Neurology | Basal Ganglia Anatomy & Function | Direct & Indirect Pathways

[@mimiboobies]

I don't think you know the impact you have in our lives. Some of us would not be able to reach our goals if it wasn't for you. The way you explain this very complex subjects with such an ease is really remarkable. May you be blessed for all the work you do, You sir are gifted and we thank you for all that you do! I know you can do so many things with your talent, but PLEASE don't stop making this videos!!

[@mhlorenzo]

See, people do wish him well!

[@Comrade_Sergei]

Me and my med school classmates thank you from the bottom of our hearts as we're currently in the thick of our neuro block and have found your neuro videos very helpful.

[@dranthonyasturi9790]

I and my med school classmates would do well repeating high school and learning the difference between object and subject.

[@kabeerthaker4727]

@@dranthonyasturi9790 what you meant to say was "My med school classmates and I..."? Hopefully they'll teach syntax as well ;)

[@bentenyson6570]

@@kabeerthaker4727 ok boomer

[@fairpurenature]

I am a neurologist. This is the best explanation and tutorial I ever came across. Much better than ANY med school. Unbelievable value. Thanks so much. 😀

[@ernestopanza4194]

I'm an MS2, this guy is nuts isn't he lol. I'm going to destroy my exams and I'm not sharing this with anyone until after lol.

[@EIonsMusk]

@@ernestopanza4194 don’t be a gunner…

[@ernestopanza4194]

Witholding info doesn't make me a gunner. Sabotaging someone else would though@@EIonsMusk

[@sanafsanaf7933]

Dr najeeb

[@antoinettegoosby]

The fact that I’ve followed you since my prenursing days and now I’m in graduate school working on my masters in neuroscience and your videos are still helping me.

[@antoinettegoosby]

Also side note. I’m pretty sure you gave me a tour of penn state a long time ago. Were you an ambassador there?

[@alih6953]

Dear Zach, I want to thank you for all the hard work! I hope every desire of your heart gets granted! You are awesome!

[@myplaylist3859]

Thankyou well wisher may god also fullfill yours

[@alih6953]

@@myplaylist3859 God bless you

[@giuseppelernetti8667]

You are Grest.

[@mhlorenzo]

Funny, every time I watch one of his videos, I wish him happiness... and feel curious about whether he is in fact happy. I certainly hope so.

[@ameisha2471]

I’m in medical school and the lectures in class make no sense but you make it simple. Thank you so much for this. Please donate to this guy!

[@happyboy7144]

😂😂😂he is just amazing

[@johnstillman2935]

probably because you lack a brain

[@patrickblackwell777]

You're one of the best teachers I've ever come come across be it the internet or otherwise. Thank you for being an invaluable resource for students around the world!

[@metronidazole5681]

Your neurology lectures giving me boost to build career in neuro science. Thank you so much

[@jenessalemon6848]

Covering this in med school now with a really...challenging professor. Life saver! Thanks.

[@sanahassan4867]

same

[@qixinzhang1648]

This video about basal ganglia is amazing! I get clear details and a whole picture of these three complex pathways at the same time! Fight on! Dr. Ninja!

[@marcellachmely5206]

My 2 year old thinks you're Dwayne The Rock Johnson

[@bassam4965]

😭😭😭😭😭😭😭😭😭😭😭😭😭😭😭

[@wencca3062]

based

[@chottabacha1705]

It's too good , he will learn very much things

[@harishchad.]

​@@chottabacha1705chota bacha🍼👶

[@ratneshr_mehta]

Do show him/her these videos, who knows next Einstein is in your home 😂😂

[@amelonlord654]

Everytime you smile and say something is "cool" or "interesting" it makes me remember one extra thing or process:) Thanks

[@debadritaraha2462]

The details you dive into, the lucidity of your explanation, you make med school all the more interesting. Don't think I could ever thank you enough.

[@yoanadenkova4335]

The amount of help these videos provide me as a med student in Germany is crazy - i have never found a more helpful lecturer on KZbin

[@lukadangadze8283]

I barely meet such a talented people as you. Your explanations are very excellent and very helpful for every medical student. Keep going! 🙌🏻❤️

[@meetgandhi8202]

The feeling you get after knowing a concept is unmatchable. Thanks to you sir.

[@yamamasajed6341]

Hi Zach, it’s 3 am in Czech republic and right now Im struggling hard with my pathophysiology exam and im here just to tell u that u helped me a lot AND without u i would never had reached my goal. So Thank you a lot❤️

[@MD-ot8ff]

Yo can we get a ninja nerd shirt that says "Fire like a mofo"? 😂Super helpful vid! Thank you!

