Long Covid and Fat Metabolism Mitochondrial Dysfunction: Getting Outside Might Be an Answer

Roger Seheult, MD of MedCram discusses long covid and fat metabolism mitochondrial dysfunction. See all Dr. Seheult's videos at: www.medcram.co...
(This video was recorded on November 2, 2022)
Roger Seheult, MD is the co-founder and lead professor at www.medcram.co...
He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine.
LINKS / REFERENCES:
Sunlight and Protection Against Influenza (Economics & Human Biology) | www.sciencedir...
A geographical approach to the development of hypotheses relating to Covid-19 death rates (Melatonin Research) | www.melatonin-...
Signatures of Mitochondrial Dysfunction and Impaired Fatty Acid Metabolism in Plasma of Patients with Post-Acute Sequelae of COVID-19 (Metabolites) | www.mdpi.com/2...
All coronavirus updates are at MedCram.com (including more discussion on delta variant covid, COVID Delta, COVID children, natural immunity COVID 19, and more).
MedCram Update 46: • Coronavirus Pandemic U...
MedCram Update 47: • Coronavirus Pandemic U...
MedCram Update 132: • Innate Immunity, Inter...
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[@Medcram]

Please go to medcram.com for further videos on medical topics including continuing medical education units for healthcare providers.

[@gabrielj.daveiga2470]

Would autophagy improve mitochondrial dysfunction?

[@keywee849]

"Aiders and abetters of Nuremberg Crimes are equally guilty, and have also been persecuted, convicted and executed." Francis Boyle

[@richardtheriault9121]

@@gabrielj.daveiga2470 Similar thoughts for me. I'd love him to research and report on keto, omad, and intermittent fasting, even of a week or two, as repairs to metabolic issues and mitochondria. Do ketones produced then help or hurt such symptoms and metabolic dysfunction?

[@richardtheriault9121]

I'd love you to research and report on keto, omad(one meal per day), and intermittent fasting, even of a week or two, as repairs to metabolic issues and mitochondria. Do ketones produced then help or hurt such symptoms and metabolic dysfunction? Would an infrared space heater inside be of help indoors in the cold months?

[@djtomleeuwen]

As the days are getting shorter, less sunlight, could over-the-counter Melatonin be beneficial against fatigue from Long-Covid? And if yes, how many mg's?

[@junior10199]

Long COVID, between the fatigue and neuro symptoms, sounds like what I experience with MS and apparently mitochondrial dysfunction is an issue in MS. Over the years I’ve found that exercise and diet make a huge difference acutely. What I eat, supplements and my activity matters and has an acute effect day to day.

[@nellatl]

What pisses me off about this advice is doctors and people don't seem to understand it's a catch 22. Long covid is extreme exhaustion. The remedy is to go outside and get more excercise. BUT, going outside and getting requires energy; which u don't have because of EXTREME EXHAUSTION. It's like telling a person paralyzed in a wheel chair the remedy is to walk it off. Not a practical remedy.

[@pressme71nz]

@@nellatl Perhaps the advice as it is stated is a bit crude, but if you adapt the amount of exercise to your tolerance levels, then it can be beneficial. “Exercising” needs to be understood as a spectrum from barely moving right through to high intensity. Walk 50m if that’s all you can do. But try and do it consistently. If it’s too much and you are worse off the next two days, drop the distance back.

[@aurorasurrealis1032]

@@nellatl Get someone to walk with you outside and just sit on a chair. The sun exposure will be the most important part.

[@CovidConQuitTheCensorship]

It's the jab, wake up

[@junior10199]

@@nellatl I’ve been there. Sleep for a million hours. Feel better for an hour, then exhausted again. Medication changes turned that around. I can work a 12-hour day now. At the time though, I sometimes FORCED myself to exercise. Afterwords, especially the next day, I was always glad I did. Walks helped. Making it a routine was best.

[@alexandrecouture2462]

Very interesting! I have LC for pretty close to 2 years at this point and it gets much better during the summer. This might be the reason. Thank you!

[@drunvert]

Tanning beds

[@alexandrecouture2462]

@@drunvert This is UV light. He is talking about near infrared light.

[@mwngw]

Just the opposite for me. Summer heat puts me down.

[@melodymelomaniac]

I ALWAYS feel better when I spend time in the sun 🌞 It's crazy though that people were suggesting this from day one and not one person from the CDC or government mentioned the importance of that once in the last 2.5 years....

[@stitcheruk1150]

Watch Dr. John Campbell. Vitamin D3 - so necessary.

[@BestCoachOnEarth]

I have long-covid for more than 2 years now and entered summer twice now. Specially the first weeks of nice sunny days are extremely nice and i feel almost normal but this levels off over time. Its like producing melatonin thru sunlight is limited.

[@ericrawson2909]

They told us to stay indoors. Idiots. (Or are they not idiots but evil?)

[@billmitchell1955]

They didn't want any other alternatives to the vaccine.

[@zissler1]

rhymes with weevil.

[@pattyg.4872]

I’ve never had covid but have this issue from 2 pfizer in 01/2021. Have been diagnosed with Long Covid and ME/CFS by my Pulmonologist. Makes sense.

[@cpt_kirkwood]

Same. Injured after second dose of moderna. Everyone I know who has long haul or is vax injured believes it’s spike toxicity. Encountering the spike is bad news. In our case, vax spike did us in. Not sure why we were susceptible while others were not. I have been ill since March 2021. I’d love for medcram to cover this topic but I understand that it’s “politically divisive”. Me? I’ll admit that I just want acknowledgement so I can get my treatments paid under insurance and/or get compensation for all the lost income, debt, and all of the money I had to pull from my retirement to pay for expensive treatments.

[@pattyg.4872]

@@cpt_kirkwood I get ya…. It’s so frustrating to be denied… long covid clinics won’t take me because I’ve never had covid. I see a Functional Med Doc who has helped some, but after almost 2 years I still have a ways to go, constant shortness of breath. I’m sorry you’re dealing with this too! Prayers for us all.

[@debbiel4194]

Stumbled on your comments. My heart goes out to you both. You deserve to be heard. You deserve help and answers. I'll keep you both in my prayers. By the way I'm unvaccinated but care about people who are suffering. God bless you 💝

[@cpt_kirkwood]

@@pattyg.4872 it’s wild how many people in comments are saying they are injured. I wish KZbin channels like this one would respond to and do research on people like us. When I first got sick, I had never heard of anything like it and doctors were very sick to deny vax injury (at first). It was a long and lonely road.

