Making a liquid that attracts biting insects (1-octen-3-ol)

[@acside5313]

"It's naturally presented in both human sweat and breath" - so to avoid mosquito bites I just need to stop sweating and breathing. Got it

[@Azurath100]

Or use deet...

[@Azurath100]

@Jordann I can't believe that's already almost 30 years old... looks like dr. dre even made a new album.

[@every-istand-ophobe6320]

Only blm and antifa need to use that method.

[@omegabeast6847]

@@every-istand-ophobe6320 always find a way to be racist 😭

[@every-istand-ophobe6320]

@@omegabeast6847 yeah.. I took critical race theory classes and now I'm Racist and I agree with democrats and critical race theory that we should segregate. Crazy thing is I was never a racist until I voted for Obama. And now the liberals and Dems have pushed more racism than I have ever seen. Sad really.

[@sir9integra9jr]

I love how real you are--you always admit when you made a mistake, even if it's not visible or if it was a dumb mistake. I love scientists who make science seem more human, because at the end of the day, science is one of the most human things there is.

[@MrPbhuh]

It's actually very standard for chemists to admit mistakes, but it's more in the sense of lab journals and so on. You have to record everything, even your mistakes which does lead to a good practice, but usually most chemist's don't talk about their work outside of their circles

[@yaldabaoth2]

@@MrPbhuh Every chemist knows that a journal in which you publish mistakes would be far more beneficial for the craft than all those 99%+ yields that are never reproducable.

[@dushantrbovich5914]

51C to South Side 10st.

[@itzzy1859]

n.o.c

[@yakubtricknologist]

Science doesn’t exist I would know I made it

[@NovemberBegin]

Replace someone's bottle of bug repellent with this. ??? PROFIT

[@Decimated_By_A_Train]

Calm down, Satan

[@pinksapphire2898]

yess

[@blind1337nedm]

thats borderline date rape, no no.

[@Oliepolie]

NovemberBegin yes

[@shazamshazamski4490]

NovemberBegin I replace it with deer estrus. Now that is rape !!!!

[@mrchangcooler]

You should've made a little cup where insects can go in but not out, put a little 1-octen-3-ol in the bottom and left it outside for a day and then see if it's an effective attractant.

[@tjyoyo3]

It needs to be airborne, so misted with something like CO2 through a airstone. He was one step away from getting really good results, oh well, we get bitten by bugs all the time so we know it works...

[@francisbacon4363]

@@tjyoyo3 i love to torture bugs with electricity, cold andor hot water, fire, salt etc

[@ProfPuffOfficial]

Damn psychopath

[@floo1465]

@@ProfPuffOfficial bugs deserve it, the little fuckers. not bees or butterflies though, those boys are cool.

[@reverse7390]

@@ProfPuffOfficial shut up I hate bugs except the ones we need.

[@bcubed72]

Forget "Off!"...you've invented "On!"

[@mouthfulofchlorine]

This is the best comment I've read in my life.

[@beanlets]

Bravissimo

[@OkieDokieSmokie]

I don't care what the law says, spraying this stuff on people is a war crime.

[@scottydu81]

Mix this shiznit with some melted gulf wax and buddy you have an ON! candle

[@nunyabisnass1141]

@@scottydu81 add it to shampoo, cologne...

[@alharthy50]

Why do you feel disappointed man coz it's cheap to get online? . You made it yourself man, that's a big achievement in my honest opinion. Great video

[@JustinKoenigSilica]

yeah but he got a yield of 2%..... which isn't that great. at all.

[@zitronenwasser]

+ 70€ for that one needed thing

[@adityavarma193]

organochem really likes to fuck with yields.

[@tjyoyo3]

If he just bubbled CO2 through an airstone with this... he was literally SO close, the insects would have detected it in the air then.

[@ShepardJacob]

The fact that Nile described an Aldol condensation without saying a damn thing about “nucleophilicitiy, partial positive, nucleophilic attack on the carbonyl, pka,” and “alpha carbon chemistry” is beautiful. That’s how you know someone is brilliant.

