Oxygen Hemoglobin Dissociation Curve Explained Clearly (Oxyhemoglobin Curve)

Understand the Oxygen Hemoglobin Dissociation Curve with this clear explanation from Dr. Seheult of www.medcram.co...
This is video 1 of 1 on the oxygen-hemoglobin dissociation curve (also called oxygen dissociation curve and the oxyhemoglobin dissociation curve).
Speaker: Roger Seheult, MD
Clinical and Exam Preparation Instructor
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
MedCram: Medical topics explained clearly including: Asthma, COPD, Acute Renal Failure, Mechanical Ventilation, Oxygen Hemoglobin Dissociation Curve, Hypertension, Shock, Diabetic Ketoacidosis (DKA), Medical Acid Base, VQ Mismatch, Hyponatremia, Liver Function Tests, Pulmonary Function Tests (PFTs), Adrenal Gland, Pneumonia Treatment, respiratory failure, anemia, and many others. New topics are often added weekly- please subscribe to help support MedCram and become notified when new videos have been uploaded.
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Recommended Audience: Health care professionals and medical students: including physicians, nurse practitioners, physician assistants, nurses, respiratory therapists, EMT and paramedics, and many others. Review for USMLE, MCAT, PANCE, NCLEX, NAPLEX, NDBE, RN, RT, MD, DO, PA, NP school and board examinations.
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Produced by Kyle Allred PA-C
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[@JustPiichi]

This helped me so much.. I could cry. Thank you from the very apex of my heart.

[@bubbleminho9092]

JustPiichi Apex 😂😂😂🤣🤣🤣

[@rezaayoubi9147]

Lmao

[@_yadavbrijesh2274]

You mean atrium?

[@sehamali5149]

jeshedu Yadav No , when you look at the heart from anterior try to look at the very lower left part (the left of the cadaver not your left) and the curved point is the apex , you can also google it

[@MrJoeldlawrence]

Makes you wonder if the people writing the textbooks are in the right line of work.

[@onikehinde8930]

Wow, understood it in just 8 minutes and I found it so hard to understand my Professor who wasn't explaining it in details. Bravo

[@Medcram]

Glad it helped!

[@KongRuPanda]

FINALLY A SIMPLE EXPLANATION!! I couldn't study this curve for weeks and now that I'm cramming for my exam, this lecture helped a lot. Especially when I saw how the curve is drawn and which side is which with the factors affecting it. Thank you so much!

[@jmcmanus1803]

Ive reviewed this concept every few years and its never stuck, but I think it will now--the way you tied in the muscles and lungs to the features that cause the curve to shift was extremely effective! Thank you for sharing!

[@iiBDRq]

Man! I’ve been struggling to understand that curve until I reached this video, it really helped me. Thank you very much.

[@erinmedina6286]

Thanks! I had forgotten the small details from undergrad, I also didn't feel like getting up to get my Biochem book.

[@roseline2564]

Simply wonderful! I was struggling with this concept for days but understood it in less than 8 minutes after watching this video, thank you!!!!!

[@Stereotactic_Shwermaectomy]

If you're ever a Program Director, I want to be in your program. Goodness gracious how you take a ridiculously explained concept in medical school and make it my.....mastery topic.

[@rimeln6443]

thank you soooo much! I don't understand why lecturers at uni waste a whole series of 5 lectures going through something that can be explained well by you in less than 10 minutes :') absolutely wonderful

[@Medcram]

Apni Rimzolaa Thank you for the feedback

[@boarder721]

Randomly found this.. and I work with this MD. Very good doc.

[@Medcram]

Thanks for the question. I actually said that RBCs have a bulge in the middle because "they've lost their nucleus" (not elastic nucleus). Hope this clears it up.

