Prevent Aging within 20 Years? - Altos Labs' Cellular Reprogramming Excitement

[@LongevityScienceNews]

Do you believe that the 20 year timeframe is realistic?

[@nozhki-busha]

Absolutely, yes. I have repeatedly suggested this timeframe based on interviewing dozens of experts in the field working on OSKM reprogramming.

[@ct5471]

Well, Aubrey de Grey now thinks there is a 50 percent chance of reaching longevity escape velocity by 3036. So this is conservative by comparison.

[@grinmanpotato]

to be honest i don’t know. i would love to believe that - but some people say that’s far off i.e. Sinclair there are plenty of differing opinions and I don’t want anyone to fall victim to overhype. however, the shorter the time frame, the less deaths that will happen

[@fatboydim.7037]

I think it will sooner in the 2030s they haven't taken on board the arrival of more powerful AI units. Plus Dr Sinclair stated himself that things are moving at a much more rapid rate then even he predicted.

[@oricardoleal]

Absolutely

[@ss3mania28]

We need this sooner!!

[@nickjunes]

Once we can prevent aging we can truly start exploring the Universe and covering these immense distances properly.

[@joebidenw4385]

Exactly

[@KeepOnThinking]

Great to see our clip of our episode on Cellular Reprogramming in this! We have more on that on our channel if anyone is intersted.

[@xalspaero]

Aging is ultimately the worst disease of them all because it is 100% fatal. I'm glad this is being taken more seriously lately.

[@debasishborthakur2141]

You are absolutely correct brother..👍

[@edward3190]

imagine a 1 billion years old Jeff Bezos XD. or people need buy life span by money

[@justwannabehappy6735]

@@edward3190 so what ?

[@oluwapelumiadekunmi210]

I am happy that a time would come that terminal diseases will be easily treated but I have a very big problem with immortality

[@xalspaero]

@@oluwapelumiadekunmi210 immortality will never be a thing. you are still susceptible to traumatic injury, accident, murder, etc in a world where all aging damage can be reversed. "indefinite lifespan" is more accurate. but yea, you can either take the treatments, or not, up to you. important thing is choice.

[@ct5471]

Good to see that the number of high profile researchers in gerontology making bolder predictions about rejuvenation is increasing. This will make it easier for other researchers to follow. Also the public will become increasingly aware that this may be feasible, which in return will lead to more resources being allocated to the field. Great news

[@colourfulcrafts5492]

Totally agree mate 🙂

[@youdontknowme3935]

let's hope

[@jimj2683]

People have been just as optimistic about fusion energy for the last 60 years. Yet still zero results. Reversing biological aging is at least 100x harder than fusion energy. So I would not keep my hopes too high.

[@rgonzalo511]

​@@jimj2683 We have already reverse the age of mice plenty of times. How is it comparable?

[@jimj2683]

@@rgonzalo511 lol. 99% of treatments that work on mice never end up working on humans. I have been reading about amazing results for all kinds of treatments on mice for decades. Yet they never work on humans.

[@Red-drick]

Most exciting area of research currently happening

[@psylinx]

My name is George Davis about well just over 2 years ago I had a stroke. It definitely sent me back a bit but I've recovered most of who I. Am what I'm wanting is to make it at least until I'm 70 because I want this treatment and I'm hoping that it really comes about before I'm gone.

[@문현우-s8c]

Probably not gonna be available in 20 years, but we will definitely see some groundbreaking discoveries and promising results in that time frame with the amount of money they throw at it.

[@rgonzalo511]

Why won't it be available in 20 years? What makes you be so skeptical. I'm really a layman so this shit is so confusing.

[@squamish4244]

@@nl5076 The trials will take 10-15 years in the USA. In Mexico or Brazil...he he. Or not. We came up with a potential cancer drug using AlphaFold 2 in 30 days this year. Obviously they won't wait 10 years to use that. If they come up with a longevity drug in 30 days in five years, they will see results in months. So these days, with where AI is going, it could take a lot less than 10 years to start seeing results.

[@reshadunchained5113]

Researching aging for a video I’m making, and it’s encouraging to see tech disrupting long-held limitations! Reprogramming cells to hack youth is closer than ever.

[@BrentNally]

So exciting! Great job Ryan and the rest of the LSN team!

