Smallpox (Variola Virus)

[@dailydoseofmedicinee]

Smallpox is thought to date back to the Egyptian Empire around the 3rd century BCE (Before Common Era), based on a smallpox-like rash found on three mummies.👍

[@Potatotenkopf]

Those mummies boutta make me act up

[@charlesg7926]

Sounds like Moses’ plague was a real thing

[@r.i.pyoutube6881]

@@charlesg7926 plagues have been around since the beginning

[@joanhuffman2166]

​@r.i.pyoutube6881 Even old diseases had a beginning

[@unknownbeing8222]

Proffessor dave is always here educating us, much love!

[@asusgaming4386]

for the love of god please keep making these videos

[@johndemeritt3460]

Hey, Dave! You mentioned four variations on smallpox, but only talked about one. When are you gonna cover the other three?

[@joanhuffman2166]

3:15 I have heard that smallpox was once responsible for 1/3 of the blindness found in Europe.

[@4dragons632]

A much needed story, proving what science can do for our lives.

[@Dragon-Slay3r]

It's remarkable that I got the cowpox virus 6 at work Xfiles s4 ep1

[@pedrovicnt_]

Literally the best intro ever

[@ahmadhourani3014]

you are better than all my professors

[@soilaverdad8446]

Very educative video however polio hasn't been eradicated in 3rd world like Mexico. In the remote rural areas of South Mexico polio is present and affects not only children but adults causing paralysis and the almost total destruction of limps.

[@Saifyrooma2nd]

this video is about smallpox though, not polio, though you're right. in my country of pakistan, we're also one of the last remaining areas on earth to have polio surviving

[@MushuaThePotato]

@@Saifyrooma2ndit haven’t been eradicated anywhere thanks to antivaxers who pose risk of spreading it due to stupidity.

[@timothyfoster5927]

I got vaccinated for small pox when I was in the Navy. Even just the open sore from the vaccine was gnarly. I can't even imagine what actually contracting it would be like.

[@jakejohnson6954]

Imagine yourself getting smallpox. Thats what it feels like

[@rodsurly8103]

Another great informative video. Thanks, Professor Dave!

[@quantumskittles]

Thanks for this information! May I ask when was it announced eradicated from Africa or South America was it also 1980?

[@petrfedor1851]

In Czech language smallpox and chickenpox share name neštovice with chickenpox being usualy reffered as false one.

[@yuriiitheenthusiast.]

Is smallpox literally more dangerous than monkeypox?

[@hrishirajchkrabarty4428]

Yes much much more dangerous

[@hrishirajchkrabarty4428]

Monkeypox is more dangerous than covid but is not serious,smallpox has severe symptoms

[@theredbanana5006]

Welp 2 years later we’re dealing with mpox 🙃

[@yuriiitheenthusiast.]

@@theredbanana5006 dawg thanks for reminding me of this comment 😭

[@STELLAR_PRIME]

The smallpox shots stopped in the 70s because it was eradicated, is that possible with coronavirus now? Or will it always be here, just as a flu in the future.

[@d0giem]

smallpox still exists in a lab, and that might be an important vaccine to maybe get a hold off. covid you can't stop with vaccination its mutates through it too well

[@Pre-Cracked-Egg1]

It is not possible to eradicate the coronavirus with current medicine since it's a zoonotic virus meaning it jumps from animal to human and vice versa.

[@alluyasismedicallectures5458]

Excellent explanation 👍

[@Joshua-kn6dq]

do you have a video on Surds by any chance? havent been able to grasp it very well.

[@saintjimmy2244]

Wasn't from the steppies near the black sea 16,000 years ago. They found pox mark on die burried in cave there.

[@Dragon-Slay3r]

🙀🌹💪

[@kevinc9447]

Sir, do you plan to do more videos on Humanities like Philosophy?

[@ProfessorDaveExplains]

yes definitely at some point!

[@Planarwalk]

It disappoints me that there are so many people that deny the efficacy of vaccines, which is the reason why some diseases that were almost eradicated are coming back. Also, I never noticed your tattoo before Dave, what is it of?

[@ProfessorDaveExplains]

check out "ask professor dave #3" where i talk about it!

[@Planarwalk]

@@ProfessorDaveExplains cheers :)

[@glennpearson9348]

Excellent explanation, Professor Dave. Is there any relationship between this Variola virus and the Varicella Zoster virus (chickenpox)?