[@大砲はピュ]

Wtf are all those words... 😆 I am taking HL IB chemistry... I should learn soon..

[@vladys5238]

a lot of the explanations in organic chemistry textbooks overcomplicate things for no reason making people think "Organic chemistry is awful and just memorisation" when for a lot of reactions the logic is quite simple

[@charl7508]

@@vladys5238 makes me think that it's worded in specific ways to make things seem more difficult than it really is, so that less people go into this field 🤔

[@vladys5238]

@@charl7508 i honestly think that it is because a lot of the teachers and people who make textbooks don't actually understand what is happening properly so they cling to set phrases and words . It's very sad

[@DragonBornGirl50]

@@vladys5238 as a chemist i agree with your words. Too much terminology and too little enjoying the learning. Also had to do with the fact that schools are businesses sometimes they dont teach things well enough, dont care.

[@Mattes_______]

Nile Red- the only Guy/Chemist on youtube who really pulls long-time project through. Respect for that dude! XD

[@googleeatsdicks]

NurdRage also does. He's trying to synthesize pyrimethamine. And chemplayer made piperonal from pepper.

[@Mattes_______]

yeah I know he isn't the only one :D I am just hyping him because I love his content

[@batubulgur]

Cody also does this pretty well. His projects are most of the times very different though.

[@kermichemgp]

really he he is awsome thanks to him

[@NileRed]

Thanks! :)

[@awsomesauce03]

i live in Africa, think I'll sit this one out gents.

[@FlatBroke612]

games i'm shit at mud huts don't make good laboratories.

[@RagbagMcShag]

@@notpulverman9660 yeah someone needs to take a good german shower

[@superturkeylegs]

@@notpulverman9660 Swedes were living in log cabins bro

[@sir.2015]

@@FlatBroke612 Lmfao omfg

[@StarGarnet03]

Australia. Beat that!

[@davidbarts6144]

"This bug spray doesn't work. It's not attracting any bugs." -- Morticia Addams At long last her wish has been answered!

[@IDonGiveAFuck]

I love this

[@whynottalklikeapirat]

“This baby oil does not work” - Swami M’Kubu, King of Cannibals

[@112048112048]

Garden: _doesn't get infested with biting insects_ Nile: My disappointment is immeasurable, and my day is ruined

[@kittyloveluvkitty7306]

Lol

[@TemereC]

an underrated comment

[@whynottalklikeapirat]

Underrated

[@a_true_generic_gamer1104]

Or, "This looks like a job for me"

[@DaciaSandero_1.5DCi]

F

[@colaptesauratus]

that moving shot was very skillful

[@tjyoyo3]

Codyslab: I'm not sure why my cameras moving on it's own...

[@frederikfelding8476]

It's really nice that you show and explain the reaction mechanisms. It really adds to the understanding about what's happening, rather than just "I pour some of this in, then this happens"

[@13arn]

You are amazing and though I hated chemistry in high school, you remind me why people might actually like this crazy stuff. Keep up the great work!

[@GiraffeFlavored]

Most people don't like science because they were taught it poorly, science sucks when it's just a bunch of giant words in a boring book and confusing diagrams with long, dry lectures. It generally tends to be a lot more fun in practice, chemistry basically lets you be like a chef only instead of making tasty foods you can make weird chemicals to play with and blow things up lol (safely of course)

[@Linkophere]

@@GiraffeFlavored its significantly more complex than you're making it seem. Chemistry is like knowing every single pokemon, thier moves learned at each level for each generation, when they evolve, egg moves, height, weight, foot print type, egg category etc etc. Chemistry is ludicrously difficult to learn at a usable level

[@majesticgopher115]

I honestly didn't think this video would come. A lot of videos saying "I'm making this chemical for my production of 1-octen-3-ol." But I didn't know if it would ever happen.

[@NileRed]

haha it finally did. It was a long and painful adventure

[@mrchangcooler]

Was it that difficult?

