Friedreich’s ataxia - causes, symptoms, diagnosis, treatment, pathology

What is Friedreich’s ataxia? Friedreich’s ataxia is a disorder where there’s a buildup of iron that damages various organ systems - in particular, the nervous system gets damaged which causes ataxia, which is when the muscles don’t move in a coordinated way.
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[@zeus_goes_brrr9844]

Who's here to know what Kaori(Your Lie In April)'s disease was?

[@supakaioshin]

i legit just finished watching it i came here to find out about it

[@zairiq]

"cries in love's sorrow"

[@sku11exz]

me 😢😢😢

[@sherardmesurado1593]

Me

[@estebancitosolanito7180]

Im gonna cry

[@mangadatoga]

uptdate: Omaveloxolone has been aproved for treatment of FA

[@shandra5923]

I have this rare disease. It's pretty cool to see this channel make a video about it. Yay for awareness :D

[@profirhuma]

Wish you a speedy recovery and the strenght in standing against your challenge

[@carinareann9590]

@@profirhuma it doesn't go away and their s no cure yet

[@karthikk842]

What are your early symptoms How is your health now I'm unable to walk properly from past 4 days Taking verbet 16 Still feeling dizziness Please share your experiences I'm 26 years old

[@profirhuma]

@@carinareann9590 sadly I know, I am a physician

[@lea-ks9nq]

I have a rare condition that only 50 ppl in the UK have.Wish a channel like this would talk about my condition

[@_E____]

I came here for Kaori(Your Lie In April)

[@javieraravena3972]

me too

[@gojos.1stan]

Me too

[@EmmaVolturi]

@@gojos.1stan Same

[@depressedguywhodoesnttalkt4676]

Same bro i'm still healing...

[@shxrmeen5631]

Same

[@Gabe-sp8ml]

So this desease caused the death of the most beautiful violinist ever...

[@miku_is_my_waifu9871]

Lesson learned, don't talk to blonde violinists

[@fairuzbpn3840]

@@miku_is_my_waifu9871 unless, if you are some Men with glasses, can play the piano. And very quiet person

[@Lunakate243]

U got me, c'mon u know my mind

[@SaifRehman-ir7mq]

Would have good if U accept Islam the true religion and if then U died will found the other world called heaven where U will be blessed with every blessing of Allah

[@Koro_senpaii-e4b]

And she lied to a boy with glasses.

[@rin3257]

Your Lie In April....

[@Lunakate243]

U read my mind 😎

[@saradisabatino3708]

im scared. i still havent finished your lie in april and the comments are already making me cri

[@malikgetthatguap4118]

appl3 b0b m Welp ik u cried

[@signzzz1949]

Saikik

[@kuyaklyne]

Did it reach her ? 🥺

[@chosenstrong9539]

Ooh~ good comment and good pfp

[@Lunakate243]

It did! 😔

[@miimiilewd7782]

Yah...

[@ezekielyoingco7683]

Kaori :( :(

[@khraysa]

kaori tho :(

[@miywzono8652]

i miss kaori:(

[@EmmaVolturi]

Me too I miss Kaori

[@athenabcde]

Me too…

[@Lunakate243]

:'( i miss her she doesnt deserve to die because if this illness

[@markcayanan8399]

Everyone misses Kaori ☹️

[@tear6134]

:(

[@mollymills6133]

This disease runs in my family, which is why I’m here. But someone please tell me who Kaori is that I’m reading all these comments about.

[@luvmads9396]

kaori is from one of the best anime’s ever! it’s called your lie in april. It’s so beautiful!!! i watched it and could not stop crying! this isn’t a spoiler, because it’s shown throughout the show but she suffers from this disease.

[@med6389]

He wanted to die, She wanted to live, He lived for her, She died for him. "She" is a character from an anime called Your lie in April. She suffered from this desease and in her remaining days, she succeeded in making the life of the person she loved to be reconsidered again! And when he got out from the pit of sadness, she died!

[@liesdamnlies3372]

@@luvmads9396 …well don’t worry…the other guy spoiled it for you…

[@luvmads9396]

@@liesdamnlies3372 haha!! ^^ yea :)) but it’s ok for me since i watched it years ago

[@markmartin2413]

He cured me few months ago

[@mykelboy7764]

Kaori Miyazono.. She choose to undergo the slimmest chance to be able to stay and be with Kousei in good health, but fail.. The author was selfish..

[@miimiilewd7782]

Yah...

