Pedigree Analysis methods - dominant, recessive and x linked pedigree

Pedigree analysis by suman bhattacharjee - This lecture explains about the different rules of pedigree analysis. It explains how to find a pedigree based on characteristics with examples as dominant pedigree, recessive pedigree and x linked pedigree.
Dominant inheritance - affect shown in every generation
recessive inheritance - skips generation
X linked recessive trait - Male offspring are affected more.
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Thank you for watching

[@nabeelmusa722]

Attention please. Pedigree no 3 can be both x-linked recessive or autosomal recessive.. Very important to look again and again .. Both possibilities are applicable..

[@pranjalkumar7693]

Yes there is no any probability of x linked pass father to son but there is also a probability is that trait comes from mother...

[@KJKP]

At 15:55, Shomu says that, in X-linked recessive pedigrees, the trait NEVER transfers from father to son.

[@enoch9019]

Both can apply here

[@enoch9019]

@@KJKP but if both parents are affected, then the daughter is getting it from the affected father and the son is getting it from affected mother.

[@liteducks]

Because both father and mother are affected in the second generation, it is hard to discern whether the sons received the trait from mom or dad therefore allowing both autosomal recessive and x linked to be possible

[@roshansharma2309]

You are the first person who explain logic behind the topic

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@over-pronouncedmayonaise3464]

@@shomusbiologyofficial Yes!

[@elisabethnoe5952]

I see you have professionalized your introduction. LOVE IT! I have been watching your videos for some time and am impressed with the direct, concise and thorough approach you take in your presentations. Your hard work is greatly appreciated and well loved by many students. Come visit MacEwan University Edmonton Canada!

[@shomusbiologyofficial]

+Elisabeth noe thank you. It's a pleasure to help you out.

[@stavshmueli6932]

For the third question, from the diagram you can deduce that it's either x-linked recessive or autosomal recessive. It's unsure which one of the two is correct though, need more information. Additionally, for the fourth question, it doesn't have to be x-dominant, there're other inheritance patterns that fit that pattern...

[@Helloomi97]

i also got that and i was so confused when he said it couldn't be x-linked recessive..

[@bightonchinembiri]

two semester now gone, you have always been a life saver, keep up with the good work, brilliant videos there

[@zainabqureshi9178]

Hey

[@gajappriyavenkatachalam3197]

Thank you very much sir, the way you teach the concepts is amazing

[@sitthuson]

Practice pedigree #2 and #3, I see it as being "Autosomal R" & "X-linked recessive"... The rules about skipping generation and male to female ratio don't entirely eliminate x-linked. those rules are not always reliable. Care to explain?

[@cluelesshitchhiker1572]

Ig the #2 is X-Linked Recessive

[@Sona-yf4cl]

Thank you so much sirr😍😍 from the past 3 -4 days I'm trying to understand pedigree but now at the time only I can understand the concept clearly with some golden rules .Now I can gain some extra marks in exam 😉

[@shomusbiologyofficial]

You're welcome. Glad you liked it

[@user-ep6ir5rf5j]

Neet wale like button😂

[@sherylmateva8777]

😂😂😂

[@varunazoologylecturer6387]

its make me to teach others very easily.thank u sir.

[@ayishathulbareerasp4967]

Sir i have a question: what is the purpose behind checking whether an autosome linked disorder is dominant or recessive using pedigree analysis?Is the treatment of autosome linked dominant disorder and autosome linked recessive disorder different?

[@SB-wy2wx]

The autosomal recessive pedigree's third generation: "sweet home Alabama"

[@jaanvi6083]

😂 u both go to evry video and say the same🙄😵🧐

[@chelseaj5455]

lol I just noticed that

[@nandhiniv2218]

@@jaanvi6083 yah 😂😂

[@jaanvi6083]

@@nandhiniv2218 i literally find this wtevr video i see yaar😩😴😒

[@azeemsiddiqui3853]

lmao besttttt

[@ramymelhem]

in the last example, could u not also say that it could also be due to an autosomal recessive condition? i mapped it out and it seems to work.

[@Kaandhal-or3gu]

It can never be recessive cuz its seen in all generations

[@varunazoologylecturer6387]

sir thank u very much for giving important message.