[@eugenemourimaileopold2868]

I need one of that shirt too 😂😍😎

[@TheLabutterfly1]

Excellent explanation, you're a gifted communicator and teacher. Thanks for this.

[@djstax28]

Zach my man you are an absolute time and lifesaver and I seriously mean that. I've been scouring the internet to understand the direct/indirect pathways and never seemed to get it. I even watched my professor's 90 minute lecture and still did not understand it. Then I watched like 20 minutes of your video and I have a complete understanding. Thank you for all that you do!

[@garrettdyess1110]

So good. Allows a novice to understand the concepts in an easy and natural fashion. Thank you.

[@xtecco4752]

Note-taking on this video was assigned as homework for my high-school anatomy class. I have learned more in the first 20 minutes of this than I have in any of our two-hour lectures.

[@Mikesco10]

high school... that's pretty impressive most people here are med students or students in other health-related specialties

[@daianesoethecoan8572]

There's no words to explain your tallent and dedication. I was trying to understand this a couple days, and you made it feels simple. THANK YOU SO MUCH

[@besttiktoks4352]

Even a study hater like me willing to engage myself in study after seeing this guy's video. I mean wooooh man

[@joudizawet7573]

Words can't thank enough ")❤ I really can't imagine studying physiology and neuroanatomy without your videos this semester ⭐⭐⭐

[@mohab_68]

This is totally one of the coolest, most awesome, mind-tickling physiology lectures I have ever studied, with your great & easy explanations I really can't thank you enough for this ❤️

[@grishagautam2517]

Why is substantia nigra inhibiting indirect pathway and causing an increase in unwanted motor activity....in the last pathway??

[@Maissablm90]

Sameeeeee questionn!!!!!! If someone know pls tell meee

[@rashadomara1628]

i think there is amistake in sequencing of pathway

[@its_rachel1]

HONESTLY speaking, your videos are the first thing I search for if I have difficulty with a topic! Thank you so much Zach 💕

[@gabrielavecchi]

PERFECT CLASS! I'm at psychology school and in my university i've never had such a class. It's the first time I undertand neuroanatomy

[@EIonsMusk]

I pay $48,000 a year in medical school.... you explained this in a way that was more comprehensible than any medical school likely has. Bravo!

[@LoylaDemiseem]

That username tho 😂

[@gpetaluma]

In a land where patients may sometimes have to manage ... doctors or medication ... your little video classes expand ones understanding to the point a little power is obtained! Thanks Zach!!

[@neelo14]

The way you teach Dr zach is amazing.I fall in love with medicine. Thankyou so much for your good work.

[@jessicaqian7527]

I cannot express my gratitude enough. You explain things so clearly!! Thank u!!!

[@duhaal-qaderi689]

You don't know the impact you have in my life! Thank you dear Zach!

[@tjvh493]

So much respect for your teachings. As person who never had the oppertuinity to study Neurology, this certianly helped me with my self studies, thank you thank you thank you.

[@margarytamaksimtseva2322]

I love how excited you are about this complexity! 'They are going to fire like a mofo' LOL! THANK YOU

[@cecesarinana1272]

I don't think you know the impact you have in our lives. Some of us would not be able to reach our goals if it wasn't for you. The way you explain this very complex subjects with such an ease is really remarkable. May you be blessed for all the work you do, You sir are gifted and we thank you for all that you do! I know you can do so many things with your talent, but PLEASE don't stop making this videos!!

[@Priya_Dutta]

Thank you so much! This demonstration is really very helpful and one of the best illustrations out there. I have my Neuroanatomy exam in two days, and this video helped me clear my confusion.

[@tanurathore4664]

The way you explain everything in such an easy and interesting manner is just amazing!! Thankyou so much sir😊

[@ياسرطارق-ح6ح]

We appreciate every moment you give us with your wonderful videos. Thank you so much zack

[@Top_G.609]

Man you are my hero. Your neurology playlist is awesome. You have helped me cover topics that were alot more difficult for me to understand.

[@nicole9007]

Basal ganglia topic finally made sense to mee. Will always support this channel and will not skip ads! Thank you Zach and all the ninja nerd team! You're all blessing to med students. The best teaching style! :))))

[@chithoyip684]

It is a very awesome video!! I am occupational therapist and I learned a lot from your channel. School may not teach these medical stuffs in such a detail. It really helped me to understand more and train my patient.

