Extracting the spicy chemical in black pepper

  Рет қаралды 2,178,047

NileRed

NileRed

Күн бұрын

Пікірлер: 2 600
@bryandelahoz6063
@bryandelahoz6063 5 жыл бұрын
"...I'll use a different spoon, just to keep my piperine clean..." *proceeds to spill the entire yield all over the table*
@Your_Sweater_
@Your_Sweater_ 5 жыл бұрын
I was just about to make this comment.
@falvius9804
@falvius9804 5 жыл бұрын
When I saw that I just went "now SNORT it"
@charleschidsey6192
@charleschidsey6192 5 жыл бұрын
I thought he was gonna do a line.
@urishima
@urishima 4 жыл бұрын
@@falvius9804 That'll get you going in the morning
@hyvll
@hyvll 4 жыл бұрын
@@falvius9804 "Hi, my name is "NileRed"... and welcome to Jackass!"
@thisismyotheraccount1863
@thisismyotheraccount1863 5 жыл бұрын
Extracting the ‘spicy’ chemical from spicy peppers. The conclusion he comes to is ‘it’s spicy’ I love science.
@Gmod2012lo1
@Gmod2012lo1 5 жыл бұрын
@@bufferr_ you made my day :'D lmfao
@jaytheviking2706
@jaytheviking2706 5 жыл бұрын
Black pepper dood. Spicy peppers like jalapeños or ghost peppers contain capsaicin
@Alontrle
@Alontrle 5 жыл бұрын
no he said "it's spicy, but not that spicy"
@omnacky
@omnacky 5 жыл бұрын
@@Alontrle you're not that spicy
@Alontrle
@Alontrle 5 жыл бұрын
@@omnacky you wanna go I'm like the ghost pepper of this shit..kidding im a green bell pepper at best
@credocooperative
@credocooperative 7 жыл бұрын
extract menthol from mint leaves
@great__success
@great__success 7 жыл бұрын
yes! I got vial with menthol crystal and they are amazing !
@raccoon344
@raccoon344 7 жыл бұрын
Ben Dover you eat those
@hughmcrae3510
@hughmcrae3510 7 жыл бұрын
You could probably get lots of it from menthol soothers. I'd say a heck of a lot more.
@AssistantLeaflet
@AssistantLeaflet 7 жыл бұрын
extract acetyl-Aldehyde from peppermint.
@matttorres5510
@matttorres5510 5 жыл бұрын
@Willem DaFuckedUp Willem DaFoe you are supposed to be retired.
@dizza8742
@dizza8742 3 жыл бұрын
Nile: "The piperine was super fine" *piperine blushes*
@pumkin610
@pumkin610 3 жыл бұрын
UwU
@nukkonyan
@nukkonyan 3 жыл бұрын
@@pumkin610 OwO
@aminahajayi
@aminahajayi 3 жыл бұрын
The Piperine: Why Thank you, UwU.
@Akon1998hell
@Akon1998hell 2 жыл бұрын
Noooooooo
@meghanaweee8351
@meghanaweee8351 2 жыл бұрын
OwO UwU EwE RwR
@uilsoum875
@uilsoum875 5 жыл бұрын
NileRed: im lazy Also NileRed: *spends months on singular project*
@ckv954
@ckv954 5 жыл бұрын
uilsoum he’s smart person lazy. So smart that they know how to put in the least amount of effort
@Lucy666Fernandez
@Lucy666Fernandez 4 жыл бұрын
That's why he spends months on it probably. If he wasn't being lazy he could finish most projects within a few days to weeks (excluding the time he actually has to wait for some stuff).
@MajinObama
@MajinObama 3 жыл бұрын
@CKV „Is it possible to learn this power?“
@at1one
@at1one 6 жыл бұрын
Extract baby oil from babies
@gabrielmotoc1234
@gabrielmotoc1234 5 жыл бұрын
haha, that's a good one
@unclekanethetiberiummain1994
@unclekanethetiberiummain1994 5 жыл бұрын
If you dried it you could make baby powder.
@right9128
@right9128 5 жыл бұрын
@@unclekanethetiberiummain1994 dehydrated baby
@joehendo
@joehendo 5 жыл бұрын
@@unclekanethetiberiummain1994 if you cooked it you could have baby food
@gavindillon1486
@gavindillon1486 5 жыл бұрын
@@right9128 dry baby dessicate neonate
@jonathoncliffbailey
@jonathoncliffbailey 7 жыл бұрын
Dear NileRed, pure capsaicin isn't very spicy because it requires a carrier oil to stick to the mucous membranes and cause irritation (aka the burning sensation). Could it be that Piperine requires a carrier oil as well? Couldn't find anything online to confirm this.
@Omaroka
@Omaroka 6 жыл бұрын
MrFibonacci You're smart.
@Lambda_Ovine
@Lambda_Ovine 5 жыл бұрын
@@Omaroka He is.
@jeffmoore4657
@jeffmoore4657 5 жыл бұрын
Try olive oil (xv) or black walnut oil. These seem good as they cut white(yellow) phosphorus for demos.
