PARKINSON'S DISEASE

TALE 16 : PARKINSON'S DISEASE
VIDEO GUIDE
00:14
PARKINSONS’S DISEASE
 Definition
 Symptoms
00:40
Pathophysiology of Parkinson’s disease
 Involvement of Substantia nigra and Neostriatum
 Pseudoparkinsonism
03:25
Treatment strategy
 Correction of imbalance between Excitatory cholinergic neurons and Inhibitory dopaminergic neurons
04:20
Drugs used in the treatment of Parkinson’s disease
04:40
Levodopa + Carbidopa
 Mechanism of action
 Advantages of synergy
 Therapeutic uses
 PKs
 ADRs
 Interactions
11:55
MAO inhibitors
 Examples
 Mechanism of action
 Metabolism
 ADRs
13:26
COMT inhibitors
 Mechanism of action
 PKs
 ADRs
15:43
Dopamine receptor agonists
 Examples
 Mechanism of action
 ADRs
 PKs
19:25
Amantadine
 Mechanism of action
 ADRs
20:33
Antimuscarinic agents
 Role in Parkinson’s disease
 Examples
 Mechanism of action
 ADRs
21:36
Summary
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