Spermatogenesis Made Easy

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/ medsimplified
Spermatogenesis is the process in whichspermatozoa are produced fromspermatogonial stem cells by way of mitosisand meiosis. The initial cells in this pathway are called spermatogonia, which yield primaryspermatocytes by mitosis. The primary spermatocyte divides meiotically (Meiosis I) into two secondary spermatocytes; each secondary spermatocyte divides into twospermatids by Meiosis II. These develop into mature spermatozoa, also known as spermcells. Thus, the primary spermatocyte gives rise to two cells, the secondary spermatocytes, and the two secondary spermatocytes by their subdivision produce four spermatozoa.
Spermatozoa are the mature male gametes in many sexually reproducing organisms. Thus, spermatogenesis is the male version ofgametogenesis, of which the female equivalent is oogenesis. In mammals it occurs in the seminiferous tubules of the male testes in a stepwise fashion. Spermatogenesis is highly dependent upon optimal conditions for the process to occur correctly, and is essential for sexual reproduction. DNA methylation and histone modification have been implicated in the regulation of this process.[2] It starts atpuberty and usually continues uninterrupted until death, although a slight decrease can be discerned in the quantity of produced sperm with increase in age
The entire process of spermatogenesis can be broken up into several distinct stages, each corresponding to a particular type of cell in human. In the following table, ploidy, copy number and chromosome/chromatid counts are for one cell, generally prior to DNA synthesis and division (in G1 if applicable). The primary spermatocyte is arrested after DNA synthesis and prior to division.
Spermatocytogenesis is the male form ofgametocytogenesis and results in the formation of spermatocytes possessing half the normal complement of genetic material. In spermatocytogenesis, a diploidspermatogonium, which resides in the basal compartment of the seminiferous tubules, divides mitotically, producing two diploid intermediate cells called primary spermatocytes. Each primary spermatocyte then moves into the adluminal compartmentof the seminiferous tubules and duplicates its DNA and subsequently undergoes meiosis I to produce two haploid secondary spermatocytes, which will later divide once more into haploid spermatids. This division implicates sources of genetic variation, such as random inclusion of either parental chromosomes, and chromosomal crossover, to increase the genetic variability of the gamete.
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[@jaiameecham1495]

Love how I can understand this clearly in 4 minutes than listening to my prof for a whole semester... thank you!

[@nuwanekanayake5791]

😉 U r lucky cuz we have to learn this before going to university... in our schools

[@catchflightswithfiona9696]

came here for this comment!!

[@bigzo6746]

@@nuwanekanayake5791 same bro same ... life science paper 1 on Friday ... all the best my guy

[@nuwanekanayake5791]

@@bigzo6746 good luck to you too bro 🙏

[@sanaullah3353]

Where are you from

[@DanielCamargoTalks]

In case anyone was wondering, this entire process takes 70-90 days to reach the mature sperm cell stage.

[@HashemSmashem]

@2:15 type 'A' spermatogonia are the ones that maintain the stem cells, type 'B' are the ones that proceed with spermatogenesis to give rise to primary spermatocytes. Not the other way around.

[@dr_ismail_wazir]

👍

[@jakjaksangma1041]

Why don't you make your own video

[@Denizyarsuvat]

Thank you, I was so confused.

[@silverpeetersiiak3377]

Reading this from Nieschlag's "Andrology" as well right now.

[@petreuseedward5754]

Thank you so much because it really had me confused

[@beerancis8685]

Guys come on - if you think he's speaking too fast for you just slow it down using the settings gear to 0.75 or 0.5. This is an excellent video @MEDSimplified, thank you for taking the time to make it for us.

[@elliottm5662]

Never usually comment on these things when I am revising but I felt that this video was so helpful I should definitely comment. Thank you very much for such a very useful video!

[@MEDSimplified]

+elliott man I am glad Elliott. :)

[@emmanoel4876]

To those saying he is speaking too fast, go onto settings in the video > speed > 0.5 Should solve your problem. Put on subtitles if it helps.

[@adnanmumtaz1697]

Omg Allah apko khush rkhy 2 gnty ka lecture dia sir ny smj ni aya .. But apny 5 min ma smja dia....bht Acha bht bhhhhhhttttttt

[@stephanvandan893]

This video really helps me to prepare for my science exam tomorrow. Tip of my hat to u man🙏🙌

[@HiMyNameIsLoay]

Finally I understanded it very well. Easy and clear, thank you sir ❤️

[@carmelpule6954]

Many comments below state clearly, "that they have understood the process" when I doubt what they mean by understood the process. All they have done is follow someone describing what they call a few things that exist, so they can repeat the same sound or write it down elsewhere, I feel certain that no one did understand the process and they are merely capable of quoting the convention we use to communicate, BUT REALLY NO ONE DID UNDERSTAND. THE REAL DETAIL. Repeating what one hears is not understanding. If one says that walking is a case of conducting one step after another to move from one point to the other does not mean one knows anything about the real detail of walking!

