The Complement System: Classical, Lectin, and Alternative Pathways

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Professor Dave Explains

Professor Dave Explains

Күн бұрын

Пікірлер: 228
@Liberperlo
@Liberperlo 3 жыл бұрын
This is the best video on complement I have seen. I'm not an immunologist or even a student. Just a librarian who is fascinated by the immune system. Thanks!
@Fidel5555
@Fidel5555 2 жыл бұрын
Wow! You've inspired me...I'm a medical student and find this stuff boring yet you're not even a student but study immunology voluntarily, congrats
@spvillano
@spvillano 2 жыл бұрын
@@Fidel5555 I've always said, I'll stop learning maybe, just maybe three days after I'm dead. ;) No reason to not study various things, as knowledge is power. Back when I was in the Army (retired in 2010), I ran into not one, but two cases of pheochromocytoma. One was recognized late, the soldier was to begin treatment after field training, but expired from a ruptured AAA. The other, I pieced together what was going on, asked doctor to do me a favor and run a couple extra tests and there it was, he had pheochromocytoma. His problem was quickly addressed and he returned to duty. So, that trivia can and does save lives. Diagnosing things, just Boolean flow really. I do Boolean algebra and regular expressions in my head as part of my job. :) Annoyingly, basic math tends to give me trouble, but that's what calculators or if I had to, fall back to a slide rule is for.
@Dannalasapa
@Dannalasapa 2 жыл бұрын
@@Fidel5555 same this is the class I’m hating the most so far but I think it’s mostly bc my prof is absolutely awful
@bjrnaaron
@bjrnaaron 2 жыл бұрын
Beautiful ❤
@IPlayAces
@IPlayAces Жыл бұрын
couldn't agree more- coming from a physician/scientist who's heard many (attempted) explanations of complement systems. this is pure gold. never heard such a clear cut explanation
@emdoubleyew3788
@emdoubleyew3788 3 жыл бұрын
This makes re-reading my immunology textbook nearly painless. Lovely stuff you have.
@spvillano
@spvillano 2 жыл бұрын
This and similar courses makes things a lot easier to recognize hydrophobic parts and lipophilic parts of some carbon chains. That helps me understand some odd points in the pharmacology of some medications.
@alemantewassie6695
@alemantewassie6695 10 ай бұрын
This was the best video I have ever watched about Complement system. Only someone who have left a few minutes left to cover this topic knows how fantastic this work is. Thank you Prof Dave.
@sumeet9367
@sumeet9367 2 жыл бұрын
Professor Dave, I am an MS1(first year medical student) and my first block includes immunology. I wanted to say your videos including this complement protein video are more concise than the lectures from my immunology professor. Thank you!
@its_not_lux
@its_not_lux 9 ай бұрын
nibba you didn't have to say anything other than 'first year med'. MS1😵‍💫
@anoud6059
@anoud6059 5 ай бұрын
Same
@Hannah-yz7gj
@Hannah-yz7gj 2 жыл бұрын
you don't know how much you helped me understand this topic. i was on the verge of crying going through our readings but this video really clarified a lot of things (for some reason it seemed like our lecturers were also speaking a whole different language while teaching this). thank you so much!
@MissD333
@MissD333 Жыл бұрын
This is really excellent. Also the speed at which you speak is perfect for people who are trying to understand something, other videos I have to pause and re listen because they’re talking too fast, but this is perfect!
@dmskarunaratne80
@dmskarunaratne80 2 жыл бұрын
no words. simplistic way to teach complex theory with best illustrations. thank you. Best video on this topic.
@Sydney-gk8gh
@Sydney-gk8gh 17 күн бұрын
This is by far the most clear yet comprehensive breakdown of these pathways that I have seen. Thank you so much, you just tied together so many loose ends from days of studying!
@bethuelmutiti2089
@bethuelmutiti2089 2 жыл бұрын
I really don't know how my Med School would be without you sir 😭🙏❤️🔥. A Big thanks to you for making my life easy
@whbclaire
@whbclaire Жыл бұрын
Thank you so much for this. In my role as a medical writer, I have been doing some programs on paroxysmal nocturnal hematoglobinuria, which is a disease of the complement cascade. This clearly explained a lot of the things I was confused about.
@zhaomengna4800
@zhaomengna4800 2 жыл бұрын
Very detailed and direct illustration and description. Learn more from these lectures. Thanks a lot.