@rachelmoody1520
@rachelmoody1520 5 жыл бұрын
Probably not, as he could still taste the spiciness. What he meant by "nothing" was probably that it was ONLY the spiciness, usually in food spiciness is just one flavor amongst many, so the burning sensation has background flavors that are actually tasteable, and not just sensations.
@CyberFae777
@CyberFae777 5 жыл бұрын
@@rachelmoody1520 no the point is that its not as spicy as its supposed to be
@gayrainbowunicorn1367
@gayrainbowunicorn1367 7 жыл бұрын
Nile you have made such progress.... And even when you had a low number of subscribers, you never lost the quality of the videos... Keep up good job
@ravenous9577
@ravenous9577 7 жыл бұрын
GayRainbow Unicorn xx i wonder if he will do a face reveal for us when he hits 150k 😍
@aliendiscrimination2541
@aliendiscrimination2541 7 жыл бұрын
he also did a face reveal in the green chemistry video
@GBL337
@GBL337 7 жыл бұрын
And he is actually cute as hell...>_>
@aliendiscrimination2541
@aliendiscrimination2541 7 жыл бұрын
he is..
@TurTortle
@TurTortle 7 жыл бұрын
What? He's at the end. And has been in a lot of his recent videos.
@wholegrainyeetthins9386
@wholegrainyeetthins9386 5 жыл бұрын
you made pepper for people who consider salt spicy
@percizioncyborg5617
@percizioncyborg5617 4 жыл бұрын
Lmfao
@miguelangelhernandezsolis7849
@miguelangelhernandezsolis7849 4 жыл бұрын
@Vanargand I am Mexican that sounds worse than death for me
@miguelangelhernandezsolis7849
@miguelangelhernandezsolis7849 4 жыл бұрын
@Vanargand that was a joke genius
@WaterWizard1000
@WaterWizard1000 4 жыл бұрын
It's ok girls, you can both wear a blue dress to the prom..
@PsicosisYT
@PsicosisYT 4 жыл бұрын
@Vanargand Sennssiiiitttiiiivvveeee
@shadowtheimpure
@shadowtheimpure 4 жыл бұрын
The soxhlet extractor is one of my favorite pieces of glassware. It's extremely useful, even in the culinary world. I use it with ethanol (ever-clear) and ground dried ghost peppers to extract capsaicin to enhance hot sauces.
@ryanrosser7916
@ryanrosser7916 3 жыл бұрын
“Enhance” what kind of sadist are you?!
@ruinenlust_
@ruinenlust_ 3 жыл бұрын
Scrolling through the comments and so I learned that apparently it's not called a "socks hood" extractor smh
@cminchy
@cminchy 2 жыл бұрын
Also, “soxhlet extractor” is so fun to say
@cybeermancom1
@cybeermancom1 7 жыл бұрын
takes a new spoon to keep his product clean dumps it on the table a few seconds later xD
@NileRed
@NileRed 7 жыл бұрын
Not the most efficient.
@NicolasBana
@NicolasBana 7 жыл бұрын
13:27 "I actually took about the same amount. So i have..." dumped everything on the table yes ! Your face was priceless !
@OsirusHandle
@OsirusHandle 7 жыл бұрын
Wiki says so far circumin has not shown to do anything good for you and is overall useless, but it false-positives a lot of health tests.
@albertjurkowski9038
@albertjurkowski9038 7 жыл бұрын
Nicolas Bana YES!!!!! 😂
@Lierofox
@Lierofox 7 жыл бұрын
NileRed How much time elapsed between the "...oh." moment and the moment you were able to resume the video? Also how long until we see the cut footage?
@sadsushiroll6395
@sadsushiroll6395 5 жыл бұрын
Nile - *Uses spoon to keep it pure* Product - *spills all over table* Nile - :0
@Mrmich5371
@Mrmich5371 4 жыл бұрын
Z🤣 poor guy
@micahmwah
@micahmwah 2 жыл бұрын
loll
@Felixkeeg
@Felixkeeg 7 жыл бұрын
I'm four semesters into my chemistry bachelor and we just started with the organic lab last Monday and boy - my appreciation for your videos has easily quadrupled since then. Organic Chemistry is so tedious and takes so long and you go through all the hard work just to present us the cool stuff condensed into 10-20 minutes. Recommending you to all my pals from university now, so they can see some lab techniques btw ^^
@hottiekitty96
@hottiekitty96 4 жыл бұрын
Same boat hello!
@zrspangle
@zrspangle 3 жыл бұрын
What're you doing with your degree nowadays?
@blank888
@blank888 2 жыл бұрын
@@zrspangle He has become Heisenberg, Making coainer
@freezy2755
@freezy2755 2 жыл бұрын
Chemistry degrees are useless unless you get a masters
@John-B-Goodenough
@John-B-Goodenough Жыл бұрын
@@blank888 what I’m tryna do. You’d be amazed how easy it is for some stuff. Nothing good is easy but there’s some hallucinogens that take 6 hours and 3 separate easy to find chemicals to extract. Life is sometimes awesome
@Cosmioful
@Cosmioful 5 жыл бұрын
When doing a soxlhet extraction, I would always put my material in a reagent tube made from fine mesh cotton, and plug it with cotton - this would enable you to powder the pepper corn as fine as you wish, increasing the yield
@brylozketrzyn
@brylozketrzyn Жыл бұрын
Or use paper filter tube. These are also food grade and are just hassle free to use
@crayoneater68.5
@crayoneater68.5 4 жыл бұрын
7:39 - Me when I do the dishes
@mikatheviking6137
@mikatheviking6137 4 жыл бұрын
so good but so few likes... same tho
@guzzino97
@guzzino97 4 жыл бұрын
nice.