[@irenp8550]

Great explanation and diagrams. I know this comes 6 years later, but can you please tell me which program or tool you are using in the video? (I mean, the blackboard thing, how do do it?) Thanks a million for your help :)

[@minimus.saevus]

I just watched 4 videos on this concept and this is the only one that my brain understood so thank you

[@Maria-it3ee]

Just found this channel while studying for a biochem exam... very helpful I was able to follow along with my note and this video just made things a little bit clearer for me!

[@gaferg1]

In the past, I've always associated a shift to the R or L from normal as a pathologic process and not a naturally shifting occurrence throughout the body. Thanks for the clarification!

[@Medcram]

Thanks- We hope to make difficult concepts come alive. Glad to clarify the textbook info.

[@nataliehill663]

Working on my NP and your videos have undoubtedly been my saving grace in pathophys. You are a wonderful, wonderful teacher and I'm sure I can speak for many of us that we are so thankful to have educators like yourself. Thank you!

[@Medcram]

+Natalie Hill Thanks so much, glad the videos have been helpful

[@edwardsarfo2755]

No one explains it clearer than you do. Concisely great lecture !

[@mmaggi05]

I like the way you connect ideas together.

[@depyification]

NEVER EXPECTED THAT THIS COULD BE EASY TO UNDERSTAND!!!!!!

[@The743837]

You have an absolute gift for explaining complex things in a easy to understand way! Thank you!

[@louiscastro2701]

Thank you! I was struggling to grasp this concept from my lectures and reading. Lifesaver!

[@samahsamah4981]

Your videos are the best thing that happened in my life!!!!!!

[@icejunki]

As we have come to expect from this channel. Something that can be made to be understood in 8 minutes. Time to go put it into practice.

[@MrCEPPaulT]

Very helpful and applicable to the Paramedic getting ready for Critical Care Certification exams.

[@bee1zebub]

not trying to go for med school at all but currently in a biochem course and this video was very helpful. thank you!

[@BridgetteWhitney]

This video clarified a lot for me. We are learning about it in nursing school right now and we know how important this will be in practice, so understanding it fully is imperative. Thank you for making the video!

[@ZakiZaili]

Thanks, simple, and easy to understand.

[@nishant3445]

Sir....you are teacher of the teachers...lots of respect for your fablous teaching...

[@kcarreiro1000]

This video is gold, pure GOLD.

[@randolin1]

Elegant explanation on hemoglobin-oxygen dynamic shifts. Thanks a lot!

[@Rottingboards]

This is what teaching is all about! Thanks, your knowledge kept giving me positive cooperatively in my brain memory cells.

[@sparklingmoon8268]

only spent 8 minutes to recall everything thank youu!

[@clowie299]

loves these short and clear videos

[@FuckinFr]

My MD told me my O2 hemoglobin saturation was lower than it should be, but couldn't explain well what that meant. Your lectures have been helpful in understanding what that meant.

[@Medcram]

Damn the French Glad the lecture helped- thanks for the feedback

[@portarican82]

Beyond helpful and insightful! You have my very enthusiastic gratitude!

[@Medcram]

Victor Ruiz Thank you for the feedback

[@DMomsFan1]

My physiology professor sent me here, excellent video really solidified it for me!

[@Medcram]

+gymnastdancerstuff Good to hear- thank you

[@thetomatoczar7892]

That actually really helped me! I normally avoid watching these videos because I just can't pay attention, but I somehow managed to focus and understand it. :D I'm so happy right now.

[@confidencemthombeni9540]

Thank you sir you saved my life for the next physiology test

[@Medcram]

See the whole series at www.medcram.com along with other top quality videos including reviews in pulmonary, cardiology, infectious disease, and hematology!

[@ceciliawong9370]

o my! thank you. this makes so much sense than the text! i read the thing for like 20 times.. and everything got so much clearer after watching this.

[@brahmification]

Super Clear and Easy to follow and understand. Best to do background reading and all will understand that much better. THX!!

[@foxcatherine]

Wonderful. I am a Physiology Professor. Your video really helped me and my students better understand the mechanism of of -Hemoglobin dissociation curve. Thank you. In my opinion, visualization is a key component of the medical education.