[@azone1465]

M o s t viewers are learning K a o r i' s disease which is I the same R.i.p kaori

[@miimiilewd7782]

Yah...

[@areejps]

this is strange how kaori has Friedreich’s ataxia and the all anime was talking mainly about Friedreich Chopin symphonies

[@davidkillebbr1902]

lol

[@meowpluff6035]

Lol...I like your PFP....It's Akito 🤭 I like her as well🤫🤫

[@areejps]

@@meowpluff6035 akito, she is my dady i love her 😍😍

[@meowpluff6035]

@@areejps I know right! I love her as well! She's so cool! But there's a lot of fruits basket fans who still hate her😒😒

[@areejps]

@@meowpluff6035 I do not blame them, she abused them a lot, but i love people who change for the better and try to understand the world around them better, she worked a lot on herself to change and still feel guilty about what she did, she apologize and respect, becsuse of this i, i respect her too much. 😍😍❤️

[@mattyweini00]

Just studying for the medical biology exam and watching Your Lie in April at the same time... I miss her so much:(

[@tracypeacock842]

My son has this … I am so afraid for him .. he has had it all his life but wasn’t diagnosed until he was 17 .. he was able to walk until he was 22 and is now in a wheelchair .. he is at peace with his disease as his mother I am not .. but I am very proud of him ! Ty for the video

[@osmosis]

Hope our video was able to help, Tracy. Your son is such a trooper! ❤️

[@christopher4443]

I love how YLIA basically became a Friedrich's Ataxia awareness show

[@jomybaby22-gaming]

I wish the creator just said the disease out loud after the anime ended that way, more people become aware of it

[@nexusgaia]

I never thought I'd see someone talk about that here

[@samuelcohen2362]

Roses are Red Violets are Blue I came here for Kaori How about you?

[@user-bx9kf4gb6d]

KAORI NOOOOOO!

[@liamzgaminghd8683]

I just want it fuckin cured because I have a life ahead to live and I don’t want to spend it all having difficulty balancing and having to use a wheelchair, I’m 18 so I want to be going clubbing and off to raves, festivals and parties, I don’t want to spend it all watching other people enjoy there lives and me being told to sit back in a chair and to stop complaining it doesn’t work like that, there has to be a very potent interventional drug out that will make to this condition, a good change

[@robertkirby8685]

I don't blame you, my mother also has friedreich’s ataxia and it's progressed so bad that she's dependent on me and my father to help her move from her bed to her wheelchair and vice versa, and believe me she wishes she could walk and do other activities without the help from others. Here's to hoping by the time you get to be her age a cure for it has already been discovered.

[@tonypae6151]

Give me information about treatment so plz i want ur help my mother suffer ataxia so help me give information about cure i dont know about treatment

[@thereactiveindian4755]

@@tonypae6151 tell her do Yoga and its called Pranayam you can search on google, how to perform it. it will help her to deal with it. Yoga is very ancient and it has good effect on health. you can connect with me.

[@RohanSinghal-ob7zu]

Miss you kaori

[@droutlier]

Thanks for explaining this condition in the most simple manner to the students.

[@minimedlessons]

I was just looking at this diagnosis! So interesting. Happy to see your video. Thanks for all the quality content!

[@savyer2813]

Came here for kaori in your lie in april

[@korewatorika]

Father of this child at 2:00 hasn't his leg, thank you for this detail

[@acciolupin]

Thank you for spreading awareness. I've had this since I was 12, and it's really nice knowing people are talking about it.

[@osmosis]

Glad to help in our little way. 😊

[@girdhar3224]

How r u now

[@teamactsusanatrainings8401]

I was here to check about Kaori’s disease coz that movie broke my heart so much! But knowing the manifestation of this illness, if anybody who has this illness, mitochondria can be supplemented with Co Enzyme Q10 + ALA to recycle the Energy in the cells and muscle functions can be supplemented with Calcium to manage the weakness and contraction of it. And the oxidative damage can be managed by Anti-oxidants.

[@teamactsusanatrainings8401]

@Ameri Can Alpha Lipoic Acid

[@willyfrankenstein6595]

My theory has always been that she survived the surgery but that she did not wake up from it. Instead she fell into a coma that her doctors didn't think she would wake up from. Which is why the letter was given iń the graveyard but the view was far away. Too far to see any specific gravestone. The parents are making arrangements for her in case she did not come out of the coma.

