Рет қаралды 629
Recurrent nevi which are a problem following shave and punch biopsies can be very problematical for the pathologist if the clinical history is not known. They may also follow other sorts of trauma, burns and even laser therapy. Although called recurrent nevi, this is really a misnomer as they represent re-growth of non-excised nevus. The junctional activity may regrow from the epidermis or the pilosebaceous structures. There may be severe cytological atypia and even slight Pagetoid spread. Mitoses are generally absent or very difficult to find. The lesion is best diagnosed at low power where the "Big Picture" is evident. The regrowth of junctional activity does not extend beyond the zone of scarring. Diagnosis often depends entirely upon the clinical history. Even then, it can be difficult as the prior shave biopsy may not leave a lot of visible scarring and the patient may have changed physician. Careful questioning is often necessary. I have found it good practice to try to review the prior biopsy just in case the specimen had been misdiagnoses as obviously melanoma can regrow just as eaily as a nevus. Distinction from melanoma with partial regression is stressed.