Ischemia Reperfusion Injury (HD)

A brief discussion on "Ischemia Reperfusion Injury" .
Topics included:
-What is Ischemia ?
-How Ischemia Causes Injury ?
-Role of Electron Transport Chain
-Proton Gradient & F0F1 ATP Synthase
-Outcomes of Ischemia
-Outcomes of Reperfusing An Ischemic Tissue
-Definition of Reperfusion Injury
-How Reperfusion Injury Occurs
-Mechanisms
-Reperfusion Injury by New Damage
-Reperfusion Injury by Mitochondrial Permeability Transition
-Reperfusion Injury during Inflammation
-Reperfusion Injury by complements
-Graft Failure due to Ischemia Reperfusion Injury
If you like this video do comment and let me know ! Hope it is helpful. Take care.
- Dr. Rabiul

[@Guatavos8795]

Thank you sir A humble suggestion: Your face is covering most part of the video.it would be helpful if we can see the board more,it will help us write notes at the same time listening to you.

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@jodiamc6950]

Indeed salute to you bro, u made the pathology easy, i m a student of third year mbbs, i ve just gone once through it, and i got something that what would i say incredible......

[@RabiulHaque]

Thank you for liking my videos. Best wishes from Bangladesh. :)

[@mohamedihsaanhuzain133]

@@RabiulHaque Thanks from Sri Lanka Thank you Akhee

[@macpere7]

Thank you Prof. God bless you and your family

[@danielaalejandraberrioszam7980]

Really helpful, thanks a lot, your explanation was very clear, greetings from Chile

[@yongcho8632]

Very informative lecture! I really enjoyed it. Thank you so much, sir!

[@bodycareforhealth8656]

thank you your version was clear concise and made sense of a great deal of complex information, very grateful for your excellent explanation

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@MEDPRO_DOC]

thank you sir.!! this video was very help full for me.. keep uploading such videos,really you are doing a great job..

[@khuloodalasiri1]

Thank you so much Rabiul for your effort and time in making this video it was really useful for me. Keep doing what u r doing you r helping a lot of people out there in understanding lots of concepts in a simple way

[@RabiulHaque]

Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)

[@kundalapukeni1327]

This was very helpful. Thank you

[@bongiwefaith6316]

thank you for your lecture i was going to write my exam and you helped me so much even my book was looking easier after watching your video,keep it up God bless you by letting our future to be bright and easy

[@RabiulHaque]

Thank you for liking my video. Glad to know it made your books looking easier. I have just uploaded a video on thrombosis. You can check it out too ! Here is it's link : Thrombosis : Definition, Pathogenesis, Morphology & Fate Best wishes from Bangladesh.

[@Fatma-kl9lp]

Thank you for your perfect and simple explanation

[@RabiulHaque]

Thank you for your feedback. Take care and best wishes.

[@irena3407]

thank god you brought the teddy, i was going to run away hahaha

[@RabiulHaque]

Ha ha ha. The "Teddy Thing" that I sometimes do was actually meant for my students. ( They get scared of Pathology Definitions but they can't pass written exam without writing proper definitions besides other things. So I show teddy to keep them calm and focus so that it doesn't seem too difficult for them) Glad it worked on you too ! Best wishes from Bangladesh. New video coming in 2 days from now.

[@ridhazainab3225]

Commendable Sir...I Respect u sir for ur outstanding hardwork to deliver such great lecture... U cleared the concepts from Roots... Lots of respect from Pakistan🇵🇰

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed.

[@GirlyGirl8D]

19:48 AWWWWWWWWWWWWWWWWWWWWWWWW OMG SO SWEET. Like wow!! You are a outstanding professor, thank you for sharing your knowledge in such a clear, simple, step by step way!!! Thank you so so much!!!!!!!