[@mikehodgetts4864]

I love your videos and often recommend them to others. Several week ago my wife who is nearly 80 came down with COVID. She was prescribed Paxlovid and was better after a few days but was very slow getting back to normal. I got her to watch some of your training videos with me and she agreed to using near IR. We got a big old quartz heater out of storage and set it on the floor near the table where she reads her newspaper. Set on low (about quarter scale) you could feel the I.R. on your skin, but it was not too hot to be comfortable. She is now about back to normal. Thank you.

[@simonshakespeare82]

This is really interesting, I put on 30lbs since having covid & it felt like it happened overnight I’ve exercised regularly all my life, I have a home gym now & train regularly never been overweight & if I did ever need to shed a few pounds I could focus & do it no problem The weight went on with no real change in my diet & now whatever I seem to do now the scales just won’t shift

[@joejojo5966]

ask your doctor first but look into intermittent fasting, weight comes off pretty easily. but please check with your doctor.

[@larryc1616]

Average weight gain with long covid or chronic fatigue syndrome is about 30lbs. This is because this disease has disabled you, slows your metabolism and the insomnia/sleep disturbances. The weight can only come off as you get better. Eat as healthy as you can, but don't focus on losing weight, focus on getting better.

[@wzupppp]

Same

[@perlamargarita8040]

I've been overweight all my life, dropped 20 lbs in hospital with COVID then put on 30lbs after. During the summer I'm able to exercise quite a bit-outdoor walking- and finally this year got 20 lbs off, but what a struggle! Sunlight is key!

[@kaycenta884]

I lost 30 and can’t gain it back.

[@Sophal27]

My hypothesis is that insulin resistance impairs beta oxidation. Metabolic syndrome is clearly associated with severe covid and I suspect long covid too.

[@maupinmaupin1472]

Thank you Dr Seheult, Your consistent brilliance sheds light and brings order to a crazy confusing world.

[@tessav4487]

This video helped me understand what was going on and led to me finding a possible FIX! I have started supplementing with L-Carnitine as I think that must be my issue with 4 years of blunted energy and function due to long covid. I am shook that this $13 wallgreens level supplement is totally changing my life. But that fatty acid transfer is SO important!! Might be something for others to look into if they have similar issues.

[@meiyuc22]

i need to listen to this 3 times.

[@Scienceaddict147]

A very interesting video indeed Dr Seheult! As always. How would you propose that people in the far deep of the northern hemisphere access NIR, at this time of year? Will devices that produce this give equally good amounts of NIR?

[@lingzhang2341]

Maybe, replace the light bulb on the ceiling of a bathroom with a 200w infrared one and use it for certain amount of time everyday ? Is there any research on this idea to treat long COVID ?

[@Scienceaddict147]

@@lingzhang2341 That is what i would like to know too. My wife struggles with her long covid, but since we live way north, it is basically no sunlight for the next coming months. And also, what is the recommendation for such a device/bulb. Watts, length of exposure, distance etc. I have seen these infra saunas, but they only emit far infra light.

[@chillpauly]

This all makes me wonder if this kind of research into long Covid may also be applicable or at least tangential to Chronic Fatigue Syndrome. My wife suffers from CFS, and there is so little known about the mechanics of the condition, and therefore treaments/therapies are often extremely general, lacklustre, with little hope in sight for recovery. I wonder if the same kind of tests may be able to be performed, like was shown here, to see if mitochondrial dysfunction may also be playing a significant role in CFS.

[@denisedevoto2834]

I have CFS and am following all this research on Long Covid very carefully.

[@myhealthobs5290]

@@denisedevoto2834 same , 10 years cfs. I've tried all sorts if diets and amino acids, melatonin etc, nothing works. the big clue I think is at griffith University in Australia, they found calcium ion channel dysfunction in both me/cfs and LC.

[@user-ch1bd8hb1l]

Fascinating. Thanks for making this!

[@odeszarules5125]

Myalgic Encephalomyelitis. Same disease. Also affects mitochondria. It’s most likely also associated with the limbic system (fear created by C19 hysteria) and genetic susceptibility

[@Albopepper]

In addition to melatonin, wouldn't other sources of anti-oxidants help? This research might support sleep & sun. But why wouldn't it support a low inflammation, high anti-oxidant diet as well? Plants are loaded with a variety of polyphenols which ought to combat ROS. I think this could make a case for a minimally processed, plant-based diet, full of nuts, seeds, berries, greens, etc. And wouldn't a reduction in fat intake help to reduce the fuel being thrown on the fire? Another reason to minimize consumption of animal products.

[@someoftheyouse]

I have no medical training so forgive my ignorance, but if the spike protein on the virus is an ACE2 trojan horse, and the immune system learns to attack that structure, is it possible the immune system also learns to attack the ACE2 protein leading to the AT-II AT-1,7 problems you described in an autoimmune fashion?

[@dlloydy5356]

Wow fascinating stuff. I’d be interested to know what impact using ACE2 inhibitors/blockers has if any? I remember it being a concern/then potential benefit early in the pandemic. Thank you

[@eugeniebreida1583]

Good question! (for Dr. Schuelte, vid on this idea?)

[@zissler1]

Nicorrette gum is amazing for my lomg haulers.

[@JudithTheROSE]

What about people that take HBP medicine that inhibits ACE ?

[@Psychx_]

The mechanism of antioxidant formation via ACE2 would suggest that lasting symptoms may be caused by aquired autoimmunity.

[@goodlux777]

Great information!

[@hagbard72]

Infrared lights useful? Cloudy in winter months here.

[@Medcram]

Could be. Studies have showed effects.

[@hagbard72]

@@Medcram Thanks.

[@shanearmstrong7197]

As well sun redbinfrared light helps boost mitochondrial biogenesis -not just its health-And nitric oxide level

[@danilonepomuceno5918]

thanks dr seheault for the valuable info.