@jakep111
@jakep111 4 жыл бұрын
When im wiping my ass
@gobodk9652
@gobodk9652 4 жыл бұрын
@@jakep111 ahahahah. you got me "waking up my parents in the middle of the night" laughing
@miranda.cooper
@miranda.cooper 4 жыл бұрын
When my dog is done licking my plate
@seanjohnson4141
@seanjohnson4141 7 жыл бұрын
YOU PUT THAT in the fridge? "oh orange juice" *shlurp* "Ahh my liver!"
@Karreth
@Karreth 4 жыл бұрын
He almost certainly has a separate lab fridge.
@calebangell77
@calebangell77 4 жыл бұрын
@@Karreth and who drinks orange juice from a beaker with plastic wrap over it?
@joofjoof2280
@joofjoof2280 4 жыл бұрын
Caleb Angell how do you store your orange juice? That seems perfectly normal
@TheTdw2000
@TheTdw2000 4 жыл бұрын
@@calebangell77 do... do you not?
@red2theelectricboogaloo961
@red2theelectricboogaloo961 4 жыл бұрын
liver hurting juice
@holdinmcgroin8639
@holdinmcgroin8639 7 жыл бұрын
It makes sense that it doesn't taste like anything. The piperine only interacts with heat-sensitive membrane proteins and not other proteins related to taste. So it's basically just concentrated "heat"
@NileRed
@NileRed 7 жыл бұрын
apparently the fact that it doesnt dissolve well either takes a lot of taste away.
@matman7546
@matman7546 7 жыл бұрын
NileRed is it possible to make a water soluble salt of piperine
@aposvlah1855
@aposvlah1855 7 жыл бұрын
Holdin McGroin i did not understand ... where did you learn about interactions of piperine? biochemistry??
@holdinmcgroin8639
@holdinmcgroin8639 7 жыл бұрын
yes
@aposvlah1855
@aposvlah1855 7 жыл бұрын
Holdin McGroin can u explain me what he said at 2:10
@albertoterk9668
@albertoterk9668 7 жыл бұрын
Fun-fact: Cosmetics industries uses capsaicin along side with epiderfill on lipsticks in order to cause a minor irritation that make the lips grow in size by just a little bit. Also, as a chemist undergraduate, i love your videos and i forbid you to stop making them.
@aposvlah1855
@aposvlah1855 7 жыл бұрын
Alberto Terk i am in second year can you explain me what had he done?
@albertoterk9668
@albertoterk9668 7 жыл бұрын
As the hot solvent recondense on top of the crushed pepper it pass through it and carries the piperine with it Hes just using some fancy pants glassware(Soxhlet extractor) to keep things simple and easy. You can alternatively extract by drag if i'am not mistaken, but as he stated is much more 'labor intensive'.
@Weaseldog2001
@Weaseldog2001 7 жыл бұрын
That's pretty much it. The Soxhlet extractor, keeps recycling the same alcohol, so that he ends up with a more concentrated solution at the end, than if he just heated the pepper in a large quantity of alcohol and boiled it off. The extract works as a d distillation unit, so the the evaporated alcohol is mostly pure when it condenses at the top. It's hot and as it drains through the pepper, it dissolves the piperine. When the siphon tube fills to the top, it quickly drains the solution with the dissolved piperine, and the cycle repeats. The siphon tube is working with the same principle as a flush toilet.
@lebakas_peppi
@lebakas_peppi Жыл бұрын
How are you doing now, 5 years later?
