PrEP: Is It Secretly Dangerous?

Today we are talking about PrEP which is a drug you take, to prep in some ways to preventively not get HIV. Super fascinating! We know lots of people who are on it, so we wanted to talk about the science and the history AND if it’s safe.
Sources:
www.cdc.gov/hi...
en.wikipedia.o...
endinghiv.org....
dc-whi.org/wha...
www.cdc.gov/hi....
www.nature.com...
www.google.com...
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[@AliAliAli-c2e]

23:03 is where they talk about the side effects

[@elysantos5297]

Thank you very much

[@LightBlue9-f4w]

Thank you

[@colinf2316]

It's also important to keep in mind that HIV doesn't always respond to our treatments. My SIL works at NIH, specifically with HIV patients and she still loses patients due to HIV. My friend takes PReP and his doc orders blood tests every 3 months for the reasons you mentioned in the video.

[@loganwashere811]

idk if it’s available in canada but the fda approved an injectable form of prep in december 2021 but i haven’t researched much about it since, so if your interested in prep but not good at remembering taking pills then that’s an option on the horizon. loved the episode ❤️

[@ErickGuzmanx]

Love the podcast! I’ve been watching your videos since a kid and I’m sure it’s a big reason why science has always been my favorite subject! You guys make science, learning and education FUN!!

[@Gary_Texan_USA]

You guys have done a conscientious service for us MSM. I was lucky enough to live through the AIDS epidemic that ravaged so many of my friends and fellow Gay brothers without any meaningful treatments. It's gratifying to see two young men interested in the prevention and spread of HIV. ❤ Thanks 😊

[@BrandonCCB]

Even having 100% of my intercourses wearing a condom, I decided to get on PrEP. I had recently two accidents during sex and I had to go on PEP, wich gave me terrible side effects, so I decided to take continuously PreP so to avoid any future usage of PEP, which in terms of side effects for me was horrible, not to say the fear of contracting HIV after the exposure. Some guys do want to have unprotected sex claiming they are on PreP. All you have to do is say no. No one is forced to have a bareback boys.

[@sb8882]

Hi...how are you now

[@ftunnmnbar6268]

What medication have you taken after the PEP finish? Does the side effects gone? Please reply to me

[@BrandonCCB]

@@ftunnmnbar6268 no medicine after PEP was over. I just had HIV test to make sure I was not positive on the virus, and I was not. Been taking PreP consistently for one year now. No side effects. I have blood tests every 4 months to make sure my body is coping with the medication.

[@R21EMAN]

I always hear mitch talk about bbcan and so i finally decided to watch the season with him in it. I'm amazed at how strategic he was! that's so impressive.

[@Hi-vp3zu]

I went to pick it up from the pharmacy & was judged so bad. I’m at woman.

[@AlisaScholl]

The thing I heard a lot about condoms is, they don't fit very well. The last two partners I had, said they had bad experiences with condoms, because they were to tite. The guys didn't even know, there were different sized condoms

[@jjaredzz]

This was a really good episode. I was on PREP for a while when I was having more sex, it definitely created more peace of mind with HIV. I was scared of the risk of how hard it is on your kidney… and how bloated it made me the first couple of months. Also the way you all talked about it’s affects on other STI rates… I almost feel like I was more conscious on safer sex when not on PREP then when I was.. and I think a lot of other folks do to.

[@jjaredzz]

Also similarly as you talked about kidney functions.. in the US you have to get blood work every 3 months to make sure you’re still HIV negative and kidney function is okay.

[@evertonclayton32]

Have you stopped prep ?

[@Pippinking]

Here in the UK we are required to take a kidney function test before taking PREP. This reduces the risk of kidney damage to negligible risk.

[@flyingchong]

Episode ideas: -nuclear energy. The clean energy movement needs to stop demonizing it. -racism and xenophobia among animal lovers. It sounds very specific, but there’s this culture of people in developed countries demonizing people in countries they’ve never been to and exclaiming “how dare you kill this elephant?!… that’s been eating your hard-grown crops”. -related to prior - trophy hunting’s role in conservation. The animal activists make this such a black and white issue and it’s not.