[@robd1859]

I want to live forever. Let's pray they make this happen. 🤣👍

[@12b-h5y]

20 years is a long time. I hope they can make it earlier

[@globaljobs1855]

Ye,we won t even be around anymore

[@mirandapillsbury7885]

sadly I don't see this happening until like 2080 and beyond. We will all be gone by then. Only people born in like 2030 and beyond will be able to enjoy this. Oh well

[@andreeanovac1328]

Some scientists say it will happen earlier within 10 years Or 5years they will come up with a breakthrough or a lonevity drug. Human trials could bein in short time. I m ready to go gor human trials 😂can t wait more

[@jacobbosse4507]

@@mirandapillsbury7885you from the future or sum

[@samuelyuri645]

Yes, keep up the good work!

[@barzinlotfabadi]

Wish we could have it in five.

[@LifespanIO]

These may seem like bold predictions, but they aren't far off from what other experts are saying as well.

[@WickedHole]

I know that David Sinclair and Aubrey de Grey are also predicting success in under 20 years.

[@ilyab.5127]

Mice longevity experts

[@UHFStation1]

I hope well under 20 years. After age 55 our DNA starts breaking faster. I need to be saved while there's enough left to be saved.

[@justwannabehappy6735]

@@UHFStation1 fasting, exercice and diet. There are mundane ways to prolong youth.

[@kerrspace5435]

@@UHFStation1 You can practice all existing longevity method like fasting, rapamycin etc and all these methods will buy you some more time.

[@PathWars]

Why did they state they aren't a longevity company? That part confused me.

[@LongevityScienceNews]

We posted a video on January 23rd that explores this further, but essentially Altos Labs’ founder & chief scientist Rick Klausner is quoted as saying “We do not view this as either an aging company or a longevity company, and I really feel strongly about that. And I think the science that’s going to emerge shows that yes, you can make cells that get dysfunctional over time healthier and more resilient, but it’s independent of age.” The news team at Lifespan.io reached out to Altos Labs to find out more, and they received a response saying “Altos is not an anti-aging or longevity company.”

[@rgonzalo511]

​@@LongevityScienceNews So I won't become young then?😢

[@squamish4244]

@@rgonzalo511 They don't want to freak people out. 'Healthy lifespans' sounds a lot less controversial. But make no mistake, they are going for longevity.

[@templeray5692]

I'll be 57 by 2042 so I guess I have a really good shot of seeing aging being cured in my lifetime I'll be able to afford the trements also so money won't be a issue by then.

[@squamish4244]

I'll be 63, so...fingers crossed for both of us!

[@jeremywvarietyofviewpoints3104]

I remember when gene therapy and stem cell therapies were going to cure major diseases in 10-15 years in about 2001.

[@squamish4244]

Yeah. But they didn't have anything like today's computing power or software, and they didn't have the $$$. They also messed up on a guy who died during gene therapy in 1999, which was done by very irresponsible people and set back the field. This is very different.

[@jeremywvarietyofviewpoints3104]

@@squamish4244 that would be good.

[@youdontknowme3935]

I always have a hard time being optimistic about news like this let's hope its not a sham

[@ericv9610]

Wish that could happen, even sooner. I lost all granfparents at young age. My parents and I are standing in the frontier of mortality. I dont want to lose my parents, or myself, to that eternal nothingness.

[@Danath1982]

"I don't care if you call yourselves a tire shop." :D Well said, I hope these predictions are right and I'm really hyped to see this kind of research start to get the funding it needs!

[@Azmarith]

To be fair, it would be a bit confusing if they called themselves a tyre shop.

[@alexandraspring687]

I suppose if you REALLY wanted to avoid the death lovers XD (or needed to ... O_O)

[@kwitseo]

I hope it would be in 10 years rather than 20. The sooner the better.

[@Rickalicious]

Bill gates infamously said we overestimate the changes that will occur in 1 or 2 years and underestimate the changes that will occur in a decade. Let's hope he's right. What a world with cellular reprogramming will look like? And just how long will we be able to live? Gets me excited for the future!

[@rgonzalo511]

It might come quicker David Sinclair and Michael Levin have been having several discussions about aging. Now it looks like 20 years might be a tad pessimistic.

