Bilirubin Metabolism & Jaundice - Gastrointestinal (GI) Physiology & Pathology- Physiology Series

Biliverdin, Bilirubin, Bilinogen Metabolism & Jaundice (Hemolytic jaundice, Hepatocellular jaundice, Obstructive “cholestatic” jaundice…Prehepatic, hepatic, posthepatic jaundice | GI Physiology
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[@MedicosisPerfectionalis]

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[@dr.fernazmbbsmd44]

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[@MedicosisPerfectionalis]

@@dr.fernazmbbsmd44 Dear Doctor! First, thank you for subscribing to tier 2…Your support means the world to me! Second, try doing so on your desktop computer (you can also try a different web browser). Here’s my email if you need anything: [e-mail] I can’t wait to hear your opinion on my 300+ Premium Videos! I am really grateful to you!

[@kitsunefire92]

Not sure if your intended audience includes Medical Lab Tech students but I appreciate these videos none the less.

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Lab tech here!!! I binge watched so many Medicosis videos during school…I still do sometimes for a refresher ❤️🫡

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@@MirandaLovesPathology they're so good! and they help me so much!

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Hi , I'm a lab technologist and working on my channel to help others out, do visit my lab house if you want! 😃⭐

[@nooralhoda8529]

It's been a week since I've searched for your jaundice video 😅, I'm happy that you've posted it today 😍

[@MedicosisPerfectionalis]

Hope you enjoyed it!

[@waelfadlallah8939]

If the stool is not brown we need to talk, if it floats we need an appointment and if it's pencil-shaped we need surgery!😅 Great explanation encompassing all bilirubin related pathologies 👍

[@MedicosisPerfectionalis]

Thank you 😊

[@antonyshigin4977]

My favourite physiology channel: Medicosis perfectionalis

[@MedicosisPerfectionalis]

Thank you so much, Anthony!

[@Dr_strange_2652]

My best online teacher I am lucky enough to get ur classes in online....❤❤❤❤❤❤❤​@@MedicosisPerfectionalis

[@0xApollo]

You make me call pathology a babyyy Thanks so much 🙏🏻 💓

[@MedicosisPerfectionalis]

My pleasure!

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How talent you are at interpretation staffs in scientific way.

[@MedicosisPerfectionalis]

Thank you!

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Honestly you are a rare gem ❤

[@MedicosisPerfectionalis]

Thank you so much!

[@احمدصادق-ك8غ]

Thank you so much medicosis, follow your videos from egypt

[@MedicosisPerfectionalis]

Thank you 🙏

[@shafiqkassim_]

never imagined myself laughing and learning medicine. BIG UP MEDICOSIS

[@MedicosisPerfectionalis]

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[@aasemahsan]

13:52 Jaundice 18:47 Pre-Hepatic & Post-Hepatic Jaundice comparison 21:44 Comparison among Pre-hepatic, Hepatocellular & Post-hepatic jaundice 23:41 Congenital Pathologies

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So far the fav channel ❤

[@MedicosisPerfectionalis]

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[@alanwaterman1328]

Yes it all makes perfect sense with your words of wisdom.

[@MedicosisPerfectionalis]

:)

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Love this ❤

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Great explanation

[@MedicosisPerfectionalis]

Thank you 🙏

[@pashenw5519]

congratulation for 1 million 😁

[@MedicosisPerfectionalis]

Thank you so much!

[@Dr_strange_2652]

Hey medicosis Please make a live session with us As we can see you directly.. don't know why i feel great connection with u medicosis. I never have so passionate and caring teacher like u ever in my life😢😢. I don't know if i get the opportunity to meet u or not! But its my belief that i will get the opportunity to meet u somewhere inshaAllah.. please sir if possible please have a visit to Bangladesh..... Take care and keep sharing your wisdom Sir

[@lanaalfares8350]

Thank you so much I appreciate your effort to make this masterpiece (mastervedio) جزاك الله خيرا

[@MedicosisPerfectionalis]

I appreciate you!

[@sanahameed4205]

U r my real life hero....thank you for existing ❤

[@MichelleDespres]

Wondering if you could discuss this process with no gall bladder and also extremely low iron... I'm having infusions.

[@gironkid8303]

I LOVE YOU MEDICOSIS

[@MedicosisPerfectionalis]

:)

[@tinghuanhsu3469]

it's awesome !thank you

[@MedicosisPerfectionalis]

My pleasure!

[@naaengmann2117]

really helpful!

[@MedicosisPerfectionalis]

Thank you so much!

[@gironkid8303]

❤❤❤❤❤❤ saving my grade ❤❤❤❤❤❤

[@MedicosisPerfectionalis]

I am honored!

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Thank you so much

[@MedicosisPerfectionalis]

You're most welcome!

[@mahimapearlin7432]

Talented sir❤❤❤❤❤

[@-Emune]

Not joking i opened the PDF given to us by the professeor and it is legit this video in slides 🤣🤣

[@MedicosisPerfectionalis]

Wow! I appreciate you so much! Side note: Your wonderful professor never asked for permission or even said thanks!

