G Protein Coupled Receptors | Nervous system physiology | NCLEX-RN | Khan Academy

[@msauthor4989]

This guy taught me better in 12 minutes than my professor did in a 45 min class. Kudos dude.

[@naveedkhankakar144]

and my one took more than an hour.

[@sadah22]

@@naveedkhankakar144 and mine took more than five hours 😫.

[@fizazainab1526]

Hahahhaha we are in same category

[@naveedkhankakar144]

@@fizazainab1526 hahahaha yup we are.

[@fizazainab1526]

@@naveedkhankakar144 good luck for your future

[@Mrjmaxted0291]

Besides the VERY MINOR flaw in remaining zoomed in during a certain segment this was a very succinct and well presented lesson on GPCRs. Thanks for posting it up, it's been a great overview to revising the key concepts.

[@asmahaque8558]

I HAVE SPENT 2 YEARS IN MED SCHOOL MANEUVERING MY WAY THROUGH COUJTLESS EXAMS AND VIVAS WITHOUT EVER REALLY UNDERSTANDING THIS! UNTIL TODAY! THANK YOU

[@ozymandias5449]

this is me right now haha

[@Urtoomuchjosh]

thats kinda sad

[@chenchoon8751]

Did you graduate yet? If so, congratz!

[@godferymbadiwe4754]

How far I need a mentor. I just got into my first year of medical school

[@DollyDomDom]

This was perfect! The only thing this video missed was that after ATP is converted to CAMP, CAMP then goes on to activate Protein Kinase A to THEN produce the physiological effects.

[@gmmg834]

Thank you for your contribution

[@juliana-qf]

to talk about this would be a specific video about the second messengers

[@dexkani9993]

Bruh, it's been 9 years, this video needs a re-edit for those precious minutes gone while it was zoomed in

[@ttaylorfaithh]

why did the video zoom in so much i can't see~~!!

[@danjbundrick]

Except for the zooming error, this video was a spot on. Thank you. I heard that it was called "adenylyl cyclase" though.

[@danjbundrick]

+Jai A Meyrick Thanks. I'll have to remember that.

[@danielortega494]

Daniel Bundrick g

[@Vikramt08]

Adenylate cyclase

[@jayrabah8064]

It does the same thing ,but it’s an amplifier enzyme so I think there must be a difference

[@hobobazaar8196]

Adenylate cyclase, adenyl cyclase, & adenylyl cyclase are all the same enzyme. Confusing redundant names, that's science.

[@nonewthing2883]

This guy taught me better in 12 minutes than my lecturer did in a 2 hour class. Levels, thanks dude.

[@gearbanginentertainment7476]

Or maybe you don’t pay attention😊

[@jjocelynjustice]

This video helped the concept of G proteins finally click in my brain. Thank you!

[@santheeshsantheesh5746]

Jocelyn Justice go for The Great Dr.Najeeb if you really want to build your concept

[@nels6991]

Great video! FYI the zoom only lasts for like 30 seconds yall ;)

[@a.stuckmann431]

more like 1 -minute......

[@jonahansen]

It goes from 4:03 to 5:23 for a total of 1:20 or 1 minute and 20 seconds, plus or minus a few seconds.

[@materialgowrl1553]

well with subject like this, every second is crucial, the dude fucked me up

[@hudhaifaahmed5738]

This is the best video explaining GPCRs out there. Tysm

[@joeanderson7841]

Thank you sir, it helps me a lot for my final exam

[@cmgkk]

Great clear explanation. I studied this back in undergrad and want to carry out an experiment now in my PhD where I inhibit G-alphaS and see downstream function. I need a quick re-fresher and this hit the spot! Thanks!

[@roselynyeboah5974]

I tell you am wid u on this one same here am good to go now😅

[@nampotiwong9863]

This video saves my 1st year as a medical student!!!!! Thank you so much!!!!!

[@DuyNguyen-qv3pi]

Thank you so much. I went through my lecture slides, recording but still not understanding a piece of information like you did in 12 minutes. I am so grateful to be here with other students.