[@lohishome8568]

Thank you so much for helping students by making the topic more easier to understand.

[@Priya-zd3is]

Omg, thank u soooo much! I'm in Grade 12 and didn't understand any of this is the 2 weeks that we spent learning this! U completed my entire unit in 4 minutes lol! ALREADY SUBSCRIBED TO UR CHANNEL!

[@czechmeoutbabe1997]

Wow this actually makes sense! Thank you so much for this!

[@takeouttherubbish]

this was soo helpful, the corresponding drawings really help organize this process

[@MEDSimplified]

Thanks. I am glad you enjoyed the video

[@grunktabulous]

Amazing video, really helped me for my test! Thanks a lot man

[@mathayelghali4273]

This video was so HELPFUL to me!!! Thank you so much 😊

[@Lauren-yn9go]

Your videos make studying so much easier. Thank you.

[@alialn9049]

the best explanation I've ever heard. thank you so much !

[@darpmosh6601]

@2:15 type 'A' spermatogonia are the ones that maintain the stem cells, type 'B' are the ones that proceed with spermatogenesis to give rise to primary spermatocytes. Not the other way around.

[@nestorpelagio4393]

Yes i did ' i've found it very helpful bro, simple & easy ,huge thanks ' hat's off , shame on my prof 😂😂😂

[@mangenjoshua4566]

this is so brief and precise, i am so greatful.thank you

[@deepakkumarnayak6341]

tomorrow is my xm and this video clear my concept thx sir for this beautiful teaching

[@gautham4246]

Hats off bruh.. Your videos helps to understand easier.. Than any book

[@heidirodriguez1093]

This helped me so much. Thank you much!

[@Palak-tr2ws]

Thanks for the vedio. Your vedio was very very helpful. And your way of explaining is the best ,it created a systematic image of the topic.

[@yogayantra]

don't worry for your Indian accent--which, if we accent the American prononciation-- just has to be accepted as it is. It took the first 3 seconds to adapt myself, and i understood you perfectly though I am not a native English speaker. And for those who find it;s too fast, just go to 'setting" (the little wheel) and change the speed!

[@kavishajajriya3122]

Thank you so much sir for this most helpful video,you teach us the whole process of spermatogenesis in just 5 minute love watching this 👌👍👍👍👍most helpful ❤️must watch 🔥❤️

[@atharvakendre3047]

Pls some one tell how many layer does siminiferous tubule have and plz mention from where do you get it

[@anishasarkar4675]

@2.15 Actually half of type A spermatogonia are dark A1 cells which maintain stem cells and another half are pale A2 type undergoes mitosis to form B type which further undergoes growth phase to form primary spermatocytes.

[@didar6588]

Good job pal, you also got a great channel! :-)

[@989tu8]

Thank you so much. This explaination is just great 👏🏻👏🏻👏🏻👏🏻🙏

[@Extman]

Well organized video thank you so much for this wonderful piece 👌

[@UHFStation1]

I'm confused. How is epigenetic information maintained in sperm but lost in other cell types when Yamanaka factors are turned on?

[@anushkamandekar6010]

Very useful 😄👍....You got a new subscriber

[@quockhangho8440]

Thank you for your video, very informative and easy to understand.

[@darwinradhi9350]

Thank you for your simplified explanation.. Really helpful

[@shivangi3452]

Thank you so much ... Very very helpful ! Concept clear ✨

[@deergasikumwrswai6850]

Sir keep going on that which can help in our studies. Thank you sir

[@shonalichoudhury1308]

So helpful and simplified.. thank you 😃

[@ivmusic5404]

Great video. Understood everything easily.

[@NataliaSegreto]

this was really helpful, thank you!!

[@majtodd]

Very helpful and concise explanation. 👍

[@12debaduttadas23]

This is the best video i have ever seen

[@ankitatewari6073]

Omo uh r a bst teacher nd instructor ..thnkuhhh so.much fr this ❣️. actually i m feeling blessed tht i found out ur channel.... thankuhhhh sooo much..❣️

[@BioScienceShorts]

Thank you so much..its way easy than i thought...you made it easy

[@tarunssangha7605]

Thanks mate, really helpful video 👍

[@peacelover8245]

Thank you very much for this. How long does each phase take and when does meiosis occur with cross-over/recombination? I believe I read an article that the mature sperm and egg have each already had some mutations / recombinations

[@christinea3455]

Thanks for the video!

