Molecular docking | Introduction to basic computational chemistry method | drug-target interaction

[@scienceaddicted3431]

I hope this video is useful for you. Please let me know if you have suggestions, ideas, or need for some of the next videos topics. Thanks for visiting the channel. Let's keep the discussions going!

[@BasicScienceSeries]

Indeed! Let's support and take the science to everyone around the globe free of cost! Looking forward to seeing more videos. Thanks!

[@scienceaddicted3431]

Thanks you for the support! Due to my day job, my time and energy is very limited, but I'm working on the script for the next video! Can't wait to have it finalized!

[@screechza]

going bald tryna understand this by myself. Shoutout to my kowalski buddy for showing me your vid!

[@fatineaissani7123]

Thank you for the simple explanation

[@scienceaddicted3431]

So glad you found value in my video!

[@thedigitalchemist5757]

thank you , the video is very useful after watching this video things started to become clear for me.

[@scienceaddicted3431]

Wow, so glad i could help

[@ahmedboshaala6849]

Thank you , very good information.

[@rashamoustafa427]

Great lecture 👌 😊❤❤

[@sadidmorshed8363]

This is literally Helpful.Thanks a lot for sharing ❤️🥰

[@RehanKhanPRK]

Very informative video 👍 Thanks

[@scienceaddicted3431]

Thank you for the encouraging comment! Glad the vide was useful

[@chandanaranga]

Simple and precise...good information 👍

[@scienceaddicted3431]

Thank you so much for watching. I'm glad you found it useful.

[@chandanaranga]

@@scienceaddicted3431 keep doing such videos...they are really informative...I was searching for docking videos but haven't found a single one which is precise and simple...but yours really given a quick insight into the topic

[@scienceaddicted3431]

@@chandanaranga That is really nice to hear and will certainly motivate me to finish the video about practical tips in docking. This method appears to be simple and accessible, but there are many ways to mess it up and get artifacts without realizing

[@screechza]

anyway, what's your thought on the new SwissDock with AC2?

[@BasicScienceSeries]

*Valuable information! Thank you.*

[@scienceaddicted3431]

Thank you! Glad you found it informative.

[@benjaminewilliamcordez5195]

Thank you for this!

[@saptantoputra7937]

Searching suitable key for specific lock 🔐 using algorithm and scoring

[@scienceaddicted3431]

Thanks for your comment! Hope you found the video useful.

[@br353]

Thanks you

[@scienceaddicted3431]

Thank you too for watching!

[@نرجسمحرمی]

How can I download these animations for my presentation

[@Myri912]

Great video, a curiosity...what is the program have you use for the slides? thanks so much

[@scienceaddicted3431]

Thank you! I have used kdenlive video editor and animation to create this.

[@samuelaina4861]

Hi, I'm from Nigeria, I will like to learn more about computational chemistry at large can you render any help towards this?

[@ximenaramirezvelasco7139]

❤❤❤❤❤

[@mahamafzal8108]

Hi ..can u answer me few confusion.. I took protein id from pdb database but it in their is no Ligand present in it.. How we know to docked particular ligand with protein.. Please get me out of confusion...

[@scienceaddicted3431]

Hi! You can check multiple structures in pdb, to see if there is any with ligand included. There is an Advanced Search option, where you can filter and refine your search. In case you don't know the binding site on a protein, there is a docking technique called blind docking, where you can search and scan for binding sites on the entire surface of a protein.

[@scienceaddicted3431]

Thanks for watching and let me know if my answer clarified your confusion!

[@محمدالداهري-ز7ق]

hi , i need for he[p in molecule docking can you help me please

[@agila19]

which software is used to find small molecule-small molecule binding interaction...?

[@scienceaddicted3431]

Hi Agila, there are many, but I most frequently used autodock and autodock vina

[@agila19]

@@scienceaddicted3431 thanks, but autodock is used to find the binding between macromolecules + no of small molecules right..?

Hey there! What's your name? I am using your video for my undergrad presentation (with credits) and I'd like to cite your name and educational background =) Thank you

[@scienceaddicted3431]

Hello Ursula! That is amazing, thank you! Also happy that i was able to help in any way. Please email me at Science.addicted at gmail and i'm happy to provide details

[@ggezwpgjnpgaming2186]

I'm a Pharmacist who is interested in drug to herb interaction studies using in silico methods. Do you have an email address where I could ask for help and more questions? Thank you! This video is an effective tool for learning. Thank you so much!

[@scienceaddicted3431]

Hi Ian! welcome to the channel. I'm glad you are interested in _ in silico_ methods. My email address for this channel can be found in the About section. Please write me there, and I'm happy to respond as time allows.

[@ggezwpgjnpgaming2186]

@@scienceaddicted3431 will do. Thank you so much! Keep on making videos!

[@scienceaddicted3431]

@@ggezwpgjnpgaming2186 actually I'm just about to record the voice over, for the next video. Should be ready next week!

[@ggezwpgjnpgaming2186]

@@scienceaddicted3431 I'm excited to see that then. Keep up the good work!

[@mahadxalane3552]

good lesson dear teacher can we have your email

[@scienceaddicted3431]

Happy to help at Science.addicted at gmail