[@KJKP]

Problem #4 can be autosomal dominant. I think Shomu’s “golden rules” might be more like strong suggestions with frequent exceptions.

[@backstreetfan2887]

I agree

[@ImALLENITE]

Yes the 1st option is the correct BCOZ we have to take the left side also in our analysis 👍

[@rasmiranjanbehera4118]

So simple concept...tysm sir 🙏🙏🙏🙏🙏

[@moniko7503]

Thank you! This helped so much!

[@07soumimondal91]

Guitar

[@sophiagarcia9018]

@@07soumimondal91 please what does that mean LMAO

[@almirapebryana2876]

thankyou so much. i have exam tommorow, after watch this video i understand this pedigree methods

[@shomusbiologyofficial]

Glad it helped. Please share and subscribe

[@SandeepKumar-nc9bm]

sir plz see again to question no 3 .It can also be x_linked recessive.

[@PrernaSharma-fb6pl]

Thank you so much! Ur videos are the best!

[@majidabdullah6598]

Sir with fue respect I want to know if the third problem solved is really autosomal recessive... Since in second generation the each of parents are coming from another family by considering that we can say that it's an x linked recessive trait. Correct me if I'm wrong. Thank you

[@skeletortheskeleton1357]

DUDE. IM CLOSE TO MIDTERMS AND THIS IS A LIFE SAVER. YOU ARE SO SMART. I LOVE YOU, THANK YOU!!!!!!!!!! KEEP IT UP!

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@mayukhroy5393]

-This video was very very helpful , Sir.

[@nnyadav5595]

hey in this video there is five female are affected,and only four males are affected.how can this problem is autosomal? there is no 50-50 chance of both male and female being affected

[@shailendersingh3293]

Yaa it's an nice outlook we can lay emphasis on x linked dominant if we see in the chart the ratio of transfer of disease from moter to son is more than father to daughter so it can be a x linked dominant

[@dkbhasinhealthcare]

It very important topic study with logic clearly explained . Great sir, please explain Disease HAE ( heardetry Angioedema )

[@AnuragSjngh]

Thanks for this video it's is very good

[@shreeshdas4507]

Thank you for uploading this video is very helpful

[@Anne0718]

great VIDEO. Thank u too much

[@amairaniramirez8855]

Live saver! Thank you!

[@shomusbiologyofficial]

You're welcome

[@Yournightmare_435]

This is so helpful. Can’t thank you enough ❤

[@shomusbiologyofficial]

You're welcome

[@snigdhaaachi6066]

Thank you! Helped a lot.

[@shomusbiologyofficial]

You're welcome

[@sehunnight4198]

i spent a day a understanding my professors lecture about pedigree bcoz its included in my exam and i cant really understand it. and i watched your tutorial for the last minute, saw your vid and glad that u explain it well. now i can answer my exam later confidently. thank u so much. keep up the good work sir and keep safe. more power 💪🙌

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@vaishnavijadhav101]

thank you for such a nice explanation

[@shomusbiologyofficial]

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[@sindhujavb8551]

Thank you Sir, for providing such a clear explanation.

[@shomusbiologyofficial]

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[@esnh6372]

Amazing video, thank you so much!!!!!!!!!

[@shomusbiologyofficial]

You're welcome

[@lukelingo9181]

i have a question for the fourth pedigree in the second generation dosen't the daugther also get affected even tho the father isn't dosen't that mean the daugther is affected from the mother but isn't that like impossible if it's meant to be x linnked

[@chetnamittal7126]

o have a confusion that how can a trait be autosomal if more no of female are suffering from a disease

[@ANGELAAR]

Beautiful presentation ..concepts very concise❤

[@shomusbiologyofficial]

You're welcome

[@bhatyasin2244]

Problem No. 3 follows x linked recessive inheritance...I have checked genotypically... Please remove the confusion

[@shubhamsinghbartwal2028]

In pedigree 3 in case of affected father do not pass traits to their son. But sons can be affected by affected female.. But affected sons can come from affected mother, and affected female can come from affected father... Why not x linked recessive or dominant...

[@sthelilesihle5102]

Sir, when looking at individual 7&8, could we say it's autosomal dominant because the trait didn't skip the generation?

