Nociception 2 of 4: C-Fibers and Motor Effects

  Рет қаралды 15,686

NeuroDocUniverse

NeuroDocUniverse

Күн бұрын

Пікірлер: 9
@NeuroDocUniverse
@NeuroDocUniverse 12 жыл бұрын
Hi Almas. Interesting thought... Because the muscles involved are essentially segmentally related intrinsics, I wouldn't expect a brain issue. A brain issue would more likely affect larger muscle groups or spinal regions. C-fibers are being activated by cellular degeneration of every structural component of the hypomobile spinal joint. Intracellular fluid is released in the extracellar space, which causes the C-fibers to depolarize.
@lucasvlta
@lucasvlta 9 жыл бұрын
What are these literatures that you say in the video? Could you reference or cite these literatures? Thank you.
@bigmaristuff
@bigmaristuff 10 жыл бұрын
Would mobilization of the the hypomobile joint tend to reduce the depolarization of the C fibers ? I read somewhere that the facilitation of type 1 & 2 afferent fibers such as Muscle spindles, Golgi Tendon Organs , Pacinian corpuscle's etc. have the effect of "reducing" the depolarization of nociceptors in general whether the be Type A or C. If this is in fact the case how then can we apply this knowledge to break the self perpetuating cycle of hypertonicity,hypomobility, and finally degeneration.
@NeuroDocUniverse
@NeuroDocUniverse 10 жыл бұрын
Hi Mario, Yes, depolarization of proprioceptors can diminish the processing of nociception. There is a video on this channel that discusses the pain gating process.
@bigmaristuff
@bigmaristuff 10 жыл бұрын
NeuroDocUniverse Thanks for your swift reply. I will check out the video.
@xHaniffax
@xHaniffax 10 жыл бұрын
Maybe I missed something - I understand the cycle but when does this get registered in the brain?
@NeuroDocUniverse
@NeuroDocUniverse 10 жыл бұрын
Hi xHaniffax! Thanks for your question. The cycle described is completely subthalamic and the neocortex is not involved. The entire reflex system can occur without pain.
@xHaniffax
@xHaniffax 10 жыл бұрын
Thank you for responding so quickly! I see. :)
@NeuroDocUniverse
@NeuroDocUniverse 10 жыл бұрын
Hi :-) The c fibers are wired to the brain. The predominantly synapse in areas below the thalamus (subthalamic), so pain doesn't usually register from this reflex. I hope this helps!
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