Sensitivity and Specificity Explained Clearly (Biostatistics)

Understand sensitivity and specificity with this clear explanation by Dr. Roger Seheult of www.medcram.com/?Y...
Includes tips on remembering the differences between true positive, true negative, false positive, false negative, and other statistics, as well as the overall effect on clinical lab values. This is video 1 of 1 on sensitivity vs specificity.
Speaker: Roger Seheult, MD
Clinical and Exam Preparation Instructor
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
MedCram: Medical topics explained clearly including: Asthma, COPD, Acute Renal Failure, Mechanical Ventilation, Oxygen Hemoglobin Dissociation Curve, Hypertension, Shock, Diabetic Ketoacidosis (DKA), Medical Acid Base, VQ Mismatch, Hyponatremia, Liver Function Tests, Pulmonary Function Tests (PFTs), Adrenal Gland, Pneumonia Treatment, any many others. New topics are often added weekly- please subscribe to help support MedCram and become notified when new videos have been uploaded.
Subscribe: kzbin.info_...
Recommended Audience: Health care professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NDBE, RN, RT, MD, DO, PA, NP school and board examinations.
More from MedCram:
Complete Video library: / medcram
Facebook: / medcram
Google+: plus.google.com/u/1/+Medcram
Twitter: / medcramvideos
Produced by Kyle Allred PA-C
Please note: MedCram medical videos, medical lectures, medical illustrations, and medical animations are for medical educational and exam preparation purposes, and not intended to replace recommendations by your health care provider.

[@kirstenroche8160]

I have tried to learn this concept about 100 times in medical school. It never made sense to me. Your one short video talking about cars has somehow completely driven this concept into my mind! Thank you SO MUCH!

[@MuhammadJunaidAshraf]

I have an exam in a week and I couldn't understand the the SPIN and SNOUT thing so I searched Sensitivity and specificity explained intuitively and this came up. Not disappointed, it explained so much. Thank you.

[@alphavirginis260]

This is, by far, the best explanation of Sensitivity and Specificity! Thank you!

[@brianjackson4177]

All of your videos are great. They are concise, well planned, and effectively communicate the concepts! Thank You!

[@pcookieness]

Speaking my language, you used the perfect examples and methods to teach this!

[@cili5724]

OH MY GOSH this actually makes sense finally! As I write boards, here I am Once again trying to learn this! Thank you! You’ve done it!

[@RohanKayani]

Beautifully explained. A must know lecture before reading medical research articles.

[@burakORAKC]

this was fab thank you so much. Your title is just what I found in the video "EXPLAIND CLEAR" meaning we have a true-positive (TP) :D

[@annetteasbury7415]

Wow, you made it so much easier to understand than our professor. Great use of the analogy of the car alarm. Thank you!

[@SubhabrataMoitra]

Brilliant explanation. Could you make a video on sensitivity and specificity with a real-time example? A drug-disease interaction would be great.

[@victoriacarter9892]

Amazing as always! Your videos take difficult concepts and make them very simple and easy to understand. I absolutely love your channel. Thanks for doing what you do! :)

[@Medcram]

+Victoria Carter Thank you for the feedback!

[@jcleach2764]

This was by FAR the best breakdown and explanation I've come across. Thank you!!

[@saraamin8154]

Thank you :) ! You always have wonderful explanations.

[@jakirhossain8409]

a lot of thanks you make the things so easy

[@ORagnar]

Thanks for this video from 6 years ago. What makes this concept clear is to realize that there is noise you're trying to contend with.

[@user-om9jv9om8f]

Yes, it's really clear in explanation. Thank you so much!!

[@Medcram]

為主作工 good to hear- thank you

[@MrKoolguy9]

Excellent explanation with lucid examples ... awesome !!!

[@toddmason1865]

Excellent video from an excellent physician. I worked with Dr. Seheult for several years and I can say he definitely knows his stuff and has a great voice and ability to explain clearly, no doubt. Thank you doctor it helped immensely.

[@Medcram]

Todd Mason Thank you Todd, great to hear from you

[@pohsstudio7769]

Great analogy with the car, makes it so much more simpler!

[@mateuszkaczmarek9848]

Best video on sensitivity and specificity, great job!

[@nichols44nancy]

great video...hope you will go on to part 2 :)

[@saileshbalanagu7530]

Thank you so much! Its very clear now.