[@sarzievlog]

please don't skip ads..

[@tiss]

Very informative video... Thank you

[@MedicosisPerfectionalis]

My pleasure!

[@moinn230]

Please make video about hepatitis ❤

[@shamskadhim4188]

Brilliant 🤩

[@MedicosisPerfectionalis]

Thank you, Shams! Would you please help me by sharing?

[@shamskadhim4188]

@@MedicosisPerfectionalis sure 🫡🤍

[@MedicosisPerfectionalis]

Thanks!

[@mitanshusharma5944]

Itss Just Awsumm. Toooo Goood.

[@MedicosisPerfectionalis]

Thank you!

[@shinn-tyanwu4155]

Great 😊

[@MedicosisPerfectionalis]

Thank you so much!

[@grahamsmith5768]

I had jaundice, and it was a wake up call to look after my liver.

[@shashishekhar----]

Good video

[@MedicosisPerfectionalis]

Thank you 🙏

[@ivymatimati]

Weldone this is short ñ simple

[@MedicosisPerfectionalis]

Thank you so much! Would you please help me by sharing?

[@tmsff9893]

1- the urobilin and Urochrom are the same? 2-In hepatic and post hepatic what does make the urine dark if there is no urobilinogen?

[@qamar997]

awesoom❤🎉

[@MedicosisPerfectionalis]

Thank you 🙏

[@LeahRebecca]

ty

[@MedicosisPerfectionalis]

My pleasure!

[@anastasia1431]

I literally manifested this video 😂 God bless you

[@MedicosisPerfectionalis]

God bless you too!

[@lolo-dv4yi]

19:10 How obstructive jaundice can be intrahepatic? doesn't it confuse with hepatocellular jaundice?? Thanks for this greatness really❤️❤️👏

[@aureliavruzhaj3191]

beautiful

[@yomnahabashy3254]

‏‪ ‏‪10:39‬‏ Famous Egyptian professor.. Dr Nagi ❤❤❤

[@thehigherevolutionary]

Thanks!

[@MedicosisPerfectionalis]

Thank you for your support!

[@okk2101]

Great!

[@MedicosisPerfectionalis]

Thank you 🙏

[@lolo-dv4yi]

How is stercobilin produced in hemolytic jaundice? It is preheat defect so, it can't reach intestine so, urobilinogen isn't produced and it is produced from oxidation of urobilinogen?? I wish I didn't misunderstand😢😢.

[@ibrahimgalal9136]

10:40 د/ ناجي اسكندر

[@MedicosisPerfectionalis]

Yes!

[@reh303]

As someone with autoimmune hemolytic anemia, this was very informative. Thank you.

[@MedicosisPerfectionalis]

Thank you! I wish you the best!

[@shahadaljouf8638]

My question is the bilirubin greenish color cuz our doctor said it’s colorless but once it differentiates in the intestine it gets the color and in urine it will be colorless

[@mohsenahmed1270]

Amazing 🤩

[@drdurdana3668]

Why stools are dark in hemolytic anemia plz clear it reason behind it??

[@kzthluv5598]

Because of increase in the total amount of urobilinogen

[@kira01982]

Guys, I have a question ❓ I have jaundice from time to time with lower dried lips and feel sleepy most of the times. I did CBC test and all was normal except my bilirubin was way higher than peak ,the liver enzymes were OK as well POINT : I FAST ALL DAY ONLY TO EAT AT DINNER , is this common or related to liver damage?

[@AAtkinson]

Sounds like Gilbert’s Syndrome. It’s a common genetic condition which leads to elevated bilirubin due to an enzyme deficiency of UTG1A1. Affects about 10% of Caucasians. When the body is under stress the liver produces less of this enzyme. Lack of sleep, excess exercise, dehydration, emotional stress. Fasting is a type of stress. I bet if you stopped fasting and drank more water the jaundice and bilirubin would normalize, or the bilirubin would be only slightly elevated.

[@shubhamparande6002]

Hey even I am dealing with same. My cbc test all was normal but sgpt was 125 . Can anyone help me out pls

[@kjasalewjathan]

Is jaundice the same as scleral icterus

[@MedicosisPerfectionalis]

Scleral icterus is a symptom of jaundice.

[@fatimamaryam3168]

Hi I have a question, if due to obstruction bacterias are not able to form urobilinogen and stools are pale then how the urine colour is dark, as urobilinogen has to be converted to urobilin and excrete in urine?

[@MedicosisPerfectionalis]

The urine is dark because of conjugated bilirubin.

[@ValentinaKajcinovska]

Should urine always be yellow, mine is non colour at times. I call yellow bilirubin..

[@moinn230]

Thx bro❤

[@Ahdbfbfbeh]

How many liters of bile do we make per day or expect to drain into a tube?

[@hello-un8gh]

In hemolytic jaundace shouldn't be the urobilinogen in the urine increased? Both CB and urobilinogen in the urine give coca cola like appearance?

