Study of acute oral toxicity & LD50 of a drug from a given data |Miller & Tainter |Karber's Method

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About video:
1.Definition of toxicity and LD50 Value (Time line 0:36 to 2:15)
2.Type of toxicity studies overview (Time line 2:17 to 4:24)
3. Acute toxicity class method-OECD 423 (Time line 4:25 to 11:43)
4. Comparison of OECD Guideline 420 i.e fixed dose procedure, 423 i.e Acute toxic class method and 425 i.e Up and down procedure (Time Line 11:44 to 17:42)
5. Sighting study (Time Line 17:43 to 19:59)
6. Observation Period (Time Line 20:00 to 20:59)
7. Limit test (Time Line 21:00 to 24:47)
8. Subacute and chronic toxicity test (Time line 24:48 to 26:42)
9. Application of toxicity test (Time line 26:43 to 27:24)
10. Demo for LD50 Calculation
A. By Miller and Tenter method or by probit analysis (Time Line 27:25 to 43:19)
B.By Karbers Method (Time Line 43:20 onward)
For better visuals watch at the quality of 480 or 720 p
Reference:
Guidelines: 420
ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd_gl420.pdf
Guidelines: 423
ntp.niehs.nih.gov/iccvam/suppdocs/feddocs/oecd/oecd_gl423.pdf
Guidelines: 425
www.oecd.org/chemicalsafety/risk-assessment/1948378.pdf
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[@selaletube7121]

I am so thankful for the brief and very precise video Dear Dr.

[@AbhishekSingh-pm6bs]

Very good 😊

[@nabila_di_08]

Excellent delivery

[@SirajShaikh-xg9fi]

Very good session

[@foramparekh2104]

In calculating SE the formula itself saying logLd84-logLd16 ÷ root2N so after calcutating ld84 and ld16 we don't require to find log of that and after finding log we have subtract ?

[@khanFaisalYusuf]

Mashallah

[@muddasirpatel1078]

20DPH05