[@tlw4237]

Not much of a relationship other than they both produce characteristic “pocks”, but are pretty straightforward to tell apart. Smallpox is sufficiently close to another viral disease called cowpox for cowpox to be usable as a sort of vaccine against smallpox, as was pioneered by Englishman Edward Jenner around the beginning of the 19th century. Cowpox, as it’s name suggests, is a bovine disease that can also be caught by humans and was associated with people such as dairymaids who milked or touched the udders of infected cows.

[@glennpearson9348]

@@tlw4237 Thanks! A curious explanation.

[@tlw4237]

@@glennpearson9348 I should perhaps have added that an easy way to tell smallpox from chickenpox is that if they’re left to their own devices and not treated chickenpox can be a bit disfiguring and leave small scars it’s very rarely fatal. Although if caught as an adult chickenpox, in the form also known as “shingles”, can be very unpleasant.

[@jamestoliman9081]

Varicella zoster is a type of herpes virus. It's completely unrelated to smallpox.

[@glennpearson9348]

Indeed. Since making this comment, I realize that the only things smallpox and chickenpox have in common are that they present as "pox."

[@iftekharhayat6171]

Thanks sir....Now I am suffering from this deasese,,,,Love You From Bangladesh 🇧🇩

[@WHATTHEFUCKISAKILOMETERR]

Smallpox has been completely eradicated from the earth

[@codk1nghi689]

Great video!!

[@Dragon-Slay3r]

🙀

[@ishraklaishrak]

Thanks for the explanation 🙏🏻

[@sofiehansen2887]

thank u so much, from Denmark

[@manyasahni1160]

Thank you

[@tanzimahmed2065]

Thank you very much for your explanation.

[@kissmyaxe9121]

Great video but i didnt want to see those images right before sleeping. Eww 😷

[@MohamedGad_]

Watching this video while having smallpox is crazy:( i wish it ended like u said in the video

[@2tell99]

I remember my parents getting vaccinated before they can travel over seas they had to have a vacs Card!

[@liston7649]

Always you are the best👏👏Love your way of teaching ❤️

[@Cloudnab]

i got extremely happy and proud by the end of the video

[@thesp1r1twalk3r]

Excellent explanation

[@JoshVandever]

..."that's the last time we're doing that! We didn't make money from curing it!"

[@joanmurphy2578]

Don’t let Daszak get his J fingers on this weapon.

[@medicalbiochemistry_]

Good👍

[@prashantsoren5226]

Please make cure method video

[@Jensenrobinb]

(Disclaimer, take your medical advice from doctors, not disease fascinated 14 year olds in youtube comment sections) Smallpox has ways to prevent it (vaccination or being born past 1980), but if you have already been infected somehow, the only thing we have is a drug called Tecovirimat. It was designed for if smallpox is unleashed back into the world, and due to extreme danger from working on the actual virus, they used it on closely related viruses (Monkeypox and rabbitpox, respectively) and it worked on the infected test animals, and had no health effects on non-infected human testers. TL;DR: we have little to cure it, and we probably won’t need to.

[@saidmaulanaibrahim3641]

Smallpox dangerous disease or not ? Any treatment for this?

[@Gremriel]

Did you even watch the video?

[@josecortez1268]

en.m.wikipedia.org/wiki/Smallpox

[@josecortez1268]

@@Gremriel, right!

[@saidmaulanaibrahim3641]

@@Gremriel but I still understand. Because for the people who live in rural areas they don't know about that

[@saidmaulanaibrahim3641]

@@Gremriel watch but I want to share knowledge for the people who live in rural area . That's why the disease danger or not it depends on treatment

[@gizelyferreira8035]

👏🏻

[@smallpox]

Did someone call me?

[@livestock9722]

Professor Dave - so... going back to the beginning, what makes a virus a virus? Is it alive, as in a biologically functioning organism? Why do "antibiotics" not kill a virus exactly, assuming they have the mobility and biological purpose to search and destroy? What makes a virus "tick" so to speak? I very much enjoyed you roasting the flat earth argument with logic. But with this virus matter, either the logic falls short or I'm a half wit. I'd appreciate your take on the matter.

[@ProfessorDaveExplains]

A virus is pretty much just some genetic material in a protein casing. They're categorized by their genomes and they're not considered living organisms. Antibiotics kill bacteria because they inhibit bacterial enzymes, like the ones that build their cell wall. You're not a half wit, you just haven't learned any biochemistry. I have many tutorials that can help you do that!