[@stampydragon2739]

There is a surgery that can reverse the loss of control in the limbs and buy you more time but it’s not recommended due to the high chance of complications leading to death

[@16-tranhoanghungthinh80]

Kaori Miyazono is inside that unfortunate part.

[@justahumanwithamask4089]

So Kaori was doomed from the start, damn this is even more sad

[@16-tranhoanghungthinh80]

The thing that took Kaori away too soon.

[@jdogthesmegmagod5435]

I stole your thumbnail for my English project I hope you don't mind. It's great to see people spreading awareness for this rare disease!

[@Anarchy2324]

Do you mind providing some of your sources for this video? I'm currently doing a school assessment on the disease and would love to know your sources!

[@osmosis]

Hi! Kindly send us an email ([e-mail]) and our team will be glad to assist you with this! 👍🏼

[@JordiLicenciado]

Tomorrow there's an exam about this in my faculty! so grateful :)

[@Booli......614]

You are my favorite 😍 KZbin channel because I love biology so much thank you

[@maddiekannady2855]

I have FA and this video does a great job of explaining it!

[@markmartin2413]

He cured me few months ago

[@maddiekannady2855]

@@markmartin2413 of what?

[@markmartin2413]

Of ataxia

[@maddiekannady2855]

@@markmartin2413 why are you saying that on here? Did you even watch the video?

[@markmartin2413]

What do you mean, I was only telling people that there is a herbal cure for ataxia

[@salmazain5013]

As always perfect and on spot presentations. Can you add some of clinical examination findings. So it can helps in the clinical practice. Really appreciate the effort 💕👍

[@osmosis]

Thanks for the feedback! I've relayed your request to our team for consideration. 😊

[@bakiheni4775]

Hi! Can you please make a video about nystagmus? 🤗

[@user-mw2wn4ix2s]

A video about squint will be more useful ....

[@سامي-ك2ق]

Subscribe for u , and like ,u r the best ,,,blz try to continuo in sub aarbic,,,,,thank u bro

[@dennismarshel7040]

I'm getting tested for Ataxia, I can barely walk and have had balance and walking problems my whole life and just thought that was just me and dealt with it . I need a cane/walker to get around. I would just like to know what I have wrong for once in my life.

[@XiaolinShwdownKid98]

I have this horrible disease and it has ruined my entire life. So many things I’ll never be able to do again. Imagine the looks and pity I got using a cane in high school. Now I’m 26 and I’m wheelchair-bound. I mourn my independence every day. It all started when I was 11. Sometimes I wonder if it’d be easier if I was born with the condition rather than to have grown up as a perfectly normal and active kid. It’s devastating to think I will never have that back. I will forever hate this stupid disease

[@AD-zs3ey]

Whilst they are researching and coming up with solutions why not do or recommend the following: - Lifestyle that helps to fight off free radicals - Minerals and supplements to increase the levels of frataxin to support the mitochondria e.g. Calcitriol Also, what about the use of stem cells? Although I imagine the cells will need to be free of the abnormality in the gene sequence. 🤔

[@anneliselim602]

The saddest part is parents will blame themselves for these genetic disease

[@XiaolinShwdownKid98]

Mine do

[@tryhappiness2725]

What’s the difference between freidrich’s ataxia and Spinocerebellar ataxia? I watched the story of aya kito and became curious as it was mentioned she had spinocerebellar ataxia.

[@manelabachi8943]

Friedrich's ataxia is a type of spinocerebellar ataxia ( ITS cause is genetic) and there are other types which aren't genetic .

[@chosenstrong9539]

Your lie in April If u know u know

[@minniesmomma6374]

My best friends son has this. When he was a small child she took him to the doctor because she felt ther was some sort of a neurological problemwith him. He was clumsy and his speech was slurred. They told her he was lazy. Years went by and he got worse. She died of breast cancer not knowing what was wrong with him. Eventually he had a diabetic attack of some sort and went to the hospital and they diagonised him with diabetes then he had a heart problem and a doctor finally recognized that symptoms to be Fredericks Axtaia. Long story after that and he went in a wheelchair and now is in some states of facility. His dad abandoned him at the age of about 19. So I don't know what happened to him. Very sad story. Much more to it.

[@markmartin2413]

He cured me few months ago

[@uddamsingh1528]

My aunty had the same disease and after that both of her son had this disease. Sadly, they all fought with this and ended with deaths only. More sad, now her grandsons have the same disease and almost on death bed😥

[@googleuser1416]

@@markmartin2413 what is the cure? How can I contact him?