[@sebastianmarkus]

No❤️

[@Richard-zy9sx]

Well done, you two. I was impressed by your knowledge of the issue.

[@aaronwright7266]

I'm always amused by people freaking out about STIs with anal sex yet never use condoms for oral sex. Gonorrhea, chlamydia, syphilis, etc., are all transmitted orally too.

[@j96993]

The risk with oral sex is not big with most people but anal sex unprotected is bad. PrEP affects the body more than people want to admit.

[@aaronwright7266]

​@@j96993 Not accurate. Countless people take PrEP without issue. And STIs are easily transmitted orally. You're entitled to your own opinions but not your own facts.

[@Vondarkstar]

10 stereotypes is 10 seconds bravo 👏

[@OneAndOnlyStormy]

I am so glad they have apretude because I would never remember to take the PrEP pills and they messed with my stomach when I would take it

[@TheJddmotta]

Hey ginger … please be kind and don’t talk when people are talking … just breathe!!!

[@TwinFalls88]

what's more important, the penetrative partner's short-term slight increase in pleasure ? OR your own health and safety as the much, much riskier position of receptive partner ?? = MAKE EM' WEAR ONE

[@coreydavis6427]

Step up to prep up.

[@elysantos5297]

Prep on demand

[@nicolasmora5118]

The comments are giving more then these dudes talking about it.

[@vincenthaegebaert1854]

I ❤ Dr Rubin. 😂😂😂

[@szvetozargligorovics9431]

You 2 at the same time.. toooooooooo. Much

[@TonyODonnell]

the funny voice is a side effect of being pretentious...........

[@Ursaminor31]

Any organic natural males left? Having never taken drugs or pharmaceuticals and never whored around, ready for a actual deep spiritual and physical connection on true partnership?

[@markharris6066]

Anyone left who asked 🤔

[@disneytoysr4fun975]

@@snnn4818nobody needs prep. You NEED to stop endorsing anal “sex” when the anus was absolutely not made for penetration. If gay me stuck with kissing, masturbation, and even oral we wouldn’t have this problem.

[@Michael-cl9mb]

Anal conection is not true deep connection.

[@Pippinking]

“Whored around” ??? FFS ! Statements like that just perpetuate shame, guilt and associations that gay men are risky and promiscuous. Maybe revised your ideas

[@Oscar_239]

Yeah here... virgin still and just want a monogamous relationship 😐

[@kensalazar5986]

YOU GUYS ARE Awesome 👍😎 I totally agree with you All ❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏❤️🙏

[@cmy5774]

Ive been taking PrEP for 2 years now daily. Had tons of hookups, mostly risky sexual activity and bareback anal sex and had been in a relationship with an HIV+ guy but he is U=U (which he couldnt transmit the virus even if im not on prep). Went well okay with me and Im doing good now. I regulary get tested every 3mos for all STIs and have my kidney function test every year. I recommend sexually active people to take PrEP as a form of protection. 😊

[@fToo]

Thanks for this. I've chosen not to be on Prep for similar reasons. However we do need to recognise that Prep has been phenomenal in reducing the number of new HIV cases in places where it is widely available. Here in the UK the health authorities are even aiming for zero new HIV cases by 2030.

[@hanz8933]

The best way u should to is do is abstinence then

[@thomasmercado5669]

They talking about everything yet breaking down nothing. They're not even getting into some of the topics that they want to talk about. They just keep saying yeah so we're going to talk about this and briefly go over it and then move on to something else

[@xavierheadbang]

I can't think of any men who are sexually active that wear a condom during oral sex, so if there's always a risk for all other STIs I'd prefer to be on prep anyways 🤷🏼🤷🏼🤷🏼

[@TShaloma]

Great explanation friends. Unfortunately, Truvada made me feel like I was dying with terrible nausea. Took it for a year because they said it would eventually go away, but it never did.

[@rayzamarripajr.7571]

14 mins on and it was about 10% science 90% social influencimg. ASAP science has gone down in quality no offense

[@OldManFishy]

I hate the phrase "safe sex" because ALL SEX comes with risk. I prefer "safer sex". If you are informed of the risk and prevention, you and your consensual partner(s) have the right to make a decision in what kind of sex you choose to engage in.