@marooon9814
@marooon9814 5 жыл бұрын
Oh my god your expression when you dropped it was priceless, so sweet
@wetowl479
@wetowl479 4 жыл бұрын
What are thirsty girls doing here? This is a science video
@swordsmancs
@swordsmancs 4 жыл бұрын
Lil Borki girls can thirst for cute science boys and science, there’s no limit on the thirst that is possible
@TheDeadOfNight37
@TheDeadOfNight37 4 жыл бұрын
@@wetowl479 how dare someone express a feeling
@thesovietkevin7275
@thesovietkevin7275 4 жыл бұрын
thirsty? drink the chemicals
@belvederebaileycambodia
@belvederebaileycambodia 4 жыл бұрын
he doesn't have facial expressions.........ever
@TechFish3K
@TechFish3K 5 жыл бұрын
Drinking game: take a shot every time he says “isopropanol”
@ChiffCharang
@ChiffCharang 5 жыл бұрын
*take a shot of isopropanol every time he says "isopropanol"
@MediaSubliminal
@MediaSubliminal 5 жыл бұрын
We'd all die from alcohol poisoning before the end of the video
@gregorykhvatsky7668
@gregorykhvatsky7668 4 жыл бұрын
@@ChiffCharang take a shot of whatever alcohol he names when he names it. You might even live
@brandonveltri2825
@brandonveltri2825 4 жыл бұрын
Gregory Khvatsky methanol it is👍
@swordsmancs
@swordsmancs 4 жыл бұрын
I tried counting every time he said “isopropanol” in the video (not counting alcohol) and it looks like you’ll be drinking 12-13 shots for the game
@al_kaloid
@al_kaloid 7 жыл бұрын
Have you considered dissolving the piperine in some sort of cooking oil and tasting it afterwards? I guess due to the poor solubility there's no chance for the piperine to unleash its full potential on your receptors.. Edit: Btw - great format! :)
@chloelavoie5568
@chloelavoie5568 4 жыл бұрын
Nigel: I’m lazy Also Nigel: *does everything else he does on his two channels and is one of the most productive KZbin creators I know*
@kajamatousek247
@kajamatousek247 Жыл бұрын
Nile 5 years ago : Let's extract spicy chemicals from food Nile now : Building a nuclear reactor from scratch in his garage
@wontonschannel
@wontonschannel Жыл бұрын
in 1 minute
@y66502
@y66502 Жыл бұрын
now he creates the spicy chemicals
@crazilycrazy29
@crazilycrazy29 Жыл бұрын
He really went from "This is my science project, hope you enjoy" to "Is it possible to eat gloves?"
@RandomMan-nv2qh
@RandomMan-nv2qh 5 жыл бұрын
Never eat or drink in lab Nilered HOLD MY FLASK
@Merennulli
@Merennulli 4 жыл бұрын
He went to the kitchen to eat it.
@nimmen
@nimmen 4 жыл бұрын
high school chemistry: having a bag of sweets next to your titration setup because it just takes forever
@word6344
@word6344 3 жыл бұрын
Hold my toilet paper moonshine
@Tower0fHeaven
@Tower0fHeaven 7 жыл бұрын
You have set a dangerous precedent by tasting your product in this series; The viewers will demand more sacrifice. Good Luck
@calvintimorous4904
@calvintimorous4904 7 жыл бұрын
Already excited for this series
@asclepius3071
@asclepius3071 5 жыл бұрын
I'm actually learning from all this, this made me want to take some classes and i'm also doing research too on all of this. Thank you i've never been this happy in a while, you're such an amazing inspiration.
@thefirstsalty3055
@thefirstsalty3055 4 жыл бұрын
*eats all the piperine* "what does it taste like" "P A I N"
@arthurneddysmith
@arthurneddysmith 4 жыл бұрын
0:44 Chavicine, AKA: "essence of English bogan".
@kais2345
@kais2345 7 жыл бұрын
Very jealous of all the glassware/equipment you have access to!
@Weaseldog2001
@Weaseldog2001 7 жыл бұрын
It's all available online.... www.coleparmer.com/i/kimax-601000-0624-soxhlet-round-bottom-flask-500-ml-1-pk/9903766?PubID=UX&persist=true&ip=no&gclid=CjwKCAjwhOvPBRBxEiwAx2nhLisZDN8itw3PVInSDfXM79mdCy-WjCZCr_okYx7_CvRYMHrP7HCb1BoCf70QAvD_BwE
@drippingwax
@drippingwax 5 жыл бұрын
Very jealous of how intelligent this fifteen year old is.
@zerotwo8251
@zerotwo8251 5 жыл бұрын
@@drippingwax he is 28 this year
@genericalfishtycoon3853
@genericalfishtycoon3853 5 жыл бұрын
@@Weaseldog2001 Whoa! You can buy things on the internet? WOW! I never knew! Without a doubt, he's referring to the price. Smug, or ignorant. Either way, your comment sucked. Just thought I'd let you know.
@Weaseldog2001
@Weaseldog2001 5 жыл бұрын
@@genericalfishtycoon3853 I'm glad I could help you. Yes, posting links to where you can buy things, does suck. I can see how you'd hate people who post links.
@disc_priest
@disc_priest 7 жыл бұрын
Yay! Someone is finally doing edible chemistry
@spookywizard4980
@spookywizard4980 7 жыл бұрын
Acrimonious Oxide all chemistry is edible ;) you just might not want to eat it
@kevincrossland1898
@kevincrossland1898 7 жыл бұрын
Acrimonious Oxide what codys lab has been eating indium and whatnot for years???
@disc_priest
@disc_priest 7 жыл бұрын
Kevin Crossland Oh yeah I forgot. I remember he drank cyanide, mixed KOH into drinks,...
@screengames5307
@screengames5307 7 жыл бұрын
+Kevin Crossland He hasn't been "eating" indium, he only chewed it like chewing gum. Even if he did it's non toxic so meh.
@michaelrose93
@michaelrose93 7 жыл бұрын
That's MDA, Ecstasy is MDMA
@ohmyg0shh
@ohmyg0shh 7 жыл бұрын
You are literally so adorable please show your face more
@jhyland87
@jhyland87 5 жыл бұрын
Hes a part time model, on the side.
@derpinbird1180
@derpinbird1180 5 жыл бұрын
@@lt-devilwolf3871 Incel.