[@ladonnabellavillalobos9627]

There’s something I really don’t understand, I was in the ICU for two months, then the regular part of the hospital for one month then I had to go to a different place for physical therapy, and speech therapy because my daughter found me on my bedroom floor, and she thought I had passed away, I don’t even remember that I couldn’t remember my address anyway the thing I want to tell you and I haven’t even watched video yet they were giving me insulin shots in my stomach every day I don’t know how many it was terrible and steroids blood thinners and I don’t know what else I felt like a toxic waste dump, I had so many weird dreams, but I ended up like 200 pounds heavier and width and all that time I still got about 30 more pounds to go, when I first went to see my primary care doctor for my check up after I got out of the hospital he Well he did a full blood work up, and my A1c was so high it didn’t even register I think you said the highest was 450 but again it didn’t show up so high, and then the thing they gave me to check my blood sugar For a long time it was an error because it was too high I wanted one of them glucose monitors but they wouldn’t give me one and then my eyesight started getting bad and I had neuropathy in my feet I was very healthy before that happened, but all them toxins they were giving me my body is not even used to taking an aspirin I am used to eating a very clean healthy diet and using functional medicine herbs spices and supplements plant-based supplements not synthetics another thing that showed up I didn’t hardly have any vitamin D3 now I know I had a lot of vitamin D3 before I got that virus and I was taking that K complex the 27 or whatever and extra virgin cod liver oil, I also broke my humerus bone in my right arm and it broke snapped in half they couldn’t do surgery on me because of course I was so sick so they put some kind of cast on my arm to fuse it together I believe I was 64 then, I still have this awful taste in my mouth I can’t see very well and I had 15-15 vision, now I am on oxygen 24 seven I’m losing the weight though I’m glad I knew how to eat healthy and I completely cut out anything with carbs in it nothing tasted right anyway, he subscribe me cholesterol Lori medicine statins to different kind of type two diabetic medicines who is I know as he prescribe me now 18 medication‘s, but I told him the truth it I tried to take the medicine and my body rejected it , I’m happy to report that I figured out what was wrong with my eyesight they probably started with such high blood pressure blood pressure blood sugar, but it’s the lenses and the cones in the back of my eyes because I was stuck in this apartment and I was no longer seeing anything long-distance so I started doing exercise for my eyes and it’s helped a lot but my eyesight still blurry, I know you gotta take your house into your own hands I don’t know how anybody could take that many medication’s to different inhalers that For anxiety I better end it here it might be too long make me so nervous so they gave me alprazolam

[@fionen]

FASTING! It cured long covid for me.

[@markleonard4452]

Is intermittent fasting ok? I fast til lunch each day and it's helping. May be I should fast longer though

[@davidsweeney111]

Why does ROS cause hypoxemia?

[@mavisemberson8737]

I had a gastric fever episode just before Covid 19 was designated the problem in the worldwide epidemic. I have just come to the conclusion that my gastric and other problems which do not get better are somehow connected to Long Covid. NZ Summer now and often warm weather. I go out onto a N facing balcony to get some sun light though when the wind allows.

[@leercoach]

What about Advanced Glycation Endproducts?

[@melissapollime2271]

Here is the weird thing when had long Covid. I was unable to get a sunburn! Could stay in the sun for hours. Also for a few weeks was unable to stand any kind of sunlight at all. 10 minutes of sun overheated me and made me ill. Took Vitamin D every day. This allowed me to finally be able to get out in the sunlight again. Not sure if it was because of the Vitamin D did not burn or effects of Covid. Did enjoy not getting sunburn for a summer.

[@riju1992]

Is long covid due to vagus nerve dysfunction or low energy production by cellular mitochondria.which means VNS-vagus nerve stimulation is the future cure of long covid.then how is BC 007 by Berlin Cures which neutralizes Long covid autoantibodies being pushed for trial?

[@wshyangify]

Would intermittent fasting work if you can't metabolize fat?

[@vrendus522]

Wow' thanks, very good.

[@Intwodeep902]

Can a far infrared sauna help with atp thanks

[@surfreadjumpsleep]

i don't understand. Is this offered as a cure for long covid or is it a prevention of long covid? Can the damage done be restored?

[@christopherellis2663]

Reflected (off of) from. Based (off of) on. " ! "

[@paulocl2]

During covid and long covid I was always trying to stay in ketosis. Do you believe that this may have prolonged my long covid symptoms? I only got rid of exhaustion after taking my first pfizer booster shot, after two shots of Astrazeneca. This happened almost 20 months after I had covid.

[@eugeniebreida1583]

What exactly were you eating?

[@hektor6766]

I'm confident keto minimized my symptoms. Beta-hydroxybutyrate doesn't "burn" the mitochondria with oxidants the way glucose metabolism does.

[@Aa-ji2yf]

What about taking over-the-counter melatonin? Will that boost levels?

[@DApostate]

Does near red light and red light therapy produce melatonin?

[@Rene-uz3eb]

It’s been hypothesized without any direct evidence. My guess would be that since light stimulates serotonin, a smidgen of it makes it into cells where some of it will be converted to melatonin by mitochondria.

[@richardpellis]

How does one test how well our mitochondria is functioning. I don't suffer from long Covid, but I just that my ATP production isn't what it used to be. However, I don't know why or have proof to support my theory.

[@xMo29]

How do we deal with getting sunlight in the winter?

[@Medcram]

It’s harder but still possible.

[@xMo29]

@@Medcram Thickness of clothing goes up, and I doubt perceiving heat will occur. Any thoughts on IR panels in the wavelength range published by Zimmerman et al? Thanks doc!

[@LisaSamaritan]

@MedCram I live in a part of the world, that have short summers and right now have little to no sunlight. Is there any good near infrared lights that you can buy, and use as a compliment? If there is, can you recommend any products/brands? Thanks for all the helpful videos.

[@Medcram]

I’m not aware of any have been tested for this endpoint. But even in the area of the world that you may happen to be in so long as the sun is up you’re going to get near infrared radiation.

[@LisaSamaritan]

@@Medcram Sure, I just want more. I have Multiple Chemical Sensitivity (MCS) and if Martin Pall's theory about the NO/ONOO-cycle (Nitric oxide hypothesis) is correct, then Near infrared might help with that to.

[@javacat]

Or...if a person can't get outside, could they buy a near infrared therapy panel?

[@Medcram]

Yes

[@jjalert]

If the cells are unable to process fatty acids to produce ATP, would it be logical to assume they are utilizing more proteins and sugars? I’ve had issues with hypoglycemia since I had SARS CoV2, with no other health events. It makes me wonder if the glycolysis is somehow in overdrive and burning more glucose.