@shaqthedoc4376
@shaqthedoc4376 3 жыл бұрын
dude you just cleared the evolutionary aspect of the complement system, great job👍🏻
@ValeriaSteiger
@ValeriaSteiger Ай бұрын
Thank you soooo much, seriously! After studying medicine for 4 yrs i did not just learn it by heart, but understood it
@sagacious_Codyt
@sagacious_Codyt 2 жыл бұрын
This has been really helpful. I've been struggling to understand the complement cascade but with how you've laid everything out, I'm subliming.. .. Thank you so much
@wassyjalal8447
@wassyjalal8447 2 ай бұрын
I used to watch your videos way back in high school for AP bio and your videos are still carrying me as a first year medical student lmaooo. Could not have made it where I am today without you
@ProfessorDaveExplains
@ProfessorDaveExplains 2 ай бұрын
email me a video summarizing this in 10-20 seconds for my upcoming 10th anniversary video!
@GolgiGuy102
@GolgiGuy102 Жыл бұрын
I really appreciate the evolutionary context. Really outs things into better perspective!
@immune01
@immune01 9 ай бұрын
Very comprehensive with just enough detail for competence but not too overwhelming!
@madelinegreene8031
@madelinegreene8031 2 жыл бұрын
I have an immunology test next week for my first year of grad school--this has been SO much more helpful than anything my professor has said!
@birukgossaye2187
@birukgossaye2187 3 жыл бұрын
Hey Professor, I understand almost everything you explain so please start makin videos about music theory and all. You're the best teacher ever.
@samgas1219
@samgas1219 3 жыл бұрын
He knows alot about the SCIENCE stuff, unfortunately music theory is not a science.
@AlvinturesTV
@AlvinturesTV 3 жыл бұрын
Just on time for my quiz on this topic!
@pamtarlow
@pamtarlow Жыл бұрын
Great video. I am a pharmacist trying to help my patients with Long Covid and appreciate the excellent education here.
@ferhanslamang370
@ferhanslamang370 2 ай бұрын
I had no idea where all these complement proteins came from, but you simplified it really well for me.
@Paraselene_Tao
@Paraselene_Tao 3 жыл бұрын
I'm so glad that you're making these lectures. I considered months ago that the US population (from high school and up) needs to learn how the immune system works. If we know how the immune system works then we will all understand and agree on something like a vaccine. Thank you for spreading this information.
@spvillano
@spvillano 2 жыл бұрын
Indeed, the problems with COVID seems to be that leukocytes are being infected, interfering with their response, while innate responses are also being blunted. By the time the immune system notices that the infection was unaddressed, it went into scorched earth mode (to oversimplify it by a lot) and that's the cytokine storm of COVID-19 and the Spanish Flu.
@whbclaire
@whbclaire Жыл бұрын
You are so spot on! If more people understood immunology, we would haver far fewer ridiculous conspiracy lies circulating about vaccines!
@almaalcala3887
@almaalcala3887 3 жыл бұрын
Thanks!
@adamhartz5483
@adamhartz5483 3 жыл бұрын
Professor Dave.... This video is great. It helped me understand the video much better.
@kedarnathlivedarshanbhakti9715
@kedarnathlivedarshanbhakti9715 Жыл бұрын
Saw so many videos.. But finally got clarity in this one
@genero2008
@genero2008 Ай бұрын
Easy but comprehensive lecture. the best of the best to me.
@StoutShako
@StoutShako 3 жыл бұрын
WOOOO YEAAAH, BABY THAT'S WHAT I'VE BEEN WAITING FOOOOR WOOOO!
@samreenkomal3837
@samreenkomal3837 Жыл бұрын
I've been a subscriber since 2016. It's amazing how easy you make things seem easy for us❤❤❤ Lots of love Professor!!❤️
@studyvlogcute
@studyvlogcute 3 ай бұрын
it was great. thank you, i really had a problem undrestanding complement system but you made it so easy to undrestand.
@allofme835
@allofme835 2 жыл бұрын
Love your teaching skills to visual learners. You make studying easier 🥳🥳
@palantir135
@palantir135 3 жыл бұрын
I had to learn all this a long time ago. Thanks for the update.
@TikoPiko
@TikoPiko 3 жыл бұрын
@Professor Dave Explains, I have come to purchase your book through my enjoyment of your KZbin content. I must say that I find it very insightful, succint and a refreshing read overall. I look forward to more from you, as you definitely posess great talent. P.S.: on page 18 there is a helium atom representation with the subtext implying that it is in colour, when in fact at least my edition is grayscale. Just a (hopefully) helpful note.
