Terminal Sterilization Cycle Development

[@brajendrakumar4198]

Nice lecture sir

[@kichootv]

kzbin.info/www/bejne/j3Tbd59_i9t9fLM How To Develop Terminal Sterilization Cycle? Why Air Removal not required in Terminal Sterilization? Why Vacuum not required in Terminal Sterilization? What is D Value? What is F0 Value based Sterilization Cycle?

[@kamalkishorpant9720]

Many many thanks Sir for teaching , gratitude 🙏

[@nitinkmahajanmahajan223]

Nice video

[@bhupendrashukla1972]

Useful

[@nirmalsartana4061]

Very nice sir

[@tarunthakur2009]

Many thanks sir

[@PHARMAVEN]

Thank You For Your Appreciation, Kindly also share to your friends and groups and juniors 🎉🙏👍

[@pukhrajmaske7047]

Sir hindi me sabhi video bano

[@Helmet_red]

Sir could you please explain about the ventilator cycle in brief please

[@BrandBabuSoni]

Hindi me bhi bana do ek video

[@Animal-m5y]

How to detrmine fo value using bacilus subtilus at 108 degree for 60 min

[@ManishKumar-fp3wn]

Which guidelines refer terminal sterilization.???

[@kalyanvenkatesh9523]

F0 value development?

[@md.shahidul9013]

Nice,My question,what’s area is required for terminal sterilizer,is non class area okay? Please give answers with reference

[@PHARMAVEN]

After filling and sealing, the product is basically finished product and doesn't need to store in classified area. For terminal stabilizer, CNC (Controlled Non Classified) area is acceptable

[@niravbhatt1473]

Thanks sir Temperature mapping required in what size containers?

[@PHARMAVEN]

100 ml and above

[@marwanfahmy8608]

If i use over kill approach of 8log reduction why i consider 121/10min cycle not a Sterilization cycle.and what is the minimum time parameters if I need to change for higher temperature as 134.knowing that f0 is12.... thanks.

[@PHARMAVEN]

Overkill depends upon D value of product, for example if D value is 1, then 121 degree C at 10 minutes will give 10 log reduction, Overkill means 12 log reduction.

[@AnilSingh-hg5pz]

How vials are kept inverted or upright during ts

[@PHARMAVEN]

Upright only during terminal Sterilization

[@bholuyadav9276]

Which guidelines is for terminal sterilization please reply

[@PHARMAVEN]

European guide: Guideline on the Sterilisation of the medicinal product, active substance, excipient and primary container USFDA: Guidance for Industry Submission of Documentation in Applications for Parametric Release of Human and Veterinary Drug Products Terminally Sterilized By Moist Heat Process

[@kalyanvenkatesh9523]

Who will fix F0 value sir.

[@ashishmishra3752]

Nice video