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@GirlyGirl8D]

@@RabiulHaque Amen God bless you

[@edanur1193]

thanks a lot for this helpful video and i actually like the fact that you are close to the camera sir, because that way i feel like we are talking face to face so my all attention is for what you say, which helps me a lot because i have ADHD. I find it very helpful , thanks a lot for lecture.

[@RabiulHaque]

Thank you for your feedback. Take care and stay safe.

[@sarahha.4267]

thumbs up for you and this teddy bear

[@punamgurung1426]

your lecture is very very easy to understand and very fruitful. Thankyou for your effort.please keep on making such tutorials. Thankyou very much

[@RabiulHaque]

Thank you for your feedback. Take care and stay safe.

[@nabilanuzhat1331]

your videos are really really help full....pls keep up the good work....may ALLAH bless you..

[@RabiulHaque]

Nabila Nuzhat Thank you for liking my videos. Glad to know they were helpful. Best wishes from Bangladesh. :)

[@vrepel1212]

Amazing! Thank you very much!

[@RabiulHaque]

Thank you for your feedback. Take care and stay safe. :)

[@sethinet3651]

Excellent presentation..You are helping me. Thankssssss

[@RabiulHaque]

Seyo bala Thank you for liking my videos. Very happy to know they are helpful. As always, best wishes from Bangladesh.

[@johntindell9591]

Thank you 👍🏻

[@Dr.Bedradi]

You saved me!

[@rehammj5935]

You help me a lot ☺️..thanx from Iraq

[@RabiulHaque]

reham mj Thank you for liking my videos. Best wishes from Bangladesh.

[@athulapadmasiri4616]

Thanks for ur vedio.it's very helpful .if u can update other system also

[@isabellaalexandra8689]

Very helpful. Thank you so much

[@RabiulHaque]

Thank you for your feedback, take care and stay blessed.

[@kodapaswathi5281]

Thankyou so much sir.... your lectures are really very useful to me for learning pathology by Ur vedio it is very easy to learn...

[@RabiulHaque]

Thank you for your feedback. New lecture on chronic lymphocytic leukaemia is now available in the channel. Link: kzbin.info/www/bejne/iarTpaWlra-Uic0 Take care and stay blessed.

[@zhouduck]

Hi, thanks for the video. could you please explain how ischemia diminishes anti oxidant agent inside the cells

[@drusilla9296]

Thanks alot professor..pharmacology videos will be helpful too....🤗🤗🤗

[@davidbrennan8916]

Great video, thank you very much

[@RabiulHaque]

Thank you for your feedback. New lecture on chronic lymphocytic leukaemia is now available in the channel. Link: kzbin.info/www/bejne/iarTpaWlra-Uic0 Take care and stay blessed.

[@med4kmd]

Doctor - Very helpful video. Can you please comment on long term effects of reperfusion injury? Are there different grades of it, i.e. mild/moderate/severe? Is IR injury somehow different depending on the type of tissue - i.e. skeletal muscle vs cardiac or even nerve tissue vs vascular - such as in severe, prolonged compression or compartment syndromes? Any new ideas about treatment? Thanks. BTW: loved the teddy!

[@walidx9874]

Sir You nailed it !

[@RabiulHaque]

Thank you for your feedback. Take care and stay safe. :)

[@muhammadishaq-wx9xh]

From 20 of this months i m a student of mbbs 4th year so respected sir i need special patho videos per chapter (full chapter)

[@lesliecasachahua14]

Really helpful, thanks a lot !!!!

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@Cute_moon244]

Hi there, can u please make a brief video about the impaired tissue perfusion related to the haematoma? thanks for the great jobs.

[@DrMasfiqueAhmedBhuiyan]

excellent effort..

[@RabiulHaque]

Dr.Masfique Ahmed Bhuiyan Thank you for liking my videos. Best wishes from Bangladesh.

[@sherawatmeenakshi6139]

Sir u always mention I hope my video will help some but truly saying this will help everyone U really doing a selfless and devoting work by Giving education for free I must say People from Bangladesh u r lucky Otherwise studying pathology in Aussie slang is already out of mind Anyways lot of thanks

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@PrabhatKumar-mu1nr]

Thank You Sir.!

