Neurology | Enteric Nervous System

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In this video Professor Zach Murphy will be discussing the enteric nervous system. We go into detail on how a food bolus passes through the GI tract, as well as the many components of this system including the myenteric and submucosal plexus. We hope you enjoy this lecture and be sure to support us below!
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#ninjanerd #EntericNervousSystem #Neurology

[@rkeyz686]

He really meant it when he said ninja nerd, splicing these concepts into digestible pieces (pardon the pun). Top notch service sir.

[@vickikelly1106]

Hope you never stop teaching..one.of the best teachers I've come across

[@SkyNikodell]

I am amazed with the amount of detail you manage go into in a short video like this, when professors can't even explain this in a two hour lecture. Thank you once again for all your videos!

[@gingerscally1678]

I was thinking the very same thing!!!!

[@PhucNguyen-iz9nc]

I also think so

[@boredpotato2176]

Thank you so much for your videos I can’t be more grateful, complex Medicine Concepts couldn’t be simpler and clear than this

[@assia4099]

i really injoyed this video very helpful

[@user-mr4dh8gt2d]

thank you sir for your teaching

[@mihretaman9860]

Thanks, it is very helpful to understand GIT

[@sajiruddinsk8129]

Thank you so much, Jarur, Murshidabad WB India.

[@iremarslanyurek-gaziuniver9930]

Thank you🤍♥️♥️🥂🥂🥂

[@sarbajitchowdhury6796]

Great job!!

[@tariqjagmag]

eating a pizza and watching the video...makes understanding easy.:)

[@blacksonphiri3034]

Amazing

[@noobrider0163]

In the chepalic and gastric phase video, you said S.N.S comming from T1 to L2, but in this video you said from T5 to L2/3. Which one is corect?

[@senadonkor2228]

T5 to L2

[@adwaithsarma7322]

T5 to L2 - reference : guyton

[@zamirkhan6429]

From t1 to t5 sympathetic chain supplies to thorax.from t5 to l2 it supplies to abdominal and pelvic viscera (all types of splanchnic nerves).

[@noobrider0163]

@@zamirkhan6429 aahh, I see. Understood sir. Thank you so much for the answear.

[@KarenLeggett]

3 words... I love you! okay... 2 more words... YOU ROCK. okay... 2 more words. THANK YOU. I've been practicing medicine for 20 years and this was the best anatomy and physiology review I could have ever imagined finding. I hope today's medical students (and others) know how lucky they are to have the internet and people like you so gifted in teaching!

[@NinjaNerdOfficial]

Thank you so much Dr. Leggett 😄

[@destinyesebameno.872]

true and well spoken

[@onurturhal6814]

We know🌈

[@himanshuambilkar4160]

Food distension Stretch receptor Ascending fibers Descending fibers. Ascending fibers- Oral side Stimulate inner circular muscle constrict SubstanceP Ach. Inhibt outer longitudinal MUSCLE Vasoactive intestinal peptide,nitric oxide.... Stretch receptor Anal side Descending fibers Circular inhibt Longitudinal stimulate.... Chemoreceptors- FA,glucose Chemoreceptors Submucosal plexus Sub mucosal gland Dilate blood vessels. H+,FFA Chemoreceptors S cells hetro endocrine cell Liver bile Pancreas p.juice. Hco3- I cells Cck Gall bladder Pancreas Sphincter of oddi... Glucose- Chemoreceptors Submucosal plexus K cell Glucoinsulinotropic peptide GIP. Extrinsic system- Sympathetic nervous system Inhibt T5-L3 Decrease Motility Secretions Absorption Blood flow. Prevertebral ganglion Celiac Superior mesenteric Inferior mesenteric Constrictor - Pyloric Internal anal sphincter... Parasympathetic- Dorsal nucleus of vagus Post ganglion cell bodies Sub mucosal Myenteric plexus. Increase Motility Secretions Relax sphincter... Short reflex. Long reflex- Vago vagal reflex Chemoreceptors Gva of vagus nerve Dorsal nucleus of vagus Gve of vagus.... Enterogastric reflex- H+More Stretch receptor Prevertebral ganglion Thank you sir

[@drakpriyadharshini963]

You made it very easy🤗🤗

[@weownwellbeing2709]

thank you, cool summary

[@luziqa4046]

my first source in understanding physiology

[@jefferybeck256]

You just cleared up so much confusion over a few days worth of lecture in less than 40 minutes. Truly a hero to medical students. 🙌

[@xtasyyu682]

digestive system physiology in its simplest form. well done.

