ACC 2020: Inclisiran Potently and Durably Reduces Ldl-c - Dr R Scott Wright

Dr R Scott Wright (Mayo Clinic, Rochester, MN, US) summarises a pooled analyses of phase 3 studies showing how Inclisiran potently and durably reduces Ldl-c.
Questions
1. What prompted the study?
2. How does Inclisiran work?
3. What is the study design?
4. Who were the patients?
5. What were the efficacy results?
6. What were the safety findings?
7. What are the implications of this study?
Filmed remotely from Rochester.
Interviewer: Victoria Perroud

[@jaqueitch]

Inclisiran is so promising. I wish I could take it instead of Welchol. I have been following Alnylam Pharma ince before its IPO in the early 2000's

[@erharddinges8855]

Outcome not promising, comparison to statins not useful, why not evaluating versus diet-succsess on metabolic syndrom ?( lowering sugar levles instead of cholesterol?)

[@humphreyfluffy906]

Another bio weapon?