Announcement of the 2024 Nobel Prize in Physiology or Medicine

[@미리링-b7d]

First thing I had in my mind when I learned microRNA binding in post-transcription process was feeling a opportunity at the dooorstep. Thank you Prof. Victor Ambros and Prof. Gary Ruvkun

[@CoolKid-q3d]

impact of post-transcriptional gene regulation extends across medicine, agriculture, and fundamental biology, shaping our understanding of gene expression and its role in health and disease.

[@cristianasensio3038]

The discovery of "alternative mRNA splicing" is still deserving a Nobel for the increasing importance the mechanisms has in health and disease.

[@abderraoufbouchene1737]

The first 2 questions from the audience are quite interesting!

[@pantrivedi]

Congratulations to Prof. Victor Ambros and Prof. Gary Ruvkun for their paradigm shifting research!! What a moment of joy for all of us who work with microRNAs.

[@musangu_m3]

A warm congratulations to the two Laureates! Such a wonderful novel research and study.

[@SanjayRaji-lq5mi]

Congrats Dr. Victor Ambros and Dr. Gary Ravukun from Helpman Technologies. May your work lead us into a new beginning of better understanding of the Human Physiology a bring more simple solutions in Medicine - Sanjay ❤❤❤

[@المعرفة-ص5ن]

I'm studying medicine, and I wish getting it one day❤

[@hamza_osteoblast]

I'm a med student too, can we connect?

[@lubondochilekwa]

Work hard and it will be yours one day ❤️

[@jimtgee]

Congratulations to Gary Ruvkun and Victor Ambros, great work! Especially your years of research collaboration....and "paying brute attention to details!"

[@julianopacagnelli2770]

Congrats Victor Ambros and Gary Ruvkun! Fantastic!

[@dhirendraacharya7735]

Congrats Victor Ambros and Gary Ruvkun

[@eduadda.1864]

One question from my side , is Now if we able to synthesize microRNA, how it would change the medical sector ?

[@Itsnotfogell]

It is posible to synthesise microRNA outside the cell. As it has the ability to control gene expression, it can be used to develop new therapies, improve diagnosistics and make gene therapy better. These are just from the top of my head. May be someone else can add to this.

[@lakshyakumar3791]

I think it would lead to potential treatment for diseases thay seems incurable like cancer or AIDS as we can study mirna as they carry genetic info .And studies reveal that these genes also can lead to cure of some diseases

[@المعرفة-ص5ن]

@@eduadda.1864 the effect isn't direct

[@familiegeier4828]

Yes! To my experience the problem is the quick degeneration of microRNA. N1-Methylpseudouridine or pseudouridine (5-ribosyluracil, psi, pseudouracil) could help (Last years Noble Prize in Medicine or Physiology for Katalin Karikó and Drew Weissman!) to overcome this problem; however, adverse effects need to be considered carefully. Even treating warts with microRNA would be of interest, however I did so with formic acid this morning; I hope formic acids works. Yours Stefan Geier, Haidholzen 🙂🙂

[@Mokhtaramara2996]

The general principle: Synthesis of microRNAs that induce desirable activities that was inactivated or to inhibit indesirable activities that are activated by diseases.

[@PrabhakarKrishnamurthyprof]

It is a great step for humanity. Happiness took over me for the prize of greatest scientists of the 21st century.

[@maverick_monkey]

In case there are people knowledgeable about this here in the comments: about the first question from the audience - since all our cells contain the same DNA, i.e. the same genes, including the same genes which code for microRNAs, how is it possible that the translation of microRNAs is tissue-specific? Wouldn’t all the microRNAs still get produced in all cells? From the committee’s answer, I just understood that different microRNAs do indeed get produced in different tissues, but I did not understand _why_ that would happen. If there’s some literature you could point to, or a popular science article that explores this, I’d be grateful :) Thanks in advance!

[@batchrocketproject4720]

Nice summary of fundamental discovery science where study of phenotypic variants of 'unimportant' organisms led to an entirely new avenue of research on the control of gene expression in all organisms. Congratulations to the laureates, and thanks to the committee and speakers.

[@-AkhilTej-]

🎯💎🏆 Great insightful & fruitful video 🏆💎🎯 लोकः समस्ताः सुखिनो भवन्तु ( May all beings lead prosperous life across Globe 🌍 )

[@appsenence9244]

Absolutely amazing 🎉 Congratulations to the laureates!! I love science!!

[@PHYSICSEXPLORER-bx5qi]

Wow great discovery but yet to discover its applications. 🎉

[@henrydickerson9776]

That's the thing about pure research: it often results in unexpected future research and invention.

[@zita_sharo]

I have heard of the existence of MicroRNAs for a few years now. What I heard is that not one fully understood their function at all within the Dogma Central of Biology. With this Nobel Prize, I believe it is meant that that they elucidated the mechanism of action of microRNA's in post-transcriptional gene regulation because microRNA already were known.