[@NinjaNerdOfficial]

Thank you very much!

[@finlan212]

@@NinjaNerdOfficial hello Ninja , please , incase am asked to discuss regulation of the GIT functions .can I use the above approach ?

[@dianaz5937]

I love your videos! I'm a physiology graduate student and you are my salvation! I'm extremely impressed, as others have said, with the level of detail you go into while staying concise and keeping your viewers engaged. Your energy for science gives me life. Happy to be a ninja nerd!

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Your energy for science gives me life. Happy to be a ninja nerd!

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You gotta be kidding me; “it’s getting hot in here guys, I’m getting excited for science”; that was ridiculous perfect, and funny; just to perfect. Ahahahahah! TO DANG FUNNY! And to dang perfect!!! Ahahahahahaahahah!

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The doodoo hole side 😂

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Dude, you are soo good. I really understood it and I can pass my exam now thanks to you. I'm crying tears of joy rn cause I understand.

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[@eliasjosemanuel4436]

Oh yeah

[@akifhadri]

I'm a year 2 pharmacy student, and your videos really help me to get the overview and also get to see the bigger picture of the discussed topic. I'm really amazed with the way you explain the details of the mechanism, reaction and etc. Don't stop making videos, cause it really help students :)

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15:09 dies in cuteness*

[@muhammadikhsan4747]

i am trully grateful that i've found your channel because of it i learn easier than what i get from my lecture , god bless you man !!

[@lachlansutherland5752]

what a brilliant video!! been reading my text book with just confusion - now it all makes sense!! thanks so much :)

[@Rayan.Arysun]

Awesome! Would you please leave the donation link here as well

[@NinjaNerdOfficial]

Thanks for watching, hope it all helped! The donation link can always be found in every info box of our videos. www.Patreon.com/NinjaNerdScience Thank you for your support!!

[@dombarton2483]

Absolutely fantastic! How can anyone ever leave a thumbs down!!! Are you planning to do more pharmacology videos as they seem rather empty..really enjoyed your series on antibiotics.

[@IPlayAces]

Brilliant. Best "simple" explanation of a very complex ENS I've heard/read/seen so far. I'll be recommending this video to anyone who has interest GI physiology, nutrition, gut-brain connection, etc.

[@shuzhenchee8409]

Thank you for this video, it made me understand the slides in my lecture. Your passion in teaching also made a difference. Keep doing what you do!

[@hannyween]

Been reading articles on this for 2 days. Watched this and got it in 30 mins. THANK YOUUUUU!!!

[@sarahelhalabi8059]

best overview of the enteric system that I've come across in the past few years. So well done!

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You are amazing at this rate I will pay you my school fees

[@talalalhejaili3768]

After all years passed in practicing medicine, finally got the best here to explain the basic medicine sciences, really awesome

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I dont know what to tell you u made my life easy thank u and i love u

[@sachinbharti5953]

Sir, Respect towards your hardwork and detailed explanation within short lecture..Love your funny way of teaching whenever you say "what this Sucker can do?"🤣 But for us 1st yr students it seems lot of difficult to understand detailing..We are used to mug up books few details of physiology...Salute to your easy explanation...👏👏🙌

[@zeljanaradonjic9942]

These are amazing videos. Thank u so much for the energy and all the time it takes to make a lecture. I was just wondering If someone could explain whether the strech receptors are found in submucosal layer or the external muscular. One video says one thing the other another

[@o0LadyCosplay0o]

Thank you. I never really got to visualise this well enough to understand the whole picture until now.❤️ Love and support 💕

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I do not have words to express myself on how impressed I am with the quality of work you guys deliver on these amazing FREEEEE videos. Thank you very much!!!!

