I record all my guitar with an amp and a mic placed dead-centre. I quad track my guitar, and use 2 tracks for each ear. Each of the 4 tracks has a different tone coming from my amp's presets (I have a vox vt20x). All of them are full gain but aside from the presets I always tweak the eq, boosting treble and mids and cutting bass almost completely (my overall tone is very bass-heavy so I have to cut it so it doesn't get too muddy). I do this for two tracks, while the other two, which have the volume turned way down, also have boosted mids and trebble but the bass stays at 5. I do this for that extra punch in my tone. So my overall tone is a combination of microphone placement, amp presets, full gain and 4 separate guitar tones with high mids and trebble and low bass. Hope this helps!