[@petesburgher]

thanks for the explanation ... I get it now!

[@badr985]

where is the second video for the mathematical interpretation part ?

[@AjaySharma-pg9cp]

Explanation provided is quite good

[@ericlipnack4175]

thank you, great explanation

[@salam7905]

that car example has clarified everything I was confused about .. thank you so much ^-^

[@moe1n]

Excellent. after many years I got my answer. Thank you .

[@Bekah07]

This is fantastic.. thanks so much. When is the next video in the series going up?

[@ankursatya4733]

Quite explanatory and the car example was chosen "specifically".

[@terigopula]

That was a nice explanation. Cheers! :)

[@niharikadharmapuri8343]

well explained! thanks

[@00bean00]

The interpretation I made: Spec. is the number (or %) of negative cases it _accurately_ rules out. (Negatives) Sens. is the number (or %) of cases it accurately _identifies_ . (Positives) Thus, for any given test there will be a gap (or %), which is the number of cases that cannot be accurately known, or, are _unknowable_ (as FP or FN).

[@nazmaahmed1544]

Really helpful. Thank you

[@DrMilanii]

Great video! Can you please explain IV fluids in clinical practice? Thanks a lot

[@b.kwanmin3367]

This is brilliant !

[@Mrseabase1]

Thank you for the video. It was helpful.

[@Medcram]

Glad it was helpful - thanks for the comment

[@AbdullahMQ]

Great video, but does any one tell me where is the following part about the mathematical part?

[@bodybalanceanneloes9666]

Thank you for this great explanation!

[@DeepBlueMuslim]

Thank you, simple explanation for what is a relatively difficult concept. Think i struggled due to my understanding of the words 'specific' and 'sensitive'

[@Medcram]

+Omer Elhassan Thank you for the feedback

[@radwaandjama923]

You sir are an absolute legend. Couldn't't have explained it any better. Thank you!!

[@PiyD2537]

Very Well Explained...!

[@cortis77]

This is the best video I could find explaining sensitivity and specificity clearly, THANK YOU!

[@kayaksta]

excellent Roger!

[@bobolob]

Helpful, but when you got to the bell curves, it was hard to visualize TP/FP and TN/FN because you didn't actually label them under the curves. If that makes any sense. You filled the spaces in, just no labels.

[@DreamEclipse]

That's because it's very hard, he would have to draw it three times. But for reference, if the test is equally sensitive and specific (point B), the half of the curve on the left is the TN, the half of the curve on the right is the TP, and the bisecting part in the middle from left to right is the FN and FP.

[@tomtong9859]

Brilliant video!

[@FaisalYami]

really good !!!

[@nothodube3698]

Great stuff. Simplified👌

[@Med.School.Survival]

Great presentation :)

[@rockernoobsthurein]

Cool bro! Great job!

[@Princesscamiii]

I love you! I will always refer to disease as "thief" and test to "alarm". hehe

[@miladchenaghlou5278]

Excellent !!!

[@amirrezaeterafi3959]

Fantastic! thank you sir

[@otacon3d]

At the end of the video it says there's a "next video" Still waiting on a part 2, will it still come? Also can you explain positive and negative predictive values?

[@FlyingFlaneur]

They released another one. kzbin.info/www/bejne/kIHGZ5KLoMmnsLc

[@naghmeazadi8294]

Great as ussual.Thanks

[@nnp418]

Hi, I am confused about the cutoff point for most of the true positives, the highest positive predictive value, the lowest negative predictive value and the highest specificity on graph. At what point, I get most of the true positives and at what point I get the highest specificity. I hope someone clarifies these. I would be much more appreciated.

[@ednamayseymour2053]

THANK YOU!!!!

[@hlulanisambo1933]

Thanks

[@reneeshortz3404]

still a bit hard to grasp but I think I'm on the right track now!!

[@AballVR6]

I love your lectures!!! Could you do one on neuro?

[@mechanizatorius]

next video??

[@vdp5837]

Thanks!

[@Eric-sq4hd]

we need this for npv. and ppv too

[@AK.ALMAHASNEH]

thank u so much bro God bless you

[@pammyholisticmed]

I appreciate the misspelling... I'm not alone! Evil e-i combos. THANK YOU for this video...

