Making Benzoin

[@Josezwitterion]

Very interesting thanks love for organic chemistry

[@mixery_dose5435]

If you don't have thiamin, you can also use other thiazole (5 Ring with a N and a S) containing compounds. Thiazolium salts (like vitamin b1) are frequently used as a less toxic alternative to cyanides in the stetter reaction, which is similar to the reaction shown in the video. The catalyst (cyanide or thiazolium salt) changes the polarity of the aldehyde so it can attack another aldehyde like in the video or an alpha-beta unsaturated ketone like in the stetter reaction Source: The heterocycle lecture I'm writing an exam about this thursday

[@yourfuneral]

I like the mentioning of a non-KCN-way with Thiamin! Looking for that non-toxic hard-work stuff :D Thanks for putting in the structural formulae :)

[@timezz]

The structure looks like A-PVP

[@Jawst]

0:01 my first thought was scrambled egg 😂 there are some really interesting reactions when cooking food! I would love to see you do some cooking with a breakdown of what's happening in your awesome style 😎😋

[@reformlabs8742]

Slowly approaching 10K I see!

[@jimparsons6803]

Slick prep. Thanks for the hint about mp apparatus. I've tended to use mp tubes, but a test tube would work, and it's cheaper. Like cheaper. For those that are interested, flavors and aromas are still a big deal, could be that they always will be. Natural products and all of that. There's this story that I once heard about a Chemist and his kids during the 20s and 30s supporting his family (quite well, thank you very much) by extracting citrine and other materials from orange and lemon peels that had nightly discarded from restaurants in NYC and then taking those garbage items to his lab in a walk-up in Harlem. The reason that I recall this story is that for a while there he was the only person that owned a pick-up truck. What, not funny enough for you? How about instructive?

[@SciGuy700]

hey why don't you make benzillic acid from from it...

[@THYZOID]

already did that, filmed it and even fully edited it

[@experimental_chemistry]

I made it with the help of thiamin, but the product is nearly white and not that deep yellowish like yours - maybe caused by a sideproducts which decrease the purity? Btw.: it smells quite nice, but by far not that intense like other aromatics, dibenzalaceton for example.

[@THYZOID]

my recrist was trash. otherwise it would be purer

[@experimental_chemistry]

My product wasn't yellow at any step. Maybe your KCN wasn't pure enough if it was selfmade stuff. I would really recommend thiamin instead.

[@stevengill1736]

You should never stick your nose so close to a chemical, use your hand to gently waft a little towards your nose first! It's a good habit, avoiding a burned nose in cases of mire corrosive chemicals.... Also, a couple drops of tincture of benzoin improve the performance of the blue bottle experiment....cheers.

[@THYZOID]

benzoin isn´t toxic so I don´t care about smelling it directly

[@mikeltxo11]

How would you describe the smell? Really curious about it now

[@THYZOID]

like benzaldehyde but without the "almond" like smell... smells are hard to describe man

[@mikeltxo11]

@@THYZOID Thanks! I think i got the idea...haha. Yeah, experiences are difficult to put into words

[@fburton8]

Scratch’n’sniff merch? 😜

[@WaffleStaffel]

I have some natural benzoin (styrax - balsamic tree resin) and it has a thick, sweet, spicy smell. It was traditionally used as incense. Wonderful for burning on an incense heater.

[@AelwynMr]

@@WaffleStaffel Yes, but natural benzoin resin is mostly benzoic acid, and no benzoin at all, if I'm not mistaken :)

[@leothecrafter4808]

How did you make the cyanide? Did you make it yourself. You've been putting it off for so long maybe I've missed a video, but did you make it or buy it?

[@THYZOID]

made it myself. you don´t want to know how many methods I devised and tested to make cheap, highly pure cyanide

[@leothecrafter4808]

@@THYZOID I could think of a lot of methods like the ammonium formate route or using a safe complex like potassium ferricyanide and acid and it would all have in common that you'd have to bubble HCN through base which isn't the safest way. I wonder how you did it but I don't know if YT will allow you to show us.

[@THYZOID]

@@leothecrafter4808 I tested most methods you could possibly think about but I won´t show any of this on youtube. The safest and easiest route turned out to be one of the best ones. It only needs one reagent and a solvent for the purification.

[@tonyflamingo3285]

I did this twice but my mixture never turned that red. And I cleaned it just by rinsing with cold water in the funnel. The ir showed it was pretty clean. But I got a pretty bad 60 percent yield.

[@hiddenbear5306]

Using potassium cyanide is the chad way. Using Thiamine is the safe way.

