SURE-01/02: sacituzumab govitecan and pembrolizumab for MIBC

Antonio Cigliola, MD, IRCCS San Raffaele Hospital, Milan, Italy, discusses the findings from the SURE-01/02 trial (NCT05226117) investigating the antibody-drug conjugate (ADC) sacituzumab govitecan (SG) alone or in combination with pembroluzimab, for patients with muscle-invasive bladder cancer (MIBC). The study was carried out in patients who refused or were ineligible for cisplatin-based chemotherapy. A majority of patients completed four rounds of SG, and pathological complete response (pCR) was seen in nearly half of patients who did not receive a radical cystectomy. This interview took place during the 2024 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
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