[@Medcram]

+Pam deWilde Thanks for the comment, but what is the misspelling are you referring to?

[@pammyholisticmed]

MedCram - Medical Lectures Explained CLEARLY : Forgive me, I meant to reply to the comment below. At minute 2:50ish, the word "Thief" is misspelled. The last person to comment made mention of it, or I wouldn't have noticed. This video was very helpful, truly.

[@Medcram]

+Pam deWilde No problem at all, thanks for letting us know, and apologies for the misspelling!

[@helenhayes3298]

What is the next video called please? I can't find it

[@oodon3220]

thank you!

[@neard89]

please upload next one...

[@arnabsaha3006]

excellent...

[@zarsblackhorse123]

Thank you.

[@syedwraza6184]

Great simple easy

[@Gossypol]

I have understood 50% of the video. But after 6:21 the next part was a bit confusing for me. Still for the 50% a thank you won’t be enough. But still thank you very much. 🤚

[@bhaskergowda2203]

Could any one solve my problem or come a cross this problem pls let me know I have got trigenomial neuralgia from 17 yrs and I have been taking tegretol for all these years now lately l have developed sensitivitiness in leg and arm l cannot touch cold or hot water cannot walk longer pls help

[@Eric-sq4hd]

finally makes sense. wow..

[@leezanewill-cordington8395]

What is and why do tests have a "pre-setting"? 🤔. Take the covid-19 testing, could it be that the prerequisite for identifying the virus is highly similar to other viruses, thus giving false positives?

[@misanteojos5934]

Thanks for the video its awesome, the car example is genius! but theif!!! makes my eyes hurt! hahaha

[@chiragmehta2955]

If population is on y axis,What is on x axis?

[@narjesseghatoleslam5307]

Dear Dr. Seheult, I did two different test for detection of a bacteria in the same population. Is it possible to calculate PPV, NPV, Sensitivity and Specificity of each test Separately with out gold standard ? Could you guide me please. Thank you for your consideration and confirmation would be appreciated. Sincerely, Narjes

[@Medcram]

+Narjes Seghatoleslam in order to calculate Ppv and npv you need to have accurate info on disease. This requires a gold standard.

[@narjesseghatoleslam5307]

Dear Dr. Seheult, thanks a lot for response, it is very nice of you.

[@Olu_Segun]

Brilliant

[@dr.ghaith]

great thanx

[@boyuanchen4997]

Came here from Jeff Heaton's Machine Learning course :)

[@rayanhasnat2140]

I think, sensitivity= TN/ TN+FN And specificity= TP/ TP+FP

[@ioannisdikeoulias]

Specificity = TNR and Sensitivity = TPR...you mixed something up at your explanations 9:48 ...still good video!

[@khankhan-cw2bq]

Dont understand car eg make it more difficult...

[@daradangana5625]

Thankssss

[@Stonefalconetti]

Thief written "theif" and you are obviously a Native English speaker.. Yes, you really must be a very good doctor!!! ( No sarcasm. It's true. :))

[@johnweir1217]

Really good but I before e except after c. 😄

[@Runcible2010]

Because of the epidemiological fallacy, test sensitivity should be high regardless of any demographic factors.

[@bhupensinha3767]

FP and FN aren't correctly put .. interchange em...

[@Medcram]

+Bhupen Sinha false positives are people who don’t have disease but test positive. They go in the right column and top row by definition. False negatives are people who have disease but test negative. They go in the left column bottom row by definition.

[@dr.osmanelamin77]

Great :) Thanks alot

[@imeann...]

6:00

[@joshuahornick3221]

"Thief", not "Theif." Still, very clear. Thank you.

[@طبيعى]

High Sensitivity low specificty

[@Yazan-Baki]

Greeeeeeat

[@monicaherrera-rickman3704]

👌🏻👌🏻🙌🏼🙌🏼👏👏

[@janicebaker3499]

Spell thief correctly please

[@joeymatee]

lmaooo

[@Medcram]

+janice baker yeah I know. "Thief" there!

[@carog4969]

Get out of here

[@ryezizzle]

unwatchable video! jkjk!

[@swngstr]

What’s a boombox? Ha ha jk.

[@themossman77]

Thief not theif....👌

[@LD-pt5ur]

I like your tutorial. I hate the car alarm example.

[@Bj0rken1984]

Thief ;)