@marinahovakimyan9387
@marinahovakimyan9387 2 жыл бұрын
Thank you so so so much! Amazing explanation and illustration! Thank you for your effort.
@abigailwatson3330
@abigailwatson3330 2 жыл бұрын
Thank you thank you thank you, was not understanding this from textbooks or my lecturers! your videos are the best!
@reeveeakt7250
@reeveeakt7250 3 жыл бұрын
Animal immune system are really well made... Amazing presentation!
@basiabarbara3365
@basiabarbara3365 3 жыл бұрын
Your videos are so helpful to me, thank you🙏🏻
@zarghunarakheel3829
@zarghunarakheel3829 5 ай бұрын
It's strange how Years of crazy cramming could be resolved one simple vedio.. you did a great job here.
@moon_loverr
@moon_loverr 2 жыл бұрын
Your videos are amazing, makes immunology easier, making my day😊 Thanks Professor wish u all success.
@robjoemama2466
@robjoemama2466 11 ай бұрын
Excellent video!! I have a better understanding of the Complement system now. I'll recommend this to my classmates to watch. 👏👏👏👏👏👏👏👏👏👏
@AndzileDlamini-ju4yw
@AndzileDlamini-ju4yw 5 ай бұрын
I just paused the video to tell you that you a legend Professor Dave🤝🙏🐐
@djmaamis3167
@djmaamis3167 2 ай бұрын
I'm m1( first year medical student) Sir you are helped me alot in my immunology module ❤🎉
@nuriatnamatovu
@nuriatnamatovu Жыл бұрын
Just the best I heard about the compliment system , long live
@josephntowannobil4571
@josephntowannobil4571 Жыл бұрын
Superb explanation on Complement System. I love this video
@theadorablea7469
@theadorablea7469 3 ай бұрын
there is no video in german, which explains it so well, thanks!!
@shria__7870
@shria__7870 Жыл бұрын
really made such an intimidating topic so easy to understand! thank you Professor Dave :))
@karina3133
@karina3133 Жыл бұрын
Extremely good video about Complement, saved me. Thank you!
@danjbro
@danjbro 3 жыл бұрын
Well done Dave! 👏🏽
@beaniebaby_rei
@beaniebaby_rei 3 жыл бұрын
You're a God send
@ahmedeldimllawi5092
@ahmedeldimllawi5092 Жыл бұрын
ur awesome and this is the best video on complement i have seen
@santicruz4012
@santicruz4012 3 жыл бұрын
Thanks professor Dave!
@PRAGNAGOLDER-d9x
@PRAGNAGOLDER-d9x Ай бұрын
Nicely explained! May God bless you.
@Lulla3sl
@Lulla3sl Жыл бұрын
BEST EXPLANATION EVER!!
@datimbangnorminah1956
@datimbangnorminah1956 2 жыл бұрын
Thank you for helping me learn our lesson in Serology
@equalizerz3107
@equalizerz3107 2 ай бұрын
Great job professor !! so beneficial
@user-cj8bu7qq4o
@user-cj8bu7qq4o 2 жыл бұрын
Great presentation on complement pathway!
@codeyds6769
@codeyds6769 Ай бұрын
As a first year medical student, thank you.
@israelojo6875
@israelojo6875 Жыл бұрын
Excellent sir. You are doing extremely well. This is really great and highly explanatory, infact completely.
@lexthevi
@lexthevi Жыл бұрын
Damn Man just explained the gibberish in my Professor's slide perfectly. Ready for this exam now.
@umanamicheal8089
@umanamicheal8089 9 ай бұрын
Oodles of thanks, Professor Dave.
@janeszz
@janeszz 3 жыл бұрын
Hey, really like your videos, especially the ones where you debunk conspiracy theories. I recently saw something about Tesla's radiance energy curcuit. It is suggestet that this would be able to supply everybody with free energy but companies dont want us to know about it because we should pay for their energy. Maybe that could be a video idea. Keep on the great work!
@santanudebnath9617
@santanudebnath9617 11 ай бұрын
You're doing really good. Best wishes
@nouf1406
@nouf1406 Жыл бұрын
How am I supposed to memorize all of this?