[@g00gdobb3ers7]

you must be new lol

[@KnakuanaRka]

Yeah, it took a while for that to come about. Didn’t help that his original plan was ruined by his acrolein polymerizing.

[@krap101]

proud of you. been working towards this for months

[@NileRed]

Thanks!

[@i_lift_marshmallows604]

I just took ochem 2 last semester and its so gratifying understanding the mechanism of the aldol reaction.

[@datpudding5338]

And once again you showed me that organic chemistry is way above my current state of knowledge

[@UltimateSugar95]

Damn, could've just extracted this from me. I can't seem to catch a break when it comes to bug bites

[@100GTAGUY]

Take some supplements that contain safe forms of Sulphur, down in Florida we had well water which had Sulphur and if you drank enough of it the mosquitos would mostly leave you alone.

[@UltimateSugar95]

@@100GTAGUY hey, thanks for the advice! I'll actually give that a try when camping season rolls around!

[@james_bond1869]

I actually had to draw the whole Aldol condensation mechanism on my organic II test yesterday. interesting to see it in use.

[@peculiar_wood]

I love how he always explains it like we are going to do it. There isn’t really another way to properly explain it WITHOUT sounding like a tutorial, but I still find it amusing

[@Tourist_ig]

Props to nilered's stirrer, it has been carrying this channel on its back

[@MM-op6ti]

I have been anticipating this video for a long time! Thanks for pulling though!

[@NileRed]

No problem!

[@mikechambers9129]

Hi, and thanks for all the vids. I hated chem when I took it 40 years ago, but I love watching your projects (and seriously lusting after your lab glass). This particular bid was timely because I just deployed a 40W UV lamp zapper about 4 weeks ago in an area saturated by hurricane Harvey floods. The lamp on its own is moderately effective. I looked at adding an octenol cartridge, but these are just ridiculously expensive. My further looking at some articles also made me skeptical than octenol without a sustained release CO2 source would provide much incremental effectiveness. Based on my reading and local observation of insect behavior, I've just deployed a decidely low tech next step. It's a 500ml bottle 80% filled with a 1:1:1 mixture by vol of sugar, scrap sweet wine, and water with a tablespoon each of cornstarch, flour, and dry baking yeast. The bottle is placed adjacent to the zapper. If this seems to increase the zapper rate, I might experiment next with adding octenol to the mixture. My thought process is as follows: while female mosquitoes are attracted to the CO2/heat/octenol produced by mammals, both male and female mosquitoes are attracted to sweet liquids (nectars) for nutrition. While only the females bite, they only bite after they've bred. Hopefully attracting the breeding pair near the light will reduce the actual egg carrying female population. Secondly, fermenting yeast seems to be a very strong attractant for many flying insects. Third, it's just a hunch but I suspect octenol isn't the only alcohol compound that attracts. I've observed flying insects attracted to glasses of wine, wine that has degraded to vinegar, and to bottled fruit vinegars. I'll try to post my results here. Meanwhile, if anyone finds a source for sub cosmetic/food grade octenol, please share. I can get a 40kg barrel from China, but a couple of liters ought to last my lifetime.

[@Schradermusic]

What are your results?

[@arda9437]

Just use mushrooms?

[@absinthe7266]

What are the results?

[@大砲はピュ]

What are the results?

[@brende.n]

what are the results

[@dannysullivan4904]

Could you mix this with candles wax?

[@user-or5cr4pn6m]

Calm down Satan

[@justintime112]

that would be a epic birthday present.

[@draganraus1976]

Yes

[@xXFangRideXx]

who hurt you

[@mwwq1]

That may be a good idea, depending on how typical use it

[@kailam5793]

Are you a teacher/ professor? Your passion bleeds into your teaching methods and it’s very engaging. I watch these for joy, and I wasn’t good at science at all. It’s the passion that keeps me watching.

[@bigdog4574]

You channel is wayyyy underrated!

[@misdafireinfexus5828]

I was gunna say what u mean but I said that 4 years ago Looks like got the attention he deserves!

