NAD+ and FAD+ Cofactors

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[@davidcastillo5623]

You taught me more in 9 Mins than my chem professor in a whole quarter

[@Jagopei97]

I'm from Spain but I understood everything well. Great video my friend I had dudes about this but they are now resolved

[@MakoKong]

Finally, a lecture on nad that makes sense and that you keep track of. Great video

[@AKLECTURES]

Jeff thanks! :)

[@nellyhoffman6194]

Man you explain better than my professor of biochemistry ! lol

[@GoodbyeRubyTu3sday]

Correct me if I'm wrong, shouldn't the reactant in the reduction reaction of FAD be FAD instead of FAD+? Is the + not correct? Because otherwise the reaction doesn't make sense

[@saadmohamed4769]

YOU ARE RIGHT

[@leaamira7996]

So much better explained than any german video

[@mattphorwich]

Great video! Inspire and educate! God bless the multiverse!

[@carryon5021]

Thanks, the speech was direct and easy to grasp.

[@rizamkhan2143]

Nice explanation

[@saram7586]

this guy is the real mvp man!

[@NikkisTemptation1]

I love your videos they help me revise concepts going into post grad. However, can you please discuss the role that magnesium plays in this? It doesn’t seem to be clear in any teachings anywhere!

[@nellyhoffman6194]

Thank you ak lectures !

[@alyaasaad433]

You are a great person 👏👏👏👏

[@damianokoroafor8497]

The reaction FAD+ + 2H+ +2e- ===== FADH2 seems wrong. The net reaction comes out to be FAD(+)H2.

[@bobtheman50]

I think you are correct. My biochem text has the reaction as FAD + H+ + H: = FADH2, where H+ is a proton and H: is a hydride ion.

[@fazeel147]

You're soooooo beautiful Damian

[@danielstacey2660]

I think the error comes from the original molecule charge. The FAD+ should actually be just FAD, without the +. Then it just accepts two neutral H atoms basically (One proton and one electron from each)

[@arpitabanerjee7665]

thanks for all the great videos. u made biochem easy!!

[@danalasa]

rookie question incoming: why do we need FAD+ and FADH2 if we have NAD+ and NADH?

[@ioNicholas]

I had the exact same question the first time I learned this. I think it has to do with the differences in their redox potential. High energy hydrides can be released for large amounts of energy with NADH but this is not always the ideal scenario. In some instances less energy is required for a particular metabolic step so FADH2 can be used to release an amount of energy which more precisely fits the needs of that step. If we only used NADH then we would be releasing more energy than is necessary at times. If anyone has a more precise answer feel free to elaborate or correct me.

[@oogenesis12]

FAD can transfer single electrons (or two electrons), NAD+ can only transfer 2 electrons

[@EducatorSharmin]

Amazing class!!!

[@SissouwChan]

Everything makes sense to me now, thank you! :)

[@duhaarshadshaker3951]

Thank you so much ❤️❤️❤️❤️❤️

[@goji8430]

Should I be taking NAD like Niagen Nicotinamide Riboside or NDAH? Which one is better to take?

[@dellah8656]

FADH2 is synthesized in protein complex one?? Is that an error?

[@ASD321XYZ]

Naa in Complex 2, where no hydrogen ions are pumped (the only complex that doesn't pump hydrogen ions out of the 5)

[@AFGPride2332]

This is Golden!

[@AKLECTURES]

Hasib Haidary lol thanks! :)

[@elanomiguel4698]

My question is Nad and fad always binding to apoenzyme. OR can be exist in free form without binding to apoenzyme

[@prational]

Excellent lecture! Thanks

[@AKLECTURES]

You're welcome Phil!

[@SuperLika17]

great video

[@sciencenerd7639]

thank you

[@rennierennie321]

Thank you sir. But, are they not coenzymes?...(organic non-protein part)

[@gracehutahaean3306]

Could you help me explain this? Actually how many H+ that NAD+ accepts? I also read there is anothet equation : NAD + 2H+ + 2e --> NADH + H I'm confused 🙏

[@donnam4730]

lol who is this person!!!! so easy to understand!

[@fadeskywards1245]

What's your age, man? Great explanations btw

[@blastbangblast]

Very good explanation indeed :)

[@AKLECTURES]

Souvik Das thank you!

[@amandagarza5050]

Please make more videos for vitamin metabolism!

[@Ricardo-jg3jf]

So if NAD supplementation makes sense does FAD supplementation make sense also?

[@willyt2357]

Thank you sir!

[@abbagarba641]

thanks a lot Sir

[@sabbyschannel1293]

thanks so much!!

[@AKLECTURES]

You're Sabina :)

[@averybrennan3216]

Fairly certain that NAD+ is a coenzyme

[@cloudmintswirl1169]

did anybody else get ASMR feels from watching this?

[@liviankasiraja5670]

very useful . thanks :)

[@AKLECTURES]

Livian Kasiraja You're welcome Livian!

[@raxmaibrahim3166]

helpful thanks

[@BraianaDiaz]

amazing

[@davidanderson8778]

so is this witnessed in human subjects, is it verifiable?

[@shilpaaswal6469]

Sir pls make a video on fMN nd NADP+

[@whatdoyouknow4843]

Where are you from.... I can't place the accent?

[@krestenhermansen1260]

Is FAD+ and NAD+ cofactors? I thought it was coenzymes.

[@qehc]

Coenzymes are cofactors

[@saram7586]

wicked man!!!

[@sabretoothed99]

FAD needs boron as a cofactor

[@MrNerveux]

"and when we PAHMP EM"

[@abeersh8541]

I don't understand how reduction of NAD to NADH 😭

[@danielstacey2660]

The incoming high energy "package" consists of three things: H+ and TWO electrons. The first electron is used to reduce the original NAD+ molecule to NAD. The second electron is used to reduce the H+ to H. Now the NAD and H can join to make the product (NADH). All electrons have been accounted for.

[@yagmurcamd]

Progress.

[@martinushjrungnes9542]

Bro relax please

[@mariamali1190]

ليش ماكو ترجمة عربي -،-

[@whatdoyouknow4843]

Where are you from.... I can't place the accent?