Рет қаралды 101,982
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Hypnotics are the drugs which make a person calm but also induce sleep. This is an extension of a sedative dose of any drugs. Sedative in large dose act as hypnotics. The target of Benzodiazepine is on GABA receptor because GABA is a major inhibitory neurotransmitter in CNS. GABA is consisting of five- alpha, beta, gamma subunits that span the postsynaptic membrane. The influx of chloride Ions cause hyperpolarization of the neuron and decrease neurotransmitter by inhibiting the formation of action potentials.
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