[@kumarashutosh6795]

The coolness in your teaching and your style, is what makes me study physiology in a efficient manner. Thanks a lot from the core of my heart to inculcate the interest towards the subject,I used to hate.

[@nadagamal4458]

Thank you for these super helpful videos, but There is one little comment, the inner circular layer actually appear as longitudinal structures under the microscope and longitudinal layer appear as circles because it is a cut section.

[@shahbaz9231]

quality material with that accent makes it easy to understand. Thank You Sir,You've got a new subscriber.

[@palesamtshali963]

Thank you for this amazing explanation.

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This man is getting me through med school 😭😭😭

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Simply awesome. Excellent explanation, love your attitude.

[@brookellsalewske8628]

This is the only place I found such a clear cut explanation! Thank you!!!

[@simsonsoren1259]

Thanks a lot for the videos. it helps me to teach my UG student instead of going through many books. Keep it up, sir. All the best.

[@asrizawani4467]

It's a very clear explanation ! Without this video I think I cannot understand better. Thank you for helping students science health like me :)

[@alih6953]

I am able to easily digest the digestive system because of your awesome lectures!

[@painfullyhonest]

thank you for taking the time to put these videos together. I am concerned about a move to connect the "gut brain" to consciousness or intuition. Have there ever been any replicated clinical studies to show that the neuronal/glial network from the gut impact conscious awareness similar to the neronal/glial network in the head brain?

[@yvonnevillalba7722]

Amazing video! Thank you for the concise explanation of such a complex system. Your videos are truly the best.

[@johna2567]

Very interesting video.... Thanks for making these videos... Could you make videos on - pathologies of GIT

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For me I'll use sentence and not word to describe him .....STUDYING MEDICINE MADE EASY🤣🤣🤣🤣🤣. Bravo ,hoping to see you one of these days being welcomed into my country to give lectures or inaugural lecture👍👍👍

[@60-sheetalmishra6]

Oo my God..😀I'm so grateful that I found this..I'm just speechless ........ thanks a lotttttt☺️☺️☺️🤩

[@raksharavikumar6885]

Amazing explanation, but you should’ve kept broccoli instead of pizza. I’m hungry :(

[@elsiezinl6365]

Such a wholesome GIT physiology video Amazing job man you really are doing the most

[@srinivasan7892]

You didn't say about intestinal cells of cajal(ICC)?? They are the one that creates action potential and contractionisn't it?? But you are saying that myenteric plexus is the one that is creating contraction.. then what about ICC? Please clear my doubt...

[@jtomwalker6233]

This guy kinda reminds me of Turk from scrubs. The facial expressions and physique is spot on, i cant help but picture JD behind the camera filming

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Chemimolicular electronic synopsis physic transmission. This theory, i developed with an old retired UK professor in the past. The speed? Light speed.

[@nisargshukla6626]

I now understand enteric nervous system. You made this so easy and simple, like it all went into my head. Thank you.

[@robyncuthbert2062]

Amazing Video!!!! Mind is blown :D Is there a similar video but discussing the nerve innovation of the pancreas, going into detail on the enteropancreatic reflexes and the pancreatic plexus ? Discussing acinar and duct cells

[@NinjaNerdOfficial]

Check out the Discord! You can have discussions with nearly 13k others of the Ninja Nerd community! - TG

[@jayyoo906]

My son will invent AI product by my theory and brain hyperthalamos cognition functions.

[@justiceleague9619]

You think it could be possible (with technology probably) to disable medicines from working as should do?

[@carlstuvek9340]

Thank you so much for the video! Maybe I’m misunderstanding, but I think at 10:25 you say when the longitudinal muscles contract that they open up the lumen in front of the bolus , but at 12:00 you say that when they contract it opens up the lumen behind the bolus? Otherwise super helpful, your lectures help get me through school!