@graysonmusic.
@graysonmusic. 5 жыл бұрын
@@derpinbird1180 LMAOOOO
@Girthopkins
@Girthopkins 5 жыл бұрын
Cryptic Wolf3391 Jesus, shut up she’s just complimenting someone.
@klazzera
@klazzera 5 жыл бұрын
@@Girthopkins omg what happened here
@julidiamondlover
@julidiamondlover 4 жыл бұрын
Extract the depression from my brain!
@mikehunt4048
@mikehunt4048 4 жыл бұрын
Sorry there's not enough brain to work with. The depression yield would be too low.
@julidiamondlover
@julidiamondlover 4 жыл бұрын
@@mikehunt4048 too low for what? Good try, but not a very well thought out quip.
@calvinmoe8465
@calvinmoe8465 4 жыл бұрын
Dat funny haha you sad and said joke!
@NoodlePastie
@NoodlePastie 4 жыл бұрын
Kratom and dxm are nice but addiction can lead to dependence which is absolutely horrible.
@cobaltnitrate8942
@cobaltnitrate8942 3 жыл бұрын
@@NoodlePastie what
@NHL17
@NHL17 3 жыл бұрын
Love this! Current food science student and chef, and we haven't done anything like this in the lab...yet. Keep it up man, this kind of inspiration keeps me going through midterms and long reports - reminds me why I chose this field.
@matthewcromar9944
@matthewcromar9944 2 жыл бұрын
Thank you for keeping 13:26 in, you point at it briefly with an "oh shit" look and gesture and then you move on like a pro. 🤣 I love your channel!
@sethr.c1065
@sethr.c1065 2 жыл бұрын
9:30 Don’t confuse the fresh orange juice with the pepper extract, potasium hydroxide, isopropanol and water
@shupp6267
@shupp6267 5 жыл бұрын
"Tastes like nothing." - NileRed "Tastes like emptiness"- HTME
@gud_soup6991
@gud_soup6991 3 жыл бұрын
His videos are both relaxing and educational, his consistency with the editing is so satisfying. Easily one of my favourite KZbin channels.
@nc5809
@nc5809 17 күн бұрын
This is excellent content for those of us interested in health AND entertainment. Many are interested in Piperine as a medicine and health channels rarely go into this kind of depth. This is very good.
@fpm1979
@fpm1979 7 жыл бұрын
I wonder how coffee would taste if brewed with a Soxleth-extractor.
@TheFinalMB
@TheFinalMB 3 жыл бұрын
Full immersion + filtration. I would guess it’d taste like what you’d get from using a clever dripper. This gives me an idea for a video *runs to cupboard and has neither a clever or a Soxhlet extractor*.... never mind
@dananskidolf
@dananskidolf 3 жыл бұрын
That was my thought too. But reboiling your coffee over and over will make it terrible... perhaps not if you do it at low pressure so it boils cooler.
@lrmackmcbride7498
@lrmackmcbride7498 3 жыл бұрын
That is called a perc pot. Brewing coffee with a perc pot is an art. You have to stop it at the right point or it gets bitter.
@blug407
@blug407 7 жыл бұрын
Sounds like a great idea for a series!
@MattJohnVO
@MattJohnVO 7 жыл бұрын
FINALLY, SOMETHING I CAN EAT WITHOUT GETTING POISONED IN 9000 DIFFERENT WAYS! I would love to see more of these Edible Chem videos in the future man, I really enjoyed it!
@NileRed
@NileRed 7 жыл бұрын
Thanks, more to come for sure!
@xWood4000
@xWood4000 7 жыл бұрын
Cheeser100 The isopropanol is a bit toxic, it is an irritant. It should have evaporated off though. My point is that in theory it could hurt you in one or a few ways.
@pseudobeanmachine9770
@pseudobeanmachine9770 7 жыл бұрын
improperly cleaned glassware would be the kicker ;)
@aga5897
@aga5897 7 жыл бұрын
What kind of things do you wish to eat that are not already available to cheaply buy ? Like he says in the video, the pepper remained peppery, and the extracted crystals were pretty much tasteless.
@aga5897
@aga5897 7 жыл бұрын
Guardian of Bullshit. Confirmed.
@dpasek1
@dpasek1 3 жыл бұрын
If you don't have any extractor thimbles, you can use scrunched up coffee filters. Just make sure that the reflux condenser drips inside the top of the filter for best results. As long as the top of the filter is above the top of the siphon, it will work fine and the grind of your powder will not be as critical.
@verebellus
@verebellus 4 жыл бұрын
what about extracting the thing that makes ginger so harsh
@pegleg2959
@pegleg2959 3 жыл бұрын
Their souls? You'd probably need a priest for that
@verebellus
@verebellus 3 жыл бұрын
@@pegleg2959 I actually have the spawn of Satan in my cupboard
@mattlogue1300
@mattlogue1300 3 жыл бұрын
She wasn't harsh to me.
@weisu1427
@weisu1427 7 жыл бұрын
Seeing crystals form never gets old!
@jessivemovedude2468
@jessivemovedude2468 5 жыл бұрын
It's been two years, and there is no response from Wei. What have we done?