[@aaronwright7266]

When on PrEP, it's given for 90 days then bloodwork for HIV and kidney function is done for a renewal of 90 days. That's standard practice.

[@BlakeytheG]

Gay scientists are my favorite kind of people fr (I am also a gay scientist)

[@plantdanny210]

Can you guys make a podcast where you talk about DoxyPEP?

[@benbanks6302]

Does anyone know what the long term effects are of taking these drugs

[@sb8882]

Have you got an answer to this?

[@jamesjonnes]

Kidney failure, compromised immune system because it hurts the bones, and liver failure.

[@fragilous]

My father just passed away from a chronic illness related to his kidneys + liver, also related to having high creatinine. I'm also in a monogamous relationship for 10 years so we're opting out of PREP. But most of our friend in San Francisco are on Prep. And its very accessible. But I feel like they're also on other subst@nce a little too much :)

[@RenzoVodka]

Okay so why isn't anyone talking about the risk oral sex poses most of the time, especially considering NO ONE likes to wear a condom to either give or receive oral sex? It's great we have PrEP and condoms available but let's not lie and pretend unprotected oral sex is not an extremely, excessively common practice and that we do get sick both bacterially and virally from it.

[@Pippinking]

Because the risk of HIV infection through oral sex is 0.04%.

[@FlavioMarceloSousa35]

It's important to use PrEP properly. I was infected in May 2023 because I got careless and didn't take the right number of pills.

[@dalubhasar]

How are you now?

[@FlavioMarceloSousa35]

@@dalubhasar Doing great, thank you for asking. I take Juluca daily and I love it. No symptoms, no side effects, nothing.

[@dalubhasar]

@@FlavioMarceloSousa35 nice to hear you're doing okay 🙂 See you around then 🙂

[@syedmr4773]

So you got hiv

[@enteblu6799]

Were you taking on demand?

[@MrSurfingdreamer]

AWESOME JOB! I'm glad you talked about the facts that there are long-term effects of PREP and condoms are still totally necessary for protection against the many other STD/STIs.

[@JamesGrant-u2q]

You need to be on prep 4 to 7 times a week . The most protection comes from taking it after 7 days plus it easier if you take it everyday . If you miss one or two days you’ll be fine that’s why you should take it everyday . If taking the pills everyday too much they do have the shot which is every 3 months . I honestly think everyone gay or straight should take it .

[@PeterShieldsukcatstripey]

That was very helpful - especially the discussion about risk analysis.

[@KylePezzolla]

I’m watching Uncoupled and was like, “is this a drug that just exists in the show” I had no idea

[@adjusted-bunny]

Are you two gay?

[@916nene]

I just got prep and I’m confused some same don’t some do Idk what to do now

[@mello1960]

Do what use condoms.? I recommend that you still use condoms..I’m on prep too and I’m still kinda confused as well been on prep for about a month now

[@916nene]

@@mello1960 confused on to use prep or not for me it’s been a week and a lot of gays tell me to stop cuz prep will damage my organs over time

[@eddiev5782]

I was told the same

[@916nene]

@@eddiev5782 😩

[@yudeok413]

Don't listen to the gays. Go ask a medical professional.

[@AliAliAli-c2e]

You guys are forgetting that condoms don't really do a good job defending against skin-to-skin contact STIs in the first place..

[@yudeok413]

Sorry but what an inane comment ! Condoms don't protect against airborn diseases either. Come back when you figure out I how to have sex without breathing or any skin-to-skin contact.

[@cliveroberts8760]

boooost

[@sb8882]

Can someone tell me its ok to take prep for 28 days?...im really worried...and i dont want to be infected after exposure..pls can someone share some advice...

[@AJP1613]

If on Prep, its at its highest protective rate 7 days for anal sex, and 21 days for vaginal sex.

[@JM-zw8cq]

“needle users”😂 drug addicts u mean?

[@FakeApologize]

I take PrEP for monkeypox