Understanding Cystic Fibrosis (Includes Pathophysiology & Diagnosis)

[@anushaaamir3522]

amazing lecture. really helped clear the concept.

[@krugmeister7301]

My Late Father Died of IDIOPATHIC FIBROSIS in 1989....He was only 59...Although he did smoke...Drank at times ...He seemed Healthly...His Sweat did smell salty...He did have weight on him before he Got seriously Ill....Which suddenly made him not able to go to work or do anything...He lost weight fast...And during his Ordeal at the Hospitals...He had a Collapsed Lung....It was awful for him...He suffered too much...And I HOPE and PRAY that their is a CURE FOR CF.!!🙏🙏🙏😑😑😪

[@bssah3088]

Very very clear explanation thank you 😊

[@linamariaruizperez358]

Amazing video, thank you

[@annyta2703]

Thank you so much! It was very clear & concise.

[@slytherin4254]

amazing, thank you so so much!!!!!!!!

[@ayapie2069]

Thanks for this!!! U explained well wow

[@samiaridhi2668]

Can u make a video regarding only bronchiectasis

[@JosephFrancis-i7x]

I don't understand why lack of chloride secretion causes increased sodium reabsorption though! That's the only hold up for me in the pathophysio portion. Could you explain?

[@PrideofPitchers]

My guess, sodium is attracted to negative intracellular environment from CL anions

[@JosephFrancis-i7x]

@@PrideofPitchers Thanks!

[@saphalpasupulati5949]

the electrochemical gradient created by lack of Cl- ions in the secretion decreases the efflux of Na+ by Na/K pump into secretions by ductal cells. basically a gradient is created with less luminal negative charge, hampering the outflow of positive charge.

[@saphalpasupulati5949]

@@JosephFrancis-i7x this is the explanation

[@saphalpasupulati5949]

there is also a mechanism where normal cftr inhibits ENaC helping na into secretions

[@arshdeepbhangu8884]

thank you ❤

[@Avacado_the]

It's mean if Cl cant move out outside sell minus increase inner of cell and then for Na try go in cell for increase plus charge. It's true

[@TheSedo88]

I wonder if this phenomenon is similar or the same if the person is only raw fruit? these observations were made on which dietary protocol?

[@omkardevang8611]

✨

[@ZEYADWALID77]

👍👍