[@mr.abundant6449]

Thank you shomu bhai....

[@pholososhamukuni9971]

THANK YOU SO MUCH...REVISING AND GOING WELL❤

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@themadladprince430]

15:05, I don't understand why it would be a form of dominance. If both the parents were reccessive, then by crossing rr x rr, all the progeny are affected. Can someone please explain to me why it is a form of dominance?

[@IM-bc3tm]

Vary helpful thank you(:

[@shomusbiologyofficial]

You're welcome

[@YouTubesucksman]

Atlast got an explanation in English

[@Astralarius_Zenith]

Thank you for this video! When we talked about this in class I was confused. Now I am having more clarity to the topic thanks to your video.

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@avneetkamboj6219]

Very helpful video for understanding pedigrees

[@shomusbiologyofficial]

You're welcome

[@theorange8755]

Wonderful thank you

[@shomusbiologyofficial]

You're welcome

[@nouraalmousa4958]

Salam , how are you ? ….. may I ask you please the Fragile X syndrome fall under which Inheritance PatternX-linked Recessive or Dominant (or both)?

[@zainabqureshi9178]

Walekumsalam

[@lewisbeard8105]

Number 2 looks more like a case of Autosomal Dominant with reduced penetrance?

[@chepkorirvicky7558]

You the best, I had to subscribe❤

[@shomusbiologyofficial]

Thank you. Glad you liked my lectures

[@anilkumarsharmazoology8333]

Thank you so much

[@shomusbiologyofficial]

You're welcome

[@mahaavtarbabajineebkarolibaba]

exellent explaination... wow amazing

[@shomusbiologyofficial]

Thank you

[@hridaybaruah]

I THINK THE PEDIGREE AT 14:22 CAN ALSO BE EXPLAINED BY X-LINKED RECESSIVE DISEASE. WORKING OUT THE GENOTYPES MAKES IT LOOK LIKE A COMPLETELY PLAUSIBLE ANSWER. PLEASE DO CONSIDER IT ONCE AND I MAY BE WRONG BUT COULD YOU PLEASE EXPLAIN, ITS REALLY CONFUSING ME

[@daxaprajapati6581]

Thank u so much

[@rosaundra_eugenia]

In pedigree example 2 there are 5 females affected and 4 males affected, or am I wrong? Secondly, In pedigree number 3, couldn’t it be distinguished as autosomal recessive because 2 unaffected parents have an unaffected child on the left side and also because 2 parents have all affected children on the right side? Why is the right part where 2 affected parents have all affected parents identified as autosomal dominant?

[@gamingid648]

Very helpful keep going on bro❤️🙏❤️

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@shikhadwivedidwivedi9869]

Please sir clear a doubt in A-R if assume three offspring then is it possible one offspring disease affected and other two not

[@moelol7113]

Hello from 2021, 18:04 sir this pedigree can work as sex-linked recessive

[@emmanuelchipeta1622]

It really has helped 💓 thank you

[@shomusbiologyofficial]

You're welcome

[@tinkeshpatidar3881]

Sir last wale quastion me outsider ko Carrer assume karna pad raha h......jo galat h.... Outsider ko humesha healdy male he manna padaga..... So x link ressesive padigree hogi last wale quastion me

[@zooharafique1826]

ThankYou! For this helping video ❤i didn't understand ever about these conditions of pedigree, but i must say after i saw this i can easily solve my all questions related to these four traits... 🌸🌸✨✨✨

[@prateeksingh9483]

Still confused

[@shomusbiologyofficial]

You're welcome

[@harrystylesmiddlefinger]

@@shomusbiologyofficial wait wtf lol

[@thisumamarasinghe8171]

😢

[@user-ll6td7nl3f]

i love you. you saved my midterm exam :)

[@shomusbiologyofficial]

Thank you

[@gautomibasumatary5478]

Thank you sir.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@sangyunlee9243]

Can problem 3 be xlinked recessive? because Gen 2-4 female is a career XA Xa.

[@sahildhull2662]

thankyou very very very much...... sved my genetics exam.......