[@markmartin2413]

@@googleuser1416 click on the link close to the name or search for Dr nafuar

[@kinggeorge7758]

design therapeutics

[@greamorous2327]

i read it friedrice :v

[@PandyJan-xq4hg]

I am friedreich ataxia patients please help me

[@esmailhosene6630]

لطفا دوبلہ فارسی ھم بزارین

[@danielaalves4675]

Minha mãe teve há 30 dias com dor persistente ... Agora voltou aparecer bolhas de novo

[@marialuciagranadodepaduama5069]

O herpes atacou minha virilha: estou tomando aciclovir. Faz 1 semana e a dor é intensa. Gostaria de saber se existe pomada analgésica para o herpes

[@heloizedanielle7671]

Pode tomar a vacina tomando aciclovir e quem tem menos de 50 anos? Pois as lesões acontecem semanalmente e só não aparecem se estiver tomando esta meditação diariamente.

[@salvandorum]

pronunciation is incorrect

[@rosefernandes5071]

Dr eu tô cm essa herpes zoster já secou as feridas mais dor é insuportável isso não tem fim socorro Dr

[@nicolefranaszek660]

The close captions do not follow the video super well. May be helpful if you can change them to fit better.

[@olegasav907]

Alex Ataxia Зробіть передачу про лікування GRISPR SCA.

[@lt35phila]

What is the genetic advantage to this?

[@vananhtran4994]

What do u mean?

[@francben1649]

@@vananhtran4994 What I'm saying is that FA is so devastating that it raises the question of how can it be passed on through generations? There must be a genetic advantage. Of course not all mutations are harmful, and the occasional fitness increasing mutations drive adaptive evolution. In this issue Orr (2010) points out how some intriguing statements can be made about advantageous mutations beyond the fact that they are usually rare and difficult to observe. They include (i) back mutations that occur if a large enough number of slightly deleterious mutations was previously fixed, possibly at a time when the effective population size was smaller (Charlesworth & Eyre-Walker 2007), (ii) compensatory mutations that at least partially repair some harmful effects at the molecular level (e.g. Burch & Chao 1999; Innan & Stephan 2001; Kern & Kondrashov 2004), (iii) quantitative trait mutations that can either increase or decrease the value of a trait with an impact on fitness (e.g. Keightley & Halligan 2009), (iv) resistance mutations that are part of biological arms races between hosts and parasites (Hamilton et al. 1990), and (v) mutations that enable a species to start expanding into a new ecological niche (e.g. Elena & Lenski 2003; Bergthorsson et al. 2007). The frequencies and DMEs of these groups are probably very different and their prediction and estimation are likely to be fruitful fields for further research.

[@AoiHime-3012]

@@francben1649it’s recessive genes, both my parents are carriers (have one normal gene and a FxN gene of this disease) and they don’t have symptoms if they’re a carrier. i had receiving 2 disease genes from both parents to develop symptoms of FA (becoming FA’er with 25%), 50% the kids are likely the same as the parents who are a carrier of the disease gene. 25% receive both normal genes, not FxN genes and no symptoms of course.

[@litondas7646]

Ni e

[@midom2851]

😢😢

[@yessi9078]

Mmm ya

[@onurege9256]

Bruh i was watching this video for my neurology make up exam in June. A moment ago i made a diagnose of this ilness in an anime character...I dont know what to say

[@vananhtran4994]

Ur lied jn april?

[@onurege9256]

yep@@vananhtran4994

[@AoiHime-3012]

@@onurege9256oh right, i also have FA. i was diagnosed at 16 too. Sorry i haven’t used youtube much

[@rehababdelbagi]

thank u so much for this clear simple explanation ♥

[@osmosis]

Most welcome 😊

[@Ms20326]

Excellent explanation 👏

[@osmosis]

Glad you liked it ❤️

[@bernadetesaccon2543]

Começar o tratamento com antibiótico no sexto dia do aparecimento vai resolver?

[@vananhtran4994]

No

[@taashichoudhary2842]

Superb method of teaching

[@skylerkaus8613]

My little sister has the disease

[@IceQeen1011]

Bio student here, very helpful video thank you!

[@osmosis]

🙌🏼 Always our pleasure to help! 🙌🏼

[@jermm2183]

Doing a project on this in chem. Thanks for the easy to understand summary :)

[@osmosis]

You're welcome! Pleasure to help! ❤️

[@rd5047]

My girlfriend have this disease.. idk how many days she will survive

[@akhigbegodstime]

I know of someone who can help your girlfriend get rid of this disease

[@akhigbegodstime]

Message him on Whats App"""...

