Tetralogy of Fallot (Year of the Zebra)

What is Tetralogy of Fallot? Tetralogy of Fallot (TOF) is a congenital heart condition characterized by four heart abnormalities-stenosis in the right ventricular outflow tract, right ventricular hypertrophy, ventricular septal defect, and aortic override of septal defect. Together, these can cause cyanosis in the newborn.
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[@stephenbartowski2954]

What a beautiful explanation. Congrats to all the people involved

[@osmosis]

Hi Stephen! Thanks! ❤️

[@IvyTapales119]

This video has provided me with such better explanation compared to the ones we've been taught in med school. Thank you for simplifying things for us and making difficult topics easier and more understandable. This will help me a lot in our board exam. Keep up the good work!!

[@osmosis]

You're very welcome, Ivy! 🥰❤️🙏🏼

[@vinceceejay]

Thank you for this simplfied explanation

[@binoymathew246]

This is a well layed out presentation. Thank you. 🙏

[@osmosis]

Most welcome! ❤️

[@wqrkhn7755]

Stunning…….GREAT AFFORT….love it

[@osmosis]

Many thanks! 😊

[@medicalminutia]

such an insightful video. I have heard that TOF is somehow correlated with DiGeorge and Chromosome 22 deletions and was wondering if you could explain more about those conncetions. Or, are there videos on it too? To recapitulate the pathophysiology of TOF, the pressure difference reverses because it somehow gets too high in the right ventricle, shunting back into the left ventricle, resulting in some quantity that may vary in severity levels of deoxygenated blood pumping out through the left ventricle --> aorta --> systemic circulation, sometimes (in approx what proportion of cases?) results in cyanosis or blue-ish discoloration due to lacking adequate oxygenation of systemic body tissues if i follow you correctly. and, how exactly can squatting can help reverse the condition by elevating systemic pressure and left ventricular pressure because if the RV pressure is high, I do not see how squatting would equilibrate only the LV and not travel through the heart, increased opening or dilatation between the RV and LV

[@mithra8144]

Thank you so much for such a Great explanation.

[@osmosis]

You're very welcome! 😊

[@christinesalami7712]

Great way to learn with you guys thanks for all the osmosis team ❤❤

[@osmosis]

Our pleasure! 💖

[@jibinjose7305]

In this flowchart at 4:58 ,it'd have been better if the initial steps were like "increased physical activity --> peripheral vasodilatation--> dec. Peripheral resistance --> more R-L shunt--> dec O2 sat.-->Cyanosis" that could've made the "thinking" more easier too😅😊

[@MrJayPuff]

This was a truly fantastic video and explanation. I really could not explain anything better than this video, and really clarified this disease.

[@osmosis]

Thank you! 🙏🏼

[@fernandapaiva6420]

You all finally got me to understand this. Thank you SO much

[@osmosis]

Happy to help, Fernanda! ❤️

[@roxannlegg750]

Best video of TOF i have seen. I REALLy wish this had been available when i was at uni during my degree several years ago. It messed with my head - but this is the simplest explanation ever!

[@osmosis]

Thank you! 💕

[@randomlyaccepted5215]

Thanks for this! I have TOF, its nice to understand my condition a bit more.

[@osmosis]

Glad it was helpful! 🥰❤️🙏🏼

[@user-hr1yu6li9w]

You okay?

[@hieker5656]

this video is amazing! i have an assignment where i have to explain Tetralogy of Fallot. this helps me so much, its calmly explained ( a very nice voice to listen to) with very well fitted animations, as a person with ADHD its easy to focus on whats being said because of this. thank you for explaining this congenital heart condition so well!!!

[@osmosis]

We're glad that our video helped! 💫 🥰 💖

[@cardiyansane1414]

Outstanding and concise thank you!❤

[@osmosis]

Welcome! ❤️

[@Jojin_badass]

It was so helpful. Thanks for the video

[@osmosis]

You're welcome! 💕

[@mridulsharma1518]

Really great 🙏 and you made it so easy to understand the lecture.

[@osmosis]

Glad to help! 😊

[@huwguyver4208]

Very clear and informative, thankyou!

[@osmosis]

You're very welcome! 🙌🏼

[@Blackgeek0]

Well understood, thank you!

[@osmosis]

You're welcome, Sandra! 💕

[@nuzhatnoshin295]

Very good explanation 😊

[@taneishatomlinson7137]

This was great. Thanks!

[@osmosis]

You're welcome! ❤️

[@dexeuromatprywatny388]

I'm a Zebra with TOF number 4. Great information better than wikipedia articles.

[@osmosis]

Thank you! 🙏🏼

[@soniasun1]

Thank you for your help.

[@osmosis]

Always glad to help! ❤️

[@AnshuKumari-wc9cw]

Well explained,it really helped me

[@osmosis]

We're delighted to know this helped! 🥰

[@jankeishkaur7226]

Amazing explanation

[@osmosis]

Thank you! 😊

[@methaqsalah2520]

Alot of love

[@Mr.anonymous1137]

Thank you so much.. such a amazing explanation😁😁😁

[@osmosis]

Most welcome! 😊

[@iSankalp]

The way you teach me 🤩

[@lolakhalid0504]

You are saving my life ❤

[@osmosis]

Happy to help! 👍🏼

[@sayantikasingha5325]

So helpful....same words written in my book...but difficulty in understanding... thank you so much

[@osmosis]

Happy to help 🥰❤️🙏🏼

[@sewpungyow5154]

How do babies come to squat in order to relieve a tet spell? Is it instinctive or do they just figure it out? Or does it just happens because they get woozy?

[@nidhisingh-kl2jw]

You’re a saviour ❤️

[@osmosis]

❤️ ❤️ ❤️

[@PriyankaKumari-io6pf]

Easiest way to learn....Thanku so much 🙏

[@osmosis]

Most welcome, Priyanka! 😊

[@user-ty5fb8yz7j]

Thanks

[@osmosis]

Welcome! 💕

[@omerfarooq5517]

Osmosis 👍

[@caracatitafrumoasa7319]

What does the aorta overriding the septal defect do?

[@ritikadhaygonde2923]

Take the blood from right ventricles and pumps it out

[@user-uw7ms4tt2m]

❤

[@rightventricle5147]

6:00

[@ronefana4015]

❤❤❤

[@heriethmwamba9559]

👍👍👍

[@user-eu5dr4bo6n]

ماهو الاحل

[@user-aaadanah]

سترنا الله ..عربي اقل شي اكتب صح؟؟

[@razb3129]

الي قالوه عملية في اول سنة شفى الله احبابكم