064]

Can we only select to use Pfam only in interprot?

[@bioinfoxpert]

Yes you can use Pfam. It will be totally fine.

[@zainiiBee]

i am using interpro, but my results arent like yours, it shows the entry matches to Domain of Unknown Function and in that Predicted 3 domains, cytoplasmic, transmembrane and non-cytoplasmic, all with no siginificant pdb match

[@bioinfoxpert]

If you see on your right hand side then there will be some number like IP0231098. Click on them. It will take you to the specific domain section. There will be structures of domains as well

[@zainiiBee]

@@bioinfoxpert yeah i did that too. No structures or any homolog to that domain as well Since i m working on novel protein with no annotations so its different for me n thats where i am stuck n tired n confused..

[@bioinfoxpert]

Yes you are right. It happens sometime

[@carolinej.3523]

Hello sir, on my result page, there is predictions entry.. what is that?

[@bioinfoxpert]

You are very right but in case we do not hv 3D structure in PDB then then alpha fold is a good option

[@bioinfoxpert]

Interpro let you the domain which are validated in literature. Along with it based on sequence homolgy it also predicts some possible domain in your sequence. These are just predictions.

[@nehasharma7912]

How to know the motifs functions?

[@bioinfoxpert]

Dear you can click on number present along the motifs. When you will click on them then the details of motif will come infront of you.

[@malihafatima6921]

There is no domain...only predictions...how can i draw pdb and highlight domains with name in form of diagram as i have to paste it in thesis

[@bioinfoxpert]

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[@arjunhere19]

👍👍👍👍

[@bioinfoxpert]

Thanks for your thumbs up. Hopefully you will like our other videos as well

[@bioinfoxpert]

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