Paxlovid - a new oral antiviral pill for treatment of COVID-19 by Pfizer. Nirmatrelvir & ritonavir.

This is a complete new drug review of Paxlovid, an oral antiviral agent used to treat COVID-19. A visual explanation of the drug’s mechanism of action as a protease inhibitor will be shown. The restrictions placed on this new drug due to its emergency use authorization will be outlined. Results of the EPIC-HR study will be discussed and evaluated to determine how effective Paxlovid is against Covid-19. Covered topics include contraindications, drug-drug interactions, precautions, and adverse drug reactions. This is a concise review that hopefully will provide the healthcare professional useful information.
Additional News and Links:
** July 6, 2022. FDA authorizes pharmacists to prescribe Paxlovid with certain limitations. www.fda.gov/news-events/press...
** June 16, 2022: Paxlovid not shown to be beneficial in relatively healthy low risk individuals. See LA Times article: www.latimes.com/science/story...
** May 6, 2022: Additional Paxlovid information: 1) Patient eligibility screening list (including drug drug interactions), 2) Paxlovid Locator Tool. www.fda.gov/drugs/news-events...
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Paxlovid official FDA News release Dec 22, 2021 www.fda.gov/news-events/press...
Fact sheet for Healthcare providers (contains drug interaction chart) www.fda.gov/media/155050/down...
Fact sheet for patients (English) www.fda.gov/media/155051/down...
Fact sheet for patients (Spanish) www.covid19oralrx-patient.com...
Pfizer Paxlovid website www.covid19oralrx-patient.com...
Paxlovid FDA FAQ Dec 22, 2021 www.fda.gov/media/155052/download

[@dotbirdbudgieshingleton-sm8693]

Just commented on a reply, this medication saved me from the hospital ventilator. Thanks for the video👍

[@elainehildebrand5886]

I was prescribed this about 3 weeks ago with excellent results except for very bitter after taste which didn’t go away until about 36 hours after last dose.

[@dotbirdbudgieshingleton-sm8693]

This medication has just saved my life. Yes the aftertaste was prevalent, but a small price to pay and kept me out of hospital.👍

[@dytrdr5]

@@dotbirdbudgieshingleton-sm8693 same here, I was fairly sick and probably would’ve gotten much worse if it wasn’t for this medication

[@RiDankulous]

@@dotbirdbudgieshingleton-sm8693 Glad you got well fast with the help of the medicine.

[@sweetcandy1005]

Thanks very much for the video. It is so rich of information and great choreography of slides, really enjoying it.

[@thepharmeztutor716]

I’m glad you enjoyed watching the video!

[@gmbowdle]

Can you do a video of Paxloid as a possible treatment for long covid?

[@angelfiyah]

I just started paxlovid 30 mins ago (evening dosage). I hope this helps me because my Covid-19 symptoms are horrendous. I will check back and let you guys know the effectiveness. Also, It was free through CVS pharmacy. Good luck to everyone! ❤

[@marialumena]

Hope you are feeling better.

[@veganath]

My unvaccinated at risk brother(obese) has started Paxlovid yesterday, and is concerned, are you able to give us an update of your outcome from using Paxlovid? Thank you

[@mahinahsan8363]

I started last night , done with second dose , lost my sense of smell and taste after the second dose - and feeling very depressed. Am on my third day of Covid + , fyi I have asthma too. Hope everyone feels better and stay safe

[@rv74b2002]

I started paxlovid on day three of symptoms. I noticed less inflammation in my sinus within an hour. All the body aches and chills were also gone. Giving me a chance to finally sleep. It did give me diarrhea. I ate Greek yogurt before the next any further doses and it helped. I’ve done four doses so far and feel much better. I do have drainage remaining but that’s manageable.

[@SarahBown-fo6fv]

How much does it cost for a full treatment?

[@susanaacostazimmermann9384]

I think the one on one therapy is less toxic and does cover more than 5 days. I extended to 7 or 8. With a negative test result. These are very potent antivirals. You may experience a little stomach upset. I think thumbs up. Vaccine therapy is good to look at.

[@edbyrnes]

Just took my first dose and have a 102 fever. Can I take advil with Paxlovid to deal with the fever and body aches?

[@RiDankulous]

It is my understanding that this drug has emergency use authorization in high risk groups for covid treatment.

[@thepharmeztutor716]

Hi Joe! Yes. Pfizer stopped their study looking at the use of Paxlovid in relatively healthy patients who are at low risk for hospitalization and death because the drug did not show any benefits in this group. Paxlovid is best to be used in high risk groups as you stated.

[@RiDankulous]

@@thepharmeztutor716 👍

[@blazeconnolly9960]

I got covid a few weeks ago And was given paxlovid, because I have stage one emphysema, I had covid for 8 days, then was completely better

[@LS-yf9qs]

This is my third day taking Paxlovid of my 5 day prescription..my first dose was evening..after some hours, i tasted bitter and it last for hours before i took the second dose the following morning..i hope it's just the bitter taste side effective and after 5 days, Covid19 will be gone ..

[@tatydial12]

Update? Did it help?

[@keithosullivan9174]

Life saver taste weird do

[@thepharmeztutor716]

Additional News and Links: ** July 6, 2022. FDA authorizes pharmacists to prescribe Paxlovid with certain limitations. www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-pharmacists-prescribe-paxlovid-certain-limitations? ** June 16, 2022: Paxlovid not shown to be beneficial in relatively healthy low risk individuals. See LA Times article: www.latimes.com/science/story/2022-06-16/pfizer-says-its-covid-pill-doesnt-work-for-healthier-patient

[@thepharmeztutor716]

Additional News and Links: ** May 6, 2022: Additional Paxlovid information: 1) Patient eligibility screening list (including drug drug interactions), 2) Paxlovid Locator Tool. www.fda.gov/drugs/news-events-human-drugs/fda-updates-paxlovid-health-care-providers?

[@marialumena]

Hope you are doing better. Prayers with you.

[@ruthcoffey3120]

One of the downsides is a sore tongue. I have had a sore tongue for 2 months. I would never take it again. Leave the experiments to mice, thank you.

[@montanagal6958]

Rebound Effect: when you stop the drug, Covid comes back worse, YEAH!

[@lipstickprincess1]

Folks are having issues with this drug. 🤷🏻‍♀️

[@pippilongstocking-qs7fm]

Like what kind of issues, please? I just took my 1st dose

[@thepharmeztutor716]

Additional News and Links: Paxlovid official FDA News release Dec 22, 2021 www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-authorizes-first-oral-antiviral-treatment-covid-19 Fact sheet for Healthcare providers (contains drug interaction chart) www.fda.gov/media/155050/download Fact sheet for patients (English) www.fda.gov/media/155051/download Fact sheet for patients (Spanish) www.covid19oralrx-patient.com/files/Patient-Fact-Sheet_Spanish_FDA-APPROVED_PAXLOVID-EUA-and-MATERIALS.pdf Pfizer Paxlovid website www.covid19oralrx-patient.com/?gclid=CjwKCAiA24SPBhB0EiwAjBgkhvxMWIXZk1FY-stLwBE4fQuRUItiP1hcuBUDZk9Eyvy8Fw67lNS-8RoCF9UQAvD_BwE&gclsrc=aw.ds Paxlovid FDA FAQ Dec 22, 2021 www.fda.gov/media/155052/download