[@Medcram]

Thank you- glad the video was helpful for your students

[@CindyCin1122]

This helped me visualize the curve much more clearly.

[@OMAROmar-gl9jt]

I have an exam tomorrow. thank you for making it easier.

[@Medcram]

OMAR R glad the video helped- thank you

[@shallknowitall]

Excellent walkthrough, just found you guys while studying for a Biochem final. Enjoying the videos.

[@Medcram]

+Scott Hall Good to hear. Best wishes on the final

[@vkgof]

Super straightforward and clearly explained! Thank you :)

[@onlyone4894]

how amazingly explained the confusing concept...thank you so much

[@hassanmehmood720]

Excellent...better explained then in first aid for usmle

[@andersmoberg867]

Well put; I finally got a grip, which is very nice, since I'm taking an exam in molecular cell biology on Saturday :)

[@kevinlomibao703]

Tomorrow's my exam, helped a lot. Thanks!

[@sakariyemustaphe3930]

thanks ,you just saved me so much time ,and my concept is very clear now ,i think its very helpful for every medical studen

[@anadimeska9464]

Very neat hand writing for a Dr, others should take note!

[@minimedlessons]

Great video! Explained so clearly. I LOVE MedCram content! I've been making similar videos, inspired by you guys. Keep up the great work, MedCram!

[@bethw8126]

Thanks! You just saved me so much time!

[@chandlerjacobs1714]

You are incredible. Thank you so much for making this topic so much clearer and simpler than how I was taught. Very appreciative

[@hanafakhoury8144]

Excellent explanation! I am going to share with my students!

[@javiendsnow]

Thank you very much for this video. My biochem book doesn't like to explain what cooperativity really is, nor does it explain the curve very well. Who knew it would only take 8 minutes to comprehend.

[@jenniferschori9144]

Great! This was a terrific refresher! It's been a long time since I learned this in vet school!! Funny how the importance of glycolysis/cell biology/biochemistry come back to haunt you - if only I'd realized way back then, perhaps I'd remember it better!

[@IsmaAragto]

Thanks a lot. I read the oxygen disassociation curve in the text book and it made little sense. Watching this video, I finally understand the relationships. Thanks a lot.

[@jacabuswalford4201]

Concise and clear. Thank you for your efforts.

[@allenc84]

Excellent! Love the high to low-level approach - very holistic. Thank you, Doctor.

[@Medcram]

Cory Allen Glad the video helped- thanks for the feedback

[@FrederickCFreddie]

My Respiratory Therapy Class from La Cité Collégiale would like to thank you greatly. Was wonderful for physiology class!

[@GG-yy4yx]

I'm taking my MCAT next week and this has been greatly appreciated. I loved the video.

[@Medcram]

Thanks for the feedback- best of luck on your exam

[@Celenecho1997]

Gerardo G lol i'm taking my IB exam in highschool and I need to know this too! Cool to think that we are studying the same concept!

[@missmorley8766]

Thankyou very much for this. I have really struggled to understand this concept but your video has helped. I have my exam in 2.5 hours so I just had one last look!

[@weaseloption]

Excellent concise explanation of this concept

[@adrenalinestat]

Easily and logically explained - very useful

[@Medcram]

Abhishek Mitra Thanks for the comment

[@madhusudantudu8748]

Wonderful presentation of the topics and beautifully explained like never before.......

[@genegonzaga7415]

@CmanCorportaions: yes. Thanks for the explanation of this. I've seen this numerous times before and have had to re-learn it repeatedly. This made it quite clear

[@toraNOchii]

This is really helping me out on studying for an upcoming exam. Thanks a lot!

[@pratikthakkar81]

Love the video, you have explained 4 big pages from my book in just few minutes, simply awesome! Really appreciate all your hard work. Thanks for helping.

