Tablet friability testing in Pharmaceutical industry l Friability test Interview Question answers

Tablet friability testing in Pharmaceutical industry l friability test apparatus 16 Interview Question and answers
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Questions covered:
Q. What is the purpose of the Friability test in pharmaceutical industry ?
Q. For how many rotations we should rotate friability test apparats and at what RPM ?
Q. How many tablets we should take for friability test?
Q. Describe the procedure for conducting a friability test on tablets ?
Q. Why dedusting is important prior to friability test?
Q. What are the required specifications for drum used Friability test apparats ?
Q. Which USP chapter talk about Tablet friability testing ?
Q. What is formula for calculating friability and what is acceptance criteria ?
Q. What is relation between friability test and tablet hardness ?
Q. When we should repeat friability test as per USP chapter 1216?
Q. When we should tilt drum during friability test and at what degree ?
Q. When we should perform tablet friability test?
Q. What are the calibration parameters for friability test apparatus ?
Q. Why standard rotation is set 100 ? Why not 90 or 110 ? Why only 650 mg tablets are taken for test ? Why standard RPM is 25 ?
Q. Any case of tablet final wt. Is greater than initial wt. It possible or not ?
Q. Which are the commonly used guidelines for friability test in the pharmaceutical industry ?
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