[@swarnalathat314]

No matter what!! nile never gives up on a project....he works through it and gets results whether it's a fail or success he learns from it and also makes us learn tooo....kudos💕🙌🏻🙌🏻

[@maxobyrne1474]

3:10 “ooh” I think “I wonder what the mechanism for that is, I bet it would be cool.” Spend ages googling *”Now I’m going to break it down mechanistically”* “Ah for fuck’s sake”

[@NickWeissMusic]

I like that you put the reactions on cards, so I know when to fast forward

[@adriapacheco127]

The MPV reduction does not achieve incredible yields, but try to mantain all the reactants solved in the solution (you can try to continously adding the aluminium isopropoxide "solved") to the reaction mixture. If you maintain the products in the solution, you just have to displace the equilibria by distilling the corresponding ketone. You can also try with sec-butanol as a solvent, its higher boiling point may favor the reaction. The recovery of aluminium can be also made by using a saturated aqueous solution of oxalic acid, where aluminium oxalate/hydroxyde precipitates out during the phase separation. KEEP GOING!

[@salomeschliomkis7839]

I appreciate so much that you took the time to explain the mechanism of the reaction honestly, thank you, is cool to understand what's going on

[@levioptionallastname6749]

Boy,... This is EXACTLY what I needed.

[@WWsquared25]

@NileRed, insects can be attracted or repelled by semiochemicals based on its potency / concentration. Good luck on your continued experiments. It was a pleasure to watch your video. Thank you.

[@annabolicka4508]

Loved the video. You saying "the remaining XY is washed with a little bit of Toluene" is as soothing as Bob Ross saying "now we'll put a few happy little trees there"

[@puffy_btw]

i love how he allways says about following by a very exact number

[@spiderdude2099]

The way you said “incredible yield” always makes me laugh

[@HoneycombTheywontletmeputjusto]

angelic yield lmao

[@Hazed64]

It's channels like these that made me enjoy chemistry and physics in school. Keep it up 👍

[@twisty093]

Currently I'm going into grade 12 and hoping to follow through with chemical engineering afterwards (some thanks to you for extra inspiration there!) I assume these videos are more of a chemists hobby but what do you do for work? Keep up the awesome videos I'm sure you've inspired more kids like me!

[@twisty093]

@VoDx GT Currently in ~3rd year materials engineering as opposed to chemical. Taking my sweet time with my degree. No clue where I will end up career wise post-degree but I love thermodynamics and ceramic materials so something in that field I assume.

[@bhafferty5184]

@@twisty093 that's cool, is ben dover your real name?

[@KenzoKento]

As a 4th year chemical engineering student, I took an ochem class in second year and never used it again... 😂

[@sobertillnoon]

One of the most skillful moving shots I've ever seen.

[@Hartschteiler]

That moment when you look for the carbon in the Aldol Reaction and suddenly you remember.... but i had a few beers after work in my defense!

[@xiuxiu1108]

Thanks for inspiring me to review my organic chemistry, I'm taking up chemical engineering and I've already forgotten everything just 2 terms after my last organic chemistry subject. I seriously had to pick up my book and re-read about aldol reaction mechanisms. The alpha-carbon of one ketone attaches itself to the carbonyl group of the other carbon in basic conditions

[@saadanwar99]

16:43 😂THE STIRRER IS POSSESSED 😱😱

[@diegocrescente8785]

Thanks God!!! Finally the most expected video! What an amazing and loooong work-out! MANY CONGRATS

[@Josiahhhhhhh]

He mentioned making the metal smelling 1 octen 3 one in this video, about 3 years before he made a video on it. That’s kinda wild.

[@natalie4900]

I usually hardly understand these videos, but this one was exceptionally beyond what I know

[@owololcat]

Nile: *bringing up all kinds of chemicals that I know nothing about* Me, who's just here to see the potion maker do miracle stuff: I like your funny words magic man

[@addiewylie3813]

OMG I have been waiting on the edge of my seat for this video!!! Im so happy !!!!

[@KakashiBallZ]

Save your Patreon money for a rotavap!