[@douggrant3431]

I had a pulmonologist testing from my lungs to see how good they were in each time they put me on the machine and I could breathe to do the test they pumped oxygen into me and every time after that my brain fog was gone please explain

[@jackie-k]

The only thing I have going against me is my weight and I am 57 and fairly active, no health problems or medications. I had long Covid that messed with my hot flashes, brain fog and energy. I did a vortex healing! Energy healing and cleansing! We forget the amazing healing abilities of our bodies! It worked amazingly!! Also fasting helps as well!!

[@jayman7101]

What about melatonin supplements? Does that work the same? Also, should we take an antioxidant supplement.

[@benjaminbunny99]

Many people are thinking it’s fatigue when it’s really muscular hypoxia due to endothelial damage.

[@clemensh6214]

Makes sense my VEGF is very high

[@upupina90]

Who says that both aren't linked????

[@concienciayenergia]

Thank you Dr. I was with delta COVID and 3 months in coma in Loma Linda Hospital and after that a lot post COVID issues. Thanks a lot for your research …. You are a light in this times 🥰

[@dianabrown5821]

Does this doctor work at Loma Linda? I live in San Bernardino

[@mintsaturn]

I have been training for 4 years to run half marathon distance. I have never been overweight, and eat very consciously. After having covid-19 in December 2021 and having long covid for more than half of 2022, I am so relieved to watch this. Immediately after being sick I gained 30lbs with no change to diet, lifestyle or exercise level. My energy and performance level tanked to the point where I had to take a break from training. My family and friends would not take me seriously that it was triggered by having covid and I was accused of "not being honest about my carb intake" by my mother. This is so validating because I was staring to believe I was just not in control of my life or that this was the new normal of rounding the bend of 40 years of age.

[@wildhorses6817]

And, please, find some new Friends.

[@bellelacroix5938]

Same. Could have lost a few pounds before covid but definitely was not unhealthy and actually walked every day for about 45 minutes taking hills, to getting covid in February to 20 and have long covid now still. I gained 30 pounds. I couldn't get down to the end of the block for 2 years. Started taking vitamin D felt a bit better. Worked up to walking 2 to 5 miles a day until I figured out I was doing too much because I was starting to feel worse. Backed off to 2 miles a day and cutting out all carbs and mostly eating just one meal a day and I have not, in 7 months, lost 1 oz let alone a pound, and I'm still huffing and puffing walking back home, surprised that it has not become any easier. Sick of it, especially because I have developed an autoimmune allergy condition which at one point was almost life threatening.

[@lingzhang2341]

​@@bellelacroix5938 Thanks for sharing your experience. It's helpful.

[@CourtneySchwartz]

Same.

[@agavictoria]

Yes. So it's a good point. Sometimes obesity is not because of the food intake and lack of exercise. Imagine all those 'fat' people who have to listen all their lives that they are just lazy.

[@monsegeek]

I've watched all your videos in the Light as Medicine series and the amount of evidence supporting sunlight as a valuable resource for illness prevention and even treatment is astonishing. I've been openly encouraging pretty much everyone I know to go outside and get some sunlight ever since. Thank you, Doctor.

[@faikerdogan2802]

Light is not a medicine stop being brain dead. But vitamin D is an essential. Sunlight is one way to get that.

[@monsegeek]

@@faikerdogan2802 Electromagnetic radiation A.K.A "light" (including the many wavelengths your *ignorant* eyes cannot perceive) has all sorts of uses in science and medicine. It certainly is not a drug (if that's what you mean by light not being "a medicine"), but it *is* an important tool for illness prevention and treatment.

[@Blissfulbizz]

I literally was sun bathing every morning till afternoon all summer until I got covid end of July 2022. I worked outside as well. Even when I had covid I laid in the sun because I’m crazy and thought it was healing. But 6 months later I still have long covid and am searching for answers. Light as medicine makes no sense.

[@monsegeek]

@@Blissfulbizz There is no way to know if all that exposure to sunlight had any effect on you. Perhaps it did nothing, or perhaps it prevented you from having an even worse outcome. Whatever the case, I'm sorry you're still battling Long Covid and I wish for you to get better eventually. I will continue to get myself exposed to sunlight and to advice everyone I know to do the same because the science behind seems sound enough to me.

[@marky5493]

@@Blissfulbizz i live in the sun and am an outdoors person, I've had long Covid for 3 years now, if this was true i should have been better a long time ago!!!

[@rlwings]

Yes energy production has been the plight of a lot of Long Covid sufferers... But Covid seems to be a multi-system attacker. Ie, a lot of us have never experienced the fatigue but rather are suffering neurological symptomology throughout the body. Brain fog, anxiety, tingling, numbness, tinnitus, etc... I hope causes and treatments are also discovered for these effects of the disease.

[@karinaemelie1665]

Yes, agree with you, To this day I could feel where the Covid virus wanted to attack, dock and unfortunately intervened to this day. why I fell ill with Covid (nov 2020) (and still have symptoms today), probably due to a stressful situation, a weakened immune system. In addition, I had taken on a holiday replacement (care for the disabled). I work every day on my recovery, more attentive and aware of my body and nutrition, also vitamin D and outdoor activities. ✊✊✊

[@vanesaorozco3524]

I have the same exact symptoms as you.

[@kaytee1617]

Same symptoms as well. I hope for more research for this soon.

[@denicejackson4839]

You might check out Dr. Datis Kharrazian's teaching on brain autoimmunity and inflammation.

[@TSLApilot]

Mitochondrial dysfunction is associated with a variety of diseases, so it is certainly plausible that any or all of the symptoms you described could be triggered by poorly functioning mitochondria. I wonder if any of the many supplements that are touted as benefiting mitochondrial health (or that might improve beta oxidation) could be of benefit in long COVID, given the findings of this research

[@robroysyd]

There is a simple enough randomized sturdy we could do. Take a hospital with two ICU wards and in one only add NIR LEDs into the lighting mix then compare the long term health of the patients from the two wards.