[@livestock9722]

@@ProfessorDaveExplains Thanks for the response. So a virus, being just some genetic material encased in protein, is inherently dangerous how? Inanimate material that has the "will" (if you will), to multiply and cause harm? Is there a biological purpose to this? Where did viruses originate?

[@ProfessorDaveExplains]

There is no inherent "purpose" to anything. Viruses simply exist because they are a pattern of matter that has replicative properties. No one really knows precisely how they originated, just as we don't know the precise origin of life, although we have a lot more of it worked out than most people presume. But viruses are dangerous to us when they infect our cells and disrupt cellular processes. Check out my biology tutorials for more background, and start this microbiology playlist from the beginning to learn about virulence and the mechanisms by which viruses infect and replicate.

[@livestock9722]

@@ProfessorDaveExplains "There is no inherent "purpose" to anything." Armed with this logic, why make a tutorial about anything at all, right? Jokes aside, I suppose one could take such an explanation or hypothesis at face value, and for others it provides more questions than answers.

[@ProfessorDaveExplains]

I don't really know what you're asking. We study things to understand them and sometimes thereby find applications to improve human life. With viruses the utility is obvious, if we understand viruses we can protect ourselves against them. We also utilize retroviruses in the medical realm, with techniques like gene therapy, etc. Don't mix up no inherent purpose with no potential purpose.

[@intellectualiconoclasm3264]

Great packaging and delivery! I had the vaccine in the early 2000's and it SUCKED! If the vaccine was that rough I have so much awe for the survivors of a full case. Just the physical exhaustion for a weakened vaccination laid a bunch of us out. The human body is truly amazing in it's ability to carry through!

[@rickkwitkoski1976]

REALLY? Why did you get vaccinated for smallpox then? Smallpox was totally eradicated by 1980 and routine vaccination for it was stopped.

[@intellectualiconoclasm3264]

@@rickkwitkoski1976 US Military manadeted them for pre-employment clearing before I deployed so I had to get the vaccine.

[@rickkwitkoski1976]

@@intellectualiconoclasm3264 Ah! Military! That explains it. Thank you. Anyone else that might have been vaccinated from 1980 onward would probably be in the same category.

[@intellectualiconoclasm3264]

@@rickkwitkoski1976 Most likely, or aid workers in the 3rd world. As much as I gripe I'll take the inoculation over the disease.

[@rickkwitkoski1976]

@@intellectualiconoclasm3264 I went to the "3rd World" in 1981. I was not compelled to get a smallpox vaccination AGAIN. At that point, in my international vaccination booklet (WHY don't we still have those!!!) a small note was stapled in saying due to WHO's declaration of eradication of smallpox, a vaccination was not required. I travelled a bit in Africa to several countries while I was there for two years. No one ever gave me any grief about smallpox vaccinations. Cholera, typhus, typhoid, yellow fever, polio, hepatitis... were are checked and I had them all current. Why you had something different 20 years later... dunno.

[@fenghualiu2653]

Is it only me feeling that the repeatedly represented pictures are disturbing

[@rickkwitkoski1976]

And rightly so. If those are disturbing and the fact that the virus and its disease have been eradicated due to VACCINATION!!!! Hopefully anti-vax idiots can put one and one together and see that their stupid ideas are total BS! Did you ever get: measles mumps chickenpox diphtheria whooping cough polio as a child? I got three of those. NO vaccines for them at the time and NONE of them were nice. I was sickest with measles. Yeah, I recovered, no vaccine. But many did not recover OR were left with lifelong debilitations. If such pics are disturbing... why aren't the reports of morbidity and mortality that are absolutely due to these diseases? Because they are ONLY lists of numbers?

[@hrishirajchkrabarty4428]

Yes

[@shaniajseph9586]

14th Btw his vids are very helpful

[@SumitSharma-py9ks]

Oh cool- when my mom was small she got smallpox and shes cured somebow and didn't even die-

[@rickkwitkoski1976]

How old was your mom and where did she live then? "... and didn't even die-" I guess not, since she had YOU!!! Very little, if any, smallpox cases occurred in developed countries after the 1960's. Anyone born up into the 1970's most likely were vaccinated against smallpox and WE ALL have a small round scar on our shoulders, left or right.

[@SumitSharma-py9ks]

Idk actually

[@SumitSharma-py9ks]

Well she was a kid -_-

[@rickkwitkoski1976]

@@SumitSharma-py9ks So, about what year might that have been? And where did she live? Curious as to why she had smallpox in the first place.

[@SherienElBehery]

👏

[@watyaam7266]

Smallpox: who are you? Monkeypox: i ur femboy son.