[@NileRed]

I actually already have one. I just dont have space for it!

[@KakashiBallZ]

Damn that's too bad lol.

[@coleramsey6705]

+KakashiBallZ Too bad? He owns one! I would take one, but I don't have the space either.

[@coleramsey6705]

+KakashiBallZ or the money

[@KakashiBallZ]

+Cole Ramsey too bad he doesn't have space...

[@masterofdoctory]

best camera sweep to show a setup I've ever seen. and sloppily much product. lol . love the humor

[@AureaPersona]

Hey Red, I got an idea for a video I'd enjoy seeing. I recently read that _n-halosaccharins_ can act as convenient substitutes for n-halosuccinimdes in some reactions. From what I've read I think they could potentially be quite useful to us hobbyists due to their versatility, ease of preparation and favourable safety profile. I'd love seeing you try to replace N(X)S with the corresponding halosaccarin in some halogenation reaction.

[@25Killer]

Your videos always help me fall asleep. I adore your voice and the interesting content behind it. Be safe 💜

[@crtfit9792]

I've been marathon watching your videos ever since you replied to my comment today lol. Thanks for replying by the way

[@farklestaxbaum4945]

This is the stuff that comes with bug zappers, there are little fabric tabs that come with it, soaked in octenol, that supposedly attract bugs to the zapper.

[@samlabo1688]

I want to spread a ton of this in my brothers yard when he throws a party

[@Preinstallable]

calm down satan

[@dovahdog0]

go on satan

[@ConsoleQAQ]

I think this was mentioned in a later video but the dehydration step in aldol condensation follows an E1cb mechanism, which means that after the acidic proton is deprotonated on the beta-hydroxy ketone, the negative charge again moves to the oxygen of the ketone, then reforms the carbonyl and the double bond by pushing of a hydroxide. You can probably think of it like a reverse 1,4-conjugated addition.

[@BAgodmode]

“In my next video, we will make a chemical that attracts air horns and people who still aren’t over firefly being canceled.”

[@spacecase13]

At 18:38 This answered that question I always had about the smell you get when touching metal.

[@andrewdavis5386]

What were the reasons that 1-octen-3-ol was believed to be an attractant of biting insects before the research showed that there was no major difference between traps baited with it and traps not baited with it?

[@Zarosian_Ice]

Well form what I understand it's the same sent humans give of that attracts insects/mosquitto's so, even though they do the same the point was attracting them with a scent that they follow naurally, also, the report says that it would be a lot more potent if you combined both the trap and the 1 octen 3 ol together

[@tjyoyo3]

When bubbled with CO2 it becomes misted/airborne, making it a airborne scent for those pesky bugs to find. much better then just coating a trap with it.

[@a_guy4363]

Everyone else in the chat: ⚡️🧠⚡️me: POTIONS

[@Menagerie_OS]

I mean if its safe next to a current, slap that stuff on a bug zapper 😂

[@Sleepy-Kun]

I have no clue what he's saying nor understand it but I like listening to him talk about science XD

[@JoshuaRando]

Wow that smell of metal on my fingers... That is really interesting. Talk more about that soon. :D

[@skydyverjym]

The ONLY person I've ever heard pronounce toluene correctly. My chem profs didn't even bother doing that

[@plastiqueneurosis]

This would be perfect to wipe on my enemies clothes during the summer.

[@thecarrasius]

I thoroughly enjoyed watching the whole process (precursor videos too). Feel a bit sorry for you and want to give you a big hug,. Even if you didn't attract any bugs in the end, it was all worth while because of the great videos. :)

[@alllove1754]

Woe to company who doesn't hire you

[@n0binobs]

the videos this guy make is the only thing I enjoy watching even if I can't understand it

[@phosphine95]

Don't you think that using column chromatography would be better to fractionate reaction mixtures than vacuum distillation? Btw nice channel, a lot of chemistry knowledge is coming from your videos 😉

[@meyus.mp3]

I dont understand most of the things. But still enjoy watching it. Thanks.