[@exemplarypersonality6562]

Same here, the lecture and audio from my boring lecturer was always inducing sleep

[@tiruvgiri1519]

How hours of boring lectures are made into a 12 min riveting knowledge is always going to be a mystery to me #Khanacademy. Thank You for saving my life btw

[@stephyunion]

I like the way you explain this 5-full-pages theory in a simple way. Thank you! This helps me for my tomorrow exam ehehehe

[@Hamzahaisha-fu7mf]

I can't unlearn this ,you deserve a huge hug for this❤❤

[@thanatosiax]

MY PROFESSORS COULD NEVERRR. THANK YOUU 🥹🫶🏼

[@FarheenFathima397]

Greatest video ever. loved it. Thank you for being alive.

[@jess100ize]

What would I do without Khanacademy?? Great explanation, as always😁👌🏼

[@alisthompson]

Please fix the zooming issue!

[@oxysmoxy1977]

You have to change it to full screen, it worked for me :)

[@sherhorse]

@@oxysmoxy1977 doesn't work

[@mennatallahmaher5967]

Amazing I love it ❤❤❤

[@rubyyxlc3936]

5:23 continued from zoom out

[@dilaozut]

Your speech was so clean that despite my poor english i could have understood you well. thank you :)

[@eliawilckriph1269]

for the first time iunderstand the concept of GPCRs. Thank you

[@humzaalam4823]

This helps us so much even if it was made 8 yrs ago

[@soumyanag2328]

You have just activated my G-Protein awsm Khan Academy Simple Smart and Conceptual what else do we need

[@leerunkang8237]

Thank you for the simplest , you explain better than my professors at the collage and for free

[@jadattia6723]

great job . thanks from Syria

[@anilocm5457]

This is a savior 👏

[@Lana-wu2po]

So good. Worth my time

[@喬F]

Brilliant. Really helpful.! Thanks a lot

[@HashemSmashem]

Lol did a cat jump on your notes @7:45? 😂 Awesome, clear, accurate, and well explained video btw. The zooming-in issue wasn't very hindering in terms of understanding the concept, but it would be that much better if it was fixed. 9/10

[@xrelaxbear]

thank you so much, i learned more from this video than i did in a 2 hour college lecture..

[@bwiremartin805]

please help me with the kind of textbook that you guys use its really very well understood

[@atulprasadarya8873]

Way of teaching adorable...

[@gaiaromualdi]

Thank you😭😭😭

[@loserlover6668]

Omg! I love this channel

[@mahmoudahmed3468]

This kind of videos doesn't even deserve 1 dislike ❤️❤️

[@yashadhikar]

Helped me through my exams!! Thanks!!

[@chenlynn951]

WONDERFUL!!! I learned more from this video than my 3-hour-long graduate class!!! THANK YOU VERY MUCH!!!

[@kinkinib]

Thank god for Khan Academy

[@user-yy5qi9fi7b]

Any thoughts on fixing this video? It is a wonderful explanation worthy of an unspoiled presentation in true KA style.

[@markgamble7699]

Great video ... Alpha-Omega

[@lizj8921]

Made this sooo much easier to understand!

[@hinashaukat246]

Finally got the concept of g protein ,thanku for this work 👍

[@anaherrera4805]

Excellent explanation!! Thank you

[@andreeadavidean2787]

Thank you, i finally understood this!

[@hamenyimanarogers8664]

wow. so nice. however i haven't understood the connection between the heterotrimeric complexes and the GPCR. Would you explain please? thank you

[@learnteach2learn729]

tHIS MAKES SO MUCH SENSE

[@katefuglestad5894]

Very helpful! Thank you. The visual really helped.

[@johnmulemwa6609]

Wish harper's was easily understood as this........

[@khamikos1]

excellent presentation. perfect. thanks from Greec

[@maryamsed6023]

Woow thank u so much, u explained such a hard tissue sooo easily and clearrrr, ur greattt

[@ruksanakhan4989]

Informative video... thnx a lot

[@zainebmazin6274]

I’m so thankful ❤️❤️❤️❤️❤️ for this video

[@memuethel4910]

I'm overwhelmed with joy, I finally passed my NCLEX RN after three trials and I almost gave up until I met this God sent. Please join me celebrate my helper Dr Brooks for his consistent assistance showed to me during my preparations for this exam. If you want nclex to be history to you, contact Dr Brooks via text or whatsapp on [phone].

