Beautiful. Understanding this small amount of extra detail makes 'preload' that much more comprehensible to me. KZbin and Khan are resources par excellence.
@ldyprinz10 жыл бұрын
I have been a nurse for a long time and this was one of the best explanations I have ever seen.. Thank you
@chc8929 жыл бұрын
PRELOAD = "WALL STRESS" (units = kg/m*s2) i.e. the same units as Pressure Original Laplace's Law: "Wall Stress" = (P * r)/2*h *So if you multiply and divide Pressure by the same units (meters) you just get Pressure units back!! Tension units = (kg/s2) *Thus Wall Stress = Wall Tension/Wall Thickness *These units are also used by the spring constant k in Hooke's Law Finally Laplace's Law can be used within the ventricle to calculate Preload: Preload =(left ventricular end diastolic PRESSURE * left ventricular end diastolic RADIUS)/ 2* left ventricular wall THICKNESS *Therefore, Preload is a NEW pressure in the left ventricle that wall thickness and inner radius have changed
@Poonamgupta-wn6ni4 жыл бұрын
Khan academy is undoubtedly the one proving every brick (basics)is important if the wall (concept) has to be stable(clear)!I hope one day I will be a part of it☺
@palaknehra Жыл бұрын
Man….this channel is the best thing that’s happened to me ❤
@lizakerr632311 жыл бұрын
You are incredible breaking down difficult pathophys concepts! Thank you very much for helping me understand better. I am currently in nurse practitioner school and highly recommend Khan Academy!
@sophiekreynolds111 жыл бұрын
"another term that people use all the time all the time is... PRELOAD... preload i think it's really important to define....preload is NEITHER pressure nor volume... it is equal to the WALL STRESS... Left ventricular wall stress, at END DIASTOLE." perfect
@haitianhottie10110 жыл бұрын
I understand that preload deals with Laplace's law but you spent more time on that that the actual concept of preload in itself.. still an alright video though just would've preferred further explanation
@ramzeschavez10 жыл бұрын
Preload = Frank- Starling
@VickiBee10 жыл бұрын
This stuff makes me grateful for Omnimedic, the thing they created to do the calculations FOR us; because in an emergency, every second counts. I can't do these calculations in my head like the doctors actually HAVE done. If I could, I probably would have made it into PreMed school instead of just being a paramedic. If I hadn't actually been living with a doctor when I became a paramedic, I never would have made it through capnography.
@kalldesk12311 жыл бұрын
wow...Thank you Sir! you are Awesome
@mariabelinska27978 жыл бұрын
Thank you very much this is really impossible question at my faculty.
@wiamalbouzidi83624 жыл бұрын
thank you so much ! helping us in corona time
@hvn819 жыл бұрын
Fot the very first time somebody knows what preload is!! LOL. Thank you
@mishganfatima29304 жыл бұрын
😂😂
@moragwa11 жыл бұрын
wow definately my new favorite teach SUBSCRIBED!!!
@oscarquiroz33248 жыл бұрын
EXCELLENT! Thank you for a very clear description of a very fuzzy subject I have been able to find. You are an outstanding instructor.
@TheBetadecay11 жыл бұрын
what do you think he was trying to teach? The title is "What is preload". I think knowing how to calculate Preload is essential. People from different disciplines, including engineering and physics, will be looking at PV loops and dealing with preload. I think the math is very appropriate.
@fastbreather11 жыл бұрын
Isn't compliance change in volume/ change in pressure? Please enlighten me on this.
@andreal94587 жыл бұрын
Isn't Compliance change in volume/ over change in pressure? (V/P), not P/V, as the video has indicated?
@local5ab11 жыл бұрын
thanx dr rishi.
@ezzo91111 жыл бұрын
thanks alot
@JR-ou2el11 жыл бұрын
Pressure and volume are inversely related. Yet, the graph shows a direct or positive correlation between the two. How can that be right?
@pangeyi10 жыл бұрын
Good job on explain preload.
@lbryanmillanl11 жыл бұрын
Because it´s about the volume of the content, not the container
@jeffreagan200111 жыл бұрын
You describe elastance as the slope of the EDPVR. So shouldn't you describe it as the change in pressure/change in volume rather than P/V or in calculus terms the derivative of the EDPVR?
@nazmulurrahmannazmul26819 жыл бұрын
thank you sir for it was an excellent lesson and it helped me a lot.
@tigerswallowtail601211 жыл бұрын
Love these vids
@riteshchaurasia80164 жыл бұрын
How does end diastolic volume ant point A increases to 125 to 150ml to point B ..plz explain..!?
@PG035510 жыл бұрын
Excellent lesson
@LubaNikit9 жыл бұрын
r is R_{IN}, not R_{TOT}
@Tomevone11 жыл бұрын
how can u assume the left ventricle to be spherical. since u applied "4/3 π r3"???
@heartshunter8 жыл бұрын
You have to change the video title to Cardiac Preload.
@myh4you8 жыл бұрын
Uhm,preload is not wall stress,that's afterload..or at least that's what my cardiology book says..if Preload is wall stress then what is afterload all about ? Laplace has nothing to do with preload.
@brandonderuiter91578 жыл бұрын
+Mihaela Țolea Maybe pre-load and afterload are wall stress during different parts of the cardiac cycle
@GoToHellHermen7 жыл бұрын
Afterload is the load against which the cardiac muscle exerts its contractile force. (i.e. the pressure in the arteries)
@YanSimonMusic8 жыл бұрын
I'm pretty sure wherever you said "Elastance" you actually meant "Compliance".
@YanSimonMusic8 жыл бұрын
Just finished a physiology course in uni, we used compliance when talking about the CVS, never elastance.
@ghazwanalwan43037 жыл бұрын
Compliance is different from elastance.
@dramaaddict20117 жыл бұрын
no. compliance is V/P
@drownedingames4886 жыл бұрын
Elasticity is the inverse of compliance. A vessel that has high elasticity (a large tendency to rebound from a stretch) has low compliance.
@mariaskf110 жыл бұрын
To the best of my knowledge this is afterload and not preload...
@bentduck10 жыл бұрын
no, Maria, Khan is correct.
@manel74807 жыл бұрын
Afterload is the pressure the LV has to face when contracting an ejecting blood, not before that...
@GoToHellHermen7 жыл бұрын
Afterload is the load against which the cardiac muscle exerts its contractile force. (i.e. the pressure in the arteries)
@ericerickson48765 жыл бұрын
This explanation was so over talked with unnecessary information that I would give it 4 thumbs down.