[@Eat-Glass]

I wish I showed up to chemistry so I could know what he's talking about. Still interesting tho

[@Cisconnotthesinger]

Man I’m so grateful he has a camera man now.its a total different show with the camera man

[@Battlefox64_RL]

I'm a moron 😅 but I still enjoy watching and trying to understand the reactions taking place.

[@2.5rs_subaru]

Same lol

[@sovietunion2095]

Why do I hate science but love watching science on this channel????

[@AliHSyed]

whats your education​ background? bsc, mSc?

[@NileRed]

BSc biochem

[@Rhodanide]

That adapter is so clever!! Good video. :)

[@Schism07]

5:15 your intermediate is a beta-hydroxyketone in the diagram, but you said it's an aldehyde, or am I missing something?

[@lablulz2483]

I was confused about this too.

[@defaultminerlp4433]

That is correct, he made a mistake there.

[@ZivTheWyrd]

finally. been waiting forever for this!

[@adityavarma193]

for around $80, I found 1000 grams of 2-heptanone on sigma aldrich. It was 98% pure

[@RBuckminsterFuller]

You've gotta be attached to an institution or a company to order stuff from them and I don't know if he's allowed to order reactants for private use through his workplace... I'd reckon the answer is no.

[@dascandy]

NileRed Inc. you mean? Sure they would ;-)

[@jakelancaster5889]

dascandy Hm Is. That an actual loophole? Not that anyone can do of course

[@tjyoyo3]

propane -> butanol -> 2-heptanone

[@manuelbonet]

At last!!! I have been waiting for it!

[@MegaKittens12345]

STOPCOCK

[@Videohead-eq5cy]

When he tries to go for the butt

[@newhampguy]

👀

[@notpulverman9660]

😤😡

[@paramedic79ca]

Thanks for showing the mechanism!

[@nickalgiere8280]

1:05 (anhydrous)

[@poonamkushwaha]

Congrats. Been waiting for this.

[@ZRTMWA]

"To show the whole apparatus, I used a very skillful moving shot." k

[@triplebarrelbrainexposer]

I don't know what this guy is talking about but I like it

[@BadBoiFX]

In highschool they teached us how to inject poison into nuts to kill squirls

[@spinn4ntier487]

JQuery I didn't know they taught chemistry to downies

[@vaishnavishivkumar7593]

its so cool to see reactions we learn in school actually being used!

[@jdflyback]

Mercury distillation all with glassware would be cool, I have on seen it done with metal retorts.

[@NileRed]

I plan to do it in glass

[@slabbulkhead6875]

This would be really good to use as bait for a bug zapper or large scale outdoor trap for mosquitoes. Could really cut down on bugs around the house

[@QuintonRC23]

CO² attracts well enough. I'd say this would be unnecessary.

[@dannahbanana11235]

Just what I was looking for. There are entirely not enough biting insects around for my taste. Great recipe, thank you.

[@AE_RECORDS]

Real-life Senku. Great job man.

[@zubmit700]

Very interesting. Keep em posted buddy

[@UKinQ8Gaming]

These OG videos are way better than shorts. I have no idea what he is talking about. Im sure these videos benefit people studying, i just watch them because science is amazing. I feel like you could make some kick arse vodka. Let me know when nile red vodka is available. Id buy it!

[@amkamomega]

For checking for acetone, you could have used sodium nitroprusside if you had some lying around. If present, deep blue colour is observed.

[@nipz8053]

12:41, and what a skillful moving shot it twas...

[@tichu_pietribiasi905]

I dont understand anything he doin but i could hear him talk for hours

[@8cto289]

Step 1: cover a piece of c4 with bug attractor and meat Step 2: wait for all biting bugs in a 5 km radius to form a giant pile over the c4 Step 3: detonate the c4 remotely Step 4: enjoy the outdoors without getting Lyme disease, malaria, and/or West Nile virus!

[@isleofdead1337]

“Aye yo chuck us the mosquito repellent” “Yeah… sure”

[@realmanners17]

So that's why mosquitoes are into me