Pharmacology - DRUG INTERACTIONS (MADE EASY)

[@NatureRelax13]

My man is here 🫀😘 I watched every video of yours...like 5 times and guess what i passed my 3rd year pharmacology mbbs exam 😘

[@SpeedPharmacology]

Glad I could help!

[@NatureRelax13]

@@SpeedPharmacology 🫀🫀

[@woloabel]

@@SpeedPharmacology ya van a jotear.....gut es ist! Heil!

[@product_of_grace24]

the gift that keeps on giving!!!Bless you guys!!

[@c0r5e]

Hey man! Can u do a video on cns stimulant medications? Love ur content

[@Madridista7-98]

Sir thank you so much 🙏❤️

[@nakibomar8275]

Oh man! The legend is back!

[@fatmaelsayed8933]

so informative

[@HafizMuhammadIdreesHabib-oj8iv]

Very informative & easy to learn

[@zanyarkurdi6711]

Thank you from kurdistan ❤

[@marc5206]

Thank you!

[@Julianwithbenefit]

Sir can u guide me plz which software you used to make such videos?

[@miguelalonsogarcia2475]

Great work

[@TheSamuill]

I swear these videos are quite helpfull on the road to my graduation. Keep up the good work man. Can you make a video about Osteo-related drugs or illneses ?

[@SpeedPharmacology]

Working on it ;)

[@syedwaqasshah5744]

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[@marcusaurelius841]

When are you making another video?

[@aftabpatente5287]

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[@clairethecraycraybutisstil2426]

thank youu!!! 😇😇😭😭😭🙏🙏🙏🙏

[@abhishekshakya6072]

Question: If Km=1/2Vmax, then CLint = Vmax/Km = 2(constant)? Please correct me if I am wrong

[@SpeedPharmacology]

Not entirely accurate. More precisely CLint = Vmax/(Km+[S]) but because in most clinical situations, liver enzymes are rarely saturated so [S]

[@abhishekshakya6072]

Question: What is the difference between perpetrator drug and victim drug? My understanding: Perpetrator drug is given later than victim drug as it stops or disrupts functioning of victim drug. Is my understanding correct? Is perpetrator drug already present in body naturally?

[@abhishekshakya6072]

As per pubmed, the dissociation constant(pKa1) for Duloxetine(perpetrator)=9.70 and Theophyline(victim)=8.81. Is Km similar to pKa1?

[@SpeedPharmacology]

In the context of drug interactions, a perpetrator drug is a drug that causes changes in the pharmacokinetics or pharmacodynamics of another drug, leading to an altered or unexpected response. This can happen through various mechanisms such as inhibiting or inducing enzymes involved in the metabolism of another drug, or binding to the same receptors as another drug. These changes can lead to increased or decreased blood levels of the victim drug, and alter its efficacy or safety. For example, a perpetrator drug may inhibit the enzyme that metabolizes a victim drug, leading to increased blood levels of the victim drug and an increased risk of side effects. On the other hand, a victim drug is affected by these changes in pharmacokinetics or pharmacodynamics caused by a perpetrator drug, leading to an altered or unexpected response. This can include changes in blood levels, efficacy, or side effects of the victim drug.

[@SpeedPharmacology]

@@abhishekshakya6072 Km is a measure of the affinity of an enzyme for its substrate, while pKa is a measure of the acidity or basicity of a compound

[@aminebachi947]

Legend

[@Bisbsnt]

need migraine phamacology

[@SpeedPharmacology]

Definitely 🙂

[@ayyanaaabid6345]

i didn't understand a thing :( I gotta watch it later...

[@MediTenPharmacy]

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