[@professor_shao]

I hope neurology lecture series won't end without having a video on traumatic brain injury and management😚

[@Ellen5e]

Same! TBI and manifestations of damage would be a particularly interesting series. 😊

[@louis9833]

You literally are saving my degree - thank you so much I cannot actually put it into words!! When I graduate as a doctor I will remember to donate to your channel as you've helped me sooooo much :)

[@daniellakallicharan3457]

Literally have an exam on this tomorrow, thank you!

[@rashmishrestha6487]

Best of luck 👍

[@lammihownishylla2637]

Me too☺️

[@andrewmaleto-uz5bu]

This particular one is a master piece. Thank you Zach

[@abelincolnparth]

Best presentation ever of basal ganglia I have seen/heard/read in my 30 years as a pharmacist.

[@gigachad8961]

I’m having an exam next week and the best lecturer just posted the main subject of it, Big Heart ❤️

[@kisakyejemmynyanzi3830]

I love the simplicity, you give us to this anatomy

[@sherifabdelhalim5912]

The way you explain such complicated subject is phenomenal. You are talented and gifted. Thank you

[@brenogoes7920]

Dear Zach, I'm from Brazil and I have to tell you how grateful I am for your hard work! Thank you so much!!!

[@TanzeelaNawaz-r5c]

feeling really relieved after listening, realizing myself that yes their are some specials who are always their for you not to worry always their to help you teach you and light you when you really need them. you deserve more than a word of thanks but what can i do is just the word thank you.

[@liabevilaqua3305]

Hi Zach, yours sure is one of the best explanations about this subject ever!

[@aspirant4759]

I can never imagined understanding neurology with this much of clarity..but you made it possible ❤❤

[@SelomieTeklay]

So many of us would probably have given up if it wasn't for your videos. I can't even begin to explain the impact you have on my life. THANK YOU Zach!

[@peytonstaab4424]

Your videos are SO helpful as I'm going through my med school neuro block. Thank you thank you thank you, you are amazing!!!

[@Nicole20397]

This video was so excellent. I've alway struggled with neuro material and all the structures that lie within the cerebrum and what they do. This by far one of the best lectures on the basal ganglia I've ever seen. I finally get it know. Thank you for everything you do!

[@bethelihemtakele3211]

you don't even know how much you popped me up thank you so much

[@neuropsychologist]

That is literally the best visual explanation of basal ganglia I have ever seen! Genius. Life changing. A big thank you to you and your team 🧠 ❤

[@jadeykins28]

This was the best one of your videos I've watched! You're such a fantastic teacher, thank you so much for making these videos, they really are invaluble.

[@celiasunvoice]

I cannot express how much you have helped me. I am in a 7 week Neuro course and your videos are the only reason I have any idea what is going on!

[@Inuishon]

Zach you are a superb teacher. Learning how to restore the Basil Ganglia back to a healthy state of channeling :) Autoimmune based disoders

[@chococoveredlemons]

This made everything so clear for me!! Your enthusiasm is contagious and you explain everything so well! Thank you thank you thank you!!

[@sabrinamendes8406]

And, once again, your videos are saving me this semester 😭❤️ thank you!

[@kendallhalsey1231]

This explanation is amazing!!!! Thank you from me and my cohort - student physical therapist

[@alaashadad9598]

The passion you explain with such complicated topics is just beautiful! Keep the great videos coming! Thank you

[@kathyswatosh1875]

Thank you so much for your energy, and thoughtful descriptions/diagrams. You are terrific!!

[@AndreaOgSilver]

This is the best video about basal ganglia in the entire universe. Thank you so much!

[@fahrinaulfah1552]

thank you! I've always fascinated by neurology but i found it hard too study it, with your lecture it feels easier to understand

[@NinjaNerdOfficial]

Glad it was helpful!

[@katelynleong9479]

These videos are life savers and delivered in a way that is so much better than the lectures at physio school. Currently studying for my upcoming exams and videos like these are helping me manage my exam stress so much!

[@LightwingsTWENTY2]

My friend is in the ICU for a bleed in this area. I am a Cranio Sacral Therapist practicing remote healing on him. I appreciate the clarity you have offered here! Thank you so much! My gratitude is truly beyond words! 🙏

[@asmitarane8088]

Wishing him a very speedy recovery ❤️🌈

[@DisturbTheTruth]

This is the best video explanation that I have ever come across! Thank you so much❤

[@duhaal-qaderi689]

This is the real mind-tickling neuroscience lectures.

[@martinfaltl2209]

Always found this difficult to comprehend and memorize in class - until I came across this video! Brilliant job of breaking it down, thanks so much!