[@aliciaduyvejonck4193]

Great lecture! I have always had trouble understanding oxygen-hgb dissociation curve! Thanks!

[@kittysexy2010]

Very good explanation it was really easy to understand your video!!! It helped me a lot! Next week I will have my exam! Thank you.

[@christopherhoward7353]

These videos are amazing. I am a paramedic with aspirations of going to medical school. Im learning a ton!!!! Can you please do a video on increased vascular permeability secondary to shock. I transport a lot of patients on levophed and other pressors. Id like some a more indepth look at the A&P of whats going on at the cellular level.

[@doctordoom02]

I think it's impossible to explain this more clearly! And I don't even speak English! THANK YOU!!

[@Medcram]

Good to hear! Thanks for the feedback

[@doctordoom02]

@@Medcram my pleasure!

[@tiakoyonga9152]

Awesome. It is much more clear in my mind now. I can actually explain it to someone else. Thank you

[@Medcram]

+Tiako Yonga Great to hear- thank you

[@TTerminatorr]

Really cleared up lots of concepts and the relationship.

[@Medcram]

TTerminatorr thanks for the comment- glad the video helped clear things up

[@littleeggy]

@megan moon. They said it was because by the time 3 oxygens have bound to Hb, it is more difficult for the fourth oxygen to bind because there is only one space left to fill. It's because the red blood cell has to bump around the right way to fill that last space with oxygen. So maybe the actual affinity for the fourth oxygen is higher still but it is harder to make it saturated because the red blood cell with the free space left for the fourth oxygen has to bump into an oxygen correctly for it to do bind and that is why the curve levels off?

[@TheMythogenic]

Perfect, now i am ready to my exam in med school

[@congratulation46]

A great video. Thanks a lot , this is the first time I really understood the curve.

[@Rorscharchblot]

Nicely explained with terrific diagramming.

[@Medcram]

Barbara Benson thanks for the feedback

[@NightshadeGengar]

Invaluable presentation! Thank you, easy to understand and hopefully I'll do well in my Biology finals.

[@SammiDaCosta]

Respiratory Student thanks you for a brief study recap!

[@Medcram]

+Samantha Da Costa Thank you for the comment

[@elizabethnovotny826]

I appreciate your lectures! They have been very good supplements to my schooling! You do an excellent job with them! Take care and God bless!

[@Medcram]

Elizabeth Novotny Good to hear- thank you for the feedback

[@dion8070]

Wow this was really well explained thankyou verymuch I took plenty of notes

[@stevekeres]

No, it's what he said too, from memory he just explained what you wrote in terms of affinity and cooperation (owtte)...it comes to the same thing, no need to be unsure!

[@depthperception8373]

Thank you so much! Clear and comprehensive.

[@edwincruz2617]

Very easy to understand.Nice review.

[@evelynbell6336]

Such an amazing explanation. Thank you so much sir

[@JacksonReynolds]

EXCELLENT recap.

[@BANAplus]

Wow, this makes so much sense now, thank you very much!

[@hyperkiz]

Thank you. That much clearer than from my lecture.

[@omfgmedic69]

Very clear, excellent refresher

[@pattyschaefer3584]

great lecture that really solidified some whys and wherefore for me. thanks!

[@user-ql3ge2us4s]

Thank you so much, this was exactly what I needed

[@musiconfire10]

Thank you soo much!! This was awesome!! I am studying for Boards and needed a quick refresher!! :)

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Thank you so much! These videos make everything much easier to understand!

[@Medcram]

+Brittaney Khong Thanks glad the videos have been helpful

[@user-nz4ux4cw2z]

Excellent. great job with this presentation.

[@daniellecatalanotto9128]

Thanks so much! Helped me understand it more clearly. I will be watching more of your videos!

[@jlcooper841]

Absolutely terrific explanation!!!

[@donatellofreak25]

Very helpful, explained clearly compared to the 4 paragraphs in my text book. Thanks!!