@ClearInstructionsOnly
@ClearInstructionsOnly 7 жыл бұрын
Instruction not Clear enough. Extracted meth, having problems with Walter White right now. Thanks Nile.
@bernardo00124719
@bernardo00124719 7 жыл бұрын
what a douche.
@nineix9438
@nineix9438 6 жыл бұрын
Clear Instruction same
@KnakuanaRka
@KnakuanaRka 6 жыл бұрын
I swear, if I had a nickel for every meth/Breaking Bad joke made on a NileRed video...
@williamackerson_chemist
@williamackerson_chemist 6 жыл бұрын
K1naku5ana3R1ka You would have become a millionaire off of his methylamine HCl video alone...
@MrDoboz
@MrDoboz 6 жыл бұрын
should have stayed away from the nazis
@Yot3Music
@Yot3Music 7 жыл бұрын
13:15 "impressive spoonflip"
@lily_skye
@lily_skye 5 жыл бұрын
The explanation of the soxhlet extractor was super cool!!! I love your channel so much~!
@MaxSeidel1
@MaxSeidel1 5 жыл бұрын
For the extraction from fine powders you may want to use a soxhlet thimble or capsule. These things leave enough room on the sides to let the solvent drain,while offering the increased specific surface area of fine powders. They are commercially available, but you should be able to make one yourself.
@EchoSiera
@EchoSiera 5 жыл бұрын
13:26 HIS FACE WHEN IT FALLS I CANT
@bigfella2111
@bigfella2111 5 жыл бұрын
Wat
@thesovietkevin7275
@thesovietkevin7275 4 жыл бұрын
Wat
@gabrieltriest3574
@gabrieltriest3574 4 жыл бұрын
Wat
@peachylyn
@peachylyn 4 жыл бұрын
Wat
@violegrace6219
@violegrace6219 4 жыл бұрын
Wat
@nunyabisnass1141
@nunyabisnass1141 7 жыл бұрын
Wow. The color, cleanliness, and order to your kitchen in this public appearance could speak volumes. I get the feeling that you had a highly structured upbringing.
@Toxis374
@Toxis374 3 жыл бұрын
8:12 At first, I wanted to note that both enantiomers are of course reacting exactly the same with non-isomeric compounds, but then I realized that Chavicine is actually a geometric isomer of Piperine.
@za.hydrohydro8794
@za.hydrohydro8794 2 жыл бұрын
I love Soxhlets 😄 They're super convenient, awesome to look at while extracting and generally have a super smart design. Only used it once tho (for piperine as well). But I used a cellulose based extraction tube instead of cotton. The solvent passes through the pepper a lot nicer and it was easier to remove the pepper after the extraction was finished.
@HuxleysShaggyDog
@HuxleysShaggyDog 5 жыл бұрын
This is late but: Use a BURR GRINDER for black pepper, or in general, if you want a controlled fineness to your grains. Blade grinders just chop in a mess.
@BJ_22
@BJ_22 Жыл бұрын
Went from food grade to making grape soda from nitrile gloves.
@FrottyZaoldyeck
@FrottyZaoldyeck 7 жыл бұрын
Can you make MSG?
@NileRed
@NileRed 7 жыл бұрын
Ill look into it. There might be an interesting way
@ender_scythe2879
@ender_scythe2879 7 жыл бұрын
Yes, make e621.
@cowboy_k3147
@cowboy_k3147 7 жыл бұрын
ahh... I see... Ramen is just the generic name for MSG
@Praxis4RageBaiting
@Praxis4RageBaiting 7 жыл бұрын
+
@Henry60217
@Henry60217 7 жыл бұрын
ThunderGirl Emi monosodium glutamate
@Kris_L.
@Kris_L. 4 жыл бұрын
I know this is years later, but I want a t-shirt that says 'Keep my Piperine Clean' . Found your channel not long ago and I love the work you do. Binge watching NileRed for quarantine. Woo!
@synthesizer8026
@synthesizer8026 4 жыл бұрын
I did a piperine extraction today with a makeshift soxhlet-type extractor. It was a simple distillation setup with a liebig condenser. I put some cotton in the bottom of a sep funnel and poured my fresh ground pepper in then placed clipped it in place of my receiving flask. Below that I had another round bottom. I would let the solvent fill up in the sep funnel then open the stopcock and drain. It takes more time then a soxhlet extractor but beats wasting so much solvent. My next purchase is a soxhlet extractor and 2 vacuum adapters to turn my sep funnel into a pressure equalized addition funnel.
@SciDOCMBC
@SciDOCMBC 4 жыл бұрын
with very fine powders, acid-washed sea sand can be mixed in with it, this allows the solvent to flow through even very fine powders, which increases the extraction enormously finely ground substances naturally increase the yield and the sea sand allows the solvent to penetrate the powder very well
@EvocativeKitsune
@EvocativeKitsune 7 жыл бұрын
Now we know you do exist outside of the lab! I'm really excited for the rest of this series.
@NileRed
@NileRed 7 жыл бұрын
ha, i do have a life outside of chem (surprisingly).
@aposvlah1855
@aposvlah1855 7 жыл бұрын
NileRed how old are u btw?
