Novel Ultrasound Breaks Blood-Brain Barrier to Treat Glioblastoma

Roger Stupp, MD, and Adam Sonabend, MD, physician-scientists at Northwestern Medicine, discuss a novel skull-implantable ultrasound device used to open the blood-brain barrier to deliver immunotherapy and chemotherapy for glioblastoma treatment. The results of the first in-human clinical trial showed a remarkable four- to six-fold increase in drug concentrations in the brain, indicating that it may revolutionize the treatment of neurological diseases.
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