[@azzamohamed6186]

Congratulations...I am looking for more explanation in medicine..to easier understanding,diagnose&cure

[@sajiruddinsk8129]

Thank you so much, Jarur, Murshidabad, WB, India🇮🇳.

[@AnaMon-ks1wp]

Excelent! CONGRATULATIONS Dr Ana Mon from Argentina

[@manaskhatua5965]

Respected sir that I have gathered the knowledge from different books there is no knowledge about the research of systematic influence of external stimulii over the parental genes which is most effective

[@jaekae-u3k]

Everything attached to this finding should have a socially conscious profit margin.

[@MMMM-sv1lk]

Congratulations 🎉 micro RNA for the win... 🌹✨🏆🎓❤️

[@MohamedMarawan403]

A very great event with the best wishes for scientific results, more research and useful scientific progress for humanity

[@cavadmmmdov9470]

Graculation for every Doctors

[@raeflex1538]

Congratulations to the 2 laureates. We were thought about miRNAs last year!

[@minendrasamarakoon8139]

Congratulations.... it s a dream of any Science student...

[@trevorsakameya]

Amazing. I am utterly amazed.

[@knirmel]

Absolutely fantastic… curiosity and then making sense over years of work.. and good collaboration..Congratulations !!

[@sachinkarp1802]

Congratulations Both of you Sir

[@MoosakuttyThandthulan]

Fantastic!, congrats Dr.Victor Ambros and Dr.Gary Ruvukun!. 👏👍👌🙏💞

[@azibghadi]

Dream of every science student.

[@manavsharma8077]

This is Science 👏

[@LumTheAlien]

This is fascinating, the mRNA regulatory pathway could still have many applications we have not yet discovered.

[@StoryIcan]

similarities in the behavior of some mobile elements how do they compare with retroviruses (RV) are small-stranded RNA viruses, mainly found in mammals which are capable of covering themselves with a protective membrane and infecting individual cells of the same or different hosts. some RVs carry cancer-causing oncogenes.

[@Sofie-o4d]

Congratulations 🎈🍾🎊 🎉🎉🎉🎉

[@oladejiislamiyyah1029]

Congratulations

[@theenergyoftheword]

Congratulations!

[@AmitKumarHere]

Victor ambros and gary ruvkun congratulations 🎉🎉

[@JaxonTumusiimeJr]

Hi... Jaxon Tumusiime Jr from Lira University Uganda

[@zita_sharo]

I see now, Dr Victor Ambros and Gary Ruvkun worked and discovered microRNA and its role since the 90's.

[@nyujun]

Prize long over due... for this research

[@chinmaykarmakar3766]

Congratulations স্যার.. এবারে নাম গুলো মুখস্থ করছি আর কি😅

[@abhisheksoni9774]

Congratulations :-)

[@Laniakea-no8eb]

Congratulations !

[@hirakchatterjeehere]

Congratulations

[@MaryemIsmail-rn2wb]

Congratulations,I love it

[@suryakantkadam9097]

Great work.......... Ss

[@hakikatali384]

Congratulations ❤

[@karthickprabhu5570]

Congratulations 🎉

[@Ahmadaliexplore]

grattis till er båda🎉

[@volkerl.314]

When will these Swedish guys learn how to pronounce the word "questions"? This is MY question!

[@ChandimaKiththanbahu]

Medicine❤

[@Opregricoso]

Impressionante! Meus parabéns ao laureado 🎉🎉🎉

[@jeremysmith-k4v]

respect🎉

[@mokhtaramara1597]

The Prize must help science to enter a novel era ... subjects like "conscience" ,new Theories in biology completing or replacing some areas of Evolution must make a revolution and be rewarded.

[@OussamaHaigoune]

يسعدني ان أتابع هذه المسابقة بكل فخر و إعجاب

[@劉安安妮]

God arranges gene and makes it function, and V. Ambros and G Ruvkun decode it.

[@DineshKS28]

🙏

[@hectorgamino]

👍

[@safamaroia2753]

👏👏👏👏

[@Jonaerima]

🫡🫡🫡🫡🫡

[@keepcalm7453]

❤❤🙏❤❤🙏❤❤🙏❤❤

[@conscioustrader6007]

New realm of gene regulation ❤

[@francoisebianchi7282]

Toujours les mêmes vendus aux labos plutôt qu'au service de l'humanité.

[@abheekg]

<a href="#" class="seekto" data-time="1404">23:24</a> difference between micro rna and m rna kzbin.infoUgkxLguLj7pVbksRHrFFnKw0LCErmP77AX7x?si=J0mwi65H-Bq_YkdA

[@AfitoLuciano]

Congratulations!

[@3rddegreeyt144]

Congratulations

[@sparshhardik]

Congratulations!

[@aadeshraj450]

🫡🫡

[@SergeLkb]

Congratulations