Longevity and Aging in Humans

[@howellwong11]

At 70, I set my expected life span at 84. Now that I am 89. I have set it at 94. Soon it will be 100, I hope.

[@hasilsembiringco-id222]

what wonderful lectures. entering my sixties, I learn that these lectures are really useful. Thank you so much.

[@rodeo179]

the core of lecture (minus introductory graphs) starts @ 21:11 thanks for posting!

[@apexxxx10]

pelikan w 21:11 *Thanks *AGING an DRIVING. JOHN K. LINDGREN* kzbin.info/www/bejne/jIDKmHSshdp_o68

[@Featureman]

I met Ronnie Fairbanks who claimed to be 107. He might have been. He was in excellent condition. I do have a video with him called Longevity. Your advice in this video and the study in general of aging factors is interesting and very important for each of us. Thanks.

[@nneichan9353]

Two of my favorite doctors were trained at Harvard (in the same class!).

[@carrollhoagland1053]

Interesting talks, as many are by passing doctors (they have no real training - just regurgitate other sciences) and trying to understand these topics. Doctors diagnose after we are sick, it is the patient who needs to be proactive. Therefore intervention in the aging process becomes the target ... Simple ... The AMA (the most powerful lobby in Washington) and NIH have failed the patient ... Physicians have abandoned the nutritional approach to patient diagnostics and medicine, simply because they are not trained in nutrition. A key part of the Hippocratic Oath ... “I will prevent disease whenever I can, for prevention is preferable to cure... “, has been forgotten … 70 Going On 100 ... the Centenarian Diet

[@dr.aardsmasvitamins8605]

Another perspective is that aging itself is a preventable disease, with a specific cure.

[@wmp3346]

What else is new, people are selfish and act in there self interest not others

[@TheBartBarton]

This presentation completely ruined by an overly eager crowd interrupting the flow and competing with their questions. STFu and let him finish, then ask the questions.

[@tonifelise6297]

What ages and kills people is life, the kind of life you led, its very individual, some people get lucky and have more happiness so they live longer

[@Shaunt1]

A very important subject with useful info. I'd like to see more done in this field.

[@mjpucher]

Dietary restriction will kill your metabolism if done wrong. You need to properly fast or intermittent fast with low carb and do High intensity resistance training to stop muscle loss.

[@ImAnElephant89]

Penn Foster Herbal Studies sent me here!!!

[@colinmaharaj]

1:01:27 Anne Brunet part

[@cellhealer]

my longevity club members saw this video and like s it , I work on longevity with my personal longevity machines

[@Maxdud]

That's Amazing! We have a discord server talking about longevity and there are actually people in the field who are scientists in longevity and have met these famous names! discord.gg/ftSbffu Here is the Link if you wanna join!

[@cellhealer]

I m actually Science Director in 2 research centers and in charge of Longevity developy machines

[@lindacyoung1789]

Linda C Young.

[@futuristiclettuce]

Believing in something out of fear, in your case believing in God because you fear going to hell, is not the right way to go about deciding what to believe in.

[@arttoegemann]

Growing young. Master aging at the genetic level.

[@wvhdogg]

useful information

[@frv6610]

at 48:00 Thomas mentions heterochronicity. did it increase lifespan of the older mouse? can the young mouse be genetically modified for connection with a human to rejuvenate the stem cells?

[@grunder20]

No one can stop aging. It is nature.

[@wmp3346]

Not true

[@wmp3346]

Pre IF?

[@blacklegsanji3339]

Im not so sure if there is muscle cells in the nervous system, i think that its actually the only place where there are non.

[@SinghTheMaster]

thanks :) you saved our 21 mins

[@apexxxx10]

D Singh *”TIME” THAILAND INTERNATIONAL MOTOR EXPO* kzbin.info/www/bejne/e3y3qaqDhdOJZ68

[@adriatik7070]

with caloric restriction it just feels you living longer cause one is miserable and hungry …lol

[@fordicidia6361]

The pleasures of life are not merely culinary. We should eat to live, not live to eat.

[@beingnonbeing]

What is the date of this lecture?

[@colinmaharaj]

beingnonbeing don't worry, it is still relevant :)

[@andrewlace55]

Start at 21 minutes!

[@nobelminds7955]

No.

[@xtremetom180]

great vid you have here

[@MrDeshrine]

I recently did a 23andMe DNA test and found out I have the FOXO3A gene SNP(single nucleotide polymorphism) rs 2802292 (G;G) which is the exceptional longevity gene. I can't help but think that's due to the previous three years I've been practicing cyclic fasting 23h fast and 1h feeding in combination with caloric restriction. I also have engaged in both aerobic and resistance training for the entire duration. I feel as though this gene has been expressed through epigentic change. I'm quite excited to say the very least. I follow the Age Inhibition Regimen by Dr. Nun Amen Ra.