@Abderrahmane-zq3bw
@Abderrahmane-zq3bw 4 ай бұрын
it’s FAR better than those long azz med school lectures… mine is literally 100 slides
@dohagouyd3997
@dohagouyd3997 2 жыл бұрын
I would like to give you a huge thank for this video! you saved me fr
@drmadhavmehta
@drmadhavmehta 9 ай бұрын
Great video Professor!
@1rrrrrrrrrrr544f
@1rrrrrrrrrrr544f 7 ай бұрын
Can't be explained better ❤❤❤❤
@sarahmsoh5482
@sarahmsoh5482 2 жыл бұрын
How can one fail to subscribe. Best video on Complement
@minashin1562
@minashin1562 Жыл бұрын
My man has the best intro ever 👍
@synasanchouli8511
@synasanchouli8511 3 жыл бұрын
Your videoes better than faradars immunology course
@XtinaThaiFan
@XtinaThaiFan 3 жыл бұрын
This is amazing. Thank youuuu 😍❤❤
@craigcooper5060
@craigcooper5060 2 жыл бұрын
Really good review of the complement system... Thanks for posting!
@teresajadia3291
@teresajadia3291 2 жыл бұрын
I am a licensed medical technologist and I'm studying for my second license this coming October. Complement system always ALWAYS aggravate the shit out of me. This lecture gave me atleast an idea what to remember 😅
@BokangMofomme
@BokangMofomme Жыл бұрын
This amazing! and easily to follow, thank you prof Dave
@mahkishouma314
@mahkishouma314 3 ай бұрын
thanks a lot! i watched it twice
@balamicroworld7
@balamicroworld7 Ай бұрын
Thank you so much 🙏🏻.You explain so well.
@il3354
@il3354 2 жыл бұрын
Very well explained. Thank you!
@sonasunil1748
@sonasunil1748 6 ай бұрын
Hey one teeny tiny mistake that caught my eyes :- C3 convertase = C4b2a ryt? It shows 2b ( 4:37). Great video. Keep posting!!❤❤
@PahlaChenjerai
@PahlaChenjerai Жыл бұрын
this vid is superb, it's best for understanding
@jessicalv6442
@jessicalv6442 Жыл бұрын
Save my life!!! Thank you!!!
@mayar9078
@mayar9078 3 жыл бұрын
Great explanation , thanks 💕
@chihchengh
@chihchengh 3 жыл бұрын
Really good!
@zahrap906
@zahrap906 Ай бұрын
really excellent video,thanks so much❤
@umanamicheal8089
@umanamicheal8089 9 ай бұрын
Very explicit and comprehensive.✌️👍👍
@ClashergodClashergod
@ClashergodClashergod 11 ай бұрын
great video
@fatimayasir9115
@fatimayasir9115 2 жыл бұрын
Really great job, thanks a lot!
@saraalmasri2107
@saraalmasri2107 17 күн бұрын
just perfect lots of thanks professor
@Sabrinaaa_97
@Sabrinaaa_97 Ай бұрын
شكراً جزيلاً ❤❤❤
@SaeedaKuvadia
@SaeedaKuvadia 2 жыл бұрын
better than my uni lectures!!
@zahramashhadi4288
@zahramashhadi4288 2 жыл бұрын
It is very helpful. thank you so much
@billiee_96
@billiee_96 6 күн бұрын
Amazing! Thank you so much
@sandaruariyawansa6765
@sandaruariyawansa6765 2 жыл бұрын
Thank you so much for the explanation!
@arunshankar814
@arunshankar814 6 ай бұрын
Awesome video 👌
@nadernayo
@nadernayo 3 жыл бұрын
Thanks...Great knowledge..
@amiraboumerah4645
@amiraboumerah4645 14 күн бұрын
Simple and effective !! 💚💚😍😍😍
@Sciencstudent
@Sciencstudent 28 күн бұрын
Thank you sir so much, this video was vary helpful
@chrisopaka10
@chrisopaka10 2 жыл бұрын
So currently, 12/10/2022 has C4b2b been officially adopted and is now officially used or is C4b2a debatable?? Prof please?🙏🙏
@alexisc5358
@alexisc5358 3 жыл бұрын
This has been so helpful. MY TEXTBOOK uggg!
@akubasco
@akubasco 2 жыл бұрын
thanks for making this video.Very helpful.
@SperahHygaru
@SperahHygaru 13 күн бұрын
Good lecture💯
@RfR442
@RfR442 Жыл бұрын
Prof for a reason
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