[@josetrujillo738]

Another beautiful day! Thank god for beautiful humans! Thank god for Ninja Nerds! And thank god for all of our learning, progress, success, love, abundance, and happiness! Another beautiful day! Bless up Ninja Nerds!

[@buthinahammod7858]

Man you are just amazing Keep uploading such great videos I don’t know what would medical students do without your videos🥰

[@nursejax9152]

Came across a basal ganglia bleed case recently and this video helped put things in perspective.

[@ricardolombe8614]

I really cant imagine med school without your lectures. they hit different,. Thank you so much Zach

[@ErikaSchuerle-Uditschka]

Thank you so much for all your Videos! Your explanations are so good. I'm a Speech Language Pathologist working in Neurology and now understand Anatomy, function and lesions much better! Thank you very much!!!

[@mujtabaali992]

you're a legend Zach, truly you're a inspiration for me to do hard work ❤️

[@mdramaqueen121]

I can never thank you enough. We are so grateful of you and your content!

[@lenaingram3055]

wow, I wish my lectures were structured like this. having everything connected visually makes it so easy for me to understand what's being spoken about!!

[@dochala8400]

Want to say that your neurology playlist is absolutely thiiii best 😍

[@jaredheath2184]

my doctorate level neuro professor can't even lay it out this well. thank you so much, sir!

[@saniagambhir4342]

The besttt videos one could ever find on KZbin

[@MsDixielix]

THE BEST medical teaching channel ❤❤❤❤

[@Chielo023]

As a beginner neuropsychologist, I'm truly amazed by your explanatory drawings. You make so many 'simplistic schematics' in my neuroscience books clear and understandable. Thank you for doing this!

[@elizavetanagibina6569]

only gratefully to your creative, detailed and clear explanation i started to understaned neuroanatomy

[@StepsHardcore]

You are a strong light in a room full of darkness. Thank you so much.

[@MrAdmiralKush]

Ok, I have a question though. Near the end, you said that the niagrastratial pathway modulates movement, I get how it enhances the direct pathway, but for the indirect pathway it seems like it increases the motor movement of unwanted motor movements. Isnt this counter productive? why would your body do that.

[@yochinoinazaki3813]

I didn t get that either..

[@lukamiljic8193]

Well, unwanted movement can become wanted movement if it is suddenly needed. So this pathway would be useful for adapting the movement according to your needs. It isn't something that exists to cause spasms, just to ease the transition of a movement going from the indirect to the direct pathway. At least that's how I see it.

[@ash_xclusive]

I think that is because there also exist cholinergic fibres which affect the neurons in the putamen. But the difference is that dopaminergic fibres from the nigrastriatal pathway and cholinergic fibres have antagonistic action, so the net amount of ach and dopamine decides whether the indirect pathway is inhibited or stimulated. So, nigrastriatal pathway does help in modulation of movement. I hope I was of some help😇

[@mukulgidney]

Similar question arose here

[@MrAdmiralKush]

This question is still bothering me, even though I’m well past neuro. I just can’t get over it. Even the doctors as I ask can’t give me a clear answer. Hmmm. Well I’m going to visit my family soon some of which are doctors. So I’ll be showing them this video and maybe they can sit me down and go over it with me. If I can make sense of it I’ll share it here for the rest of you who seem to be in a similar position.

[@jaemeymatherly7598]

Thank you zach. Your board is screenshotted more times than any other youtube channel.

[@ishaparekh6453]

Understood this topic so nicely. Thank you❤

[@kalenced8575]

I cry tears of joy as I watch this video. It's almost midnight, my exams are due in few weeks, and I am finally understanding basal ganglia. Is it too much if I say I love you?

[@dalinalaffita650]

Holy cow, this is the best video on a hard topic I have seen in a long time!!! Write your own book man!

[@keithedward]

Test on Tuesday, perfect timing.

[@trackman07]

Thank you. You prove, when appropriate effort is applied, online learning is very impactful and can be done, improving education on the whole. Cheers

[@moralfantacial4000]

I'm watching your videos from russia, studying psychology. and nevertheless we don't study latin and learn everything in Russian language, your videos make everything so clear. and every time I can't believe they last 40-60 mins, because it feels like 10 minutes. so thank you a lot. you make the best yt content about neurology

[@84sounakmajumdar45]

It really hurts when your video ends ... feel like to watch more and more.... Thank you Zach ❤️❤️❤️

[@annaatrasfitness]

Amazing recap before Neurology exams. Thank you!

[@MegaMahdi11]

I love this man. Him and the ninja nerd team are a gem to us!