[@shomusbiologyofficial]

+Sahil Dhull thank you

[@jishavinukumar1412]

Thank you sir for taking the class in English

[@shomusbiologyofficial]

You're welcome

[@indhuunni5181]

Is congenital defness of 2 son from normal parents a AR inheritance

[@jenvipatel5541]

Thank you! This video helped me understand the 4 different types of pedigrees for my biology exam!

[@shomusbiologyofficial]

You're welcome

[@GunjanR516]

Janvi Or jenvi?

[@asuramunikavishadesilva371]

thank you so much sir!❤

[@shomusbiologyofficial]

Most welcome!

[@Aesthetic_fact69]

Thank you so much sir 😊...... You explained it very well... But I didn't understand last two pedigree charts According to me i think 2nd last is X-linked ressesive And the last one

[@sahilrampal5723]

Very helpful

[@shomusbiologyofficial]

Thank you

[@aboutstudies123]

Explanation is good Sir. Thank you. A small query Sir, "Among 1,5 and 7 Criss-Cross inheritance is observed. At 4 and 9 also depicting criss-cross inheritance. Why can't it be X-linked Sir? Please clarify

[@aboutstudies123]

Regarding case 3

[@katsanlavers]

Вау, это очень круто! Спасибо

[@badtameezdil3119]

Helpful

[@sohailshaikh6735]

Thank You Sir

[@shomusbiologyofficial]

You're welcome

[@taqwaejaz980]

Thanku Sooo much sir

[@shomusbiologyofficial]

You're welcome

[@mersijaalic3045]

You have explained it well, but i think that you should have written genotypes for each person. In that way we could see if we did the excercises well (3. and.4. exp). :)

[@manojmanly1057]

Nice explanation

[@rscreativevideo5417]

Shomu sir today I have answered all question except one from pedigree .It is all because of you.U r really god of biology.No words to say about u.soulful thanks from tamilnadu

[@theamariecabaccan]

THANK YOU SM AAA

[@shomusbiologyofficial]

You're welcome

[@ranjani4899]

simply nice and understandable..

[@shomusbiologyofficial]

+Prathisha Ranjani thank you. Glad you liked my lectures

[@sathyavathimurugesan7099]

Sir but in 3rd example the mother were affected father was not then how in 2 nd generation she will be a carrier

[@12hmbkjayant72]

TOTAL BANGER EXPLANATION

[@shomusbiologyofficial]

Thank you

[@hurmacala]

In example 3, why is it not X-linked recessive, ok, the father does not pass the disease/trait to the son, but is the mother also affected?

[@joseluisboffillborroto5407]

Podría usted hacer la traducción de ese análisis del pedigree en idioma español?

[@FlatDrifting265]

this was taught better than my teacher. thank you.

[@shomusbiologyofficial]

You're welcome

[@philippeter198]

very helpful

[@user-ow9oz4pp4i]

Your voice is soo sweet pleasant to hear bro🤘❤️

[@shomusbiologyofficial]

Thank you

[@joankemboi2261]

Thank you😇😇✨✨

[@shomusbiologyofficial]

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[@allrounderteck5011]

Thank u brother

[@shomusbiologyofficial]

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[@nicoleviloria5184]

This is the first time I get it!!

[@user-og8pl5tk1i]

2023 and this video is helping me. Shout out to You

[@shomusbiologyofficial]

Thank you

[@ontheway9311]

THANK YOU SIR

[@shomusbiologyofficial]

You're welcome

[@muktapal6240]

Thank u sir

[@shomusbiologyofficial]

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[@shkaif2531]

In last question disease is transferred from mother to daughter so how it be a X linked disease

[@shafiahmadtalukder3543]

no 3 is confusing sir,please recheck this

[@chandanbiozone5456]

plz rechecked ur 3no. q I think it's x linked recessive

[@_becca_beeboo]

Really? Because I got X-linked Dominant.... Now I'm really confused ://

[@ricksarkar6680]

@@_becca_beeboo 3 and 4 don't show the trait, but one of the offspring do, therefore the mother has to be a carrier (heterozygous) and one can only be heterozygous and not show the trait if the trait is recessive

[@_becca_beeboo]

Rick Sarkar oh, okay. Thank you! :)

[@stavshmueli6932]

It can either be x linked recessive or autosomal recessive. You can't really deduce which one from this diagram alone.