[@shaiklathifpasha9127]

I have this deaseses

[@NicodemusBenaya]

Hi, hope you have speedy recovery even if the disease doesn't have known cure yey

[@mariadonadex9418]

1 month ago I was diagnosed with CANCER in 2020 and I have tried everything I can to cure myself, but all to no avail, until I saw a post in a health forum about a herbalist who prepared herbal medicines to cure all kinds of diseases, including CANCER, at first I doubted if it was real, but decided to give it a try, when I contacted this herbalist through his email and he prepared me a herbal cure for CANCER and sent it to me through the company's service UPS delivery, when I received this herbal cure. , gave me step by step instructions on how to apply it, when I applied it according to the instructions, I was totally cured of this deadly disease within 5 months of use, I am now CANCER free, all thanks to Dr. edosa. you may also need his help.

[@drusillakhundrakpam3249]

Don't worry I have that too

[@olaebrhem5641]

Osmosis is always the best 🎉💕😻🙏

[@osmosis]

Thank you, Ola! 🥰

[@carinareann9590]

My sister has FA and scoliosis

[@amnaafaque6603]

Best explanation

[@fergiejohnson633]

Osmosis you are great!

[@poojagupta6333]

Thanks

[@Blueseegull]

Is coQ10 good for ataxia patient?

[@bethvond9791]

I think so. My sister always used it.

[@tonypae6151]

@@bethvond9791 plz i want to know about treatment beacause my mother suffer from ataxia so plz help me

[@summerfunrides]

@@tonypae6151 to many people selling fake information on a cure but I’m sorry to tell you , there is no cure. You can take vitamins which is good for anyone. They can exercise which will keep their strength up but there is no cure like special tea or pill. It will only progress. Yes this is sad!

[@buddistjejus5825]

00:01 2:00 4:00 5:00

[@natasha1394]

You are such a great channel 💓

[@osmosis]

Thank you so much, Natasha! 😊

[@elisabethcostamaia5022]

Boa tarde! É contagioso?

[@goldendoodlelover6775]

Nope not contagious

[@nishaniusmle4248]

Great ...

[@aspecreviews]

Sydni Dupre? Anyone??

[@VanAnh-qm5cx]

yes her,olivia and kelly mine too

[@thuthaopham4115]

Hi

[@duynguyenquy7753]

Hello

[@saaratsathoo8366]

Awesomeeeee

[@workingclassdoctors]

Nicely explained 👍

[@osmosis]

Thank you! 🙂

[@workingclassdoctors]

@@osmosis keep Shining and keep going))).

[@ajaulino6043]

My sister has this disease and I did not know much about this. I was making fun of her for how she walks until I kinda found out more about it. Its very sad because the corona virus she can’t go to physical therapy. If anyone knows how to help please reply to this message and stay safe ❤️

[@thereactiveindian4755]

hi AJ Aulino, i am from Mumbai India, my sister has the same issue, it is genetic you must be aware. let you sister do yoga let her Do Shirsasan Yoga which is good for brain cells. we can connect. Where are you from?

[@1987rijju]

@@thereactiveindian4755 I was suffering from this disease and now I'm 70% cured

[@so-la3062]

@@1987rijju what did you do please to help? Thank you 😊

[@SSurfs]

@@1987rijju HOW

[@balanchaevtukuncho3660]

Can you translate these videos to another languages like Russian...? It would be great!

[@kaladharyadhav7697]

Jai telangana

[@whosyourdaddy4579]

Not pronounced A-taxia! Pronounced a-taxia, with a soft "a" sound...Please, if you are presenting...learn proper pronunciation!

[@miimiilewd7782]

Was too late for heal it....

[@goldendoodlelover6775]

I have FA and this is a really good explanation on like a scientific standpoint. I’ve noticed that a lot of people are hear from your lie in April, and I’ve not seen the show but as far as I know the character with fa dies from it. And I just want it to be understood that fa doesn’t often kill people, although like any disease it can but is pretty rare. Idk I just want people to know that although fa makes life challenging, people like me and my sister and a lot of people with fa survive! 🫶🏻

[@vananhtran4994]

Can we talk i have fa too, and recently diagnosed with it…

[@justahumanwithamask4089]

She actually didn't die from the disease, she died undergoing the surgery to treat the disease. You should watch it tho