[@karenstauffer1524]

Every time I hear about "long covid", I think about my 12 year battle with longterm Lyme disease. It's a terrible thing to have fatigue, brain fog and cardiac and neurological symptoms that go on and on. Meanwhile, so many doctors (and insurance companies) were telling me it was just "post Lyme syndrome " about which they "could do nothing" and even acted hostile towards me for seeking treatment. Supplements were a big help, as was getting out in nature.

[@paezro]

Sorry you had a 12 year battle, great that you are doing well now. Could you please share which supplements helped you? Thanks and hope you continue feeling good!

[@TBL-AMELIA]

​@@paezro I 2nd this. Would love some help

[@JosDLM]

Please share what supplements you took

[@Fomites]

If it it wasn't just "post Lyme syndrome", what do you think it was? And if it is post-Lyme syndrome, what can anyone do for you? And if your answer is 'nothing yet', what should they tell you?

[@dshepherd107]

@@FomitesPost Lymes syndrome would fall under, post viral syndromes, like long haulers Covid. You may now have a form of secondary dysautonomia. See if if you can find a neurologist that works in this area. If you can’t, try to find a DO familiar with post viral syndrome & ME. myalgic Encephalomyelitis, which has much in common with post viral syndrome

[@allbionics]

Very clear and logical explanation, as usual. I am an engineer and I still got it :). We are machines, from viruses to humans, just terrribly complicated, and even more so once you add interactions and some natural selection sauce.

[@pamelawilson5975]

Please speak on fasting and mitochondrial turnover to rid the body of dysfunctional mitochondria.

[@Medcram]

Yes..I think it’s likely another key to improvement but again we need RCT,

[@kapaul1584]

Been suffering from LC for 27 months. Hopefully a solution can be found.

[@googlesingh9537]

Try intermittent fasting ,and avoid exertion...take a lot and I mean a lot of rest. Take sunlight and calcium..it worked for me..its been 8 months since I got infected

[@briangriffiths114]

These videos are very helpful and I hope that the study's findings are taken up by the UK's NHS which is struggling to deal with long Covid.

[@ashleylala4293]

I’ve had long Covid since July of 2020. I also have thalassemia minor, so I am used to a certain amount of fatigue and muscle weakness. Covid amplified it significantly and added bone pain and Covid type migraines (which involve the sinuses and neck stiffness) to the mix. It’s been incredibly frustrating. Im so tired of nasty comments from healthy people who don’t understand and think I’m just being lazy or exaggerating. I’ve also experienced a lot of muscle and fat wasting. I’m trying so hard to exercise and build muscle but it’s proving to be waaaaaaay more difficult than pre-covid.

[@oscararredondo9672]

Im the same way, did you try any that works?

[@theman-kq2uj]

Did you lose weight from it?

[@theancientsancients1769]

​@@oscararredondo9672How are you feeling now?

[@Eddie07S]

15:52 “... sitting in front of the fire also exposes you to NIR...”. I knew the fireplaces in my house were good for something... And thanks for the great video!

[@RonnieD1970]

Since Updates 61-68 MedCram, OVER 2 years ago, was on this ROS issue with COVID

[@Stan_in_Shelton_WA]

Fall of 2021 I got Covid at age 61. It hit my lungs hard. 10 days in hospital on O2. It took 6 months for me to have a moderate level of energy and 9 before I was almost back to normal. Now I have 50 pounds to lose.

[@jerrywest7068]

Right on target. I've thought mitochondrial dysfunction for almost two years.

[@DaveNagy1]

A couple questions: If this problem occurs during fat metabolism, would reducing dietary fat help the mitochondria "get ahead" of the ROS issue? (This would be a bit tricky, since I assume you would also want to prevent stored body fat from being "burned" as well. A low carb or low calorie diet might be counter-productive if it causes you to start burning more fat stores.) If long wavelength IR is useful for triggering melatonin release (synthesis?), could an artificial source work in a pinch? A heat lamp, basically. I suffer from CFS, which the medical community mostly lost interest in decades ago. I'm really hoping the focus on the new, sexy, and well funded "long covid" will accidentally result in a cure being found for those of that have long-some-*other*-virus.

[@eugeniebreida1583]

All of us with immune dysregulation/autoimmunity etc etc are hanging in there as science funding finally focuses in a much bigger way on 'how to quell or prevent inflammation'. Can Not Wait, I think many are online checking on every long/covid study that rolls off the press. So many angles to inspect.

[@hektor6766]

I was in nutritional ketosis throughout Covid (still am), and caught a variant eventually, but it was like a normal flu, symptoms disappeared after a few days. Academic Medicine will deny keto, but many of the therapies, Remdesivir for example, mimicked it.

[@reannan1462]

Excellent video, and I am super impressed with your foresight regarding the importance of sunlight, and melatonin. Cellular metabolism is at the root of This is all making a lot more sense from a biochemistry perspective. One of my go-to's for taking before having COVID and then after getting COVID was Quercetin, which is an antioxidant. I am now interested in NAC as well. Thanks as always for your excellent information!

[@puppetken]

You should also be taking D3 with A, K2 and Omega 3. And L-Theanine with Magnesium.

[@samuelpilon810]

NADH+ was my game changer after the one you named

[@itsjudystube7439]

Quercetin made me ill

[@madhu_1489]

@@samuelpilon810 nadh is used for what purpose and nad+ also ! For me after heavy calories diet dysfunction my fat metabolism, when I eat it makes me dizzy for hours ? Do you know how work on?

[@samuelpilon810]

@Michael Christopher Nac works for that you take it with your meal

[@nofartcheck3952]

This paper was published a long time ago. At that time, the understanding of long covid was NOT mature, and, more importantly, the world was still obsessed with vaccination. I would read this paper with a grain of salt.

[@toxyl3915]

Thanks a lot, doc! I'm dealing with long covid at the moment and try to be outside as much as possible to get that precious sunlight. Until now I didn't know that this is actually helpful for the recovery :) And it gives me more understanding of what's at the heart of long covid, not having a clue what the cause could be was getting quite tireing.

[@aaronbenesh4722]

What about using Red Light Therapy panels as a treatment for regions without a lot of sunlight or lower temps?

[@leondevries478]

Why not?, but it has to be NIR, near infrared, not those black panels

[@ambroseraftis3183]

Thank you for your scientific analysis of Covid. It helps establish some level of confidence in at least some parts of the medical profession .