[@noahlovotti7722]

​@@rgonzalo511be careful with stuff from david sinclair

[@danilogardes2781]

In 2042 I will be 72. Just in time to treat this deaded desease of aging.

[@globaljobs1855]

72 will be way too late for you

[@trumpisaconfirmedcuck5840]

@@globaljobs1855 Lots of people live into their 80s and 90s, so I believe OP can make it.

[@globaljobs1855]

@@trumpisaconfirmedcuck5840 they do but they are already decrepit i their 80 s

[@themechanictangerine]

I'll be 72 as well.

[@eyesofibad2461]

Hope you can make it man! Stay alert for the therapies becoming available.

[@beastboy3871]

About freaking time!

[@SilverFan21k]

More videos like this

[@kirastormy7222]

I think it would be correct to say that we are not primarily destined for immortality, but in our project, lengthening life will be inevitable. Since it is curious that they say we do not focus on immortality, however, what they are achieving is apart from reversing and rejuvenating cellulcas, it is that mice live longer and that in humans in different doses over time can give a much longer life long and better

[@kirillkulygin8799]

I think they are saying that they are not trying to achieve immortality because the death lovers are still there

[@justwannabehappy6735]

@@kirillkulygin8799 my exact thought !

[@SilverFan21k]

Very cool and optimistic! ❤

[@ramakrishna5480]

20 years is too long man

[@raunaklanjewar677]

How old are you?

[@ramakrishna5480]

@@raunaklanjewar677 the problem is not how old am I , will the scientist who working on it will live another 20 ?, And I'm 20 , my grandpa's 92 I'm worried about him

[@BavarianHobbit]

@@ramakrishna5480 We all have to die one day.

[@ramakrishna5480]

@@BavarianHobbit ur watching the wrong channel man

[@BavarianHobbit]

@@ramakrishna5480 I just got this recommended, I don't really care about this. I die when I die.

[@SigFigNewton]

Fusion power plants by 1990?

[@boulilanourelhak9638]

Nice work

[@Khannea]

It's the year 2148 and the robustly uplifted surviving family members of the mice that WEREN'T treated with life extension sue the scientists doing this research for letting their parents and grandparents die in comparative study trials.

[@henkjaegerde7591]

How big are the mice?

[@ET-oq9mg]

Nice video

[@Dan-uf2vh]

Once the ball is rolling, more and more interest / personnel and investments with appropriate infrastructure will grow exponentially. Thanks, Bezos! This move has drawn 10 or maybe even 20 years off from what could have been a 40 year long wait. Ultimately, getting the cells to rejuvinate is only the most base, crudest, way of doing it. If it were necessary, eventually the process could be coordinated with more artificial means (tiny robots, both electronic and biological) to transform the body into a picture-perfect version of a 20 year old. Obviously this is much more difficult, the point being that it isn't physically impossible.

[@kirastormy7222]

one question rayn,From what I have seen in your first bulletin and in the last update that you have done in those experiments, if you are working on rejuvenation and not so much on diseases, although with rejuvenation, after all, they manage to avoid many diseases. but it is as you say to me you can tell me that you are a wheel repair company but the results are that you fix the whole car well perfect After all, what shows what you are is not what you say but what you do. Therefore, do you think that they really do not say what they are for an ethical or moral issue and that many would oppose, including brands?

[@trumpisaconfirmedcuck5840]

I think it's largely for political and marketing reasons. Aubrey de Grey talks about rejuvenation avoiding an unhealthy state and that "longevity is just a side effect" because when he said stuff like "people would live 1000 years" everyone lost their crap! It "upsets the apple cart" too much to say "yeah, you're going to live in the body of a 25 year old for hundreds or maybe even thousands of years until you get hit by a bus." People are ok with curing grandma's heart disease or grandpa's Alzheimer's. They think that will happen through geriatric medicine (it won't or even if it does, end up futile and just buying a year or two until a stroke or something else gets them). Curing those diseases is "part of the plan" just like curing infant mortality is/was "part of the plan" and curing infectious diseases like COVID is/was "part of the plan" Living hundreds of years though? Not "part of the plan" which causes people to justify not doing it. "Hey I settled on the fact that I'll live to about 80, if I get another 10 or 15 years in decent health that's cool... but you're telling me now I shouldn't plan to die by 95 but maybe by 1095? LOL get out of here, that makes no sense! Tell me I have a decent shot of making it to 100 in good health first!"

