An important point was missed. The GWP effect is when there is a LEAK! not while it's in the system. When & IF it leaks when there is a fire, it will propagate the fire!!! Also, very important flammable A2L (R32 or R454B) might and could INTERNALY explode. This is true if the vacuum process (must be higher than R410A an A1 class non-flammable, non-explosive class) is not perfect (presence of moisture/oxygen) as when compressed the temperature could reach the lubricating OIL ignition temperature, and in the presence of flammable refrigerant (any A2, A2L or worse A3) the oil might ignite the flammable refrigerants! This possibility will not exist if A1 class non-flammable refrigerants are present. Neil Afram Director of Space Air Ltd. distributor of AC & Heat Pumps since 1980. Standards & Regulation relating to refrigerants classes ASHRAE 34/15 & ISO 817/5149