Role of MHC Class I Molecules in Immune System | Basic Science Series

[@omrnour6287]

Thank you for this great explanation but you have shown the protein part of MHC, where is the carbohydrate part within the molecule? Thanks again 😊

[@BasicScienceSeries]

The carbohydrate part of the MHC molecule is integral to its structure and function, aiding in antigen presentation and immune recognition. Will discuss this soon, stay tuned Thanks! 😊

[@pmmp2801]

Wait but then how do these multiprotein complexes distinguish between endogenous and “strange” peptides in order to load them to MHC1? Increased transport rate or proteasome stimulated activity might be confused with some physiological acute stimuli, am I wrong? Great video btw! Keep on this, sending support from Spain!

[@BasicScienceSeries]

Absolutely! Cells have mechanisms to ensure accurate peptide loading onto MHC class I molecules, despite potential confusion from increased transport rates or proteasome activity. Thanks for your support from Spain! 😊🇪🇸