[@finickyaman3412]

I have a doubt plz help. In meosis 1 the homologous chromosome exchange gentic material so then when cell divide they are different to each other, is it the same in this case also or is this meosis a little different?

[@jumims123]

Wow. Thank you that was so easy

[@angelomatteooliva2819]

Very useful video! I really enjoy it!

[@ssmv9139]

Thank you Brother. Nice way of explanation ❤️

[@doodelay]

Im always amazed that we even know all this

[@maureenganga1512]

This is easy to understand in minutes

[@abdalla8558]

That amazing, make more videos plz so helpful

[@muhammadasad4949]

Which recorder do you use for recording this video?

[@garimabirhmaan8370]

thank you for making this video

[@surenjos2271]

Having a doubt .. At 3:45 , Whether the enzymes of Golgi bodies form Acrosome ( As per Ur Writings ) or if the Golgi bodies form the enzyme of Acrosome ( As u said ) ... ???

[@mamtakumarisingh9266]

This vedio is so helpful to learn about the spermetogenesis

[@hiranisar6258]

Thanku soo much for making this easy conceptual video

[@dd4300]

Superb.. What is your video editing app??? Please telll...

[@geethamanoharan8627]

Beautiful explanation thank you so much

[@xyzabc1924]

This video is so helpful for quick revision .Thank you sir/ma'am. I am glad that I found this channel but am not able to find video of oogenesis.

[@Zee-shanAcademy]

KZbin/zee-shan academy

[@reemsaleh8832]

lovely !! very simple & helpful

[@Kate-hu9be]

Thank you so much for forming this video ✨🏆

[@Adell1721]

And what about the germ cells? How is it possible that there's still plenty of them even after daily spermatogenesis. Are they divided by mitosis?

[@SaddamHusain-zf9ce]

Thank you very good explanation my doubt is clear

[@samuelphetole1008]

Thank you for the video

[@sadikaabony461]

Thanks for this nice explanation.

[@relchan489]

thanks, its helpful with my education👍

[@malavikaunni5764]

nice video.got very helpful.thank u so much

[@laliudaya2603]

Abosulutely perfect video for easy understanding ❤

[@That_misfit]

Tnqqq sir... Jo smjhaya vo SB smjh m aa gya.... and Congo u have a new subscriber 😂😂😂😋

[@tehminasabir3034]

Thank u so much....it was helpful

[@subhasubha3147]

Very clear explanation tq so much😊

[@jakjaksangma1041]

Thankyou, this video helped me so much thank you

[@saharmohamed711]

very helpful thank you

[@anishpaudyal3392]

Awesome Video Thank you Sir😊🙏

[@smrutimayeesi6022]

Thank you for the video Sir.

[@ai3meu295]

Hi... Can i ask what's the parent cell of the spermatogenesis? I just need it for my assignment today Pls.Thanks😊

[@ayushagarwal5429]

This video is superbb sir I can understand whole process

[@user-kw4ro1tn1e]

So helpful thank you

[@gayatrisahu2284]

I think u r the best KZbinr for me...but y u r not making videos on lactation mensuration cycle 🥲...

[@futurepharm1776]

thank you, you were very helpful :)

[@katelyndenisco8971]

Thank you so much for the help!

[@MEDSimplified]

Happy to help!

[@nyawirawaithaka4993]

Very helpful. Thank you

[@sreekalavinod6212]

Wow.its really helpful.thank u sir .

[@vivekVerma-el1yw]

Thank you sir it's so helpful for me

[@ButterflySimmer]

very useful but could you put subtitles as i has to rewind the video many times as i can't pick up on what you're saying

[@twinkle1548]

Very well explained👍💝

[@josephinerose92]

I liked hearing your kid at 2:35 haha.

[@MEDSimplified]

+Josephine Coury You have a suberb Cochlea mam!

[@yashambekar0025]

Observation 💯

[@mendina2842]

HAHAHAHAHAHA

[@anishpaudyal3392]

This video is Wow! Thank you Sir😊🙏

[@positivevibes7425]

I really like ur explanation!

[@Anna_kandy]

You have a good voice!

[@hakai6234]

Very very helpful, thank you😁😁

[@rubinabegum2142]

Thank you 🌹 "God bless you brother "

[@supriyak4100]

Just wow video ❤ to the point nd crystal clear

[@ecconamalashika.a8511]

This video is very useful for me Thank you sir

[@himanshimishra9208]

Nice vedio made my concept clear

[@triluve]

Forgot to mention the time it takes for the whole process.

[@sumitragupta183]

Superb explanation