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Survival analysis
Time-to-event analysis
Duration analysis
Analyse the duration of time until event occurs
called
Survival times
Duration times.
Events:
Death
Cured from disease
Finding job
Bankrupt
Getting disease
Censoring
Incomplete
Study follow-up ends
Drop out of study
Emigration
Survival data
Two variable
Time variable
From beginning of study to death or end of study
Event variable
1=failed/event
0=censored
Survival analysis variables
Follow up time
Years
Months
Weeks/days
Outcome
Death
Independent variables
Age
Sex
Drug
Kaplan-Meier survival curve
Non-parametric method
Kaplan Meier method estimates cumulative probability (%) for event at time point
Survival probability as a function of time.
Estimates are presented by constructing a Kaplan Meier plot
X-axis the time
Y-axis probability
Determine median
Log rank test
Compare survival curves
Non-parametric test
H0: Survival time between two groups are similar
HA: Survival time between two groups are different