[@imani6547]

Thank God for you

[@juandiegodistefano335]

This video was amazing.

[@colindaines3552]

Super helpful video!

[@poojachaudhari1331]

What an excellent explanation

[@AJ-rd6ez]

Wow this is SO helpful!!!!! Thank you

[@aleenasajan936]

Thank you sir 😇🙏🏻

[@sarabe2930]

i couldnt get the topic on my lecture but now it is all clear! thanks a lot! Thumbs up :)

[@HoosierHmstrdr94]

The zoom problem doesn't last long and you can see what happened shortly after it is corrected. Be patient. You'll get it!

[@adenmadi]

Thnx for the explaination 👍

[@jonxthxn1]

Thank you so much for this!

[@N98-l4n]

EXACTLY what i was looking for!! thank you!!

[@الثبات-ل2ط]

Thank you! Good video

[@anwaralshafy4472]

Amazing video ❤

[@friendspark587]

Thank you so much for this. Really clear and helpful. God bless you❤❤❤❤❤❤❤

[@dr.zaina.0]

Thank you very much that’s help me more 🙌❤

[@SiberianHuskyF1]

Thank you :) You've made final year physiology a little easier.

[@AlanRasoulMentor]

what! you were whatching this on your final year?

[@drnykterstein_]

we read this on first year

[@kobingsubu]

Wow , very well explained 👏👏 i always get scared when i hear g protein coupled receptors (sounds scary right) but now that ive tried to understand its so simple thanks khan academy

[@96cabero]

wtf man

[@azeylacalaty3182]

Cabero lol whatcha sayin‘

[@rchen6929]

You saved my life

[@evaafif7239]

Really helpful 💕

[@Godstead]

Want to like this video 10 million times

[@jarromflightfeather]

Does the GTP replace the GDP? Or does a phosphate bind to the already-bound GDP creating GTP on the alpha subunit?

[@farhadforoutan1784]

Thanks. I like your hand writing

[@racheldenapoli2278]

Thank you so much I am forever grateful.

[@shankaraiahgoudmamidi4601]

That was a very useful and helpful video

[@aches6652]

really helpful ..

[@EvilMia1]

Greetings from Sweden! Thanks for a great video! Dont know if it really matters, but it's an adenylyl cyclase (not adenylate) according to my biochemistry book.

[@hjorthan]

Both terms are used. I just checked two of my danish textbooks. Biochem-book says 'adenylate' and Pharma-book says 'adenylyl'. But I also seem to recall that previous english textbooks I've read uses 'adenylate'. I guess it's just a 'cultural' thing, regarding what system you use to name the functional groups.

[@passcomcompass2623]

Both terms are used, adenylyl is kind of an old fashioned name, some of the pictures of researches my lecturer shown us use adenylyl, but adenylate is used in most universities in London as as far as I know.

[@mermaidtale1]

they use both here at the University of Otago :)

[@shadychapook3944]

Thank u so much it was soooooo useful ♥️

[@SuperAlbalawi]

I really thank you sir for this great video, tomorrow I’m taking a physiology exam

[@roshanibhavsar1756]

Awesome video sir 😍😍😘😘👌👌👌tx sir🙏🙏

[@hippocampus4910]

Excellent 👏

[@arunabhSiddhartha]

Very well explained!

[@sudhamsuupadhyay7858]

A thank you from NEPAL.

[@joeburreaux7953]

Doesn't cAMP have to activate Protein Kinase A (PKA) first before those physiological responses occur?

[@momikhattak5533]

Nice explanation

[@rocketbabydoll93]

This video is my lifesaver. Thank you so much!

[@dhananjaymangal9910]

very nice presentation...

[@drdivishaverma6242]

too good! 👍🏻

[@stellareyes207]

It is very good explanation.

[@SPX3455]

Do inverse agonists cause the opposite biological cell function to be activated compared to antagonists?

[@BastiPROTON]

5:50 GPCR explanation starts here

[@sindhulatha9376]

thanku for teaching,its awosome....

[@Hiphop101ize]

I get that the alpha subunit of the g protein acts s a regulaator after it's activted. But wht do the bet and gmma subunits do? Is their only functtion to block the alpha subunit from being activated all the time?

[@amreshrandive5371]

Very Helpful explanation. Thank you.