[@8Ayelet]

Fabulous MedCram lecture! I am so glad to hear you cover this topic of healing from long Covid! This will help me a lot! 🤗🌅🌿

[@jeffcasey504]

Which wavelengths of NIR are needed most? Finding many narrow band choices. What about old-school incandescent red heat lamp instead of LED? And how long exposure is best? In the PNW, haven't seen or felt the sun in a month+. THANKS DR.

[@pkstiever]

Watch the other videos he mentioned that he made-Light is Medicine and others. They explain in great detail. Morning sun and evening sunset have great properties of healing.

[@jeffcasey504]

@@ssmith2162 Yes, thank you. I live at 45 degrees north latitude and the last day of sun angle above 45 degrees (minimum required to let UVB penetrate atmosphere) was the autumnal equinox. Now we have not even felt NIR heating the skin in weeks, let alone seeing the sun much. Hence my question what LED wavelengths are needed most. Amazon has 600nm and 660nm units, but LEDs only emit at a narrow band of wavelengths, not the broad NIR spectrum shown in Dr. Seheult's previous videos. Thanks

[@eugeniebreida1583]

@@jeffcasey504 I suppose I would google the pricey near IR saunas and begin my research with a good company or two who have done THEIR research, and have the studies for you to peruse. If you find anything please get back here and let me know! (Lat 47)

[@ElizabethMillerTX]

I have POTS, a form of dysautonomia, as is 'long-COVID.' I was bedridden, but have made enormous gains. I keep saying that getting outside/sunshine and getting metabolically well have been key to my healing. I used to dream of you doing the Light As Medicine lecture - then you did it! Then I wished for a mito ep. Christmas came early! Thanks so much for confirming my biases and spreading the gospel. My TLDR Rx: Fatty meat, sunshine/light hygeine and goldilocks prone/recumbant resistance and zone2 training, avoiding insulin hits, seed/veg oils, inactivity, and overreaching.

[@bkingston7207]

Look into thiamine deficiency.

[@johngagliardi8753]

High animal fat diet is key, at least for me. I have never felt better, and have so much energy in all my life.

[@cpt_kirkwood]

What is Goldilocks prone?

[@ElizabethMillerTX]

@@cpt_kirkwood Goldilocks = just the right amount and kind. Prone = not upright.

[@zissler1]

doing 30 to 50k of vit d helped me. took k2 at 450 mg and lots of watee, no problems. also makuna pryon was super helpful as tatking adaptogens at night to sleep, ashwaganda lemon balm, gaba, theanine. definitely avoid seed oils and canola as well as peanuts, and soy. Edit: Also low carbs, grains, and no sugar.

[@lovetolearn881]

My friend had covid so I tested for it way back when it started. I was positive with only some tiredness and after 10 days loss of smell. I am 60. My friends all had symptomatic covid, some worse then others. I started walking outside a decade ago, 10K steps a day which takes about an hour. I'm out in the heat cold rain and snow, year round and I now believe this is why I was n9t phased by covid

[@cjrcapster]

There are full canopy units, that look like tanning beds, that emit 810 and 660 nm light (not for tanning but for mitochondrial repair) . I have one called a Novothor. Look for one in your area and see if it helps.

[@eugeniebreida1583]

May I aak what it cost, and where purchased? Thanks.

[@patrickreilly7256]

Wow... I wish we could discuss ROS w/ ketone metabolism in the same study?

[@bringhomethebasil8729]

I got Covid early on and knew about “Long Covid” before anything was published ! It was going on 4 months after my infection (by that time Long Covid was being considered in the news) and I was desperate to get better.. I came across grounding/earthing after trying many things like changes in my diet .. I went to Home Depot and bought supplies to make my own grounding mat to sleep on and I sweat so bad that night but woke up feeling Amazing ! I had energy again and have been grounding every night since then !

[@theancientsancients1769]

And how do you feel now?

[@LTPottenger]

Fasting will fix it nothing puts you into fat burning faster or has a better effect on the mitochondria!

[@diljitparmar8296]

I was regular joggers about 10 k a day , after getting my first vaccination for Covid I started losing my breath and I didn’t related to vaccination as I got my second shot of vaccination within few days I was losing my breath ,fatigued was not able walk few steps getting disoriented , went doctors they got all the tests and scanning done but nothing wrong I spent almost two months in bed and had about 26 hyperbaric chamber oxygen therapy it took few months and I am still 70% but I used to prior to vaccination it is 15 months. After listing this I conclude that the vaccination caused my mitochondria malfunction

[@daz88888]

Well done for seeing the elephant in the room. Everyone else must be blind! 😎

[@karinaemelie1665]

my great need to lie outside in a quiet, safe place on a deck chair under a sparse tree with a light blanket would probably be just the right thing to regenerate from longcovid. 🙃🌳🙋‍♀️

[@DrGasior]

COVID PASC is also highly correlated with immune dysfunction (change in B and T cell populations, increased auto-antibodies, inflammation, activated macrophages, etc). Could an additional or alternate source of the ROS be from those processes? I bring this up as not sure intracellular melatonin would necessarily address ROS from inflammation.

[@Medcram]

Would love a RCT

[@dwdwone]

Dr. Bruce Patterson and Dr Yo are saying that very same thing. They speculate that a person's unique immune profile determines the kinds of symptoms of long covid that they display.

[@djtomleeuwen]

As the days are getting shorter, less sunlight, would over-the-counter Melatonin be beneficial against fatigue from Long-Covid? And if yes, how many mg's?

[@RainbowCurveCostuming]

If what you say is true does that mean that high latitudes have more long covid cases than southern latitudes (because there being more sun)? Are there any studies that looked at that?

[@eugeniebreida1583]

Which could easily relate simply to Vit D made by the skin, among a whole host of other factors.

[@sapelesteve]

Another terrific explainer video Doc! I am going to send this off to my cousin (M.D.) for viewing as he treats a lot of post COVID cases. Thanks for these important videos and hope that you are doing well!

[@gracemiller3861]

As someone who has LC w/PEM or ME/CFS, which is where we are seeing this mitochondrial damage, I would advise people to be careful about encouraging exercise. If the patient has PEM, then it is important to avoid triggering it and encourage pacing. Exercise is generally a trigger and most cannot safely engage in it. So if exercise is ever encouraged it would be important to add that the patient should not push past what they can do without symptoms.