[@ingensvidcz5390]

could you oxidize it to benzil and then react it with chloroform to make some cool sort of chlorinated alcohol? Dunno, more like asking; bit that could be cool.

[@THYZOID]

I already used up all of it

[@homocapensis7854]

Buenísimo .

[@abidhasanonib9032]

How to make KCN? (NH2)2CO + CaO --> Ca(OCN)2 Ca(OCN)2 + C ---> Ca(CN)2 Ca(CN)2 + K2SO4 --> KCN Isn’t it the right way? I wanted to synthesize prussian blue and Lactic acid 🤷‍♂️

[@THYZOID]

There are much easier ways. I´ll show one on my odysee channel soon

[@abidhasanonib9032]

@@THYZOID waiting ❤️ Also can you find a way to extract oxalic acid from wood sorrels. These chemicals are not available for me or too much high price.

[@bfgoalie99]

@@abidhasanonib9032 i've seen oxalic acid online as a wood bleaching agent sold by the pound. Maybe outside of USA is different though

[@mihirsanghvi9876]

@Thy Labs Can you pls make a video on the synthesis of Acrolien???

[@THYZOID]

maybe

[@puo2123]

I did this to test my self made cyanide :)

[@FullModernAlchemist]

Can you share with me your source for benzaldehyde? I can make it easily but I have been wanting a pure sample to compare with my efforts.

[@THYZOID]

check the video description.

[@SodiumInteresting]

Next step aniline? Maybe I'm thinking benzamide for that

[@ivant5054]

how does it smell like? this compound is 100% a byproduct of a very easy and high yielding reaction to make benzaldehyde from cheap benzyl alcohol (with dilute nitric acid and sodium nitrite catalyst) it absolutely does make benzaldehyde, but it also makes benzoin, would be interesting to know if the smell is bitter in any way since that's how my freshly made un purified benzaldehyde smells like

[@THYZOID]

the smell is vastly different from benzaldehyde. hard to describe though

[@Antonio-qm3bi]

Bro can you make Acetophenone? I've heard it smells like roses, but I don't have acetic anhydride to make it 😂

[@zodiakofficial4093]

Acetophenone does smell fruity, but I wouldn't say, that it smells like roses. If you want something, that smells like roses, than 2-Phenylethanol is exactly, what you are looking for! I made mine from Benzaldehyde -> Mandelonitrile -> Mandelic acid -> Phenylacetic acid -> 2-Phenylethanol But Synthesis of Acetophenone is quite easy. Just do friedel-craft-acylation of Benzene with acetyl Chloride. Or If you want the otc-way then mix Benzoic acid (food preservative), acetic acid and Calcium hydroxide (hardware store) with a minimal amount of water (to get mixed calcium salts) then perform a destructive destillation of the dry material using lots of heat. But cleanup of the product will probably be a mess^^

[@igotes]

Will the reaction still work if we don't spill some of the solvent on the table?

[@THYZOID]

no catalytic spills onto unsuspecting furniture is necessary.

[@sonogashira3376]

whats the smell

[@THYZOID]

like benzaldehyde on steroids but without the almond smell

[@1brytol]

I don't know why you used cyanide. You can use thiamine as a catalyst.

[@1brytol]

Cyanide is a really old and obscure method, which isn't really used right now

[@THYZOID]

I prefer using toxic reagents if this means the yield will be higher. besides that I don´t see any reason to buy thiamine if I already have cyanide

[@1brytol]

@@THYZOID understandable

[@1brytol]

@@experimental_chemistry yeah, don't eat cyanide

[@SuperAngelofglory]

I love the smell of the end product, but I rather not work with cyanide. Good job!

[@dontworry4945]

0:38 mentions that it is dangerous and should not be handled. Me: cool. 🤓 0:50 me looking at the little drop that snuck out 👀💦

[@NBK-ro4sz]

How to hydrogenate at home? Is it even possible?

[@THYZOID]

it is. there are plenty of videos on youtube detailing how to easily hydrogenate

[@NBK-ro4sz]

@@THYZOID what about high pressure hydrogenation? Around 100 psi or more

[@chanheosican6636]

Nice compound.. yes nurdrage said to work with Kcn you need a ba in chemistry.

[@THYZOID]

you don´t need a ba in chem you just need to not be stupid while working with extremely dangerous chemicals.

[@mgrzeg]

Try to synthesize cyclohexanone cyanohydrin - also great smell of menthol ;)

[@chicken1117]

10g KCN 😳😳😳

[@THYZOID]

yeah next time more will be used

[@SciGuy700]

​@@THYZOID 😂😂 hates small batches

[@loganosmolinski4446]

Boop