Introduction to bioreactors

This video gives a short introduction to bioreactors. As more chemical engineers are employed by the pharmaceutical industry, it is important to implement more "bio" content in the curriculum and thereby increase employability.
Bioreactors are different from traditional chemical reactors; because the catalyst used in there is "alive"; therefore, it is important to keep strict control over the conditions in the reactor. An overview of a traditional stirred tank bioreactor is provided, in addition to discussing some of the key design challenges.

[@johnappleyard4123]

Great explanation!

[@MarloesPeeters]

Glad you think so! We have many more videos in this playlist and would like to expand on the bioreactor section; ideas are welcome.

[@hernan2907]

Thank you very much for your video. Very interesting.

[@MarloesPeeters]

So nice of you to say that - hope you like the other videos in the playlist Bioreactors :)

[@hernan2907]

@@MarloesPeeters I will look at them and I am sure I will like them, very professional.

[@akamal92]

Very interesting

[@MarloesPeeters]

Glad you think so!

[@gutsandglory7507]

Thank you for this video, Prof Peeters. I am working on bioreactor design for my Master's research, I am into more of plant tissue culture and solid waste of agricultural origin to enable extraction of valuable materials like secondary metabolites through the process of valorization. I would like to have your guide pls. If you won't mind can I send you a mail with the details of my thought, I know I must be wrong somewhere? Thank you.

[@MarloesPeeters]

Thanks for your response! You can always send me an email to get some thoughts although I have to say plant tissue culture is not my expertise (although I would like to hear more about it)

[@munibabdo4740]

Thank you

[@MarloesPeeters]

Thank you! We have another video out on bioreactors which might be of interest (on mixing, agitation, and shear): kzbin.info/www/bejne/hoa5fmuAr76fobM

[@tylerreynolds9013]

great video! i do have a question. im writing a book and i need to know if there a bioreactor that produces clean energy with any kind of biowaste. it doesnt have to be clean or be able to use anything as fuel, its just prefered. also can i use you as a source

[@MarloesPeeters]

Thanks! What do you mean by clean energy? Are you thinking about for instance biogas which is produced from waste?

[@tylerreynolds9013]

thanks for replying so fast! im looking for energy that releases gas that isnt greenhouse gas and isnt harmful. again, the greenhouse gas part is just prefered beacause its still carbon neutral. im also told i should tell you im 11.

[@calamitysargo8017]

Nice video! Already subscribed and go checking the rest of them! Thanks for the work!

[@MarloesPeeters]

Thanks for subscribing! We are certainly planning to make more videos on bioreactors, so keep an eye out for new ones (or let us know what you are interested in)

[@BernhardRieder1]

Do you have more information about a Bioreactor specifically for culturing skin tissue?

[@MarloesPeeters]

I know little about this but I have some colleagues who worked on this topic. An example can be found here: www.sciencedirect.com/science/article/abs/pii/S0925400519308524

[@openyard]

Good educational video. The sound seems like you are far from the microphone. I would suggest a better mic maybe one that you can attach to your shoulder or neck.

[@MarloesPeeters]

Thanks for the tips! I used a different microphone/ camera back then. I hope the sound is better in the second bioreactor series

[@khai1947]

srsly tq

[@lschuh8316]

Good Information!!! Nice videos to learn, Thank you! Do you have in mind to make als a video about solid state fermentation?

[@MarloesPeeters]

Not in mind but I think it is an excellent suggestion! Definitely something I can look into of the next couple of weeks (we do have one video on fermentation in the other bioreactors playlist)

[@lschuh8316]

​@@MarloesPeeters Thanks for your rapid response... May be you may comment on a question: on Lab-level a lot of fermenter-research relies ONE single stem of a bactrium to produce a specific compound. Whet is your opinion about scaling fermenter up to industrial scale and the danger that this specific bactrium is overgrown by other bacteria being "stronger" and more abundant. What is done to prevent this? (from another perspective: this can become a problem e.g. in waste water denitrification)... Regards Lothar from Heidelberg

[@MarloesPeeters]

@@lschuh8316 Very good question! I don't have a lot of experience in this area but this is a very valid concern for long term continuous operations where a "mutant" can take over. So monitoring is one way of checking for this and the other one is identifying what is the best residence time. There might be other chemicals methods of suppressing bacterium growth but I am not sure how this would work

[@sayangarai927]

Can you suggest a good book for Industrial microbiology??

[@MarloesPeeters]

Apologies for the late response. I have used Bioenineering principles from Pauline Doran for several videos

[@sayangarai927]

@@MarloesPeeters thanks a lot ma'am 🙏🙏 For your valuable reply 😊😊

[@abunawenow8696]

I’m still asking myself why I need to learn this as a SOFTWARE Engineering student 🤦🏾

[@hutaotao5569]

Ayy, maybe you can program the Simens Simatic S7-1500 for the bioreactor.

[@MarloesPeeters]

Modeling of bioreactor is very important so we need help from software engineers there. Also for the control of bioreactors, you might need tools for interpretation of big data

[@ivankayadavofficial]

Sorry to say, but you need to know many many thing about Bioreactor.