[@zahraahussein5749]

No He said that longitudinal muscle must be inhibited cuz we don’t want them to contract to squeeze the bolus into the oropharanges If they contract they will close the lumen in front of the bolus , we wanna stimulate the circular muscle to contract and inhibit the longitudinal in order to open the lumen in front of the bolus to makes it moves towards the stomach

[@vemulakondachaitanya9700]

at 10:45 you said that when longitudinal muscle relaxes the lumen behind it increases in size. My Doubt : if lumen behind the bolus increases in size then how does bolus pushed forward. My opinion : lumen behind bolus needs to be decrease in size to push forward right.

[@valeriaflores6452]

I've learned more watching this video than in my online classes xd well done!!

[@muhammadhilmanalmadani9192]

thanks a lot professor zack, and also the crew!, bless u all, and i hope granted of health, wealth, i can't wait when i become a doctor so i can support u more!

[@q.w.5306]

Awesome explanation! I love your videos👍👍👍👍👍👍👍👍👍👍👍👍👍

[@itsi4778]

Thank you very much! You are a life savior in a most needed time 🤩 we just recieved our lecture notes but had to learn this on our own 😫

[@yusufbackshi9459]

Great educational videos. Can you repeat the full name of a structure or substance or function after you have mentioned it instead of referring to it as this guy or this thing, wish you more success. Thanks

[@aamirejaz7872]

Thanks Bro for making Med science easy for us... I always prefer u.. ❤️❤️

[@roblems8]

So, when the GVA is activated by stretch receptors, does this mean it decreases your hunger, because it signals satiation?

[@0scarchibwe4496]

All the lecturers say that certain people don't really include the enteric nervous system as part of the NS,,,, then who really is it that doesn't include it?

[@sudhanjanan1728]

How to make contribution to you guys.....I am in India.....how can I pay?I mean through what way

[@BenadiBawanya]

We love your crystal clear teaching ❤🎉😊keep it up sir!👏👏👏

[@tibayounis9977]

Sorry can any one answer me why when the longitudinal muscles contract it increase the lumen the lumen thickness will increase during contraction of longitudinal how does its(lumen) increase 😟

[@achintakrdas8354]

Hatsoff sir .......once again m pleased to see this..so easy nd simple

[@sandradelic6132]

My best regards from Serbia...and thank you a lot for your help

[@dailypill5783]

i think that in T.S longitudinal and circular smooth muscles should be drawn other way round

[@noumanakram6630]

Thanks sir you are the best teacher.i love your videos .you are just amazing

[@walterfaber7784]

Fight or Flight -> sympathetic Rest and Digest -> parasympathetic

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Me: How many times do I have to say it's so cool ? Students : Yes !

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You are amazing and magic you can't emagine how much you help me thanks from algeria

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i always say there is no way this is gonna tell me all I need to know, then you go ahead and explain it all like a symphony

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it is really cool, i really love it. Thank you so much :3 From VietNam

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🙏🏻🙏🥹❤️🩷💗💜💜💓💕

[@marinajoannides7095]

We have dysphagia and access mucus. Where is the problem?

[@اميراحمدعبدالكاظمحسن]

I have confused between cajal cells and enteric nervous system 💔😅

[@buraaq7]

Sir i think this is the longitudinal section of duodenum not transverse section !!!!!!

[@hoseinjalalvand2055]

Ninja your next series of teaching should be histology there is no a good channel on you tube for histo and histo is so important

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estoy absolutamente ENAMORADA de TODOS TUS VIDEOS!!!! you are a geniuuuss!!!!! best profesor ever, en serio!!

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i am very thankful to you ...i gonna buy a lot of ninja nerd t shirts from amazon and wear it for my life time

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Thanks a million my man; you are simply a bomb! Your presentations are excellent and extremely helpful.

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Thank you! You’re saving my life

[@jamie6311]

Just wanted to say thank you soooo soooo sooo much- your videos are always so comprehensive and helpful. The drawing and explaining in real time helps me understand so much better than pre-printed powerpoint slides.

[@abhisheksah2772]

#From_Nepal.This is really really good lecture sir...TQSM ...

[@zummararahim6797]

the only person whose lectures i understand N love to listen ❤ thankyou sir

[@tanishkgovil4809]

Thank you brother for this great knowledge ina short video

[@baswarajmunge3120]

I think ..this is the best video on enteric nervous system..thank you sir@ india