@SadMarinersFan
@SadMarinersFan 4 жыл бұрын
"I will only be using food grade materials" Procedes to mix red bull and acid to take out the caffeine
@adenosine3p
@adenosine3p 7 жыл бұрын
Now lets see piperine into safrole! You can use it to make root beer :P
@xenonram
@xenonram 7 жыл бұрын
adenosine3p LOL
@lookoutvideo
@lookoutvideo 7 жыл бұрын
"Root beer"
@MrFujinko
@MrFujinko 7 жыл бұрын
nice try, DEA
@theartofnigas3245
@theartofnigas3245 6 жыл бұрын
MrFujinko, What's wrong with a little 3,4 methylenedio- I mean root beer?
@szczurpiekielny7756
@szczurpiekielny7756 6 жыл бұрын
or piperonal from piperine
@addemater
@addemater 3 жыл бұрын
Dude, you're an inspiration. Thank you for all your videos and demos.
@glitchgaming9093
@glitchgaming9093 3 жыл бұрын
Anyone else just enjoy the fluid movement of the bubbles? its so calming!
@mftripz8445
@mftripz8445 7 жыл бұрын
Nile is too young to have all this knowledge xDDDGood job NIle, keep up the great work!
@filipkovarik4028
@filipkovarik4028 6 жыл бұрын
Lmao I thought you complimented the Piperine at 9:50 XD
@Castle3179
@Castle3179 5 жыл бұрын
I can think of other substances that might be considered spicy like cinnamaldehyde from cinnamon. Have you ever filled your mouth with cinnamon hearts? EDIT: never mind I just learned that the cinnamon hearts also contain capsaicin. However I've chewed plain cinnamon sticks before and it still burns a bit.
@nicholaswouters1203
@nicholaswouters1203 Жыл бұрын
There was a chapter in Secrets of Methamphetamine Manufacture that talks about using piperine as a starting point for making amphetamine
@drumstyx
@drumstyx 5 жыл бұрын
Your videos are so entertaining because of the professionalism in hobby chemistry -- keeping so chill about spilling most of your product!
@FrugalGarden
@FrugalGarden 7 жыл бұрын
Nile red. Please make caffeine that is food grade from coffee. I know that you made caffeine before but the DCM is toxic, maybe with CO2
@Modenut
@Modenut 4 жыл бұрын
I read somewhere that nerve impulses (such as heat and pain reactions) move at roughly 275 kilometers per hour in the body when they travel from the injury to the brain. =D
@weekendstuff
@weekendstuff 2 жыл бұрын
Cool Project :-) Thanks for showing
@ingobaby1
@ingobaby1 6 жыл бұрын
We did this in organic chemistry last fall! Was really fun to do. While checking the melting point to see how pure it was, the entire lab coughed like crazy, and one of the lab engineers had to step outside to get some air :P
@Daft_Dhwelk
@Daft_Dhwelk 3 жыл бұрын
Nigel, I wonder if your yield would be better if you had used raw pepper, soon after it's taken off the creeper? Raw pepper is dark green in color before it is dried whole. To make white pepper, the outer fleshy part, is smashed by hand and the inner core is dried. The outer fleshy part is where the heat is. I hope you can source it some day. They are plenty in Southern India and Indonesia but it is illegal to mail them across, while they're raw.
@RobMil20
@RobMil20 5 жыл бұрын
THIS is the video that made me sub. oh yea, the extracting citric acid video too. Great job!!
@Ricekrispy10
@Ricekrispy10 5 жыл бұрын
2:27 that can fit into one of my bongs 🤔 What kinda science you pullin here, Nile Edit: I saw you hold it in your hand. I don't want to see the bowl that can sit in that
@ChiralSpirals
@ChiralSpirals 4 жыл бұрын
Damn nigga hood stonks beef unit. Tripple G boiled cabbage ghetto propz. Got the hoez goin nutz pimp hat chicken feather flapper town.
@nicholashodges201
@nicholashodges201 4 жыл бұрын
Bowl? I think you mean small bucket...
@sersoft_corp
@sersoft_corp 7 жыл бұрын
Holy shit! I have that exact same coffee grinder!
@Mysteri0usChannel
@Mysteri0usChannel 5 жыл бұрын
Question: Why is pepper hot in a different way than chilis? Apparently the mechanism is the same, but the spiciness is not only different in intensity but also in "taste".
@D1ckator
@D1ckator 4 жыл бұрын
I also love the Soxhlet's extractor, my favorite method of extraction alongside with steam assisted distillation for the extraction of essential oils
@ArunaVidu
@ArunaVidu 4 жыл бұрын
Hi, If you know how, could you kindly explain how the black pepper oleoresin is made?
@D1ckator
@D1ckator 4 жыл бұрын
@@ArunaVidu Well, to be honest, I have not tried it with black pepper, and although I've seen black pepper oil extracted with supercritical or liquid CO2 (which is also a quite common method), i have no personal experience with this...