[@blakehernandez1304]

What?? Your diet doesn’t affect your genetic code. Not unless you’re eating Uranium

[@MrDeshrine]

@@blakehernandez1304 Well, part of epigenetic genealogy is how we understand how nurture, or environment, can have an effect on nature, or genes for that matter. Particular genes can be expressed or turned on depending on chronic lifestyle choices and circumstances, like smoking and chronic stressors. Further, those newly expressed genes can be passed on to offspring, which is one of the best ways we can observe evolution of species. It's somewhere in that ballpark

[@blakehernandez1304]

Deshrine Ussin i think you misunderstand the term “gene expression”. If a gene is expressed, it simply means that the protein corresponding to the gene is being produced. This does not alter your genetic code.

[@MrDeshrine]

@@blakehernandez1304 See, I never made the assertion that diet or lifestyle change genetic code, only expression. I understand epigenetics aren't relating to code sequence but gene activity. Most people possess the same genome, heredity, environment, and transgenerational epigenetic inheritance play a role in how they are expressed determining what alleles of specific genes one carries. Maybe I'm wrong, but that's how I understand it. For instance, chronic activation of AMPKinase, an enzyme that is active in caloric deficits and endurance training, can alter the expression of FOXO3A, in fact, those who do not inherit (G;G) alleles, can only alter FOXO3A through AMPKinase and inhibition of mTOR, and IGF-1.

[@blakehernandez1304]

Deshrine Ussin my main comment was that your lifestyle and diet have nothing to do with you having a particular SNP in the FOXO3A gene. That is already determined when you’re born

[@social3ngin33rin]

Enjoyed all 1 5/6th of an hour :)

[@unclegrim]

Stop asking questions and let the man finish his lecture, goddamn!

[@jessiewest4153]

Yes the asking of so many questions is very annoying.

[@Reynoldsrobert]

I wonder how much of the first doubling in life span which happened over many thousands of years was due to the ratio of mega fauna predators to humans changing over time. Traditional archaeology says it took us a million years to VERY SLIGHTLY improve sharpened stones, so they have little claim to lay that it had anything to do with technology. (Traditional archaeologists are, unbeknownst to them, the world's foremost experts in brain washing, if only by experience! Haha, after all, anyone presented those theories that hadn't had their common sense somehow dramatically weakened, would know better! But that is what our educational system is focused on, BRAIN WASHING!)

[@Reynoldsrobert]

When uploading a video with slide presentations, it's good to upload with AT LEAST 720P. (Many watch these presentations on their phone, although that doesn't matter). Even blowing up slide photos that are done at 480, the fine print cannot be read. (No matter how good your vision is)

[@gs-nq6mw]

Lol,thats a 2010 video

[@chunglee6895]

Stop those questions until the lecture is over! moderator is not doing his job.

[@theequaliser8026]

Umm

[@life42theuniverse]

Hmm, So vampirism is a way to live a long life. Consuming the blood of the young...

[@astroboomboy]

Actually that is a statistical error. Because most people have faith on God(s), the comparison is between an extremely large group, and a very small group, which means that the average life span my be quite similar, but a larger group will have more likelihood of more people living longer. I remember reading this quite recently by a statistician, which I remembered where.

[@davidtraversa]

Astroboomboy. You should check your statistics. In Germany the church --evangelists and christians-- have sold 400 temples already because people are stoping in droves going to churches and the business is no good anymore, 150.000 people a year are leaving religion because with more education, they are seeing the flimsy fairytale they had been told for centuries of ignorance. Try watching some very fascinating people on the Internet that will explain you some issues in very easy talks.

[@guestuser2373]

She can say DZZs to me any day.

[@happyandhealthy888]

aGING AND LONGEVITy

[@ELZOOL12]

I cannot believe how rude these students are. Ask your questions after a presentation. Give the guy a chance to fully explain himself before you interrupt him.

[@defenderoftheadverb]

There's a statistical correlation indicating people of faith live longer too. Trouble is belief is not qualified by need or virtue. You either believe in god or you don't. There is no rational proof. Those who believe do so irrationally.

[@RaffiTheQuokka]

Well, I think prayer and meditation are very similar, and this mechanism has significant benefits (lower stress hormones, better sleep...)

[@TjenkinsandAige]

"evolutionary design"? : oxymorom.

[@kotyto]

He is misinformed. We seem to know why very old individuals die eventually. Seems a very old autopsied individual, had only a few stem cells renewing her body for about 5 years :-)

[@TjenkinsandAige]

"evolutionary design"? : oxymoron.

[@pauljones5066]

live a long and miserable life folks

[@wmp3346]

Watch Fox News

[@kotyto]

Another *** ranting "oxidative stress". Hehehe maybe mayflies or turtles are subject to a different regime environmental stress :-(

[@dysvanlist]

@JohnJayRambo1 Why didn't you link this to my comment? I would have never seen it if I didn't check. As for your comment. I'm very sorry my friend, but you've been brainwashed with metaphysical nonsense. If you want to present your physical evidence, please present them with a personal message.

[@suzibelle3995]

A recitation of a long-list of boring statistics is of no practical use to anyone seeking to live longer. Thomas Rando is a narcissist in love with his own superiority complex.

[@dysvanlist]

@JohnJayRambo1 God doesn't exist