Status Epilepticus in children

[@vincemusicpro4721]

Thank you so much. You made my life easier a day to my final clinical assessment ❤

[@DrMK7]

I’m glad the content is helping

[@loveulunjie]

Easy to understand content! Can't wait for more videos!!!

[@brendonmoyo566]

all I can say is wooow! This is really life changing

[@brendonmoyo566]

may you please do a video on acute liver failure and maybe a series on blood and congenital heart diseases

[@DrMK7]

I'm glad it is helping, will work on more content

[@NegoMu]

This was an amazing lecture, well explained and easy to understand. Thank you for the knowledge Dr. MK

[@DrMK7]

you are welcome

[@ABDIBAASIT]

absolutely, this was an amazing lecture, well explained and easy to understand. thanks Dr.

[@DrMK7]

Glad it was helpful!

[@medleymedbylily3891]

hey, do have a video of celiac disease in pediatris please?

[@DrMK7]

No not yet

[@marthalutangu3853]

I needed this, thank you Doc

[@DrMK7]

you’re welcome

[@harithzaytoon4526]

thanks for that amazing illustration doctor could you drop the slides that had been used in the video please

[@DrMK7]

arranging for that

[@harithzaytoon4526]

@@DrMK7 Great, i wish the best for you. Doctor it will be kind if you give us notification when you upload them. والسلام عليكم ورحمة الله وبركاته

[@worldnature6185]

thank you so much dr

[@mercythought]

I love this. Can you do more on childhood seizure?

[@DrMK7]

We will work on one

[@kingmarlow7534]

How does blockage of NMDA receptors by mg2+ cause epilepsy.i thought that would be rather a protective mechanism against epilepsy

[@DrMK7]

Remember the NMDA receptors are a type of glutamate receptor that play a crucial role in synaptic plasticity, learning, and memory. They are also involved in regulating neuronal excitability. The Magnesium ions (Mg2+) act as a natural blocker of NMDA receptors, preventing them from being activated by glutamate. Naturally When NMDA receptors are blocked by Mg2+, it can lead to a decrease in neuronal excitability. This is because NMDA receptors are important for generating action potentials. When NMDA receptors are blocked, neurons are less likely to fire action potentials, which can lead to a reduction in overall brain activity and this explains the use in management of seizures… However, in some cases, blocking the NMDA receptors can actually lead to increased neuronal excitability. This can happen when there is a sudden increase in the concentration of glutamate in the synapse. When this happens, the Mg2+ block is removed from the NMDA receptor, allowing it to be activated by glutamate. This can lead to a sudden and excessive influx of calcium ions into the neuron, which can trigger a cascade of events that ultimately lead to seizures.

[@ewaoluwaogunbodede9917]

@@DrMK7 hi sir, I’m still not understanding the pathophysiology concept

[@reginamutupa7696]

Wow thank you for the good lecture, I have a question why do we use phenobarbitone as a first dose in neonates, what's the physiology behind that??

[@DrMK7]

with Phenobarbitone does not not only control seizures but also reduce the metabolism of the brain; so it also has synergistic neuroprotective effect when applied with therapeutic hypothermia, which is now considered as standard management for term newborns with moderate to severe encephalopathy for example

[@reginamutupa7696]

@@DrMK7 thank you so much Doc🙏

[@sean117xx]

Thanks doc, this is really informative

[@DrMK7]

Glad it was helpful!

[@doctorbaba4880]

Great video🙌🙌

[@DrMK7]

glad you liked the video

[@patriciamwango1024]

Awesome 👏🏻👏🏻

[@DrMK7]

Thank you! Cheers!

[@natashamwenda9024]

This was a great video.

[@DrMK7]

Glad you enjoyed it

[@nthembemwanza5957]

Thank you 😊

[@MzChosenByGrace]

❤❤❤ Bless you my friend

[@DrMK7]

You are so kind

[@tony_eppy]

please make a video on congenital heart disease

[@DrMK7]

I did one on TOF

[@blessingmwale4260]

Your videos are the best

[@DrMK7]

I am glad they are helping

[@happychunda1735]

Lovely lecture

[@DrMK7]

Glad you liked it

[@aminaismaciil3354]

thank you so much dr

[@DrMK7]

you’re most welcome 🙏

[@MunaElnemr]

Good content

[@DrMK7]

thank you 🙏

[@AsiyaPhiri-to1mx]

This video was very helpful thank you so much Dr Kazevu🙏

[@DrMK7]

Thank you

[@katchingkisses6729]

Jaundice video please 🥺

[@DrMK7]

Neonatal jaundice?

[@katchingkisses6729]

Yes neonatal jaundice

[@DrMK7]

kzbin.info/www/bejne/jYnao4yBjsyFqK8si=4yhCWobuEeNWzIoj

[@nalukuimukelabai7128]

Exam tomorrow wish me luck

[@DrMK7]

how did it go ?

[@ronefana4015]

♥️

[@DrMK7]

👍

[@munakampemajorita9753]

We are waiting for more videos on seizures

[@DrMK7]

Noted 💯