[@RabiulHaque]

Thank you for watching my videos and for your feedback. Take care & stay blessed. :)

[@muhammadfahimkhan2223]

very easy to understand sir ..keep it up....i m an India student currently studying in kyamc , sirajgonj ...subscribed and liked. 👍🏻

[@RabiulHaque]

Thank you for your feedback, take care and stay blessed.

[@dalia97668]

Thank you so much ❤❤

[@RabiulHaque]

Thank you for your feedback, take care and stay blessed.

[@yuvashreer8453]

Super sir..

[@fazaljameer4010]

Very effective. Thank you. Are there any techniques that are used to help reduce the effects- say for example during transplants or attempts to restore blood flow?

[@priscillamakasa5693]

This was very helpful👏🏾👏🏾👏🏾👏🏾Thanks

[@elbrusfehruzlu6292]

Thanks you ))

[@chauhangameclub1644]

thanks

[@salahahmed2848]

Thanx faithfully

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@drharshchamoli]

thx sir great videos. sir these lecture are based on robbins pathology? veery very thanks.

[@ranbirchawla1909]

nice work.....thxs

[@RabiulHaque]

ranbir chawla Thank you for liking my video. Glad to know it was helpful. Best wishes from Bangladesh. :)

[@kanantony4423]

Are you following the Dipeptidase-1 lsalt peptide trial to prevent IRI in Cardiac Surgery patients?

[@drbaasharatsiddiqui5594]

Thx sir

[@mohammedrafi4106]

sir like your videos. please tell how cytokines cause injury to cell?

[@akshaydeshmukh7029]

amazing work sir...may lord Krishna shower his choicest blessings on u..

[@RabiulHaque]

Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)

[@sxmmii_gxchaa774]

Thank you

[@RabiulHaque]

Thank you for your feedback, take care and stay blessed.

[@pooja6520]

Thanks a lot

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@srirambhardwaj2343]

Very.informative.video.thank.you.so.much.sir.

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@user-jz2nx6xt3t]

17:06 outcome of reprefusing an ischemic tissue 19:30 definition of reperfusion injury 21:24 mechanisms

[@RabiulHaque]

Thank you for your feed back and indexing. Take care and stay safe. :)

[@_c_ovid1962]

Thnk u.. otherwise I expired waiting for ischemic reperfusion injury

[@user-jz2nx6xt3t]

@@RabiulHaque ur welcome ♥️ Thanks to you for the informative video

[@user-jz2nx6xt3t]

@@_c_ovid1962 ur welcome ♥️

[@muhammadishaq-wx9xh]

sir i learnt many things from u. so keep going and upload short videos on MBBS level......

[@RabiulHaque]

Thank you for liking my videos and for your feedback. Best wishes from Bangladesh. :)

[@hardikbhandari5765]

Sir, in which case hypoxia causes necrosis and apoptosis? Since hypoxia can cause damage to both lysosomal membrane and mitochondrial membrane. So hypoxia induces damage of which membrane first?

[@aplifestyle7778]

Very helpful

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)

[@arjunbarman9102]

thanks sir,

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed.

[@ezaz42090]

vaiya its really a good job....thanks a lot

[@RabiulHaque]

Glad to know you liked it ! I will try to upload a new video on Aplastic Anaemia hopefully with in a week. Take care & stay blessed ! :)

[@ezaz42090]

thakns vaiya...i wish we will get total physiology lecture .... best of luck &take care :)

[@rahulmandole]

Hello Doctor thanks for informative video I didn't understood a relation between restoration of blood leads to inflammation ?