[@GeorgiGeorgiev-ne9ps]

I am sure there must be life(s) saved from all the knowledge from videos on this channel. I myself took many sunbaths this year and feel better having tan on my skin at the very least. Havent done it in like 3 years

[@sloth6247]

I have long covid and was sweating profusely and it stunk like rust or battery acid and poop smelled like chemicals for a while. I told the doctor and he said it was probably smell dysfunction. 🙄

[@jimmyobvious1651]

Interesting. Also possible you have a very keen sense of smell, like the woman who can smell Parkinsons. Might be interesting to see if you can smell it on other people.

[@sloth6247]

@@jimmyobvious1651 I wish but I don’t think so. I smelled this a year in of being sick. I think I just smelled the oxidation and cell death. I got long covid. It’s a terrifying Illness.

[@jimmyobvious1651]

@@sloth6247 Are you still ill? I'd be interested to see if NAC supplementation helps; it's been talked about on this channel and in articles about long covid.

[@sloth6247]

@@jimmyobvious1651 i didn’t talk NAC but i did take in a lot of foods high in amino acids. I think what’s helped me the most so far is proteolytic enzymes.

[@brianwright9514]

Would love some kind of estimate for exactly how much solar NIR exposure is needed to produce benefit.

[@ChrisKadaver]

I have had ME since 2016 and caught whay I presume was the delta version of covid. And I can tell that long covid and ME is NOT the same thing. Covid can probably trigger ME also, but many of my new symphtoms does not correlate with those I had from ME alone. In my case, I now don't only have POTS I also have (ISK?). I think it's innaproperiate sinus tachykardia. It's triggered by eating usually. I also got a big round spot on the nose with spider veins that pulsates and burns every now and then. I also got pretty severe erectile dysfunction after a presumable cauda equina syndrome that never got properly diagnosed. But I do have polyneoropathy. If it's small fibre or not I don't know. Burning sensation in the "saddle area"? A change in tone of voice and weakend sfinkter. During the worst period I had symptoms that corralates with menieres disease. Severe vertigo for over a month and at one point I lost memory and forgot where I was at the emeregency and also had trouble talking. But I was sent home. They believed I had had a panic/stress response only. Now over two years later most of the symptoms are still there. I have problem with vision and get relapses where I have double vision of light sources and can't use computer screens. A dermathologist suspected (rocasea?) due to the sprider veins on the nose. So maybe my visual disturbances are due to ocular rocasea. Another theory I have is that this triggered ankolysing spondyrlitis sincd I still have both back and hip pain all of the time and I get relapses with worsening symptoms. The worst thing is that nothing have been diagnosed yet except the suspected rocasea. I have spikes in diastolic blood pressure from time to time... I mean periods of weeks. My systolic pressure is most often a tad high but can the later change to super low for some reason. I'm suspecting I've on the verge of developing heart faliure at 38 years of age due to the tachycardia. It took a about 2 years before I eventually got ivabradine for the tachycardia. I didn't tolerate beta blockers and all my symptoms got way worse when I tried them. So much an online neurologist suspected the beta blockers to have unmasked a myastenia gravis I maybe had. I really don't know where to turn. My voice has changed, I have severe erectile dysfunction, It's harder to keep the stool, and my vision is pretty crappy since I see these halos around light sources so much I can't even have a candle on the table in the livingroom in dim lighting. It's too bright and disturbing for me. The worst part is that no one wants to take responsibility to diagnose all these issues just because I never tested positive for covid even though I know they took way too early. I first had a few neurological issues. So they took the test and dissmissed the suspection and then like one week later I first lost the sense of smell and after that everything started smelling like trash for like 2 months.

[@maryburger1232]

So all you people with weird symptoms /long covid/covid are you vaccinated ???

[@RS-rz9xj]

Never had Covid, but wanted to listen to this because mitochondrial dysfunction can affect any of us. I have been taking NAC and Zinc, Quercetin and Glutathione through all of this Co-vid period and possibly even before -- in very modest amounts. I also have exercised all my life and really need the sun. But now being in the northern midwest, I've had to depend on D/K supplements and melatonin in very low doses (I'm an easy sleeper). Just wondering about how to begin to think about all of this beyond covid. Thanks for the talk. It makes me feel that I've been on the right track.

[@kathleenking47]

I've been doing this since covid hit also. The few times I missed, I cought omicron, but had colds worse A difference, was the "fatigue" for 5 days. .along with not tasting anything

[@arevchick]

I just told my doctor last month that covid caused me to gain weight and she said “umm I haven’t heard any of that”

[@Cactusflower2000]

I have had long covid but with a different virus the Epstein-Barr virus for 18 years. Let me tell you chronic fatigue syndrome is a living hell.

[@raymitchell9736]

Dr. Seheult, I've been suffering Long-Covid for months (This BTW is the 2nd time actually I've been through this) ... I am presently going to the docs here in the (SF Bay Area) and they don't know how to treat it, for brain fog they want to CT my brain and talk with a Neurologists, for the breathing thing and the exhaustion with exertion with a mild burning sensation high in the chest. I've taken a lung function test... Ugh! no fun... and need to to schedule a pulmonologist appt. And a crazy battery of blood for A1C, lipid panel, ALT, and so on... plus urine tests looking for ?? ... What they're telling me is that nobody knows what to do, and right now all they can "do" is rule out things. I think these videos are critical, they are HELPING me... I know they've really gotten me further down the road in recovery than subjecting me to what I think might be a battery of unnecessary tests... because they don't know! I would welcome a suggestion if you can offer one. Thank you SO much Dr Seheult... Of course I want to share this video with them, I doubt they will listen to your video because it came from me... I know how busy these doctors are.

[@Medcram]

I really feel for you. It’s very frustrating to have a condition that nobody knows about or what to do. I think I’m going to look into this condition more carefully because I think there are things that we can do and I suspect that many of them are common sense things like getting outside fresh air sunshine and sleep. We need to stop preventing our body what it needs to do to heal itself.

[@laurabone3228]

@@Medcram Doc, I will post separately on this above some resources from specialists patients can take to their doctors. This as well is something you can build on that would be so valuable to your community. Bottom line is patients must become educated and bring tools and facts to their doctors to treat them. Long Covid, it is widely believed by experts, is just a renaming of a disease the CDC has tried to write off as a psychological condition for 30 years. Myalgic Encephalomyelitis. I'm following the specialty physicians and researchers in this space. Some excellent clinical tools / templates are available. Honestly a lot of testing is a waste because it won't change the treatment anyway. Enough is commonly known to occur to assume specific treatment protocols even without testing.