[@mariama.sgodhelpme2264]

The Egyptian professor is he Dr Nagy Iskandar ? 😅 I think i heard him saying the same way from many years

[@MedicosisPerfectionalis]

Yes!

[@عمادزيتاوي-و1ف]

Big like 🌹

[@MedicosisPerfectionalis]

Thank you!

[@yanbingzhu2550]

Hi Medicosis, if the patient have hemolytic disease of RBC, doesn't their hemoglobin ends up in the urine and cause hematuria? Therefore, the urine will be red, full of hemoglobin? Why did you say the urine will be normal color?Thank you, medicosis.

[@MedicosisPerfectionalis]

There are 2 different types of hemolytic anemia (intravascular and extravascular). I was referring to extravascular hemolysis. You referred to intravascular hemolysis. Moreover, the video is concerned with the effect of bilirubin and its metabolites on the color of the urine, and not the effects of other factors.

[@yanbingzhu2550]

@@MedicosisPerfectionalis I see. Acute hemolytic transfusion reaction must belong to the intravascular hemolytic anemia. RBC got killed and bursted by IgM antibodies in the blood vessel. The spleen macrophages probably did not eat those RBCs. Is Rh incompatible hemolytic disease of new born intravascular or extravascular? Do you have a video talking about the differences between intravascular and extravascular hemolytic anemia? Thank you so much.

[@ideal1402]

10:41 Prof naji ❤

[@MedicosisPerfectionalis]

Indeed!

[@darrenj.griffiths9507]

As always, bloody amazing 👏 (excuse the pun). Thank you!

[@mahmoudhassan6934]

You are slightly affected by dr Nagi 1973 Chole conjugate Ca contrac And many things Watching you after him Best wishes from Egypt

[@mahmoudhassan6934]

I comment before this 11.6 Feeling proud 😊 Their is Egyptian teaches medicine concepts very well with brilliant accent even for American students.

[@abdelrahmantarek7713]

هو مصري

[@abdelrahmantarek7713]

شوف اكتر فيديو مشاهدة عنده

[@mahmoudhassan6934]

@@abdelrahmantarek7713 مصري ايوا كان بيخمي تجربته علي الفيس أنه بدأ يشرح كدا من ايام كان بيذاكر رمد في مصر وكان في ريل هنا لما كان بيتكلم عن thalathemia قال إنه مصري

[@Abdullah10466]

Who is the famous Egyptian professor ?

[@mayflower2904]

I love you

[@MedicosisPerfectionalis]

Thank you!

[@ivymatimati]

❤❤❤

[@MedicosisPerfectionalis]

:)

[@drsidhant11]

could jaundice be more simplified, no! ❤

[@Dr_strange_2652]

Hey perfectionalis Please make something easier payment system like DR.Nazeeb. as we from Bangladesh can't enroll in ur courses due to lack of credit cards. You can make a deal with some Bangladeshi online payment pages who help in payment... Please medicosis, help us in this wayyy❤❤❤

[@Dr_strange_2652]

❤❤❤❤❤

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Hi how are you love from jess x

[@MedicosisPerfectionalis]

Thank you!

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Can you reduce your subscription money . Im from India and its expensive for me

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Just go the site and buy it from there

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In love with you ❤

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🎉🎉

[@MedicosisPerfectionalis]

:)

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[@MedicosisPerfectionalis]

🙏

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Wilson Steven Johnson Laura Taylor Dorothy

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😅first

[@MedicosisPerfectionalis]

Thank you 🙏

[@أسامةالعوامر]

Are you Egyptian?😅😅😅

[@ubaidullah1611]

Awesome lecture

[@imeann...]

I cannot express how much this helped me. Really really grateful

[@meloukabelalia]

thank you but how conjugated bilirubin will increase in the blood in hepatocellular when the liver can not conjugate bilirubin !

[@ThinleyMbbs]

Sir doesn’t Alp increase in hepatocellular jaundice??

[@danielsima882]

Is there a chance that, direct bilirubine can regurgitate back in the liver (in cholestasis) and affect the conjugation process in healthy hepatocytes and therefore the indirect bilirubin gets to raise too a little bit?

[@jacenite8517]

Sir please I’ll like you to go a bit deep into creatinine, lft and rft with practical applications so I can prepare before exams

[@Dr_strange_2652]

Another boss level explanation ❤❤ Greetings from Bangladesh

[@MedicosisPerfectionalis]

Glad you liked it!

[@Dr_strange_2652]

@@MedicosisPerfectionalis always liked boss

[@hishamabu1170]

❤❤❤❤❤

[@ABC-fv7ow]

Superb🎉

[@MedicosisPerfectionalis]

Thanks 🤗

[@jacenite8517]

25:16 Sir please I’ll like you to go a bit deep into creatinine, lft and rft with practical applications so I can prepare before exams

[@MedicosisPerfectionalis]

Check out my “labs” playlist.

[@Dr_joona]

Thankyouu so much👍👍👍👍👍👍

[@SomaDler-cy4we]

Thank you.

[@hamzaalghurbani]

I love that famous Egyptian prof 😂🤍🤍 Two hearts one for him and the other ... 😂