[@Keenan686]

oh man tis reminds me of the movie in time

[@UHFStation1]

20 years is a very long time for any prediction. I could easily be dead in 20 years or at least have too little left of myself to salvage.

[@robd1859]

. Let's make it happen I want to go back to 20 years old and live for the next five thousand years. Or never die.

[@andrewhobbs5268]

to long for me to do what i need to do

[@sciencerscientifico310]

50% increase in lifespan? That means the average life expectancy could go up to 120 or 130 years old! Of course, if this is true, that also better be at least a 60% increase in healthspan. Spending one's last decades immured in a nursing home in kilotons of pain and so frail even the most basic of daily activities is impossible without assistance is hardly anyone's idea of a good time!

[@trumpisaconfirmedcuck5840]

There's zero reason to assume an increase in lifespan like that wouldn't include an increase in health span. Old people die because they're vulnerable to more than one disease/issue. Keeping them alive through geriatrics has a piss poor track record.

[@noahlovotti7722]

Increase in lifespan will prevent the aging related illnesses.

[@WackyGameEngineer]

Crazy, i really hope this works :)

[@squamish4244]

And these predictions were made before the explosion in AI in the last year. At least publicly available AI, like programs way beyond AlphaFold (60 to one million times faster) that labs like Altos can use. I'll be 64 in 20 years. I hope this works!

[@crafter2u]

i will most likely be dead in 20 years

[@thor4038]

yep ied bet on that

[@blackstratmx]

@@thor4038 wtf man 🙄

[@globaljobs1855]

You are just someone ordinary.no loss

[@rgonzalo511]

That sucks bro. Praying for you to make it till this tech is available 🙏🏿

[@globaljobs1855]

@@rgonzalo511 It will not be available in this lifetime, not in the next 50 hrs anyway

[@Galaxia53]

Your videos are good but it looks like you're looking through me as opposed to at me

[@sbcinema]

it's about time we finally stopped aging, i'm tired of having to change my girlfriends every couple of years... but joking aside, it's really about time (especially with regard to the settlement of other planetes, wich reqires long space trevle )

[@mckitty4907]

gross joke...

[@sbcinema]

@@mckitty4907 🙂

[@flashgordon6510]

Faster, please.

[@lilchef2930]

I’ll b 35

[@vasilismoutzouridis8080]

cool :)

[@mirandapillsbury7885]

the timeframe is impossible. I suspect we will get to a point where at least visually we can reverse or slow down aging dramatically (so more collagen in the skin for way more years...40 year olds looking 20 etc...) but everyone alive right now will be gone by then lol. I envy the ppl who will be born in the year 2080 and beyond lol

[@MarkusWaas]

with our current technology and knowledge you can already make it to 120 years if you’re born today and there would be zero new scientific breakthroughs. but obviously in those 120 years we will likely have many breakthroughs that could extend your life during that time. so who knows, maybe if you’re 40 years old and already doing everything to extend health and lifespan, you may make it to LEV (longevity escape velocity)

[@juanmf]

Experts became scammers lately.

[@nozhki-busha]

What all the experts? lol

[@juanmf]

@@nozhki-busha did I say “all”? Are all experts making bold statements like this? Yamanaka factors is discussed in David Sinclair’s book. He’s now under scrutiny for fraud. Sold a $700M startup based on Resveratrol and is effect on longevity. His studies are not replicable. Upsy.

[@robertlussier2944]

Just what's needed🙄 The rich holding on to their wealth for longer. The Earth can't support the billions already here.

[@justwannabehappy6735]

Earth can support the people. It's the fossil fuel industry that is the problem.

[@bluelunarmonkeytarot8533]

This is demonic as sh*t

[@LongevityScienceNews]

What is?

[@Dana_inc]

Aging is a disease! How is it demonic? Aging brings disease .

[@bradhilton2283]

No he has a good point , aging in a longer much heatheir form , than living for a long time in poor heath such a lot of our grandparents did . Aging with a better quality of life and for a much longer time , Seams much better than being an immortal invalent in a nursing home in chronic pain . So there is a difference . Imagine living forever , but getting sick all the time because you immune system is gone .