Iron Absorption Explained

[@karahunter44]

Helped me understand a 4 hour lecture in less than 20 minutes. Thank you, I will be sharing with fellow study partners.

[@tomsflaherty]

Really fantastically explained. Thank you very much for this. I'm a doctor and this will be very useful for med students.

[@SonuNigamUnofficial]

You are amazing ...sir KZbin has become my Library and study hall beacause of you like people

[@nwakolpo]

Thank you so much for the lecture! It appears strange to me why a lot of MDs still believe you will get anemia if you are vegetarian or vegan since there won't be heme iron sources in your diet.

[@raymondoseiboampong1945]

Wow...How come I've never heard about you. This is awesome. My plan was just to watch but I ended up subscribing 😂

[@Legomed]

That's great! Welcome aboard

[@MannyFreshMKS]

Thank you! Helped me with my hematology final so much

[@WISDOM-AdikwuMarthaOka]

Amazing presentation👏👏

[@C06548172]

Another excellent video, thanks!

[@emanuelisamky4895]

clearly explained thanks i gain a lot from this video!!!!

[@Legomed]

Thanks Emanueli! I am glad you enjoyed it. Best wishes, Vernon Louw

[@WATCHINGTHEWATCHERS999]

Great explanation as always! May I ask a question?

[@patiencefranklin4157]

Very informative

[@smolkovi]

Hello, thank you for your video! I have question about iron dissociation from iron metal bond lattice. My colleague thinks it is not possible to have iron in an ionic form because bonds between iron atoms are very strong and its need add much energy (melting point is 1538 C). Than he thinks if iron reacts for example with acid it stay in lattice form with binding anions of acid (for iron its 9 atoms in cubic pack with one atom in center). In biology he believes iron have the same form of 9 pack atoms of iron. How can I explain him that's not right? PS Sorry for my bad english

[@نوراحمد-ك6س1ه]

Excellent Thank You

[@viosno]

I remember FeRRIC form as TeRRIffiC Three - Fe3+ :). As my boy was terrific only when he was 3 as opposed to 2 ;)

[@xDomglmao]

I remember it like this: Heme = carries O2 = Fe2+ = ferrous (the "o" for "oxygen") Nonheme = does not carry O2 = no 2 involved = Fe3+ and also: no O2 involved = no "o" = ferric (no "o" in ferric)

[@mohammedgaber1978]

That is awesome ! You helped me so much , Thanks

[@jaimelancaster5277]

When Fe2+ is converted to Fe3+ by ferroportin/ceruloplasmin what happens with the electrons? Do they form ROS?

[@Ellascinder]

hi! doesn't the ferritin in the duodenal cells bind to ferric?

[@fasttimes953]

What the thresh hold of ferritin levels?

[@ginxtac18]

Thank you that was really helpful!!!!!

[@markhajdari8591]

i have a question where talking on a an really small scale but why he dos not tell use on a food scale larger point of view like if i take supplements in height dose of iron what would happen or what would i need to take to reduce my iron thats what i would like to know what supplement

[@garyhudson3811]

thank you so much doctor, what do you think of Bovine lactoferrin's rule in Iron absorption regarding it's similarity to transferrin ?

[@Legomed]

Hi Gary, the role of bovine lactoferrin in iron absorption remains a bit controversial still, with some studies suggesting that it does enhance absorption, while others do not support this. Further studies are needed. It does seem that lactoferring is an important iron scavenger and has now been found to have many other roles in the immune system, bones, etc. For a nice overview, see the article by Jeremy Brock, titled: Lactoferrin - 50 years on. The reference is: Biochemistry and Cell Biology, 2012, Vol. 90, No. 3 : pp. 245-251. I think you will enjoy it!

[@Neo58964]

What a brilliantly illustrated video.. sir.. continuing on with the question as posted on lactoferrin, recent studies suggest that lf binds to Ferric ions, inc. Iron absorption and thereby in trials alongside with IV iron have given comparable results.. my only query is.. if lf binds to ferric in the intestine and its actually the ferrous that is being transported inside. How exactly will lactoferrin work..

[@hithere-zq4ob]

this is awesome.thanks a million

[@theamaureen6491]

Thank you!!!

[@Legomed]

Only a pleasure!

[@Hiisen]

thanks so much

[@mohitdoshi6662]

If Fe+3 is converted to Fe+2 why is it not called oxidation? Why is the enzyme called ferric 'reductase' While it is oxidation reaction?

[@Legomed]

Oxidation is loss of an electron, in other words, losing a negatively charged electron makes the iron ion more positive. Reduction is gaining an electron and makes it less positive (3+ to 2+). I use OILRIG to remember this: Oxidation Is Loss, Reduction Is Gain. I hope that helps. Kind regards Vernon

[@mohitdoshi6662]

Vernon Louw MedEd thanks man But i was more concerned of the why name of enzyme associated is reductase but not oxidase type As we know enyzme name is based on substrate.

[@daimmehmood4079]

amazing thanks a bunch you're awesome

[@lilo4235]

How do say no to blood tests in hospital when one has anemia caused by blood tests taking blood reducing hemoglobin levels

[@Udita_Roy]

Amazing thanks!!

[@TheTalottaMike]

Iremember Ferrous ... "Just the 2 of us"

[@mohitdoshi6662]

Hipcidin if destroys ferroportin once Those Ferroportin are lost forever When in condition of low Fe as a result of low Ferroportin by hipsidine in past Anemia could occur? Are Ferroportin regenerated once lost?

[@izatisenpai1531]

thank youuu =D

[@09mpotato]

I though DMT-1 stood for divalent mineral transporter 1

[@xDomglmao]

No, it's "metal", see en.wikipedia.org/wiki/DMT1.

[@mallikarjunhugar5414]

We annals1::