[@med4kmd]

Someone correct me if I am wrong - but I believe it has to do with damaged tissue producing ICAM (intercellular adhesion molecules) on their surfaces, kind of acting as a smoke signal for other particles to come help in repair. These other particles are things such as leukocytes who then with ICAM's help, are able to bind to the vascular endothelium to aid in repair. However, it tends to be more complicated because there are many signals communicating with each other, i.e. cytokines (like IL1, IL-6, IL 10, etc) and complement factors (TNF-a) that also try to aid in repair. This repair mechanism, is actually the inflammation we talk about. Inflammation is helpful in the short term, but when it becomes chronic, it causes more problems/damage than it solves. Also, inflammation can be just local, but it can also be systemic.

[@sumedhas5230]

Sir can u pls upload a video for last minute revision...like 10-15mins video???

[@hdnagarnagar8065]

Dear doc Please make good vedio . Hire them .pay them . Thak make good audio book of histo patho for all . I enjoy inspite being gynec. Say proudly now that I Am from dhaka

[@vickyjohn4489]

ty sir

[@RabiulHaque]

Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)

[@m.pharmawala5514]

sir when myocardial ischemia occur their occur calcium overload

[@sanjaymeena1014]

nice video

[@RabiulHaque]

Thank you for liking this video. More videos coming soon ! Take care & stay blessed. - Dr. Rabiul

[@zainababdulkareem7746]

Thanks

[@RabiulHaque]

+Zainab Abdulkareem Thank you for liking my video. Take care and stay blessed. Best wishes from Bangladesh. :)

[@fangirl1223]

I want this guy and his Teddy bear to be my pathophysiology prof!

[@RabiulHaque]

Thank you for your feedback. Take care and stay safe. :)

[@hamedhosseini4938]

HAHAHA Teddy part lol!! thanks sir

[@RabiulHaque]

Ha Ha Ha. Thank you for liking my videos and for your feedback. Best wishes from Bangladesh. :)

[@hamedhosseini4938]

Thank you sir, some of my close friends are from Bangladesh! best wishes to you to!

[@muhammadishaq-wx9xh]

Sir g upload special patho videos per chapter. nad full chapters

[@ishraqshafeeq2259]

Osmosis is not from a low to high concentration, its the opposite. Your videos are very helpful btw :)))

[@ranbirchawla1909]

just tell me how do you memorize such long definations

[@RabiulHaque]

ranbir chawla Hello, thank you for your question. I try to remember the key words of the definition first. To be honest : I didn't like memorizing definitions when I was a student too but it is necessary for written exams. Also the examiners get a wrong impression here during oral exams if students fail to define according to text book. So my advice would be : try to understand the definition first. You will be amazed to know that each text book definition were written and rewritten on basis of vast numbers of discoveries spanning many years. Try to understand the theme of the topic first. Then look for key words in the definition. Once you have understood the topic and remembered the key words : you will find it easier to remember. It will still take repeated revisions. So make a schedule for revising too ! Hope it is helpful. Best wishes from Bangladesh. :)

[@HamCubes]

It is an immense help to simply memorize the Greek prefixes, suffixes and roots. Then every term is self-explanatory.

[@ranbirchawla1909]

***** thankyou for your advice sir...with gods blessing i passed my MD pathology this year in may...got a lot of help from your lectures...thank you

[@walidluqman8740]

17:00 ischemia reperfusion injury

[@jakegraham1]

If you know the basic concepts then the video starts from 17:20

[@andreasbintorodewanto4070]

💦 👍

[@RabiulHaque]

Thank you for your feedback, take care and stay blessed.

[@ahmadmusawer9392]

Ischemia! Sounds like you're German

[@garaadsan.6191]

please move your face a little bit away.....cuz we want to see the white board well.....and you are too slow.....sorry but it's an advice😊

[@sohelsaheen]

This video is more interesting for those whose mother tongue is NOT English. I guess this is the reason Dr. Rabiul Haque is slow.Surely it is helping those.

[@Richqueenmary]

really helpful thank you so much

[@RabiulHaque]

Thank you for your feedback. Take care and stay blessed. :)