@ArunaVidu
@ArunaVidu 4 жыл бұрын
@@D1ckator are oil and oleoresin 2 different thing? oleoresin is also in liquid form
@D1ckator
@D1ckator 4 жыл бұрын
@@ArunaVidu Well, while an essential oil is a multicomponent mixture usually composed of a variety of terpenes or terpenoids and many other compounds that the plant is able to biosynthetise, oleoresin is a mixture of essential or fatty oil and a resin, and should be therefore kind of semi-solid, not an oily liquid like essential oils.
@ArunaVidu
@ArunaVidu 4 жыл бұрын
@@D1ckator Ahh thanks. but ones on the internet as oleoresin for sale are in liquid form. and they mention it as processed from solvent extraction method. I searched many times, but couldn't find any information about how to make oleoresin. So in this video of obtaining piperine, do we see in any stage, Oleoresin being made?
@Ferro_Giconi
@Ferro_Giconi 5 жыл бұрын
I'm not sure if anyone has mentioned this yet because this video is old, but being in solid crystal form may be why it was so weak. As a small bit of possibly related personal experience, I can eat a tablespoon of granulated malic acid and it's tart, but not particularly sour. But if I mix it with some water and let it fully dissolve before trying it, it gets REALLY sour. You should try this again but with a 1:2 or so mixture of crystals to water.
@mikkomallikas8362
@mikkomallikas8362 7 жыл бұрын
got to have my daily dose of chemistry
@choo9266
@choo9266 7 жыл бұрын
Mikko Mallikas Yessss
@ADRIAAN1007
@ADRIAAN1007 5 жыл бұрын
It there a reason why wasabi only has a high heat for about 20 seconds and then rapidly fades? Whereas peppers tend to last about half an hour.
@SoulDelSol
@SoulDelSol 5 жыл бұрын
Different chemical
@Sp00kq
@Sp00kq 4 жыл бұрын
Different chemical probably
@petersaburov8022
@petersaburov8022 5 жыл бұрын
13:51 nice line you got there on the table
@berniebeckerman77
@berniebeckerman77 5 жыл бұрын
The piperine isn't vert water soluble, that's why it didn't taste very spicy. You need small molecules to react with the receptors on your tongue; the crystal is a pretty stable form that's not going to want to interact with the receptor. Dissolve it in a small amount of ethanol, or try some kind of fat. Conduct your taste test again.
@fizixx
@fizixx 4 жыл бұрын
I like this part of your channel. Interesting to explore things we consume.
@ammlseri5769
@ammlseri5769 7 жыл бұрын
Extract curcumin from turmeric :)
@tonyaltobello6885
@tonyaltobello6885 6 жыл бұрын
13:28 is fricken hilarious im dying😂😂😂🤣
@Mostlyharmless1985
@Mostlyharmless1985 4 жыл бұрын
5:00 ...It’s a fancy science percolator
@TheSentientCloud
@TheSentientCloud 5 жыл бұрын
I'm excited for the Capsaicin one! I'm a spice junkie lol I've considered buying pure cap because of how much I love spice. Add a crystal to my food when 5 ghost peppers won't cut it lol
@vincedibona4687
@vincedibona4687 8 ай бұрын
I will never get used to seeing Nigel without glasses.
@jamesJohnson-qe4gw
@jamesJohnson-qe4gw 3 жыл бұрын
"It actually tastes pretty horrible.."
@ZombiecowCast
@ZombiecowCast 7 жыл бұрын
nile is cute
@guerra_dos_bichos
@guerra_dos_bichos 6 жыл бұрын
it`s kind of like seeing the new spiderman take his mask off
@soup229
@soup229 5 жыл бұрын
10/10 cute boi
@_boof
@_boof 5 жыл бұрын
NIGGA U GAY
@toiletshark6368
@toiletshark6368 5 жыл бұрын
+Sean Wilson No You(no homo tho)
@Valsorayu
@Valsorayu 5 жыл бұрын
who likes a river?!
@Hiear
@Hiear 7 жыл бұрын
13:25 - i can imagine this fat "FU*K" between shots xD
@hughmcrae3510
@hughmcrae3510 7 жыл бұрын
zalplde Who?
@muhammadosama3358
@muhammadosama3358 6 жыл бұрын
zalplde lol
@rizwannazeer7092
@rizwannazeer7092 Жыл бұрын
nigel: i will only use clean glasswares and food grade chemicals in this series. me: ok. WAIT WHAT?
@willputra19
@willputra19 4 жыл бұрын
I really love this channel. Keep up the good work.
@RustyR3volva
@RustyR3volva 5 жыл бұрын
"To help me out, because I'm lazy", made me laugh.
@BenjaminGoldberg1
@BenjaminGoldberg1 6 жыл бұрын
Your extraction device reminds me of a Pythagorean cup!
@Ealsante
@Ealsante 3 жыл бұрын
Well it does work on the same principle! As does the siphon.
@vegangelo_29
@vegangelo_29 5 жыл бұрын
"to help me out because I'm lazy.." HAHAHHA. I really love your attitude! 😍😍
@daniellynch3724
@daniellynch3724 2 жыл бұрын
You can use an adjustable burr grinder to get more precise grind size
@timelessperspective
@timelessperspective 9 ай бұрын
That last background of the Chromyl Chloride is an amazing picture. I would love to take pictures like this all day long!
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