Advanced NMR Applications - Jane Wagstaff

The LMB NMR Facility contributes to projects across the full range of research activities at the LMB and is part of an integrated structural biology approach, bridging the gap between biophysical measurements and structural determination. It is a biology driven facility that makes NMR accessible to the non-specialist user.
Facility staff draw on their diverse scientific experience so that all relevant advanced NMR methods can be implemented and adapted to the specific needs of the LMB scientists.
In this video Jane describes the different types of advanced NMR experiments, the limits of sample size and the ideal sample amount and quality. She discusses how different NMR relaxation properties are related to molecular motion and how they can be used to look at interconversion between states or probe rigidity and unstructured regions in proteins. She uses two projects on ubiquitin and a protein LITAF to illustrate how NMR can be used in to investigate protein structure and dynamics.
The Biophysics Facility is headed by Stefan Freund.
Read more about the facility here: www2.mrc-lmb.c...
You can find more videos from the LMB 2021 Biophysics Techniques Lecture series here:
• Introduction to Biophy...
Other playlists you might be interested in:
Next Generation Biophysics Symposium 2020 - • Next Generation Biophy...
Electron Cryo-Microscopy Course 2017 - • Electron Cryo-microsco...
RNA Seq Course - • RNA-seq Course 2020
LMB Crystallography Course 2013 - • LMB Crystallography Co...
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