[@bettyjeanpetrinovich7373]

@@Medcram maybe this isn't the place for this, but besides sunlight and movement, I have found that another piece of the puzzle is foods. Each dynamic toward healing can be overshadowed by compromising dynamics, which is part of why healing can be so frustrating. "My" (anecdotal, observational, highly personalized) list of accessible, reliable, valuable resources for non-inflammatory dietary and life-style information: Two resources for comparing all information to: 1>>> kzbin.info/www/bejne/a4q5kJyBo993iMk Dr. Roger Seheult Light as Medicine... 2 >>>kzbin.info/www/bejne/Z2a1Y6ODprplpc0 Andrew Huberman, ophthalmology and neurobiology professor at Stanford; gut microbiome and brain health and overall health If advice that you view is contraindicated by information from Dr. Seheult or Andrew Huberman, give serious consideration as to whether or not the advice is reliable. Resources that I have used for guiding my diet to minimizing inflammation and auto-inflammation (mainly using the foods lists and limiting my grocery purchases to foods that these resources list): Eat to Beat Disease: The New Science of How Your Body Can Heal Itself - Dr William Li drwilliamli.com/ Foods To Eat On The Candida Diet www.thecandidadiet.com/foodstoeat.htm The 30-day Alzheimer's Solution - By Dean Sherzai & Ayesha Sherzai (hardcover) : Target www.target.com/p/the-30-day-alzheimer-s-solution-by-dean-sherzai-ayesha-sherzai-hardcover/-/A-80604319 The Plant Paradox Cookbook - By Steven R Gundry Md (hardcover) : Target www.target.com/p/the-plant-paradox-cookbook-by-steven-r-gundry-md-hardcover/-/A-53232020 (I use this cookbook mainly for the inspirational pictures accompanying the recipes, not as a definitive resource) If I purchase and use only foods from the food lists available here, I feel much better than when I "wander" off, in what I eat. Best wishes and blessings (vigor and vitality and propensity for life and living) to you in your pursuits of well-being and doing.

[@tigerspiritjourney]

Can getting near infrared light 'indoors' during cloudy winter days up north, be accomplished with an 1100nm infrared bulb? The red-light therapy lamp I'm seeing to buy is 300 watts at 1100 nanometers.

[@JK_JK_JK]

What?! Living a normal healthy lifestyle might be useful to be healthy?! Amazing! This was never mentioned once during the past 3 years...

[@StevenDragoo]

So adding nattokinase to help with micro clotting and quercetin will do the job and maybe even a small dose of melatonin at night... - More a question than a statement...

[@Kimm513]

I've had long Covid and now I've got Twitching In my right eye terrible leg pain in both legs. I have a lot of fatigue.

[@rica7611]

isn't Co Q 10 made in the mitochondria also known as the spark of life..love this doctor giving a great lesson without a shred of intimidating jargon..ty Dr.. hoping some day the Doctor can talk about what the correct definition is of anti oxidants..since I'm under the impression oxygen is vital

[@Medcram]

Oxygen is vital but oxidation is also the process of removing electrons. This can cause damage especially in the mitochondria. It’s why fruits are so vital as they are packed with antioxidants.

[@rica7611]

thank you Dr Seheult!!

[@olivia8979]

You haven't referenced red and NIR light devices (Joovv, Hooga, many others). I am sure real sunlight is best, but given it is cold and getting colder.... It isn't cheap, but I think red light devices are an option.

[@calluna5030]

I bought one a couple of weeks ago, having seen Medcram's videos on NIR . Thought it was worth a try. It has 2 NIR frequencies and 2 red light frequencies. I live in the UK. I've suffered from SAD the last few years but SAD lights didn't seem to help. For the last 4 years I have had neurological issues, muscle weakness, muscle fatiguability and generalised fatigue, and I've suspected mitochondrial dysfunction for some time as part of the problem. I'm sure the SAD is connected. (Neurologists can't give my condition a name, but say it is definitely neurological.) After I've used the lamp, and I use it primarily on my head, I can only describe it as feeling as if I have the sun in my head! I have my eyes closed, and at first get a small circle of little sparking lights - this gradually turns pinkish and becomes a bigger circle and the sparkles go and then it turns to a strong yellow. It feels lovely! I do a short session in the morning when I get up, and a slightly longer session in the evening. That lovely warm yellow feeling seems to stay in my head throughout the day, and I've noticed improving energy levels. Maybe it is just visual memory, or maybe it is actual change persisting over those hours? It is early days but I've noticed I'm sleeping more soundly too, though I've not really had any problems with sleep. I'm now feeling pretty confident that the lamp will help my SAD, and maybe the reason the SAD lamp didn't work for me was that it was missing those critical wavelengths. I did notice that a person had reviewed the same red/NIR I'm using but found it hadn't helped with her SAD, whereas the typical SAD lights did help her. So what works for one may not for another. The other thing that helped my energy levels a bit has been CoQ10. Having had a consistent healthy weight for nearly 40 years I started putting on weight and fat round my middle. Diets didn't reduce it, just reduced my energy levels further! Then I started on the CoQ10 and the fat literally dropped off me. From one day to the next I could see a difference. My weight dropped back to what it had been, and has stayed there. They do say that CoQ10 is needed to burn fat. In my case it certainly did.

[@olivia8979]

@@calluna5030 Hi, I also have one and have been using it since April or May. I believe it is helping me. It is just hard to quantify it. I can't know how I would feel if I didn't have it, but I believe it is making a difference. I have one that allows me to use it on about half my body. I use on my front and back about 5 minutes each. I open my eyes for about 2 minutes. It is supposed to be healing to the eyes. I have early stages of macular degeneration and have read that there are promising studies showing that it can help. I am eager to get my next thyroid test because I have Hashimotos and I gather there are also very promising studies about that. Anyway... good luck with it. I say do your front and back. A lot of people have neck and spine issues later in life. Maybe this can prevent that?

[@Krasbin]

Maybe going from incandescent light bulbs to LEDs is not an undivided blessing?